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Pulmonary embolism heparin

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https://www.readbyqxmd.com/read/30316671/-venous-thromboembolism-and-urological-cancer-epidemiology-and-therapeutically-management
#1
M Felber, F Rozet, S Droupy, V Misraï, D M Smadja, M Rouprêt
INTRODUCTION: Active cancer is a risk factor in the occurrence of venous thromboembolism (VTE). This is the second cause of death for these patients. In onco-urology, some cancers are associated with an increased risk of VTE. The aim of this study was to propose a focus of epidemiology and VTE therapy management. MATERIAL AND METHODS: A systematic analysis of the PubMed® database was performed through the PRISMA methodology using the followings keywords : "neoplasm", "venous thromboembolism", "prophylaxis", "pulmonary embolism", "urology"...
October 10, 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/30309428/-clinical-value-evaluation-of-perioperative-prophylactic-anticoagulation-therapy-for-lung-cancer-patients
#2
Hui Xu, Hu Liao, Guowei Che, Kun Zhou, Mei Yang, Lunxu Liu
BACKGROUND: The incidence of pulmonary embolism (PE) in lung cancer patients who underwent surgery increased during the perioperative period, and prophylactic anticoagulation therapy was important part of enhanced recovery after surgery (ERAS). However, the timing of preventive anticoagulation in patients with lung cancer remained controversial. This study was designed to investigate the safety and efficacy of perioperative prophylactic anticoagulation therapy for lung cancer patients...
October 20, 2018: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/30298364/prevention-of-venous-thrombosis-after-electrophysiology-procedures-a-survey-of-national-practice
#3
Barry Burstein, Rodrigo S Barbosa, Michelle Samuel, Eli Kalfon, François Philippon, David Birnie, Iqwal Mangat, Damian Redfearn, Roopinder Sandhu, Laurent Macle, John Sapp, Atul Verma, Jeff S Healey, Giuliano Becker, Vijay Chauhan, Benoit Coutu, Jean-François Roux, Peter Leong-Sit, Jason G Andrade, George D Veenhuyzen, Jacqueline Joza, Martin Bernier, Vidal Essebag
PURPOSE: Femoral venous access is required for most electrophysiology procedures. Limited data are available regarding post-procedure venous thromboembolism (VTE), specifically deep vein thrombosis (DVT) and pulmonary embolism (PE). Potential preventative strategies are unclear. We aimed to survey Canadian centers regarding incidence of VTE and strategies for prevention of VTE after procedures that do not require post-procedure anticoagulation. METHODS: An online survey was distributed to electrophysiologists representing major Canadian EP centers...
October 8, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/30292445/-management-and-prognosis-of-pulmonary-embolism-associated-with-right-heart-thrombi-a-prospective-study-at-the-university-hospital-yalgado-ou%C3%A3-draogo
#4
T A A Seghda, N V Yaméogo, G R C Millogo, L Kagambega, J Kologo, T Boro, A Samadoulougou, P Zabsonré
OBJECTIVE: To describe the management and evolution of high risk of death pulmonary embolism associated with right heart thrombi. MATERIAL AND METHODS: We conducted a prospective cohort survey over a 54 month-period, from March 1st, 2012 to September 30th 2015. Were included all patients with pulmonary embolism and having high or intermediate-high risk of death. Patients were divided into two groups according to whether cardiac Doppler-echography found a thrombus in the right chambers or not (ICT+ vs...
October 3, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/30288849/post-ablation-cerebral-embolisms-in-balloon-based-atrial-fibrillation-ablation-with-periprocedural-direct-oral-anticoagulants-a-comparison-between-cryoballoon-and-hotballoon-ablation
#5
Kohki Nakamura, Takehito Sasaki, Yutaka Take, Yoshinori Okazaki, Mitsuho Inoue, Hiroyuki Motoda, Yuko Miki, Katsura Niijima, Eiji Yamashita, Keiko Koyama, Nobusada Funabashi, Shigeto Naito
INTRODUCTION: This prospective observational study aimed to investigate the incidence of symptomatic and silent cerebral embolisms after balloon-based ablation of atrial fibrillation (AF) in patients receiving periprocedural anticoagulation with direct oral anticoagulants (DOACs), and compare that between cryoballoon and HotBalloon ablation (CBA and HBA). METHODS AND RESULTS: We enrolled 123 consecutive AF patients who underwent a balloon-based pulmonary vein isolation (PVI) and brain magnetic resonance (MR) imaging after the ablation procedure (CBA, n=65; HBA, n=58)...
