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CMR reference values

Adriana D M Villa, Laura Corsinovi, Ioannis Ntalas, Xenios Milidonis, Cian Scannell, Gabriella Di Giovine, Nicholas Child, Catarina Ferreira, Muhummad Sohaib Nazir, Julia Karady, Esmeralda Eshja, Viola De Francesco, Nuno Bettencourt, Andreas Schuster, Tevfik F Ismail, Reza Razavi, Amedeo Chiribiri
BACKGROUND: Clinical evaluation of stress perfusion cardiovascular magnetic resonance (CMR) is currently based on visual assessment and has shown high diagnostic accuracy in previous clinical trials, when performed by expert readers or core laboratories. However, these results may not be generalizable to clinical practice, particularly when less experienced readers are concerned. Other factors, such as the level of training, the extent of ischemia, and image quality could affect the diagnostic accuracy...
November 19, 2018: Journal of Cardiovascular Magnetic Resonance
Alejandra García-Baizán, Maite Millor, Pablo Bartolomé, Ana Ezponda, Jesús C Pueyo, Juan J Gavira, Gorka Bastarrika
To evaluate the vasodilator effect of adenosine triphosphate (ATP) compared with adenosine in stress perfusion cardiac magnetic resonance (CMR) examinations. A total of thirty-three patients underwent clinically indicated stress/rest perfusion CMR examination following intravenous injection of a total dose of 0.2 mmol/kg of gadobutrol. Individuals were randomly assigned to ATP (160 mcg/kg/min) or adenosine (140 mcg/kg/min). The vasodilator effect of both drugs was analyzed by comparing differences in heart rate, symptoms during stress, and semiquantitative myocardial and splenic perfusion parameters, including time, time to peak, upslope, myocardial perfusion reserve index, tissue perfusion values, splenic and myocardial signal intensity ratios, and splenic-to-myocardial signal intensity ratios...
November 13, 2018: International Journal of Cardiovascular Imaging
Zhiyong Chen, Bin Sun, Qing Duan, Yunjing Xue, Lianglong Chen
To evaluate the accuracy of contrast-enhanced whole-heart magnetic resonance coronary angiography at 3.0T for assessing significant stenosis (≥50% lumen diameter reduction) in patients with myocardial infarction, by using conventional coronary artery angiography as the reference standard, and also test the performance of that for the detection and assessment of chronic myocardial infarction (MI), compared with standard delayed-enhancement coronary magnetic resonance (DE-CMR) for the determination of infarct size...
November 2018: Medicine (Baltimore)
Jee Young Min, Sung Min Ko, In Young Song, Jung Geun Yi, Hweung Kon Hwang, Je Kyoun Shin
Objective: To compare the diagnostic performance of cardiovascular magnetic resonance (CMR) myocardial perfusion at 1.5- and 3-tesla (T) for detecting significant coronary artery disease (CAD), with invasive coronary angiography (ICA) as the reference method. Materials and Methods: We prospectively enrolled 281 patients (age 62.4 ± 8.3 years, 193 men) with suspected or known CAD who had undergone 1.5T or 3T CMR and ICA. Two independent radiologists interpreted perfusion defects...
November 2018: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
Tar-Choon Aw, Wei-Ting Huang, Thu-Thao Le, Chee-Jian Pua, Briana Ang, Soon-Kieng Phua, Khung-Keong Yeo, Stuart A Cook, Calvin W L Chin
The 99th percentile upper reference limits (URL) of high-sensitivity cardiac troponin (hs-cTn) in healthy subjects are essential for diagnosis and management of cardiovascular diseases. Unless screened stringently, subclinical disease affects the derived URL. In 779 healthy subjects(49% males; 17-88 years) screened by cardiovascular magnetic resonance (CMR), the gold standard for assessing cardiac volumes and myocardial mass; and estimated glomerular filtration rate (eGFR), the 99th percentile URL of hsTnT (Roche) and hs-cTnI (Abbott) were similar to the published URL...
