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Tracheobronchitis

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https://www.readbyqxmd.com/read/30027437/necrotizing-tracheobronchitis-caused-by-influenza-and-staphylococcus-aureus-co-infection
#1
Saeko Takahashi, Morio Nakamura
No abstract text is available yet for this article.
July 19, 2018: Infection
https://www.readbyqxmd.com/read/30003304/assessing-predictive-accuracy-for-outcomes-of-ventilator-associated-events-in-an-international-cohort-the-euvae-study
#2
Sergio Ramírez-Estrada, Leonel Lagunes, Yolanda Peña-López, Amir Vahedian-Azimi, Saad Nseir, Kostoula Arvaniti, Aliye Bastug, Izarne Totorika, Nefise Oztoprak, Lilla Bouadma, Despoina Koulenti, Jordi Rello
PURPOSE: To analyze the impact on patient outcome of ventilator-associated events (VAEs) as defined by the Centers for Disease Control and Prevention (CDC) in 2008, 2013, and the correlation with ventilator-associated pneumonia (VAP) or tracheobronchitis (VAT). METHODS: This was a prospective, observational, multicenter, international study conducted at 13 intensive care units (ICUs); thirty consecutive adults mechanically ventilated for ≥ 48 h per site were eligible, with daily follow-up being recorded in a collaborative web database; VAEs were assessed using the 2013 CDC classification and its 2015 update...
July 12, 2018: Intensive Care Medicine
https://www.readbyqxmd.com/read/29987241/treatment-of-infections-due-to-aspergillus-terreus-species-complex
#3
REVIEW
Cornelia Lass-Flörl
The Aspergillus terreus species complex is found in a wide variety of habitats, and the spectrum of diseases caused covers allergic bronchopulmonary aspergillosis, Aspergillus bronchitis and/or tracheobronchitis, and invasive and disseminated aspergillosis. Invasive infections are a significant cause of morbidity and mortality mainly in patients with hematological malignancy. The section Terrei covers a total of 16 accepted species of which most are amphotericin B resistant. Triazoles are the preferred agents for treatment and prevention of invasive aspergillosis...
July 9, 2018: Journal of Fungi (Basel, Switzerland)
https://www.readbyqxmd.com/read/29922077/differential-characteristics-of-acinetobacter-baumannii-colonization-and-infection-risk-factors-clinical-picture-and-mortality
#4
Andrés Martín-Aspas, Francisca M Guerrero-Sánchez, Francisco García-Colchero, Sebastián Rodríguez-Roca, José-Antonio Girón-González
Objectives: The objectives of this study were to detect those characteristics that were specifically associated with infection or colonization by Acinetobacter baumannii , describe the clinical manifestations of those patients in whom the infection was detected in intensive care unit (ICU) or non-ICU wards, and analyze the prognosis-associated factors in patients from whom A. baumannii was isolated. Patients and methods: A sample of 122 patients from whom A. baumannii was recovered during an endemic period in a teaching hospital was included...
2018: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29800471/fatal-fulminant-herpetic-tracheobronchitis-following-cardiac-surgery
#5
Pradeep Vaideeswar, Supreet P Marathe
Nosocomial infection is a feared complication after any surgical procedure. Respiratory tract microbial colonization and development of ventilator-associated tracheobronchitis and/or pneumonia are unfortunate sequelae in mechanically ventilated patients, commonly caused by bacteria; viral etiology is seldom anticipated. We present a fatal case of fulminant herpetic tracheobronchitis in a 33-month-old patient following cardiac surgery. We intend to highlight the fact that herpetic viral etiology should be considered in post-operative respiratory infections...
May 25, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29742211/antibiotic-therapy-in-ventilator-associated-tracheobronchitis-a-literature-review
#6
Abel Eduardo Alves, José Manuel Pereira
The concept of ventilator-associated tracheobronchitis is controversial; its definition is not unanimously accepted and often overlaps with ventilator-associated pneumonia. Ventilator-associated tracheobronchitis has an incidence similar to that of ventilator-associated pneumonia, with a high prevalence of isolated multiresistant agents, resulting in an increase in the time of mechanical ventilation and hospitalization but without an impact on mortality. The performance of quantitative cultures may allow better diagnostic definition of tracheobronchitis associated with mechanical ventilation, possibly avoiding the overdiagnosis of this condition...