October 4, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/30279820/successful-treatment-of-a-massive-pulmonary-embolism-using-rivaroxaban-in-a-patient-with-antithrombin-iii-deficiency
#6
Junji Yamaguchi, Nobuhiro Hara, Tetsuo Yamaguchi, Yasutoshi Nagata, Toshihiro Nozato, Takamichi Miyamoto
We report a case of acute massive pulmonary embolism in a patient with antithrombin III deficiency. The patient was treated with rivaroxaban. The patient responded well to the therapy, and contrast-enhanced computed tomography showed nearly complete disappearance of the pulmonary embolism. Patients with low antithrombin III activity may have resistance to heparin therapy, leading to insufficient anticoagulation during the acute phase of thromboembolism. This case suggests that direct oral anticoagulants, such as rivaroxaban, may be effective first-line agents for treating venous thromboembolism in patients with antithrombin III deficiency...
November 2017: Journal of Cardiology Cases
https://www.readbyqxmd.com/read/30276659/position-paper-of-the-italian-society-of-internal-medicine-simi-on-prophylaxis-and-treatment-of-venous-thromboembolism-in-patients-with-cancer
#7
REVIEW
Domenico Prisco, Antonella Tufano, Caterina Cenci, Pasquale Pignatelli, Francesca Santilli, Giovanni Di Minno, Francesco Perticone
Cancer patients are at high risk of developing thrombotic events, including venous thromboembolism (VTE) [deep venous thrombosis (DVT) and pulmonary embolism (PE)], and arterial thrombosis. DVT and PE represent the second leading cause of death in cancer patients; moreover, the development of thromboembolic events in cancer patients is linked to a greater need of hospitalization and frequency of side effects during treatment, in particular bleeding, and to an increased risk of recurrence during and following antithrombotic therapy...
October 1, 2018: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/30210627/lung-cancer-and-pulmonary-embolism-what-is-the-relationship-a-review
#8
REVIEW
Yupeng Li, Yu Shang, Wenwen Wang, Shangwei Ning, Hong Chen
Pulmonary embolism (PE) is gradually considered to be the third most common disease in the vascular disease category. Lung cancer is the most frequently diagnosed cancer and the leading cause of cancer death among males worldwide. Although initially appearing as distinct entities, lung cancer is a great risk factor for the development of PE. Pulmonary embolism is common in lung cancer patients, with a pooled incidence of 3.7%, and unsuspected pulmonary embolism (UPE) is also non-negligible with a rough rate ranging from 29...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/30199784/pulmonary-embolism-in-europe-burden-of-illness-in-relationship-to-healthcare-resource-utilization-and-return-to-work
#9
Stefan N Willich, Ling-Hsiang Chuang, Ben van Hout, Pearl Gumbs, David Jimenez, Sonja Kroep, Rupert Bauersachs, Manuel Monreal, Giancarlo Agnelli, Alexander Cohen
OBJECTIVES: Pulmonary embolism (PE) is associated with a substantial economic burden. However evidence from patients in Europe is scarce. The aim of this study was to report the impacts of PE on healthcare resource utilization (HCRU) and return to work using the PREFER in VTE registry. METHODS: The PREFER in VTE registry was a prospective, observational, multicenter study in seven European countries, aiming to provide data concerning treatment patterns, HCRU, mortality, quality of life and work-loss...
October 2018: Thrombosis Research
https://www.readbyqxmd.com/read/30193575/low-molecular-weight-heparin-versus-other-anti-thrombotic-agents-for-prevention-of-venous-thromboembolic-events-after-total-hip-or-total-knee-replacement-surgery-a-systematic-review-and-meta-analysis
#10
Xin Lu, Jin Lin
BACKGROUND: Venous thromboembolism (VTE) is an important complication following total hip replacement (THR) and total knee replacement (TKR) surgeries. Aim of this study was to comprehensively compare the clinical outcomes of low-molecular-weight heparin (LMWH) with other anticoagulants in patients who underwent TKR or THR surgery. METHODS: Medline, Cochrane, EMBASE, and Google Scholar databases were searched for eligible randomized controlled studies (RCTs) published before June 30, 2017...