October 18, 2018: Scientific Reports
Chrysanthos Grigoratos, Giancarlo Todiere, Giovanni Donato Aquaro, Andrea Barison
Cardiac palpitations secondary to ventricular ectopic beats are a frequent clinical indication for a cardiac magnetic resonance (CMR) scan. CMR has already demonstrated its additive diagnostic value in patients with frequent arrhythmias even when echocardiogram appears normal. Hereby, we describe a case of a middle-aged male patient referred to our laboratory because of frequent ventricular ectopic beats and an inconclusive echocardiogram due to an extremely poor acoustic window. A diagnosis of pericardial agenesis (PA) was made explaining patient symptoms and arrhythmias previously detected...
July 2018: Journal of Cardiovascular Echography
Idan Roifman, Feng Qiu, Kim A Connelly, Graham A Wright, Michael Farkouh, Laura Jimenez-Juan, Harindra C Wijeysundera
OBJECTIVES: Cardiovascular magnetic resonance (CMR) imaging is the gold-standard test for the assessment of heart function. Despite its importance, many jurisdictions lack specific billing codes that can be used to identify patient receipt of CMR in administrative databases, limiting the ability to perform 'big data' CMR studies. Our objective was to identify the optimal billing code combination to identify patients who underwent CMR using administrative data in Ontario. DESIGN: Retrospective cohort study...
October 8, 2018: BMJ Open
Massimo Imazio, Gloria Angelico, Monica Andriani, Luisa Lobetti-Bodoni, Ottavio Davini, Carla Giustetto, Mauro Rinaldi
Recent data suggest that myocardial septal late gadolinium enhancement (LGE) may have an independent prognostic value in patients with acute myocarditis undergoing cardiac magnetic resonance (CMR). Aim of the present study is to evaluate its prevalence and prognostic implications in these patients with or without preserved LV function. Retrospective cohort study including all cases of clinically suspected acute myocarditis referred for CMR. A diagnosis of acute myocarditis was confirmed by CMR according to Lake Louise Criteria...
September 13, 2018: American Journal of Cardiology
Daniele Muser, Pasquale Santangeli, Joseph B Selvanayagam, Gaetano Nucifora
Ventricular Arrhythmias (VAs) may present with a wide spectrum of clinical manifestations ranging from mildly symptomatic frequent premature ventricular contractions to life-threatening events such as sustained ventricular tachycardia, ventricular fibrillation and sudden cardiac death. Myocardial scar plays a central role in the genesis and maintenance of re-entrant arrhythmias which are commonly associated with SHD such as ischemic heart disease, healed myocarditis and non-ischemic cardiomyopathies. However, the arrhythmogenic substrate may remain unclear in up to 50% of the cases after a routine diagnostic workup comprehensive of 12-lead surface ECG, transthoracic echocardiography and coronary angiography/computed tomography...
September 24, 2018: Current Cardiology Reviews
Sebastian Bohnen, Maxim Avanesov, Annika Jagodzinski, Renate B Schnabel, Tanja Zeller, Mahir Karakas, Jan Schneider, Enver Tahir, Ersin Cavus, Clemens Spink, Ulf K Radunski, Francisco Ojeda, Gerhard Adam, Stefan Blankenberg, Gunnar K Lund, Kai Muellerleile
BACKGROUND: The purpose of this work is to describe the objectives and design of cardiovascular magnetic resonance (CMR) imaging in the single center, prospective, population-based Hamburg City Health study (HCHS). The HCHS aims at improving risk stratification for coronary artery disease (CAD), atrial fibrillation (AF) and heart failure (HF). METHODS: The HCHS will finally include 45,000 inhabitants of the city of Hamburg (Germany) between 45 and 74 years who undergo an extensive cardiovascular evaluation and collection of biomaterials...
September 24, 2018: Journal of Cardiovascular Magnetic Resonance
Junping Peng, Xiaodan Zhao, Lei Zhao, Zhanming Fan, Zheng Wang, Hui Chen, Shuang Leng, John Allen, Ru-San Tan, Angela S Koh, Xiaohai Ma, Mingwu Lou, Liang Zhong
Reference values on atrial and ventricular strain from cardiovascular magnetic resonance (CMR) are essential in identifying patients with impaired atrial and ventricular function. However, reference values have not been established for Chinese subjects. One hundred and fifty healthy volunteers (75 Males/75 Females; 18-82 years) were recruited. All underwent CMR scans with images acceptable for further strain analysis. Subjects were stratified by age: Group 1, 18-44 years; Group 2, 45-59 years; Group 3, ≥60 years...
