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https://www.readbyqxmd.com/read/30341918/how-the-cioms-guidelines-contribute-to-fair-inclusion-of-pregnant-women-in-research
#1
Rieke van der Graaf, Indira S E van der Zande, Johannes J M van Delden
As early as 2002, CIOMS stated that pregnant women should be presumed eligible for participation in research. Despite this position and calls of other well-recognized organizations, the health needs of pregnant women in research remain grossly under-researched. Although the presumption of eligibility remains unchanged, the revision of the 2002 CIOMS International ethical guidelines for biomedical research involving human subjects involved a substantive rewrite of the guidance on research with pregnant women and related guidelines, such as those on fair inclusion and vulnerability...
October 20, 2018: Bioethics
https://www.readbyqxmd.com/read/30341498/systematic-literature-review-of-the-methodology-for-developing-pharmacotherapeutic-interchange-guidelines-and-their-implementation-in-hospitals-and-ambulatory-care-settings
#2
REVIEW
Maria Adrover-Rigo, Maria-Dolores Fraga-Fuentes, Francesc Puigventos-Latorre, Iciar Martinez-Lopez
PURPOSE: To summarize literature specific to therapeutic interchange (TI) focusing on methodological approaches in order to develop a list of steps that healthcare facilities can consult when developing pharmacotherapeutic interchange guidelines (PTIGs) in hospitals and primary care centers. METHODS: A search was conducted in PreMEDLINE, Medline, EMBASE, PsycINFO, and the Cochrane Library up to and including December 2015. PRISMA guidelines were used. The inclusion criteria were articles published on TI: methodology, implementation, guidelines, and position statements of scientific societies...
October 19, 2018: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/30341445/-management-of-syncope-in-clinical-practice-what-has-changed-according-to-the-new-esc-guidelines-2018
#3
S Oebel, G Hindricks
Syncope is a common problem in clinical practice, which affects approximately 1% of patients admitted to European emergency departments. The clinical practice guidelines for the diagnosis and management of syncope published by the European Society of Cardiology (ESC) are based on the newest scientific data in the field and have provided clinical cardiologists with a structured therapeutic approach for affected patients over many years. The previous ESC guidelines on syncope were published in 2009 and are compared to the most recent edition, which was published in 2018...
October 19, 2018: Herz
https://www.readbyqxmd.com/read/30340754/american-gastroenterological-association-institute-guideline-on-the-medical-management-of-opioid-induced-constipation
#4
Seth D Crockett, Katarina B Greer, Joel J Heidelbaugh, Yngve Falck-Ytter, Brian J Hanson, Shahnaz Sultan
No abstract text is available yet for this article.
October 16, 2018: Gastroenterology
https://www.readbyqxmd.com/read/30340246/implementation-of-fetal-cardiac-guidelines-for-the-routine-second-trimester-heart-examination-a-feasibility-study
#5
Angeliki Gerede, Alexandros Sotiriadis, Aikaterini Karavida, Stamatios Petousis, Themistoklis Mikos, Efstratios Assimakopoulos, Basil C Tarlatzis, Apostolos P Athanasiadis
PURPOSE:  This study aimed to explore the feasibility of implementation of the ISUOG 2013 guidelines on routine second-trimester examination of the fetal heart. MATERIALS AND METHODS:  This was a prospective study in 357 women with singleton pregnancy undergoing their routine second-trimester scan. The fetal heart was examined using B-mode in different planes according to the guidelines. Potential maternal and fetal factors that can affect the rates of diagnostic-quality imaging for each of the recommended views were tested, using regression analysis...
October 19, 2018: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/30339738/scientific-evidence-on-functional-food-and-its-commercial-communication-a-review-of-legislation-in-europe-and-the-usa
#6
REVIEW
Cristina González-Díaz, Diana Gil-González, Carlos Álvarez-Dardet
This study aims at understanding how scientific evidence to substantiate nutrition and health claims in food commercial communication is regulated in Europe and the USA. A literature review was performed on the scientific evidence required by the European Food Safety Authority and the US Food and Drug Administration to substantiate food nutrition and health claims. Studies published in Scopus, Medline, Scirus, and Google Scholar from 2007 to 2012 were reviewed as well as documents released by both agencies...
October 19, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/30336680/a-retrospective-chart-review-of-transfusion-practices-in-the-palliative-care-unit-setting
#7
Giovanna Sirianni, Giulia Perri, Jeannie Callum, Sandra Gardner, Anna Berall, Debbie Selby
BACKGROUND: There remains limited data in the literature on the frequency, clinical utility and effectiveness of transfusions in palliative care, with no randomized controlled trials or clinical practice guidelines on this topic. There are no routinely accepted practices in place for the appropriate transfusion of blood products in this setting. AIM: The aim of this study was to retrospectively review all transfusions in the palliative care units of 2, tertiary care hospitals in Canada...
