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"Low Back Pain"

Jean-François Chenot
Low back pain is common, but serious underlying disorders are infrequent in ambulatory care. Extensive diagnostic testing is neither feasable nor reasonable due to epidemiological and economical considerations. A structured step wise approach allows to differentiate between specific and unspecific low back pain.
October 2018: Deutsche Medizinische Wochenschrift
Sayed A Tantawy, Walid K Abdelbasset, Dalia M Kamel, Saud M Alrawaili, Saud F Alsubaie
The purpose of this study was to compare the effects of laser photobiomodulation therapy (lPBMt) and ultrasound therapy (UST) in patients with chronic non-specific low back pain (CNLBP). Forty-five patients with CNLBP aged 30-40 years were divided randomly into three groups of 15 subjects each. The lPBMt group received 8 weeks of lPBMt with an exercise program, while the UST group received 8 weeks of UST with the same exercise program; the control group received only the exercise program for 8 weeks. Pain, disability, functional performance, and lumbar range of motion were assessed at the beginning of the study and after 8 weeks...
October 17, 2018: Lasers in Medical Science
Birgit A Greiner, Sheilah Nolan, Dervla A M Hogan
Background: Research with physical therapists reveals high rates of work-related musculoskeletal injuries, especially low back pain, with early career onset. Less focus has been given to upper limb disorder (ULD) in these professionals who are frequently performing repetitive arm/hand and precision finger motions during work. Objective: The objective was to estimate prevalence of body-site-specific upper limb (UL) symptoms and diagnosed ULD in Irish chartered physiotherapists, physical therapists, and athletic therapists, with adjustment for leisure time injury, and document first onset of specific UL symptoms...
October 17, 2018: Physical Therapy
Afshin Farhanchi, Behrouz Karkhanei, Negar Amani, Mashhood Aghajanloo, Elham Khanlarzadeh, Zahra Emami
Introduction: In this study we are aiming to evaluate the changes of serum serotonin and its association with pain in patients suffering from chronic low back pain before and after lumbar discectomy surgery. Patients and Methods: A prospective study was performed on the patients referring to the outpatient clinic in Besat hospital, Hamadan University of Medical Sciences, Hamadan, Iran, during 2016. A 2 mL fasting blood sample was collected from each patient at preoperative day 1 and postoperative day 14 and they were measured for level of serum serotonin...
2018: Pain Research and Treatment
Luigi Cardia, Gioacchino Calapai, Domenico Quattrone, Cristina Mondello, Vincenzo Arcoraci, Fabrizio Calapai, Carmen Mannucci, Epifanio Mondello
Hydrocodone is one of the most prescribed oral analgesic drugs and it is one of the most abused drugs in general population. It is a mu-opioid agonist predominantly metabolized to the O-demethylated product hydromorphone and to the N-demethylated product norhydrocodone. The purpose of the study is to summarize the preclinical and clinical characteristics of hydrocodone. Pharmacokinetic aspect (terminal half-life, maximum serum concentration, and time to maximum serum concentration) of hydrocodone and the influence of metabolic genetic polymorphism in analgesic response to hydrocodone are also illustrated and commented...
2018: Frontiers in Pharmacology
Ava Lorenc, Gene Feder, Hugh MacPherson, Paul Little, Stewart W Mercer, Deborah Sharp
OBJECTIVE: To identify potentially effective complementary approaches for musculoskeletal (MSK)-mental health (MH) comorbidity, by synthesising evidence on effectiveness, cost-effectiveness and safety from systematic reviews (SRs). DESIGN: Scoping review of SRs. METHODS: We searched literature databases, registries and reference lists, and contacted key authors and professional organisations to identify SRs of randomised controlled trials for complementary medicine for MSK or MH...
October 15, 2018: BMJ Open
Devika M Varma, Michelle S DiNicolas, Steven B Nicoll
Low back pain is a major cause for disability and is closely linked to intervertebral disc degeneration. Mechanical and biological dysfunction of the nucleus pulposus in the disc has been found to initiate intradiscal degenerative processes. Replacing or enriching the diseased nucleus pulposus with an injectable, stem cell-laden biomaterial that mimics its material properties can provide a minimally invasive strategy for biological and structural repair of the tissue. In this study, injectable, in situ-gelling carboxymethylcellulose hydrogels were developed for nucleus pulposus tissue engineering using encapsulated human marrow-derived mesenchymal stromal cells (hMSCs)...
