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CMR normal values

Sandra Pujadas, Maite Doñate, Chi-Hion Li, Soraya Merchan, Ana Cabanillas, Xavier Alomar, Guillem Pons-Llado, Ricard Serra-Grima, Francesc Carreras
There is still some controversy about the benignity of structural changes observed in athlete's heart, especially regarding the observation of increased biomarkers and the presence of myocardial fibrosis (MF). Aim: Our purpose was to evaluate by cardiovascular magnetic resonance (CMR) the presence of diffuse as well as focal MF in a series of high-performance veteran endurance athletes. Methods: Thirty-four veteran healthy male endurance athletes, still being in regular training, with more than 10 years of training underwent a CMR...
2018: BMJ Open Sport & Exercise Medicine
Elena Galli, Emilie Vitel, Frédéric Schnell, Virginie Le Rolle, Arnaud Hubert, Mathieu Lederlin, Erwan Donal
BACKGROUND: The estimation of myocardial work by pressure strain loops (PSLs) is a totally new non-invasive approach to assess myocardial performance, and its role in patients with hypertrophic cardiomyopathy is unknown. The aims of the present study are therefore: (a) to compare myocardial work in patients with non-obstructive hypertrophic cardiomyopathy (HCM) and in a subset of age-matched healthy controls and (b) to assess the correlation between myocardial work and left ventricular (LV) fibrosis...
November 29, 2018: Echocardiography
Gloria Tamborini, Claudia Cefalù, Fabrizio Celeste, Laura Fusini, Anna Garlaschè, Manuela Muratori, Sarah Ghulam Ali, Paola Gripari, Giovanni Berna, Mauro Pepi
Three-dimensional echocardiographic (3DE) of right ventricle (RV) has been validated in many clinical settings. However, the necessity of complicated and off-line dedicated software has reduced its diffusion. A new simplified "on board" 3DE software (OB) has been developed to obtain RV volumes and ejection fraction (EF) together with several conventional parameters automatically derived from 3DE: tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC), longitudinal strain (LS)...
November 15, 2018: International Journal of Cardiovascular Imaging
Sophie I Mavrogeni, Petros P Sfikakis, George Markousis-Mavrogenis, Vasiliki-Kalliopi Bournia, George Poulos, Loukia Koutsogeorgopoulou, Georgia Karabela, Efthymios Stavropoulos, Gikas Katsifis, Kyriaki Boki, Vasiliki Vartela, Genovefa Kolovou, George Theodorakis, George D Kitas
BACKGROUND: Ventricular tachycardia/fibrillation (VT/VF) may occur in autoimmune rheumatic diseases (ARDs). We hypothesized that cardiovascular magnetic resonance (CMR) can identify arrhythmogenic substrates in ARD patients. PATIENTS - METHODS: Using a 1.5 T system, we evaluated 61 consecutive patients with various types of ARDs and normal left ventricular ejection fraction (LVEF) on echocardiography. A comparison of patients with recent VT/VF and those that never experienced VT/VF was performed...
October 25, 2018: International Journal of Cardiology
Chrysanthos Grigoratos, Giancarlo Todiere, Giovanni Donato Aquaro, Andrea Barison
Cardiac palpitations secondary to ventricular ectopic beats are a frequent clinical indication for a cardiac magnetic resonance (CMR) scan. CMR has already demonstrated its additive diagnostic value in patients with frequent arrhythmias even when echocardiogram appears normal. Hereby, we describe a case of a middle-aged male patient referred to our laboratory because of frequent ventricular ectopic beats and an inconclusive echocardiogram due to an extremely poor acoustic window. A diagnosis of pericardial agenesis (PA) was made explaining patient symptoms and arrhythmias previously detected...
July 2018: Journal of Cardiovascular Echography
Olivier Ghekiere, Jurgen Bielen, Jonathon Leipsic, Willem Dewilde, Isabelle Mancini, Dominic Hansen, Paul Dendale, Alain Nchimi
Only one-third of intermediate-grade coronary artery stenosis (i.e. 40-70% diameter narrowing) causes myocardial ischemia, requiring most often additional invasive work-up with invasive fractional flow reserve (FFR). To evaluate the correlations between FFR estimates derived from computed tomography (FFRCT ) and adenosine perfusion cardiac magnetic resonance (CMR) with invasive FFR in intermediate-grade stenosis. Thirty-seven patients (mean age 61 ± 9 years; 25 men) who underwent adenosine perfusion CMR, quantitative coronary angiography and FFR in the work-up for intermediate-grade stenoses (n = 39) diagnosed at coronary CT angiography were retrospectively evaluated...
October 3, 2018: International Journal of Cardiovascular Imaging
Min Liu, Weifang Liu, Peiyao Zhang, Jing An, Guang Wang
Cardiovascular Magnetic Resonance (CMR)-based T1 mapping and Heart Deformation Analysis (CMR-HDA) can assess the myocardial tissue characteristic and strain of cardiomyopathy. Whether they can assess cardiac abnormality of hypothyroidism (HT) is unknown. We aim to analysis left ventricular (LV) T1 values and strain of patients with overt HT (OHT) and subclinical HT (SHT) with CMR-based T1 mapping and HDA. This study prospectively included 32 OHT patients, 23 SHT patients and 27 healthy controls who underwent CMR...