October 18, 2018: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/30336211/reporting-guidelines-on-how-to-write-a-complete-and-transparent-abstract-for-overviews-of-systematic-reviews-of-health-care-interventions
#8
Konstantinos I Bougioukas, Emmanouil Bouras, Fani Apostolidou-Kiouti, Stamatia Kokkali, Malamatenia Arvanitidou, Anna-Bettina Haidich
OBJECTIVE: An overview of systematic reviews (OoSRs) is a study designed to offer a broad view of evidence from existing systematic reviews (SRs). The abstract is an important part of an OoSRs as it can determine whether reading the full text is of interest. The aim of this paper is to offer guidelines to promote transparent and sufficient reporting in abstracts of OoSRs of health care interventions. STUDY DESIGN AND SETTING: The items were developed by combining key features from abstracts of OoSRs, PRISMA for abstracts and our published reporting guidelines for OoSRs...
October 15, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/30335637/evidence-based-physiatry-the-cdc-guideline-on-pediatric-mild-traumatic-brain-injury-and-the-expanded-role-of-physiatry
#9
Mary Alexis Iaccarino, Sabrina Paganoni, Ross Zafonte
No abstract text is available yet for this article.
October 16, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/30334936/cognitive-aids-for-the-diagnosis-and-treatment-of-neuroanesthetic-emergencies-consensus-guidelines-on-behalf-of-the-society-for-neuroscience-in-anesthesiology-and-critical-care-snacc-education-committee
#10
Amie L Hoefnagel, Shobana Rajan, Adriana Martin, Vibha Mahendra, Amanda K Knutson, Jamie L Uejima, Guy Kositratna, Mark Weller, Hui Yang, Sanchit Ahuja, Caryl Bailey, John F Bebawy
Cognitive aids and evidence-based checklists are frequently utilized in complex situations across many disciplines and sectors. The purpose of such aids is not simply to provide instruction so as to fulfill a task, but rather to ensure that all contingencies related to the emergency are considered and accounted for and that the task at hand is completed fully, despite possible distractions. Furthermore, utilization of a checklist enhances communication to all team members by allowing all stakeholders to know and understand exactly what is occurring, what has been accomplished, and what remains to be done...
October 16, 2018: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/30334656/adolescents-reasons-to-unfriend-on-facebook
#11
Karen Verswijvel, Wannes Heirman, Kris Hardies, Michel Walrave
This study is the first to examine adolescents' reasons for unfriending people on Facebook. By means of open-end questions, 419 participants described the primary online (i.e., arising from friends' behavior on Facebook) or offline (i.e., emerging from Facebook friends' offline behavior) reason for which they recently unfriended someone. Two researchers took part in the coding process. Qualitative analyses revealed that unfriending happened mainly for online reasons, such as posting (too much) inappropriate, polarizing, or uninteresting posts; seeking attention, bragging, or stalking; and other irritating behaviors (e...
October 2018: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/30334625/the-infant-with-severe-bronchiolitis-from-hfnc-to-cpap-and-mechanical-ventilation
#12
Andrea Wolfler, Gianfranco Raimondi, Cecilia Pagan de Paganis, Elena Zoia
INTRODUCTION: Bronchiolitis is one of the most frequent reasons for PICU admission in children less than 1 year of age. It causes a wide spectrum of clinical scenarios from mild to severe respiratory failure and supportive therapy range from HFNC to nonconventional ventilation and ECMO in the most severe forms. Aim of this article is to review the available ventilation mode in children with bronchiolitis and the scientific evidence. EVIDENCE ACQUISITION: The main medical databases were explored to search for clinical trials that address management strategies for respiratory support of infants with RSV infection...
October 18, 2018: Minerva Pediatrica
https://www.readbyqxmd.com/read/30334528/antimyoclonic-effect-of-levetiracetam-and-clonazepam-combined-treatment-on-myoclonic-epilepsy-with-ragged-red-fiber-syndrome-with-m-8344a-g-mutation
#13
Li-Jun Su, Yu-Liang Wang, Tao Han, Shan Qiao, Ke-Jun Zang, Huai-Kuan Wu, Yong-Xin Su, Ling-Ling Liu, Xue-Wu Liu
Background: Treatment of myoclonic seizures in myoclonic epilepsy with ragged-red fibers (MERRFs) has been empirical and ineffective. Guideline on this disease is not available. Additional trials must be conducted to find more suitable treatments for it. In this study, the antimyoclonic effects of monotherapies, including levetiracetam (LEV), clonazepam (CZP), valproic acid (VPA), and topiramate (TPM) compared to combination therapy group with LEV and CZP on MERRF, were evaluated to find a more advantageous approach on the treatment of myoclonic seizures...
