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https://www.readbyqxmd.com/read/30052610/individualized-treatment-for-infantile-hemangioma
#1
Meng-Nan Xu, Min Zhang, Yuan Xu, Min Wang, Si-Ming Yuan
Infantile hemangioma can grow dramatically or typically locate on the face, which may lead to functional impairment, cosmetically disfiguring and exhibiting complications such as ulceration, bleeding, or infection. Early intervention is necessary. In this study, the authors chose individual treatment for different patients. From January 2012 to December 2016, 185 patients with hemangioma were enrolled into this study. Lesion area ranged from 0.5 cm × 0.5 cm to 9 cm × 12 cm. The initial treatment age ranged from 1 to 7 months with an average age of 3...
July 26, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/30050362/protein-losing-enteropathy-and-joint-contractures-caused-by-a-novel-homozygous-antxr2-mutation
#2
Edith Schussler, Rita V Linkner, Jacob Levitt, Lakshmi Mehta, John A Martignetti, Kimihiko Oishi
Infantile systemic hyalinosis (ISH) is a rare autosomal recessive disorder and an allelic form of hyaline fibromatosis syndrome that is caused by mutations in the ANTRX2 gene encoding the transmembrane anthrax toxin receptor 2. Its main features include characteristic skin lesions, joint contractures, persistent diarrhea, and failure to thrive due to accumulation of hyaline material in multiple organs. The resulting severe malnutrition can cause death in early infancy. Because of its rarity and high fatality rate, timely diagnosis is difficult and ISH may be underdiagnosed...
2018: Advances in Genomics and Genetics
https://www.readbyqxmd.com/read/29804008/chronic-sequelae-and-severe-complications-of-norovirus-infection-a-systematic-review-of-literature
#3
REVIEW
Mariska Petrignani, Linda Verhoef, Miranda de Graaf, Jan Hendrik Richardus, Marion Koopmans
Norovirus causes an estimated 18% of all cases of acute gastroenteritis worldwide and is found to be associated with mortality. To create a first overview of severe complications and chronic sequelae of norovirus infections, a systematic review of literature was performed. Of 3928 individual hits, 176 publications remained for data extraction. Study periods varied between 1974 and 2017, though strongly skewed towards the last decade (n = 122, 70%). Countries of studies were worldwide, though Africa, and Carribean, Central and South America were underrepresented...
August 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29607365/frequency-distribution-of-porcine-rotavirus-a-and-capsid-protein-gene-based-sequence-and-phylogenetic-analysis-indicating-marked-heterogeneity-among-prevailing-strains-india
#4
Jobin Jose Kattoor, Sharad Saurabh, Shubhankar Sircar, Obli Rajendran Vinodhkumar, Ujjwal Kumar De, Kuldeep Dhama, Souvik Ghosh, Raj Kumar Singh, Yashpal Singh Malik
Rotavirus (RV), is an etiological agent of acute infantile diarrhea in both humans and animals including poultry. Among the eight accepted species/types of RVs, RV-A is genetically and antigenically the most diverse. RV-A associated enteritis is a major problem in the weaning and post-weaning piglets. Due to high genetic variability in the antigenic regions, RV-A is thought to have high interspecies jumping probability. In this study, comparatively a large sized sample (n = 757) was screened, where the samples were collected from diarrheic porcine population of north (Uttar Pradesh), North eastern (Assam, Nagaland, Meghalaya, Tripura, Manipur, Mizoram and Arunachal Pradesh) and Southern states of India (Kerala, Karnataka and Tamil Nadu)...