March 2018: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/29699468/lower-respiratory-tract-infection-and-short-term-outcome-in-patients-with-acute-respiratory-distress-syndrome
#7
Fernando G Zampieri, Pedro Póvoa, Jorge I Salluh, Alejandro Rodriguez, Sandrine Valade, José Andrade Gomes, Jean Reignier, Elena Molinos, Jordi Almirall, Nicolas Boussekey, Lorenzo Socias, Paula Ramirez, William N Viana, Anahita Rouzé, Saad Nseir, Ignacio Martin-Loeches
OBJECTIVE: To assess whether ventilator-associated lower respiratory tract infections (VA-LRTIs) are associated with mortality in critically ill patients with acute respiratory distress syndrome (ARDS). MATERIALS AND METHODS: Post hoc analysis of prospective cohort study including mechanically ventilated patients from a multicenter prospective observational study (TAVeM study); VA-LRTI was defined as either ventilator-associated tracheobronchitis (VAT) or ventilator-associated pneumonia (VAP) based on clinical criteria and microbiological confirmation...
January 1, 2018: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29616405/ventilator-associated-pneumonia-in-pediatric-intensive-care-unit-incidence-risk-factors-and-etiological-agents
#8
Gnanaguru Vijay, Anirban Mandal, Jhuma Sankar, Arti Kapil, Rakesh Lodha, S K Kabra
OBJECTIVES: To study the incidence, etiology and risk factors associated with ventilator associated pneumonia (VAP) in children. METHODS: This prospective cohort study was conducted on patients admitted to the Pediatric Intensive Care Unit (PICU) of a tertiary care institute of North India, from June 2012 through March 2014, who received mechanical ventilation for more than 24 h. All enrolled children were assessed daily for development of ventilator associated pneumonia (VAP) using the case definition given by Centers for Disease Control and Prevention (CDC)...
April 4, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29615093/continuous-versus-intermittent-endotracheal-cuff-pressure-control-for-the-prevention-of-ventilator-associated-respiratory-infections-in-vietnam-study-protocol-for-a-randomised-controlled-trial
#9
Vu Quoc Dat, Ronald B Geskus, Marcel Wolbers, Huynh Thi Loan, Lam Minh Yen, Nguyen Thien Binh, Le Thanh Chien, Nguyen Thi Hoang Mai, Nguyen Hoan Phu, Nguyen Phu Huong Lan, Nguyen Van Hao, Hoang Bao Long, Tran Phuong Thuy, Nguyen Van Kinh, Nguyen Vu Trung, Vu Dinh Phu, Nguyen Trung Cap, Dao Tuyet Trinh, James Campbell, Evelyne Kestelyn, Heiman F L Wertheim, Duncan Wyncoll, Guy Edward Thwaites, H Rogier van Doorn, C Louise Thwaites, Behzad Nadjm
BACKGROUND: Ventilator-associated respiratory infection (VARI) comprises ventilator-associated pneumonia (VAP) and ventilator-associated tracheobronchitis (VAT). Although their diagnostic criteria vary, together these are the most common hospital-acquired infections in intensive care units (ICUs) worldwide, responsible for a large proportion of antibiotic use within ICUs. Evidence-based strategies for the prevention of VARI in resource-limited settings are lacking. Preventing the leakage of oropharyngeal secretions into the lung using continuous endotracheal cuff pressure control is a promising strategy...
April 4, 2018: Trials
https://www.readbyqxmd.com/read/29583108/bronchoscopic-improvement-of-tracheobronchitis-due-to-methicillin-resistant-staphylococcus-aureus-after-aerosolized-vancomycin-a-case-series
#10
Jun Yeun Cho, Youlim Kim, Sang Hoon Lee, Yeon Joo Lee, Jong Sun Park, Ho Il Yoon, Jae-Joon Yim, Jae Ho Lee, Choon-Taek Lee, Young-Jae Cho
BACKGROUND: Ventilator-associated tracheobronchitis (VAT) is an important risk factor for ventilator-associated pneumonia (VAP). The efficacy of aerosolized vancomycin (AV) in treating VAT has not been clearly demonstrated. METHODS: Four mechanically ventilated patients with methicillin-resistant Staphylococcus aureus (MRSA) pneumonia were treated with an additional AV. AV (250 mg twice per day) was administered through a vibrating mesh device for 5 days. All patients were receiving intravenous vancomycin and had severe tracheobronchitis, based on bronchoscopic findings before or soon after additional AV treatment...
March 27, 2018: Journal of Aerosol Medicine and Pulmonary Drug Delivery
https://www.readbyqxmd.com/read/29506501/morbidity-and-mortality-related-to-pneumonia-and-tracheobronchitis-in-icu-after-lung-transplantation
#11
Sebastien Tanaka, Claire Geneve, Gianpiero Tebano, Nathalie Grall, Pascal Piednoir, Régis Bronchard, Mathieu Godement, Enora Atchade, Pascal Augustin, Herve Mal, Yves Castier, Philippe Montravers, Mathieu Desmard
BACKGROUND: Bacterial respiratory infections (BRI) are major complications contributing to increased morbidity and mortality after lung transplantation (LT). This study analyzed epidemiology and outcome of 175 consecutive patients developing BRI in ICU after LT between 2006 and 2012. METHODS: Three situations were described: colonization determined in donors and recipients, pneumonia and tracheobronchitis during the first 28 postoperative days. Severity score, demographic, bacteriologic and outcome data were collected...