October 2018: Journal of Biomaterials Applications
Noureddin Nakhostin Ansari, Shiva Komesh, Soofia Naghdi, Zahra Fakhari, Parisa Alaei
Study Design: A prospective, within-group cohort study of 46 patients with chronic low-back pain (CLBP). Purpose: To assess the responsiveness of the Persian Functional Rating Index (PFRI) and to determine the minimal clinically important change (MCIC) of the PFRI in a cohort of patients with CLBP. Overview of Literature: The FRI is an instrument for assessing pain and disability in patients with low-back pain. No study so far has examined the responsiveness of the PFRI...
October 18, 2018: Asian Spine Journal
Benjamin Saunders, Bernadette Bartlam, Majid Artus, Kika Konstantinou
Sciatica is a common form of low back pain (LBP) that has been identified as distinct both in terms of the persistence and severity of symptoms. Little research has explored individual experiences of sciatica, and none focuses on individuals with the most severe, long-lasting symptoms who may experience the most profound impact. This paper addresses this gap through proposing a theoretical framework for understanding such experiences, that of biographical suspension as a form of liminality of Self. Twenty semi-structured interviews were conducted with individuals with severe sciatic symptoms between January 2016‒March 2017, as part of the UK-based SCOPiC (SCiatica Outcomes in Primary Care) randomised controlled trial...
October 2, 2018: Social Science & Medicine
Erkan Erol, Ayse Yildiz, Ramazan Yildiz, Umut Apaydin, Derya Gokmen, Bulent Elbasan
STUDY DESIGN: .: Cross-cultural adaptation, and psychometric analysis OBJECTIVE..: To develop the Turkish version of the Fremantle Back Awareness Questionnaire (FreBAQ-T) and to evaluate its psychometric properties. SUMMARY OF BACKGROUND DATA: .: There is a growing interest in the role that, the disturbance of body perception may lead long lasting pain problems such as chronic low back pain (CLBP). The Fremantle Back Awareness Questionnaire (FreBAQ), is a simple and low cost way of evaluating disturbed back awareness in people with CLBP...
October 15, 2018: Spine
Guohua Shen, Minggang Su, Bin Liu, Anren Kuang
A 53-year-old man with a 10-year history of gout was admitted to our hospital due to chronic low back pain. Initial CT examinations showed a high-density mass with bone destruction of bilateral facet joints at the L3 to L5 level. MRI findings also revealed lesion with the dural sac compression. On PET/CT, the juxta-articular mass of bilateral L3 to L5 facet joints showed abnormal FDG uptake with an SUVmax of 4.2. The possible diagnosis may be gouty tophi; however, the biopsy revealed the diagnosis of calcium pyrophosphate dihydrate deposition disease, also referred to as pseudogout...
October 15, 2018: Clinical Nuclear Medicine
David S Gregory, Velyn Wu, Preyasha Tuladhar
Women often see their primary care physicians for common acute conditions during pregnancy. These conditions may be caused by pregnancy (obstetric problems) or worsened by pregnancy (obstetrically aggravated problems), or they may require special consideration during pregnancy because of maternal or fetal risks (nonobstetric problems). Primary care physicians should know the differential diagnosis for common conditions during pregnancy and recognize the important findings of obstetric and urgent nonobstetric problems...
November 1, 2018: American Family Physician
Alan M Garber, Tej D Azad, Anjali Dixit, Monica Farid, Edward Sung, Daniel Vail, Jay Bhattacharya
OBJECTIVES: Low back pain (LBP) is a common and expensive clinical problem, resulting in tens of billions of dollars of direct medical expenditures in the United States each year. Although expensive imaging tests are commonly used, they do not improve outcomes when used in the initial management of idiopathic LBP. We estimated 1-year medical costs associated with early imaging of Medicare beneficiaries with idiopathic LBP. STUDY DESIGN: We used a 5% random sample of Medicare fee-for-service enrollees between 2006 and 2010 to determine 12-month costs following a diagnosis of idiopathic LBP...