March 2018: Virusdisease
https://www.readbyqxmd.com/read/29560583/treatment-with-chenodeoxycholic-acid-in-cerebrotendinous-xanthomatosis-clinical-neurophysiological-and-quantitative-brain-structural-outcomes
#5
Maria Del Mar Amador, Marion Masingue, Rabab Debs, Foudil Lamari, Vincent Perlbarg, Emmanuel Roze, Bertrand Degos, Fanny Mochel
BACKGROUND: Cerebrotendinous xanthomatosis (CTX) is a rare neurodegenerative disease related to sterols metabolism. It affects both central and peripheral nervous systems but treatment with chenodeoxycholic acid (CDCA) has been reported to stabilize clinical scores and improve nerve conduction parameters. Few quantitative brain structural studies have been conducted to assess the effect of CDCA in CTX. METHODS AND RESULTS: We collected retrospectively clinical, neurophysiological, and quantitative brain structural data in a cohort of 14 patients with CTX treated by CDCA over a mean period of 5 years...
March 20, 2018: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/29483944/molecular-detection-of-human-enteric-viruses-circulating-among-children-with-acute-gastroenteritis-in-valencia-venezuela-before-rotavirus-vaccine-implementation
#6
Ana C Alcalá, Kriss Pérez, Ruth Blanco, Rosabel González, Juan E Ludert, Ferdinando Liprandi, Esmeralda Vizzi
Background: The role of rotavirus as main etiologic agent of diarrhea has been well documented worldwide, including in Venezuela. However, information about the prevalence of gastrointestinal viruses such as calicivirus, adenovirus and astrovirus is limited and the contribution of other agents as Aichi virus and klassevirus is largely unknown. To explore the etiological spectrum of diarrhea associated with agents other than rotaviruses, 227 stool samples from children under 5 years old with acute gastroenteritis, collected in Valencia (Venezuela) from 2001 to 2005, and previously tested as rotavirus-negative, were analyzed for caliciviruses, adenoviruses, astroviruses, Aichi viruses, klasseviruses, picobirnaviruses and enteroviruses by specific RT-PCRs...
2018: Gut Pathogens
https://www.readbyqxmd.com/read/29390480/nutritional-therapy-and-effect-assessment-of-infants-with-primary-intestinal-lymphangiectasia-case-reports
#7
Suyun Li, Xiaoqian Liu, Yuan He, Qianyu Li, Linlin Ji, Wenbin Shen, Guansheng Tong
RATIONALE: Intestinal lymphangiectasia (IL) is a rare enteropathy involving the expansion and rupture of intestinal lymphatic channels. Although several reports have studied cases of primary IL (PIL), this condition is very rare, and is even less commonly encountered in infants. This study aimed to investigate the nutritional therapy and effect assessment of chylous reflux disorder caused by PIL in infants. PATIENT CONCERNS: Infantile patients were enrolled in the Affiliated Beijing Shijitan Hospital of the Capital Medical University between January 2012 and March 2014...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29358865/fecal-microbiota-transplantation-induces-remission-of-infantile-allergic-colitis-through-gut-microbiota-re-establishment
#8
Sheng-Xuan Liu, Yin-Hu Li, Wen-Kui Dai, Xue-Song Li, Chuang-Zhao Qiu, Meng-Ling Ruan, Biao Zou, Chen Dong, Yan-Hong Liu, Jia-Yi He, Zhi-Hua Huang, Sai-Nan Shu
AIM: To investigate the impact of fecal microbiota transplantation (FMT) treatment on allergic colitis (AC) and gut microbiota (GM). METHODS: We selected a total of 19 AC infants, who suffered from severe diarrhea/hematochezia, did not relieve completely after routine therapy or cannot adhere to the therapy, and were free from organ congenital malformations and other contraindications for FMT. Qualified donor-derived stools were collected and injected to the AC infants via a rectal tube...
December 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29259371/probiotics-for-gastrointestinal-disorders-proposed-recommendations-for-children-of-the-asia-pacific-region
#9
REVIEW
Donald Cameron, Quak Seng Hock, Musal Kadim, Neelam Mohan, Eell Ryoo, Bhupinder Sandhu, Yuichiro Yamashiro, Chen Jie, Hans Hoekstra, Alfredo Guarino
Recommendations for probiotics are available in several regions. This paper proposes recommendations for probiotics in pediatric gastrointestinal diseases in the Asia-Pacific region. Epidemiology and clinical patterns of intestinal diseases in Asia-Pacific countries were discussed. Evidence-based recommendations and randomized controlled trials in the region were revised. Cultural aspects, health management issues and economic factors were also considered. Final recommendations were approved by applying the Likert scale and rated using the GRADE system...