2018: Frontiers in Physiology
Shadi Akhtari, Michael L Chuang, Carol J Salton, Sophie Berg, Kraig V Kissinger, Beth Goddu, Christopher J O'Donnell, Warren J Manning
BACKGROUND: Left bundle branch block (LBBB) is associated with abnormal left ventricular (LV) contraction, and is frequently associated with co-morbid cardiovascular disease, but the effect of an isolated (i.e. in the absence of cardiovascular dissease) LBBB on biventricular volumes and ejection fraction (EF) is not well characterized. The objective of this study was to compare LV and right ventricular (RV) volumes and EF in adults with an isolated LBBB to matched healthy controls and to population-derived normative values, using cardiovascular magnetic resonance (CMR) imaging...
September 20, 2018: Journal of Cardiovascular Magnetic Resonance
Alberto Cipriani, Alessandro Zorzi, Patrizio Sarto, Martino Donini, Ilaria Rigato, Riccardo Bariani, Manuel De Lazzari, Kalliopi Pilichou, Gaetano Thiene, Sabino Iliceto, Cristina Basso, Domenico Corrado, Martina Perazzolo Marra, Barbara Bauce
BACKGROUND: Exercise-induced ventricular arrhythmias (EIVA) in young athletes raise the suspicion of an underlying heart disease at risk of sudden death. OBJECTIVE: We aimed to assess the prevalence and determinants of abnormal cardiac magnetic resonance (CMR) findings in athletes referred for EIVA vs non-EIVA with negative or inconclusive echocardiography. METHODS: We performed CMR in a consecutive series of athletes aged 15-50 years referred for frequent (>500 per day) or repetitive premature ventricular beats...
August 30, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Einat Slonimsky, Osnat Konen, Elio Di Segni, Eliyahu Konen, Orly Goitein
BACKGROUND: Correct diagnosis of cardiac masses is a challenge in clinical practice. Accurate identification and differentiation between cardiac thrombi and tumors is crucial because prognosis and appropriate clinical management vary substantially. OBJECTIVES: To evaluate the diagnostic performances of cardiac magnetic resonance imaging (CMR) in differentiating between cardiac thrombi and tumors. METHODS: A retrospective review of a prospectively maintained database of all CMR scans was performed to distinguish between cardiac thrombi and tumors during a 10 year period in a single academic referral center (2004-2013)...
August 2018: Israel Medical Association Journal: IMAJ
Clément Cholet, Thibaud Damy, François Legou, Hicham Kobeiter, Alain Rahmouni, Jean-François Deux
RATIONALE AND OBJECTIVES: Diagnosis of cardiac amyloidosis (CA) on cardiac magnetic resonance (CMR) can be challenging and quantitative indexes are relevant to further characterize the myocardium. We hypothesize that the relative myocardial enhancement measured from pre and post contrast cine imaging provides diagnostic information for CA in the setting of left ventricular hypertrophy (LVH). MATERIALS AND METHODS: Patients with LVH referred to our center and control subjects with normal CMR were retrospectively included...
July 31, 2018: Academic Radiology
Mahesh Bharath Keerthivasan, Sagar Mandava, Kevin Johnson, Ryan Avery, Rajesh Janardhanan, Diego R Martin, Ali Bilgin, Maria I Altbach
BACKGROUND: Double inversion recovery (DIR) fast spin-echo (FSE) cardiovascular magnetic resonance (CMR) sequences are used clinically for black-blood T2-weighted imaging. However, these sequences suffer from slice inefficiency due to the non-selective inversion pulses. We propose a multi-band (MB) encoded DIR radial FSE (MB-DIR-RADFSE) technique to simultaneously excite two slices. This sequence has improved signal-to-noise ratio per unit time compared to a single slice excitation. It is also motion robust and enables the reconstruction of high-resolution black-blood T2-weighted images and T2 maps for the excited slices...
