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M Margariti, M Hadjulis, M Lazaridou, G F Angelidis, V Fotopoulos, L Markaki, F Koulouri
Schizophrenia is one of the most disabling disorders globally, with a significant impact on the professional, social and personal functioning of those affected. Mortality rates are estimated to be 2-2.5 times greater than in the general population attributable to not only suicide but also physical illnesses, such as cardiovascular, metabolic and infectious diseases. Patients with schizophrenia have increased needs for health services which vary according to the stage of the illness and the way the disorder affects the patient...
April 2018: Psychiatrikē, Psychiatriki
Alexander Procaskey, Heather White, Tregony Simoneau, Nadav Traeger, Thomas Lahiri, Elie Abu Jawdeh, Ted Kremer, Catherine Sheils, Kathleen Meyer, Ted Rosenkrantz, Krishnan Sankaran, Tyler Hartman, Henry Feldman, Lawrence Rhein
Improved survival among preterm infants has led to an increase in diagnosis of chronic lung disease and infants discharged home from the NICU on supplemental oxygen. Despite this increased prevalence, no clearly defined guidelines for the management of home oxygen therapy (HOT) exist. This lack of consensus leads to significant variability in the duration of home oxygen therapy and a general paucity of evidence-based practice. Our team has identified recorded home oxygen therapy (RHO) as a potential new resource to guide clinical decision making in the outpatient pulmonology clinic...
August 11, 2018: Contemporary Clinical Trials
Yoko Edahiro, Jun Ando, Toshifumi Suzuki, Yuki Fukumura, Azuchi Masuda, Shiori Sakayori, Jun Takeda, Yojiro Maruyama, Shintaro Makino, Atsuo Itakura, Norio Komatsu
Myeloproliferative neoplasms (MPNs), including polycythemia vera, essential thrombocythemia (ET), and primary myelofibrosis, mainly occur in older patients, but have also been reported in younger patients. A "second peak" occurs in female patients in their thirties, particularly in ET; thus, the management of pregnancy is often discussed. We herein present the case of a 33-year-old woman with a high platelet count and multiple placental infarcts during delivery who was subsequently diagnosed with ET...
August 10, 2018: Internal Medicine
Lorenzo Rinaldo, Diane M Johnson, Roanna L Vine, Alejandro A Rabinstein, Giuseppe Lanzino
OBJECTIVE Clinical trials forming the basis of current guidelines for the management of intracranial aneurysms have relied on patient-reported modified Rankin Scale (mRS) scores to assess functional outcome. The effect of patient demographics on perception of disability and, by extension, patient-reported mRS score, is not well understood. METHODS A consecutive series of patients with a previously treated or untreated unruptured intracranial aneurysm (UIA) prospectively underwent a structured interview with a trained nurse...
August 10, 2018: Journal of Neurosurgery
Aila Nica Bandong, Andrew Leaver, Martin Mackey, Rodney Ingram, Samantha Shearman, Christen Chan, Ian D Cameron, Niamh Moloney, Rebecca Mitchell, Eoin Doyle, Emma Leyten, Trudy Rebbeck
BACKGROUND: In Australia, the New South Wales (NSW) State Insurance Regulatory Authority has been continuously developing and implementing clinical practice guidelines to address the health and economic burden from whiplash associated disorders (WAD). Despite this, it is uncertain the extent to which the guidelines are followed. This study aimed to determine insurer and health professional compliance with recommendations of the 2014 NSW clinical practice guidelines for the management of acute WAD; and explore factors related to adherence...
August 8, 2018: BMC Health Services Research
Linus Chuang
No abstract text is available yet for this article.
July 2018: Journal of Global Oncology
Supriya J Chopra, Ashwathy Mathew, Amita Maheshwari, Neerja Bhatla, Shalini Singh, Bhawana Rai, Shylasree T Surappa, Jaya Ghosh, Dayanand Sharma, Jaydip Bhaumik, Manash Biswas, Kedar Deodhar, Palak Popat, Sushil Giri, Umesh Mahantshetty, Hemant Tongaonkar, Ramesh Billimaga, Reena Engineer, Surbhi Grover, Abraham Pedicayil, Jyoti Bajpai, Bharat Rekhi, Aruna Alihari, Govind Babu, Rajkumar Thangrajan, Santosh Menon, Sneha Shah, Sidhanna Palled, Yogesh Kulkarni, Seema Gulia, Lavanya Naidu, Meenakshi Thakur, Venkatesh Rangrajan, Rajendra Kerkar, Sudeep Gupta, Shyam K Shrivastava
Standard guidelines for the management of early and locally advanced cervical cancer are available from various academic consortiums nationally and internationally. However, implementing standard-of-care treatment poses unique challenges within low- and middle-income countries, such as India, where diverse clinical care practices may exist. The National Cancer Grid, a consortium of 108 institutions in India, aims to homogenize care for patients with cervical cancer by achieving consensus on not only imaging and management, but also in addressing potential solutions to prevalent challenges that affect the homogenous implementation of standard-of-care treatment...