December 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29246337/50-years-ago-in-the-journal-of-pediatrics-epidemiology-and-etiology-of-severe-infantile-diarrhea
#10
Dheeraj Shah
No abstract text is available yet for this article.
January 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29145277/tricho-hepato-enteric-syndrome-with-novel-skiv2l-gene-mutations-a-case-report
#11
Eitaro Hiejima, Takahiro Yasumi, Hiroshi Nakase, Minoru Matsuura, Yusuke Honzawa, Hirokazu Higuchi, Ikuo Okafuji, Tohru Yorifuji, Takayuki Tanaka, Kazushi Izawa, Tomoki Kawai, Ryuta Nishikomori, Toshio Heike
RATIONALE: Tricho-hepato-enteric syndrome (THES) is a rare disorder caused by mutations in the TTC37 or SKIV2L genes and characterized by chronic diarrhea, liver disease, hair abnormalities, and high mortality in early childhood due to severe infection or liver cirrhosis. PATIENT CONCERNS: The patient is the second child of three siblings born to non-consanguineous healthy Japanese parents. She had intrauterine growth retardation and was delivered at 33 weeks of gestation due to placental abruption...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29140941/phenotype-and-management-of-infantile-onset-inflammatory-bowel-disease-experience-from-a-tertiary-care-center-in-china
#12
Ziqing Ye, Ying Zhou, Ying Huang, Yuhuan Wang, Junping Lu, Zifei Tang, Shijian Miao, Kuiran Dong, Zhinong Jiang
BACKGROUND: Infantile-onset inflammatory bowel disease (IBD) comprises rare and clinically severe disorders. We examined the phenotypes and genetic causes of patients with infantile-onset IBD from a tertiary medical center. METHODS: We enrolled 38 patients with infantile-onset IBD and applied standardized treatment with medical, surgical, and supportive care. Targeted sequencing and whole-exome sequencing were performed. Clinical data were retrieved from medical records...
December 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29034106/epidemiology-and-antibiotic-resistance-phenotypes-of-diarrheagenic-escherichia-coli-responsible-for-infantile-gastroenteritis-in-ouagadougou-burkina-faso
#13
Ali Konaté, René Dembélé, Nathalie K Guessennd, Fernique Konan Kouadio, Innocent Kouamé Kouadio, Mohamed Baguy Ouattara, Wendpoulomdé A D Kaboré, Assèta Kagambèga, Haoua Cissé, Hadiza Bawa Ibrahim, Touwendsida Serge Bagré, Alfred S Traoré, Nicolas Barro
The emergence and persistence of multidrug-resistant (MDR) diarrheagenic Escherichia coli (DEC) causing acute diarrhea is a major public health challenge in developing countries. The aim of this study was to evaluate the resistance phenotypes of DEC isolated from stool samples collected from children less than 5 years of age with acute diarrhea living in Ouagadougou/Burkina Faso. From August 2013 to October 2015, this study was carried out on 31 DEC strains of our study conducted in "Centre Médical avec Antenne Chirurgicale (CMA)" Paul VI and CMA of Schiphra...
September 2017: European Journal of Microbiology & Immunology
https://www.readbyqxmd.com/read/29026779/oral-rehydration-solution-in-infantile-diarrhea-make-sure-it-is-given-properly
#14
Rohit Anand, Anirban Mandal, Amitabh Singh
No abstract text is available yet for this article.
