Madina R Zhalbinova, Saule E Rakhimova, Ulan A Kozhamkulov, Gulbanu A Akilzhanova, Assel A Chinybayeva, Kenes R Akilzhanov, Nurlan K Shaimardanov, Anargul G Kuanysheva, Joseph H Lee, Ulykbek Y Kairov, Makhabbat S Bekbossynova, Ainur R Akilzhanova
Left ventricular assist device (LVAD) implantation is one of the mechanical circulatory support (MCS) treatments for advanced heart failure (HF) patients. MCS has emerged as a lifesaving therapy that improves patients' quality of life. However, MCS remains limited by a paradoxical coagulopathy accompanied by thrombosis and bleeding. The mechanisms of MCS thrombosis are increasingly being defined, but MCS-related bleeding, which is related to shear-mediated alteration of platelet function, remains poorly understood...
November 22, 2023: Journal of Clinical Medicine