July 2018: Journal of Global Oncology
Jenifer Barrie, Saurabh Jamdar, Neil Smith, Simon J McPherson, Ajith K Siriwardena, Derek A O'Reilly
BACKGROUND: International guidelines for the management of acute pancreatitis state that antibiotics should only be used to treat infectious complications. Antibiotic prophylaxis is not recommended. The aim of this study was to analyse antibiotic use, and its appropriateness, from a national review of acute pancreatitis. METHODS: Data were collected from The National Confidential Enquiry into Patient Outcome and Death (NCEPOD) study into the management of acute pancreatitis...
May 24, 2018: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
John J Atherton, Andrew Sindone, Carmine G De Pasquale, Andrea Driscoll, Peter S MacDonald, Ingrid Hopper, Peter Kistler, Tom G Briffa, James Wong, Walter P Abhayaratna, Liza Thomas, Ralph Audehm, Phillip J Newton, Joan O'Loughlin, Cia Connell, Maree Branagan
Heart failure (HF) is a clinical syndrome that is secondary to an abnormality of cardiac structure or function. These clinical practice guidelines focus on the diagnosis and management of HF with recommendations that have been graded on the strength of evidence and the likely absolute benefit versus harm. Additional considerations are presented as practice points. Main recommendations: Blood pressure and lipid lowering decrease the risk of developing HF. Sodium-glucose cotransporter 2 inhibitors decrease the risk of HF hospitalisation in patients with type 2 diabetes and cardiovascular disease...
August 2, 2018: Medical Journal of Australia
Nicolas Postel-Vinay, Guillaume Bobrie, Sébastien Savard, Alexandre Persu, Laurence Amar, Michel Azizi, Gianfranco Parati
: Ambulatory blood pressure (BP) monitoring is encouraged by all international guidelines for the management of hypertension. Home BP monitoring is the preferred method of the patients. Automated BP devices with remote data transmission have been repeatedly shown to be useful in improving hypertension control in the frame of clinical trials on telemedicine. Recently, new technologies have created a new context. Despite the important number of smartphone apps devoted to BP developed these last 10 years, only two BP monitoring apps refer to the European Society of Hypertension (ESH) Guidelines and have been published in peer-reviewed journals: Hy-Result and ESH CARE...
July 30, 2018: Journal of Hypertension
Ignacio Martin-Loeches, Alejandro H Rodriguez, Antoni Torres
PURPOSE OF REVIEW: The International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia were published in 2017 whilst the American guidelines for Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia were launched in 2016 by the Infectious Diseases Society of America/ATS. Both guidelines made updated recommendations based on the most recent evidence sharing not only some parallelisms but also important conceptual differences...
July 30, 2018: Current Opinion in Critical Care
Fatoumata Matokoma Sidibe, Zakaria Traore, Aspasia Georgala, Rajae Kanab, Denis Larsimont, Ahmad Awada, Martine Piccart-Gebhart
Endometrial small cell carcinoma (ESCC) is an extremely rare and aggressive tumor with poor prognosis. It is characterized by early regional and systemic spread leading to rapid development of lymph nodes, pelvic and extrapelvic metastasis and compromising the outcome. In this paper, we reported three cases of ESCC confirmed by pathological and immunohistochemistry studies. In one case, ESCC was associated with endometrioid carcinoma and carcinosarcoma, while the other two cases were pure ESCC. Two cases were diagnosed at early stage IA of the International Federation of Gynecology and Obstetrics (FIGO) cancer staging system...
July 26, 2018: Bulletin du Cancer
Uri Donnett, Kristina Hubbard, Kimberly Woodruff, Andrea Varela-Stokes
Understanding diagnosis of heartworm disease in the context of animal shelters' needs and expectations is crucial for developing guidelines that specifically address the unique shelter population. Accurate and economical heartworm testing strategies are essential. However, current comprehensive guidelines for the management of heartworm disease in dogs are directed toward client-owned animals and do not address needs of animal shelters and other resource-scarce facilities. Additionally, testing recommendations do not take into account regional and local differences in heartworm prevalence across the United States that occur due to abiotic and biotic factors...
August 15, 2018: Veterinary Parasitology
Janick Selves, Benoit Terris, Dominique Cazals-Hatem, Jean-François Fléjou
The therapeutic management of malignant colorectal polyp with endoscopic resection is mainly based on specific histopathological criteria. The quality of these criteria is strongly linked to the management of the endoscopic specimen. The French Pathology Society drafted a standardized pathological report with guidelines for the macroscopic management of the endoscopic specimen and explanatory notes for each histopathological criteria. These guidelines are based on the TNM AJCC/UICC classification, 8th edition and the WHO 2010 classification of colorectal tumors, the recommendations of the French Society of Digestive Endoscopy, the synthesis of the literature and on international consensus for prognostic criteria...