July 19, 2018: Journal of Cardiovascular Magnetic Resonance
Olivier Bernard, Alain Lalande, Clement Zotti, Frederick Cervenansky, Xin Yang, Pheng-Ann Heng, Irem Cetin, Karim Lekadir, Oscar Camara, Miguel Angel Gonzalez Ballester, Gerard Sanroma, Sandy Napel, Steffen Petersen, Georgios Tziritas, Elias Grinias, Mahendra Khened, Varghese Alex Kollerathu, Ganapathy Krishnamurthi, Marc-Michel Rohe, Xavier Pennec, Maxime Sermesant, Fabian Isensee, Paul Jager, Klaus H Maier-Hein, Peter M Full, Ivo Wolf, Sandy Engelhardt, Christian F Baumgartner, Lisa M Koch, Jelmer M Wolterink, Ivana Isgum, Yeonggul Jang, Yoonmi Hong, Jay Patravali, Shubham Jain, Olivier Humbert, Pierre-Marc Jodoin
Delineation of the left ventricular cavity, myocardium, and right ventricle from cardiac magnetic resonance images (multi-slice 2-D cine MRI) is a common clinical task to establish diagnosis. The automation of the corresponding tasks has thus been the subject of intense research over the past decades. In this paper, we introduce the "Automatic Cardiac Diagnosis Challenge" dataset (ACDC), the largest publicly available and fully annotated dataset for the purpose of cardiac MRI (CMR) assessment. The dataset contains data from 150 multi-equipments CMRI recordings with reference measurements and classification from two medical experts...
November 2018: IEEE Transactions on Medical Imaging
Louise A E Brown, Sebastian C Onciul, David A Broadbent, Kerryanne Johnson, Graham J Fent, James R J Foley, Pankaj Garg, Pei G Chew, Kristopher Knott, Erica Dall'Armellina, Peter P Swoboda, Hui Xue, John P Greenwood, James C Moon, Peter Kellman, Sven Plein
BACKGROUND: Non-invasive assessment of myocardial ischaemia is a cornerstone of the diagnosis of coronary artery disease. Measurement of myocardial blood flow (MBF) using positron emission tomography (PET) is the current reference standard for non-invasive quantification of myocardial ischaemia. Dynamic myocardial perfusion cardiovascular magnetic resonance (CMR) offers an alternative to PET and a recently developed method with automated inline perfusion mapping has shown good correlation of MBF values between CMR and PET...
July 9, 2018: Journal of Cardiovascular Magnetic Resonance
Hanwei Chen, Xueping He, Guoxi Xie, Jianke Liang, Yufeng Ye, Wei Deng, Zhuonan He, Dexiang Liu, Debiao Li, Xin Liu, Zhaoyang Fan
BACKGROUND: The aim was to investigate the feasibility of a cardiovascular magnetic resonance (CMR) black-blood thrombus imaging (BBTI) technique, based on delay alternating with nutation for tailored excitation black-blood preparation and a variable flip angle turbo-spin-echo readout, for the diagnosis of acute deep vein thrombosis (DVT) at 1.5 T. METHODS: BBTI was conducted in 15 healthy subjects and 30 acute DVT patients. Contrast-enhanced CMR venography (CE-CMRV) was conducted for comparison and only performed in the patients...
June 25, 2018: Journal of Cardiovascular Magnetic Resonance
Ásthildur Árnadóttir, Mikkel Schoos, Jacob Lønborg, Kiril Ahtarovski, Henning Kelbæk, Steffen Helqvist, Dan Høfsten, Peter Clemmensen, Thomas Engstrøm, Lars Nepper-Christensen, Niels Vejlstrup, Lars Køber, Kasper Iversen
BACKGROUND: Primary percutaneous coronary intervention (pPCI) is recommended in patients presenting with ST-elevation myocardial infarction (STEMI) within <12 h of symptom onset. However, patients-reported symptom duration is not always reliable. Cardiac specific troponin T (cTnT) and the endogenous stress marker copeptin have different temporal release patterns for myocardial infarction MI. We hypothesized that copeptin/troponin-ratio is associated to the duration of coronary occlusion and therefore inversely proportional to myocardial salvage...
September 2018: Clinical Biochemistry
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