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28894950/autism-spectrum-disorder-an-early-and-frequent-feature-in-cerebrotendinous-xanthomatosis
#15
Bianca M L Stelten, Olivier Bonnot, Hidde H Huidekoper, Francjan J van Spronsen, Peter M van Hasselt, Leo A J Kluijtmans, Ron A Wevers, Aad Verrips
BACKGROUND: Cerebrotendinous xanthomatosis (CTX) is an autosomal recessively inherited inborn error of metabolism (IEM) due to mutations in the CYP27A1 gene. The clinical picture ranges from being nearly asymptomatic in early childhood, up to severe disability at adult age. Infantile-onset diarrhea and juvenile-onset cataract are the earliest symptoms in childhood. In the current study, we evaluated the presence of autism spectrum disorder (ASD) in a large cohort of CTX patients. METHODS: We performed a retrospective patient file study in 77 genetically confirmed Dutch CTX patients to determine the frequency of ASD...
July 2018: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/28745994/case-23-2017-a-9-day-old-girl-with-vomiting-acidosis-and-azotemia
#16
Jason M Shapiro, Rene Balza, Navneet K Virk Hundal, Paul E Hesterberg, Lawrence R Zukerberg
Presentation of Case. Dr. Katherine L. Tuttle (Pediatrics): A 9-day-old girl was admitted to this hospital because of nonbilious vomiting, acidosis, and azotemia. The patient had been born at another hospital by induced vaginal delivery after 41 weeks 3 days of gestation. The pregnancy had been..
July 27, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28735819/meta-analysis-of-the-effects-of-bifidobacterium-preparations-for-the-prevention-and-treatment-of-pediatric-antibiotic-associated-diarrhea-in-china
#17
Hong-Bin Xu, Rui-Hua Jiang, Hong-Bin Sheng
Bifidobacterium preparations are increasingly used for pediatric antibiotic-associated diarrhea (AAD) in China. The aim of this study was to review existing evidence on the efficacy of Bifidobacterium preparations for the prevention and treatment of pediatric AAD in China. Searches were performed with Medline, Embase, Cochrane Central Register of Controlled Trials, CNKI, and CBM databases. Thirty trials met the inclusion criteria. Of the 30 trials, five Bifidobacterium preparations were included. The preparations were all Bifidobacterium based, in combined with Lactobacillus, Enterococcus, Bacillus, Streptococcus or Clostridium strains...
August 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28693504/prevalence-of-multi-drug-resistant-enteropathogenic-and-enteroinvasive-escherichia-coli-isolated-from-children-with-and-without-diarrhea-in-northeast-indian-population
#18
Karuppasamy Chellapandi, Tapan Kumar Dutta, Indu Sharma, Surajit De Mandal, Nachimuthu Senthil Kumar, Lalsanglura Ralte
BACKGROUND: Diarrheagenic Escherichia coli are associated with infantile diarrhea in the developing countries. The present study was conducted to determine the occurrence and antimicrobial resistance pattern of enteropathogenic and enteroinvasive E. coli associated with diarrhoea among the paediatric patients. METHODS: A total of 262 stool samples were collected from children with and without diarrhea from Mizoram, Northeast India. E. coli were isolated and subjected to multiplex PCR to detect virulent genes of EPEC (eaeA and bfpA) and EIEC (ial)...
July 11, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/28674052/characterization-of-a-large-antibiotic-resistance-plasmid-found-in-enteropathogenic-escherichia-coli-strain-b171-and-its-relatedness-to-plasmids-of-diverse-e-coli-and-shigella-strains
#19
Tracy H Hazen, Jane Michalski, Sushma Nagaraj, Iruka N Okeke, David A Rasko
Enteropathogenic Escherichia coli (EPEC) is a leading cause of severe infantile diarrhea in developing countries. Previous research has focused on the diversity of the EPEC virulence plasmid, whereas less is known regarding the genetic content and distribution of antibiotic resistance plasmids carried by EPEC. A previous study demonstrated that in addition to the virulence plasmid, reference EPEC strain B171 harbors a second, larger plasmid that confers antibiotic resistance. To further understand the genetic diversity and dissemination of antibiotic resistance plasmids among EPEC strains, we describe the complete sequence of an antibiotic resistance plasmid from EPEC strain B171...
September 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28441830/-a-case-of-tricho-hepato-enteric-syndrome
#20
J J Chen, L P Shi
No abstract text is available yet for this article.
April 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
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