September 24, 2018: International Journal of Cardiovascular Imaging
Junping Peng, Xiaodan Zhao, Lei Zhao, Zhanming Fan, Zheng Wang, Hui Chen, Shuang Leng, John Allen, Ru-San Tan, Angela S Koh, Xiaohai Ma, Mingwu Lou, Liang Zhong
Reference values on atrial and ventricular strain from cardiovascular magnetic resonance (CMR) are essential in identifying patients with impaired atrial and ventricular function. However, reference values have not been established for Chinese subjects. One hundred and fifty healthy volunteers (75 Males/75 Females; 18-82 years) were recruited. All underwent CMR scans with images acceptable for further strain analysis. Subjects were stratified by age: Group 1, 18-44 years; Group 2, 45-59 years; Group 3, ≥60 years...
2018: Frontiers in Physiology
Giovanni Donato Aquaro, Fausto Pizzino, Anna Terrizzi, Scipione Carerj, Bijoy K Khandheria, Gianluca Di Bella
OBJECTIVES: We sought to evaluate the role of cardiac magnetic resonance imaging (CMR) in the evaluation of diastolic function by a combined assessment of left ventricular (LV) and left atrial (LA) function in a cohort of subjects with various degrees of diastolic dysfunction (DD) detected by echocardiography. METHODS: Forty patients with different stages of DD and 18 healthy controls underwent CMR. Short-axis cine steady-state free precession images covering the entire LA and LV were acquired...
August 20, 2018: European Radiology
Susanne Rospleszcz, Anina Schafnitzel, Wolfgang Koenig, Roberto Lorbeer, Sigrid Auweter, Cornelia Huth, Wolfgang Rathmann, Margit Heier, Birgit Linkohr, Christa Meisinger, Holger Hetterich, Fabian Bamberg, Annette Peters
BACKGROUND: Left ventricular (LV) hypertrophy and changes in LV geometry are associated with increased cardiovascular mortality. Subjects with type 2 diabetes have an increased risk of such alterations in cardiac morphology. We sought to assess the association of glycemic status and LV wall thickness measured by cardiac magnetic resonance (CMR), and potential interactions of hypertension and diabetes. METHODS: CMR was performed on 359 participants from a cross-sectional study nested in a population-based cohort (KORA FF4) free of overt cardiovascular disease...
August 9, 2018: BMC Cardiovascular Disorders
Yongning Shang, Xiaochun Zhang, Xiaoyue Zhou, Jian Wang
BACKGROUND: The extracellular volume (ECV), derived from cardiovascular magnetic resonance (CMR) T1 mapping, is a biomarker of the extracellular space in the myocardium. The hematocrit (HCT), measured from venipuncture, is required for ECV measurement. We test the clinic values of synthetic ECV, which is derived from the longitudinal relaxation of blood-based (T1blood ) synthetic hematocrit in 3 T CMR. METHODS: A total of 226 subjects with CMR T1 mapping and HCT measurement taken on the same day as the CMR were retrospectively enrolled and randomly split into derivation (n = 121) and validation (n = 105) groups, comprising healthy subjects (n = 45), type 2 diabetes mellitus (T2DM) patients (n = 60), hypertrophic cardiomyopathy (HCM) patients (n = 93), and 28 other patients...
August 9, 2018: Journal of Cardiovascular Magnetic Resonance
Clément Cholet, Thibaud Damy, François Legou, Hicham Kobeiter, Alain Rahmouni, Jean-François Deux
RATIONALE AND OBJECTIVES: Diagnosis of cardiac amyloidosis (CA) on cardiac magnetic resonance (CMR) can be challenging and quantitative indexes are relevant to further characterize the myocardium. We hypothesize that the relative myocardial enhancement measured from pre and post contrast cine imaging provides diagnostic information for CA in the setting of left ventricular hypertrophy (LVH). MATERIALS AND METHODS: Patients with LVH referred to our center and control subjects with normal CMR were retrospectively included...
July 31, 2018: Academic Radiology
Ji-Won Hwang, Min Jae Cha, Sung Mok Kim, Yiseul Kim, Yeon Hyeon Choe
The purpose of this study was to evaluate the association between myocardial deformation parameters and cardiovascular risk factors in asymptomatic Asian subjects and to provide reproducibility for deformation parameters of both ventricles using cardiovascular magnetic resonance (CMR) tissue tracking (TT). We enrolled 129 asymptomatic healthy adults who underwent CMR and assessed the cardiovascular risk factors in all individuals. All subjects had normal left ventricular systolic function. Commercial software was used to derive myocardial deformation parameters of both ventricles from short-axis cine images and long-axis cine images with two-, three-, and four-chamber views...