July 26, 2018: Annales de Pathologie
David Cibula, Richard Pötter, François Planchamp, Elisabeth Avall-Lundqvist, Daniela Fischerova, Christine Haie-Meder, Christhardt Köhler, Fabio Landoni, Sigurd Lax, Jacob Christian Lindegaard, Umesh Mahantshetty, Patrice Mathevet, W Glenn McCluggage, Mary McCormack, Raj Naik, Remi Nout, Sandro Pignata, Jordi Ponce, Denis Querleu, Francesco Raspagliesi, Alexandros Rodolakis, Karl Tamussino, Pauline Wimberger, Maria Rosaria Raspollini
Regrettably, the author metadata used for the previous correction (doi: ) contained an error in the tagging of W. Glenn McCluggage's name; this has been corrected. No further adjustments have been made to the Correction, or the original Guideline paper (doi: ).
July 25, 2018: Virchows Archiv: An International Journal of Pathology
Pier Luigi Filosso, Francesco Guerrera, Nicola Rosario Falco, Pascal Thomas, Mariano Garcia Yuste, Gaetano Rocco, Stefan Welter, Paula Moreno Casado, Erino Angelo Rendina, Federico Venuta, Luca Ampollini, Mario Nosotti, Federico Raveglia, Ottavio Rena, Franco Stella, Valentina Larocca, Francesco Ardissone, Alessandro Brunelli, Stefano Margaritora, William D Travis, Dariusz Sagan, Inderpal Sarkaria, Andrea Evangelista
OBJECTIVES: Typical carcinoids (TCs) are rare, slow-growing neoplasms, usually characterized by satisfactory surgical outcomes. Due to the rarity of TCs, international guidelines for the management of particular clinical presentations currently do not exist. In particular, non-anatomical resections (wedges) are sometimes advocated for Stage 1 TCs because of their indolent behaviour. The aim of this paper was to evaluate the most effective type of surgery for Stage 1 TCs, using the European Society of Thoracic Surgeons retrospective database of the Neuroendocrine Tumors of the Lung Working Group...
July 18, 2018: European Journal of Cardio-thoracic Surgery
Naim Alkhouri, Fred Poordad, Eric Lawitz
Nonalcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of insulin resistance, which is the hallmark of type 2 diabetes (T2D). NAFLD is a known risk factor for developing T2D and has a very high prevalence in those with existing T2D. The diabetes spectrum includes several conditions from prediabetes to T2D to insulin-dependent diabetes leading to macrovascular and microvascular complications. Similarly, NAFLD has a histologic spectrum that ranges from the relatively benign nonalcoholic fatty liver to the aggressive form of nonalcoholic steatohepatitis with or without liver fibrosis to nonalcoholic steatohepatitis-cirrhosis leading to end-stage liver disease...
July 2018: Hepatology communications
A Ross Naylor
The European Society for Vascular Surgery (ESVS) has recently prepared updated guidelines for the management of patients with symptomatic and asymptomatic atherosclerotic carotid artery disease, with specific reference to the roles of best medical therapy, carotid endarterectomy (CEA) and carotid artery stenting (CAS). In symptomatic patients, there is a drive towards performing carotid interventions as soon as possible after onset of symptoms. This is because it is now recognised that the highest risk period for recurrent stroke is the first 7-14 days after onset of symptoms...
June 2018: Stroke and Vascular Neurology
Durga Prasanna Misra, Aman Sharma, Vikas Agarwal
The practice of rheumatology in a country like India presents its own unique challenges, including the need to manage patients in a cost-constrained setting, where the lack of uniform government funding for healthcare merits the need to optimize the use of cheaper medicines, as well as devise innovative strategies to minimize the use of costlier drugs such as biologic disease-modifying agents. Use of immunosuppressive agents is also associated with increased risks of infectious complications, such as the reactivation of tuberculosis...
July 19, 2018: Rheumatology International
Yi-Heng Li, Yu-Chen Wang, Yi-Chih Wang, Ju-Chi Liu, Cheng-Han Lee, Chun-Chi Chen, I-Chang Hsieh, Feng-You Kuo, Wei-Chun Huang, Shih-Hsien Sung, Chiung-Zuan Chiu, Jung-Cheng Hsu, Shu-Long Jen, Juey-Jen Hwang, Jiunn-Lee Lin
In Taiwan, the incidence of non-ST segment elevation acute coronary syndrome (NSTE-ACS) continues to increase in recent years. The purpose of this guideline is to help health care professionals in Taiwan to use adequate tests and treatments for management of NSTE-ACS. For rapid diagnosis, in addition to history and physical examination, 0/3 h rapid diagnosis protocol with high sensitivity cardiac troponin assay is recommended in this guideline. Dual antiplatelet and anticoagulation therapies are important parts in the initial treatment...
July 12, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
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