October 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/30332601/canadian-urological-association-guideline-on-male-lower-urinary-tract-symptoms-benign-prostatic-hyperplasia-mluts-bph-2018-update
#14
J Curtis Nickel, Lorne Aaron, Jack Barkin, Dean Elterman, Mahmoud Nachabé, Kevin C Zorn
No abstract text is available yet for this article.
October 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/30328092/kidney-transplantation-in-patients-with-previous-renal-cancer-a-critical-appraisal-of-current-evidence-and-guidelines
#15
REVIEW
Giovanni M Frascà, Fabiana Brigante, Alessandro Volpe, Laura Cosmai, Maurizio Gallieni, Camillo Porta
Due to the increasing occurrence of renal cell carcinoma (RCC) in the general population and the high prevalence of chronic kidney disease among cancer patients, many people with a previous RCC may eventually require renal replacement therapy including kidney transplantation. They should accordingly be evaluated to assess their life expectancy and the risk that the chronic immunosuppressive therapy needed after grafting might impair their long-term outcome. Current guidelines on listing patients for renal transplantation suggest that no delay is required for subjects with small or incidentally discovered RCC, while the recommendations for patients who have been treated for a symptomatic RCC or for those with large or invasive tumours are conflicting...
October 16, 2018: Journal of Nephrology
https://www.readbyqxmd.com/read/30327867/long-term-opioid-therapy-of-non-cancer-pain-prevalence-and-predictors-of-hospitalization-in-the-event-of-possible-misuse
#16
W Häuser, T Schubert, N Scherbaum, T Tölle
BACKGROUND: One major concern of long-term opioid therapy (LTOT) for chronic noncancer pain (CNCP) is the risk of abuse of prescribed opioids. OBJECTIVE: To examine the prevalence and predictors of opioid use-related hospitalizations and potential abuse of prescribed opioids by persons with LTOT for CNCP in a sample representative of the German statutory health insurance companies. METHODS: Retrospective cross-sectional study in 2014. Anonymized German health claims database, including 4,028,618 insured individuals of 69 German statutory health insurances...
October 16, 2018: Der Schmerz
https://www.readbyqxmd.com/read/30327406/protocol-for-a-multicentre-dual-prospective-and-retrospective-cohort-study-investigating-timing-of-ileostomy-closure-after-anterior-resection-for-rectal-cancer-the-closure-of-ileostomy-timing-close-it-study
#17
Peter G Vaughan-Shaw, Katherine Gash, Katie Adams, Abigail E Vallance, Sophie A Pilkington, Jared Torkington, Julie A Cornish
INTRODUCTION: A defunctioning ileostomy is often formed during rectal cancer surgery to reduce the potentially fatal sequelae of anastomotic leak. Once the ileostomy is closed and bowel continuity restored, many patients can suffer poor bowel function, that is, low anterior resection syndrome (LARS). It has been suggested that delay to closure can increase incidence of LARS which is known to significantly reduce quality of life. Despite this, within the UK, time to closure of ileostomy is not subject to national targets within the National Health Service and delay to closure exceeds 18 months in one-third of patients...
October 15, 2018: BMJ Open
https://www.readbyqxmd.com/read/30327293/ashp-guidelines-on-handling-hazardous-drugs
#18
Luci A Power, Joseph W Coyne
No abstract text is available yet for this article.
October 16, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/30325855/accelerating-the-drug-delivery-pipeline-for-acute-and-chronic-pancreatitis-knowledge-gaps-and-research-opportunities-overview-summary-of-a-national-institute-of-diabetes-and-digestive-and-kidney-diseases-workshop
#19
Aliye Uc, Dana K Andersen, Drucy Borowitz, Marshall J Glesby, Julia Mayerle, Robert Sutton, Stephen J Pandol
A workshop was sponsored by the Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, on July 25, 2018, in Pittsburgh, Penn. The workshop was designed to bring together a multidisciplinary group of experts to accelerate the development of therapeutics for clinical application in inflammatory diseases of the exocrine pancreas. Three separate working groups (acute pancreatitis, recurrent acute pancreatitis, and chronic pancreatitis) were formed to address the needs, gaps, and opportunities...
November 2018: Pancreas
https://www.readbyqxmd.com/read/30324778/urgent-laparotomy-in-patients-with-metastatic-colorectal-cancer-presenting-as-an-acute-abdomen-a-retrospective-analysis
#20
Sami Gendler, Hila Shmilovich, David Aranovich, Roy Nadler, Hanoch Kashtan, Michael Stein
BACKGROUND: Unlike the elective treatment of metastatic colorectal cancer (MCRC), sufficient data and consensual guidelines on acute care are lacking. OBJECTIVES: To analyze a cohort of MCRC patients who required urgent surgery due to acute abdomen and to identify risk factors contributing to the patient's perioperative mortality and morbidity. METHODS: A retrospective analysis was conducted of patients diagnosed with stage IV colorectal cancer who required urgent laparotomy at the Rabin Medical Center...
October 2018: Israel Medical Association Journal: IMAJ
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