March 5, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29484049/delayed-recurrence-of-ulcerative-colitis-manifested-by-tracheobronchitis-bronchiolitis-and-bronchiolectasis
#12
Iclal Ocak, Gideon Bollino, Carl Fuhrman
Ulcerative colitis can cause inflammation of small and large airways, characterized by mucosal inflammation, tracheobronchial stenosis, bronchiestasis, and bronchiolitis. We present a case of tracheobronchitis and bronchiolitis associated with ulcerative colitis in a 58-year-old nonsmoking man, 17 years after the total colectomy and complete resolution of intestinal findings. Computed tomography demonstrated wall thickening of trachea and left main stem bronchus, and multiple bronchi around the both hilum with mild to moderate stenosis...
December 2017: Radiology Case Reports
https://www.readbyqxmd.com/read/29422291/a-case-control-study-on-the-clinical-impact-of-ventilator-associated-tracheobronchitis-in-adult-patients-who-did-not-develop-ventilator-associated-pneumonia
#13
María Luisa Cantón-Bulnes, María Ascensión González-García, Manuela García-Sánchez, Ángel Arenzana-Seisdedos, José Garnacho-Montero
OBJECTIVES: The main objective was to determine whether ventilator-associated tracheobronchitis (VAT) is related to increased length of ICU stay. Secondary endpoints included prolongation of hospital stay, as well as, ICU and hospital mortality. DESIGN: A retrospective matched case-control study. Each case was matched with a control for duration of ventilation (± 2 days until development of ventilator-associated tracheobronchitis), disease severity (Acute Physiology and Chronic Health Evaluation II) at admission ± 3, diagnostic category and age ±10 years...
February 5, 2018: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29384483/occlusive-mycotic-tracheobronchitis-and-systemic-alphaherpesvirus-coinfection-in-a-free-living-striped-dolphin-stenella-coeruleoalba-in-italy
#14
Carla Grattarola, Federica Giorda, Barbara Iulini, Alessandra Pautasso, Marco Ballardini, Simona Zoppi, Letizia Marsili, Simone Peletto, Loretta Masoero, Katia Varello, Fulvio Garibaldi, Frine E Scaglione, Giovanni Di Guardo, Alessandro Dondo, Maria Goria, Laura Serracca, Walter Mignone, Cristina Casalone
A juvenile female striped dolphin Stenella coeruleoalba live stranded on 4 March 2016 at Alassio, western Ligurian Sea coast, Italy. The dolphin died shortly after stranding, and a complete postmortem examination was performed. Necropsy revealed severe tracheal occlusion and unilateral bronchial stenosis with luminal accumulation of abundant green-yellow mucous-gelatinous material. Histological features suggestive of tracheobronchial aspergillosis were observed. Cultures of lung tissue and tracheo-bronchial exudate isolated Aspergillus fumigatus, identified by a Microseq D2 LSUrDNA fungal sequencing kit...
January 31, 2018: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/29362229/-mycoplasma-pneumoniae-community-acquired-respiratory-distress-syndrome-toxin-uses-a-novel-keled-sequence-for-retrograde-transport-and-subsequent-cytotoxicity
#15
Kumaraguruparan Ramasamy, Sowmya Balasubramanian, Krishnan Manickam, Lavanya Pandranki, Alexander B Taylor, P John Hart, Joel B Baseman, T R Kannan
Mycoplasma pneumoniae is an atypical bacterium that causes respiratory illnesses in humans, including pharyngitis, tracheobronchitis, and community-acquired pneumonia (CAP). It has also been directly linked to reactive airway disease, asthma, and extrapulmonary pathologies. During its colonization, M. pneumoniae expresses a unique ADP-ribosylating and vacuolating cytotoxin designated <u>c</u>ommunity-<u>a</u>cquired <u>r</u>espiratory <u>d</u>istress <u>s</u>yndrome (CARDS) toxin...
January 23, 2018: MBio
https://www.readbyqxmd.com/read/29318460/nebulization-of-antimicrobial-agents-in-mechanically-ventilated-adults-in-2017-an-international-cross-sectional-survey
#16
Joana Alves, Emine Alp, Despoina Koulenti, Zhongheng Zhang, Stephan Ehrmann, Stijn Blot, Matteo Bassetti, Andrew Conway-Morris, Rosa Reina, Enrique Teran, Candela Sole-Lleonart, Maria Ruiz-Rodríguez, Jordi Rello
2017 ESCMID practice guidelines reported safety concerns and weak evidence of benefit supporting use of aerosolized antibiotics in mechanically ventilated patients. Our primary goal was to assess current patterns of aerosolized antibiotic prescription in mechanically ventilated patients. A sequential global survey was performed prior to the release of the ESCMID guidelines, from the 1st of February to the 30th of April 2017, using an electronic platform. Responses were analyzed comparing geographical regions...