December 2018: International Journal of Cardiovascular Imaging
Maria Kordybach-Prokopiuk, Piotr Dobrowolski, Mirosław Kowalski, Piotr Hoffman
BACKGROUND: Restrictive physiology of right ventricle (RRVP) is a common finding in adult patients after tetralogy of Fallot (TOF) repair. In spite of many attempts to relate this phenomenon to various factors, the myocardial pathologies and clinical importance are still enigmatic. AIMS: To evaluate regional diastolic right ventricular function in patients after TOF repair with and without RRVP. METHODS: A group of 112 consecutive patients with repaired TOF underwent transthorasic echocardiography (TTE) with tissue Doppler analysis, cardiopulmonary exercise test (CPX), cardiac magnetic resonance (CMR) and laboratory test evaluation...
July 5, 2018: Kardiologia Polska
Henrik Engblom, Mikael Kanski, Sascha Kopic, David Nordlund, Christos G Xanthis, Robert Jablonowski, Einar Heiberg, Anthony H Aletras, Marcus Carlsson, Håkan Arheden
BACKGROUND: Cardiovascular magnetic resonance (CMR) can be used to calculate myocardial extracellular volume fraction (ECV) by relating the longitudinal relaxation rate in blood and myocardium before and after contrast-injection to hematocrit (Hct) in blood. Hematocrit is known to vary with body posture, which could affect the calculations of ECV. The aim of this study was to test the hypothesis that there is a significant increase in calculated ECV values if the Hct is sampled after the CMR examination in supine position compared to when the patient arrives at the MR department...
June 28, 2018: Journal of Cardiovascular Magnetic Resonance
Anna Bredfelt, Göran Rådegran, Roger Hesselstrand, Håkan Arheden, Ellen Ostenfeld
AIMS: Pre-capillary pulmonary hypertension (PHpre-cap ) has a poor prognosis, especially when caused by pulmonary arterial hypertension (PAH) associated with systemic sclerosis (SSc-PAH). Whether cardiac magnetic resonance (CMR)-based quantification of atrial volumes in PHpre-cap is beneficial in risk assessment is unknown. The aims were to investigate if (i) atrial volumes using CMR are associated with death or lung transplantation in PHpre-cap , (ii) atrial volumes differ among four unmatched major PHpre-cap subgroups, and (iii) atrial volumes differ between SSc-PAH and idiopathic/familial PAH (IPAH/FPAH) when matched for pulmonary vascular resistance (PVR)...
October 2018: ESC Heart Failure
Sophie I Mavrogeni, Flora Bacopoulou, Despoina Apostolaki, George P Chrousos
Sudden cardiac death (SCD) is the nontraumatic death, due to loss of heart function that occurs suddenly and unexpectedly within 6 hours of a previously normal state of health. It is related to intense competitive sports promoting ventricular tachycardia (VT)/ventricular fibrillation (VF) in the presence of underlying abnormal substrate. A serial evaluation of cardiac physiologic changes taking place during training will allow the better understanding of athlete's heart and will facilitate its discrimination from other grey-zone cardiomyopathies...
July 2018: European Journal of Clinical Investigation
Tarek Alsaied, Omar Niss, Adam W Powell, Robert J Fleck, James F Cnota, Clifford Chin, Punam Malik, Charles T Quinn, Michael D Taylor
BACKGROUND: Left ventricular diastolic dysfunction (DD) is an independent risk factor for mortality in sickle cell anemia (SCA) and is associated with increased extracellular volume (ECV) on cardiac MRI (CMR). Exercise impairment is common in SCA, but its causes and prognostic value are not well understood. OBJECTIVE: To study the effects of DD and ECV on cardiopulmonary exercise test (CPET) in patients with SCA. METHODS AND RESULTS: As part of a prospective study to characterize the cardiomyopathy of SCA (NCT02410811), 20 children and adults with SCA underwent CMR, echocardiography, and cycle ergometer CPET (age range 8-43 years)...
August 2018: Pediatric Blood & Cancer
Ashlee Kimball, Sanjana Patil, Bogda Koczwara, Karthigesh Sree Raman, Rebecca Perry, Suchi Grover, Joseph Selvanayagam
BACKGROUND: Anthracycline (A) and trastuzumab (T) chemotherapy have well-recognized cardiac toxicity, potentially leading to significant morbidity and mortality. Our previous work in 46 prospectively enrolled breast cancer patients showed early left ventricular (LV) and right ventricular (RV) function decline at 1 and 3 months, but only persistent RV dysfunction at 12 months which correlated with myocardial oedema observed early (1 and 3 months) after administration of chemotherapy regimes...
June 15, 2018: International Journal of Cardiology
María José Arias Téllez, Johana Patricia Soto-Sánchez, Sergio Gerardo Weisstaub
OBJECTIVE: To evaluate the association of physical fitness (PF) and cardiometabolic risk (CMR) with heart rate recovery time (ΔHRR) in Chilean school aged children. METHODS: Cross-sectional study in 478 6-9 years old children participants. We measured weight, height and abdominal circumference. Fitness was measured using the 6MWT, grip strength and leap forward without impulse tests; PF z-scores were calculated. Heart rate (HR) was monitored and recorded during the 6MWT...
January 10, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
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