September 8, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/30190110/extended-versus-conventional-thromboprophylaxis-after-major-abdominal-and-pelvic-surgery-systematic-review-and-meta-analysis-of-randomized-clinical-trials
#11
Emanuele Rausa, Michael E Kelly, Emanuele Asti, Alberto Aiolfi, Gianluca Bonitta, Desmond C Winter, Luigi Bonavina
BACKGROUND: Venous thromboembolism, presenting as deep vein thrombosis or pulmonary embolism, can be associated with considerable morbidity after major abdominal and pelvic surgery. Perioperative thromboprophylaxis with low-molecular-weight heparin is well established, but the duration of treatment remains debated. We aimed to assess the efficacy and safety of extended (4-week) versus conventional (1-week) thromboprophylaxis with low-molecular-weight heparin in patients undergoing abdominopelvic surgery...
September 3, 2018: Surgery
https://www.readbyqxmd.com/read/30189059/prevention-of-deep-venous-thromboembolism
#12
Daniel J Grabo, Jason M Seery, Matthew Bradley, Scott Zakaluzny, Michel J Kearns, Nathanial Fernandez, Matthew Tadlock
The nature of many combat wounds puts patients at a high risk of developing deep venous thrombosis (DVT) and pulmonary embolism (PE), which fall under the broader disease category of venous thromboembolism (VTE). In addition to the hypercoagulable state induced by trauma, massive injuries to the extremities, prolonged immobility, and long fixed wing transport times to higher echelons of care are unique risk factors for venous thromboembolism in the combat-injured patient. These risk factors mandate aggressive prophylaxis for DVT and PE that can effectively be achieved by the use of lower extremity sequential compression devices and low dose unfractionated heparin or low molecular weight heparin...
September 1, 2018: Military Medicine
https://www.readbyqxmd.com/read/30169381/early-massive-pulmonary-embolism-after-total-hip-arthroplasty-in-a-patient-with-behcet-disease-a-case-report
#13
Charlotte Martin, Jonathan Au Duong, Bernard Tissot, Vincent Minville, Fabrice Ferré
Venous complications in Behcet disease (BD) affect nearly 40% of patients. We describe a woman with BD who presented with a massive bilateral pulmonary embolism 30 hours after total hip arthroplasty. The patient underwent surgical thrombectomy and venoarterial extracorporeal membrane oxygenation. Methotrexate was withheld 15 days before surgery and restarted on postoperative day 2. Immunosuppressive therapy, such as methotrexate, appears to be the most effective prophylactic treatment for venous thrombosis in patients with BD, whereas prophylaxis with low-molecular-weight heparin may be ineffective, as was the situation in our patient...
August 29, 2018: A&A practice
https://www.readbyqxmd.com/read/30157593/rivaroxaban-and-acetylsalicylic-acid-for-prevention-of-venous-thromboembolism-following-total-knee-arthroplasty-in-korean-patients
#14
Kyu Sung Chung, Tae Yang Shin, Sang Hoon Park, Hyuck Kim, Choong Hyeok Choi
Purpose: To investigate the incidence of venous thromboembolism (VTE) after total knee arthroplasty (TKA) with chemoprophylaxis using acetylsalicylic acid (AA) or rivaroxaban in Korean patients. Materials and Methods: Between May 2011 and November 2013, 268 TKA patients (330 cases) were randomly allocated to 3 groups (group A: subcutaneous injection of 5,000 IU low-molecular-weight heparin for 2 days followed by oral administration of 100 mg AA for 5 days; group X7: oral administration of 10mg rivaroxaban for 7 days; and group X10: oral administration of 10 mg rivaroxaban for 10 days)...
September 1, 2018: Knee Surgery & related Research
https://www.readbyqxmd.com/read/30122173/prevention-of-deep-vein-thrombosis-and-pulmonary-embolism-in-high-risk-medical-patients
#15
REVIEW
Megan McCullough, Cyrus Kholdani, Roham T Zamanian
Venous thromboembolism accounts for significant morbidity and mortality in patients with acute medical illnesses requiring hospital admission. American College of Chest Physicians guidelines recommend prophylaxis with heparins as first line and mechanical methods as second line. The risk of major bleeding with anticoagulants is less than 1% and not significantly different between agents. Although data support the use of all heparins, there is a trend toward superiority of low-molecular-weight heparins (LMWHs)...