April 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29213023/-tracheobronchitis-as-an-extraintestinal-manifestation-of-crohn-s-disease
#17
REVIEW
Ryosuke Sakemi, Suketo So, Yosuke Morimitsu, Tetsuhiro Noda, Kensei Ohtsu, Yoshihiko Karashima, Kentaro Imamura, Hiroya Terabe, Yasuo Chojin, Tatsuji Kato
A 27-year-old woman with Crohn's disease, who had sustained clinical remission for two years following treatment with mesalazine and nutrition therapy, was admitted to our hospital complaining of dry cough, mild dysphagia, and slight fever. A computed tomography of the chest demonstrated an increase in the thickness of the tracheal wall. Bronchoscopy showed a diffusely erythematous and edematous mucosa with whitish granular lesions in the trachea and main carina. Bronchial biopsy specimens showed epithelioid cell granuloma...
2017: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/29164144/intensive-care-unit-patients-with-lower-respiratory-tract-nosocomial-infections-the-enirris-project
#18
Gennaro De Pascale, Otavio T Ranzani, Saad Nseir, Jean Chastre, Tobias Welte, Massimo Antonelli, Paolo Navalesi, Eugenio Garofalo, Andrea Bruni, Luis Miguel Coelho, Szymon Skoczynski, Federico Longhini, Fabio Silvio Taccone, David Grimaldi, Helmut J F Salzer, Christoph Lange, Filipe Froes, Antoni Artigas, Emili Díaz, Jordi Vallés, Alejandro Rodríguez, Mauro Panigada, Vittoria Comellini, Luca Fasano, Paolo M Soave, Giorgia Spinazzola, Charles-Edouard Luyt, Francisco Alvarez-Lerma, Judith Marin, Joan Ramon Masclans, Davide Chiumello, Angelo Pezzi, Marcus Schultz, Hafiz Mohamed, Menno Van Der Eerden, Roger A S Hoek, D A M P J Gommers, Marta Di Pasquale, Rok Civljak, Marko Kutleša, Matteo Bassetti, George Dimopoulos, Stefano Nava, Fernando Rios, Fernando G Zampieri, Pedro Povoa, Lieuwe D Bos, Stefano Aliberti, Antoni Torres, Ignacio Martín-Loeches
The clinical course of intensive care unit (ICU) patients may be complicated by a large spectrum of lower respiratory tract infections (LRTI), defined by specific epidemiological, clinical and microbiological aspects. A European network for ICU-related respiratory infections (ENIRRIs), supported by the European Respiratory Society, has been recently established, with the aim at studying all respiratory tract infective episodes except community-acquired ones. A multicentre, observational study is in progress, enrolling more than 1000 patients fulfilling the clinical, biochemical and radiological findings consistent with a LRTI...
October 2017: ERJ Open Research
https://www.readbyqxmd.com/read/29116676/salvage-therapy-with-topical-posaconazole-in-lung-transplant-recipients-with-invasive-scedosporium-infection
#19
Amparo Solé, Ana A García-Robles, Carlos Jordá, Enrique Cases Viedma, Nuria Mancheño, José Luis Poveda-Andrés, Juan Pablo Reig Mezquida, Javier Pemán
Scedosporium is an important pathogen in cystic fibrosis (CF) and post-transplantation, but it rarely causes invasive infection. Treatment remains challenging, particularly due to the inherent resistance to multiple antifungal agents. We present 3 complicated invasive tracheobronchial and lung Scedosporium apiospermum infections following lung transplantation. In 2 of 3 cases, the infection was clinically and radiologically cured with frequent cleansing bronchoscopies, combining triazole with terbinafine therapy and nebulized posaconazole...
February 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29031787/assessing-prediction-accuracy-for-outcomes-of-ventilator-associated-events-and-infections-in-critically-ill-children-a-prospective-cohort-study
#20
Y Peña-López, M Pujol, M Campins, L Lagunes, J Balcells, J Rello
OBJECTIVES: To assess the prediction accuracy of the 2008 US Centers for Disease Control and Prevention (CDC) definitions for ventilator-associated pneumonia (VAP)/ventilator-associated tracheobronchitis (VAT), 2013 CDC definitions for ventilator-associated events (VAE) and a new VAE algorithm in the paediatric (Ped) population, the Ped-VAE. METHODS: We performed a prospective 13-month cohort study at a multidisciplinary paediatric intensive care unit (PICU). Primary endpoints were duration of ventilation episode, PICU or hospitalization length of stay from episode and episode mortality...
July 2018: Clinical Microbiology and Infection
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