October 1, 2018: American Journal of Managed Care
Rim Maaoui, Imene Ksibi, Amani Khezami, Sonia Zrida, Nadia Chiha, Hajer Rahali
INTRODUCTION: functional restoration of the spine is a proven method in the short-term management of chronic low back pain. The aim of our study  was to evaluate the effect of a functional restoration program at two years of evolution. METHODS: retrospective study of patients enrolled in a functional restoration program during 2014 and summoned after two years,  in 2016. Patients have had the same clinical and functional evaluation before the program, at five weeks and  at two years...
January 2018: La Tunisie Médicale
Anand H Segar, Jeremy C T Fairbank, Jill Urban
PURPOSE: The aim of this study was to identify the effects of leptin upon the intervertebral disc (IVD) and to determine whether these responses are potentiated within an environment of existing degeneration. Obesity is a significant risk factor for low back pain (LBP) and IVD degeneration. Adipokines, such as leptin, are novel cytokines produced primarily by adipose tissue and have been implicated in degradative and inflammatory processes. Obese individuals are known to have higher concentrations of serum leptin, and IVD cells express leptin receptors...
October 15, 2018: European Spine Journal
H S Chhabra, Sunil Sharma, Shalini Verma
BACKGROUND: Mobile health (mHealth) is emerging as the most convenient way to deliver rehabilitation services remotely, and collect outcomes in real time, thus contributing to disease management by transferring care from hospital to home. It facilitates accessibility to healthcare, enhances patients' understanding of their condition, and their willingness to engage in self-management, giving way to high-quality care to the satisfaction of both patients and healthcare professionals. PURPOSE: The purpose of this study was to examine the effect of using a smartphone app (called Snapcare) on pain and function in patients suffering from chronic low back pain...
October 15, 2018: European Spine Journal
Wataru Kuwahara, Hiroshi Kurumadani, Nobuhiro Tanaka, Kazuyoshi Nakanishi, Haruka Nakamura, Yosuke Ishii, Akio Ueda, Masataka Deie, Nobuo Adachi, Toru Sunagawa
BACKGROUND: Lumbar alignment of posterior or anterior tilts affects the exacerbation and remission of symptoms of lumbar spinal stenosis patients. This study aimed to clarify the correlation between spinal and pelvic movements during gait and the aggravation of low back pain after gait loading in lumbar spinal stenosis patients. METHODS: A total of 29 patients with lumbar spinal stenosis completed leg and low back pain assessments and gait analysis before and after gait loading tests...
October 12, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
Morteza Dehnokhalaji, Mohammad Reza Golbakhsh, Babak Siavashi, Parham Talebian, Sina Javidmehr, Mohammadreza Bozorgmanesh
Study Design: Retrospective study. Purpose: Lumbar intervertebral disc degeneration is an important cause of low back pain. Overview of Literature: Spinal fusion is often reported to have a good course for adolescent idiopathic scoliosis (AIS). However, many studies have reported that adjacent segment degeneration is accelerated after lumbar spinal fusion. Radiography is a simple method used to evaluate the orientation of the vertebral column...
October 16, 2018: Asian Spine Journal
Erika Klassen, Karl-Ruediger Wiebelitz, André-Michael Beer
BACKGROUND: Currently, there is a need for scientific evidence on the efficacy of classical massage therapy for chronic, unspecific back pain, especially for the improvement in functional impairment and long-term pain reduction. According to the National Health Care Guidelines, classical massage for nonspecific low back pain may only be prescribed in combination with exercise therapy and a share of the remuneration. Acupuncture, on the other hand, is recognised in the guidelines as an independent treatment for chronic back pain and is remunerated by health insurance companies...
October 15, 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
Ali Yeganeh, Mehdi Moghtadaei, Mohsen Motalebi
Background: Adult degenerative disorders of hip and spine are common. The recent studies inconsistently have discussed about the influence of spinal disorders on total hip arthroplasty (THA). In this review, we discussed clearly about these relationships and their effects on the most appropriate position of the acetabular component. Methods: We searched on databases and evaluated the articles about spinopelvic parameters in patients with spinal disorders who needed THA...
September 2018: Archives of Bone and Joint Surgery
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