keyword
https://read.qxmd.com/read/38333403/polypharmacy-in-atrial-fibrillation-a-prospective-analysis-of-mortality-and-ischemic-stroke-using-the-clinical-practice-research-datalink
#21
JOURNAL ARTICLE
Natasha Slater, Simon White, Martin Frisher
BACKGROUND: Observational studies of polypharmacy and the risk of death or stroke in individuals with atrial fibrillation (AF) have produced inconsistent findings. By using propensity score matching (PSM) and Cox regression, this study aimed to determine whether polypharmacy (five to nine medicines) in the 3 months following AF diagnosis, is associated with an increased risk of death or ischemic stroke, compared to non-polypharmacy (one to four medicines). METHODS: A prospective cohort study using data from the Clinical Practice Research Datalink (2006-2019)...
February 2024: Journal of Arrhythmia
https://read.qxmd.com/read/38333397/the-efficiency-and-safety-of-multidetector-computed-tomography-guided-transseptal-puncture-during-atrial-fibrillation-catheter-ablation
#22
JOURNAL ARTICLE
Yi Lu, Zhen Yuan, Chunhui Liu, Shenghui Ma, Li Shu, Zhejun Cai
BACKGROUND: Transseptal puncture (TSP) is a crucial technique for catheter ablation of atrial fibrillation (AF). Although intracardiac echo (ICE) facilitates a safe and accurate TSP, it is not widely used in developing countries because of the expense. This study evaluated the efficiency and safety of a novel cardiac multidetector computed tomography (MDCT)-guided TSP during AF catheter ablation. METHODS: The study consisted of two cohorts. In the index cohort, TSP procedure was performed under the guidance of ICE, and we recorded the angulation of right anterior oblique of X-ray projection...
February 2024: Journal of Arrhythmia
https://read.qxmd.com/read/38324858/differences-between-two-distinct-hypertrophic-cardiac-conditions-fabry-disease-versus-hypertrophic-cardiomyopathy
#23
JOURNAL ARTICLE
Onur Akhan, Mehmet Kış, Tuncay Güzel, Mehdi Zoghi
BACKGROUND: Hypertrophic cardiomyopathy (HCM) and Fabry disease (FD) are genetically inherited diseases with left ventricular hypertrophy (LVH) phenotype characteristics that cause adverse cardiac outcomes. OBJECTIVES: To investigate the demographic, clinical, biochemical, electrocardiographic (ECG), and echocardiographic (ECHO) differences between HCM and FD. METHODS: 60 HCM and 40 FD patients were analyzed retrospectively as a subanalysis of the 'LVH-TR study' after excluding patients with atrial fibrillation, pace rhythm, bundle branch blocks, and second and third-degree atrioventricular (AV) blocks...
January 2024: Arquivos Brasileiros de Cardiologia
https://read.qxmd.com/read/38321906/a-simple-score-for-predicting-paroxysmal-atrial-fibrillation-in-patients-with-embolic-stroke-of-undetermined-source-in-a-tunisian-cohort-study
#24
JOURNAL ARTICLE
Sana Ben Amor, Assil Achour, Aymen Elhraiech, Emna Jarrar, Hela Ghali, Ons Ben Ameur, Neserine Amara, Anis Hassine, Houyem Saied, Eleys Neffati, Didier Smadja
BACKGROUND: The annualized recurrent stroke rate in patients with Embolic Stroke of Undetermined Source (ESUS) under antiplatelet therapy is around 4.5%. Only a fraction of these patients will develop atrial fibrillation (FA), to which a stroke can be attributed retrospectively. The challenge is to identify patients at risk of occult AF during follow-up. OBJECTIVE: This work aims to determine clinical factors and electrocardiographic and ultrasound parameters that can predict occult AF in patients with ESUS and build a simple predictive score applicable worldwide...
February 6, 2024: Current Neurovascular Research
https://read.qxmd.com/read/38308162/endovascular-thrombectomy-for-dawn-and-defuse-3-ineligible-acute-ischemic-stroke-patients-a-systematic-review-and-meta-analysis
#25
REVIEW
Samah Morsi, Sherief Ghozy, Mohamed Elfil, Hatem Tolba, Alejandro Rabenstein, Ramanathan Kadirvel, David F Kallmes
BACKGROUND: Endovascular therapy (EVT) has been proven beneficial for treating acute ischemic strokes (AIS) with large vessel occlusion (LVO). Recent trials of DAWN and DEFUSE-3 have extended the treatment window to 6-24 h, sparking investigations into EVT outcomes for patients not eligible for DAWN/DEFUSE-3 criteria. PURPOSE: To assess the outcomes of endovascular therapy (EVT) for late-window anterior circulation large vessel occlusion (LVO) in acute ischemic stroke patients, comparing DAWN/DEFUSE-3 eligible (DD) and ineligible (NDND) groups...