September 2018: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/30103252/apixaban-versus-dalteparin-for-the-treatment-of-acute-venous-thromboembolism-in-patients-with-cancer-the-caravaggio-study
#16
Giancarlo Agnelli, Cecilia Becattini, Rupert Bauersachs, Benjamin Brenner, Mauro Campanini, Alexander Cohen, Jean Marie Connors, Andrea Fontanella, Gualberto Gussoni, Menno V Huisman, Catherine Lambert, Guy Meyer, Andres Muñoz, Joaquim Abreu de Sousa, Adam Torbicki, Melina Verso, Giorgio Vescovo
International and national guidelines recommend low-molecular-weight heparin for the treatment of venous thromboembolism (VTE) in patients with cancer. The aim of the Caravaggio study is to assess whether oral apixaban is non-inferior to subcutaneous dalteparin for the treatment of acute proximal deep vein thrombosis and/or pulmonary embolism in patients with cancer. The study is an investigator-initiated, multi-national, prospective, randomized, open-label with blind end-point evaluation (PROBE), non-inferiority clinical trial (NCT03045406)...
September 2018: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/30086679/corrigendum
#17
(no author information available yet)
Alzghari SK, Seago SE, Garza JE, Hashimie YF, Baty KA, Evans MF, Shaver C and Herrington JD (2017). Retrospective comparison of low molecular weight heparin vs. warfarin vs. oral Xa inhibitors for the prevention of recurrent venous thromboembolism in oncology patients: The Re-CLOT study. Journal of Oncology Pharmacy Practice, published online July 2017. (Original DOI 10.1177/1078155217718382 ). In the above referenced article, sentence 2, line 3 on page 4 should read: One patient presented with a recurrent pulmonary embolism (PE) in the enoxaparin cohort (4...
August 7, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/30077602/thrombus-reformation-in-the-pulmonary-vein-stump-confirmed-16-months-after-cerebral-embolism-on-the-day-after-left-upper-lobectomy-for-lung-cancer
#18
Genki Usui, Jun Matsumoto, Hirotsugu Hashimoto, Takehiro Katano, Masashi Kusakabe, Hajime Horiuchi, Seiji Okubo
Cerebral embolism is a very serious complication after lung cancer surgery. In such cases, cerebral embolism is caused by a thrombus formed in the pulmonary vein stump. Most such cases have been reported to occur within 10 days after left upper lobectomy. The patients were treated with anticoagulation therapy to prevent the recurrence of cerebral embolism, and recurrence or thrombus reformation has not been reported to the best of our knowledge. We present a 68-year-old man with a cerebral embolism detected on the day after left upper pulmonary lobectomy for lung cancer...
October 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30056293/the-efficacy-and-safety-of-anticoagulation-in-cerebral-vein-thrombosis-a-systematic-review-and-meta-analysis
#19
Bader Al Rawahi, Mosaad Almegren, Marc Carrier
BACKGROUND: Anticoagulation with unfractionated heparin (UFH) or low molecular weight heparin (LMWH) is the mainstay for the treatment of patients with acute cerebral vein thrombosis (CVT) with or without intracranial hemorrhage (ICH). AIM: We conducted a systematic review and meta-analysis to determine the efficacy and safety of LMWH compared to UFH for the treatment of acute CVT. METHODS: An electronic search of MEDLINE, Pubmed, CENTRAL and Google Scholar was performed...
September 2018: Thrombosis Research
https://www.readbyqxmd.com/read/30045793/-risk-of-anticoagulation-therapy-in-surgical-intensive-care-unit-patients-predicted-by-thromboelastograph
#20
Zixia Wu, Zhiyong Liu, Wei Zhang, Wenzheng Zhang, En Mu
OBJECTIVE: To explore the correlation between thromboelastography (TEG) parameters and the risk of venous thromboembolism (VTE) and bleeding in patients receiving anticoagulant therapy in surgical intensive care unit (SICU). METHODS: 205 patients received low molecular weight heparin (LMWH) anticoagulant therapy admitted to SICU of Tianjin Hospital from December 2016 to December 2017 were consecutively enrolled. TEG detection was performed in all patients at 1 day after anticoagulation therapy, and coagulation reaction time (R value), blood clot generation time (K value), blood clot generation rate (α angle) and maximum width value (MA value) were recorded...
July 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
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