February 3, 2024: Journal of Neurology
https://read.qxmd.com/read/38293361/global-burden-of-atrial-fibrillation-flutter-trends-from-1990-to-2019-and-projections-until-2044
#26
JOURNAL ARTICLE
Qunchao Ma, Jinyun Zhu, Pingping Zheng, Jiaru Zhang, Xiangyang Xia, Yun Zhao, Qingqiang Cheng, Ning Zhang
AIMS: Atrial fibrillation/atrial flutter (AF/AFL) is a critical public health issue worldwide, and its epidemiological patterns have changed over the decades. This work aimed to assess the global trends of AF/AFL and attributable risks from 1990 to 2019. METHODS AND RESULTS: The present study utilized data from the Global Burden of Disease Study 2019 to examine the temporal trends, attributable risks, and projections of AF/AFL. The estimated annual percentage change (EAPC) and age-standardized rate (ASR) were employed for this purpose...
January 30, 2024: Heliyon
https://read.qxmd.com/read/38291296/pulsed-field-versus-cryoballoon-ablation-for-atrial-fibrillation-a%C3%A2-real-world-observational-study-on-procedural-outcomes-and-efficacy
#27
JOURNAL ARTICLE
Mileen R D van de Kar, Stacey R Slingerland, Gijs J van Steenbergen, Tim Brouwer, Daniela N Schulz, Dennis van Veghel, Lukas Dekker
INTRODUCTION: Atrial fibrillation often necessitates catheter ablation when antiarrhythmic drug therapy fails. Single-shot technologies using thermal energy, such as cryoballoon ablation, are commonly used, but pulsed field ablation (PFA), an innovative non-thermal ablation technique, is a potential alternative. This retrospective observational study aimed to compare the safety and efficacy of cryoballoon ablation and PFA in patients undergoing their first pulmonary vein isolation (PVI) procedure for atrial fibrillation treatment...
January 30, 2024: Netherlands Heart Journal
https://read.qxmd.com/read/38287499/modified-application-of-same-tt2r2-scoring-system-in-asian-patients-with-atrial-fibrillation-for-the-selection-of-oral-anticoagulants
#28
JOURNAL ARTICLE
Seong Won Jeon, Nuri Lee, Ki Hong Lee, Minjeong Ha, Changhyun Kim, Yoo Ri Kim, Nam Sik Yoon, Hyung Wook Park
BACKGROUND/AIMS: The SAMe-TT2R2 score is used for assessing anticoagulation control (AC) quality with warfarin. However, it is hard to apply SAMe-TT2R2 score in Asian patients with atrial fibrillation (AF), because it has not been proven in those populations. This study aimed to validate the SAMe-TT2R2 score in Asian patients with AF and suggest a modified SAMe- TT2R2 score for this population. METHODS: We analyzed 710 Korean patients with AF who were using warfarin...
January 30, 2024: Korean Journal of Internal Medicine
https://read.qxmd.com/read/38269618/biometric-contrastive-learning-for-data-efficient-deep-learning-from-electrocardiographic-images
#29
JOURNAL ARTICLE
Veer Sangha, Akshay Khunte, Gregory Holste, Bobak J Mortazavi, Zhangyang Wang, Evangelos K Oikonomou, Rohan Khera
OBJECTIVE: Artificial intelligence (AI) detects heart disease from images of electrocardiograms (ECGs). However, traditional supervised learning is limited by the need for large amounts of labeled data. We report the development of Biometric Contrastive Learning (BCL), a self-supervised pretraining approach for label-efficient deep learning on ECG images. MATERIALS AND METHODS: Using pairs of ECGs from 78 288 individuals from Yale (2000-2015), we trained a convolutional neural network to identify temporally separated ECG pairs that varied in layouts from the same patient...
January 24, 2024: Journal of the American Medical Informatics Association: JAMIA
https://read.qxmd.com/read/38256299/prevalence-of-cardiovascular-comorbidities-in-patients-with-rheumatoid-arthritis
#30
JOURNAL ARTICLE
Marius Rus, Adriana Ioana Ardelean, Claudia Judea Pusta, Simina Crisan, Paula Marian, Liliana Oana Pobirci, Veronica Huplea, Alina Stanca Osiceanu, Gheorghe Adrian Osiceanu, Felicia Liana Andronie-Cioara, Madalina Ioana Guler
Background and Objectives : The risk of developing cardiovascular diseases (CVD) in patients suffering from rheumatoid arthritis (RA) is two times higher compared to the general population. The objective of this retrospective study was to determine which cardiovascular complications can appear in men vs. women with rheumatoid arthritis. Early diagnosis and initiation of therapeutic measures to reduce the progression rate of rheumatoid arthritis, while also maintaining an active lifestyle, are the most important problems in young patients...
December 25, 2023: Medicina
https://read.qxmd.com/read/38244982/validation-of-china-health-related-outcomes-measures-cardiovascular-disease
#31
JOURNAL ARTICLE
Xue Li, Rui Li, Feiyi Xiao, Kun Zhao, Xiaolu Zhang, Xinyi Wang, Meichen Li, Ke Guo, Li Wang, Yanan Wu, Harriette Van Spall, Tiantian Gao, Qiang Fu, Feng Xie
OBJECTIVES: China Health-Related Outcomes Measures (CHROME) was an initiative aimed at developing a system of preference-based health-related quality of life instruments for China. CHROME-cardiovascular disease (CVD) is a CVD-specific instrument with 14 items developed under this initiative. This study aimed to test the psychometric properties of CHROME-CVD. METHODS: This validation study was conducted using cross-sectional questionnaire survey in China. Eligible patients with CVD were recruited and asked to complete the CHROME-CVD, the EQ-5D-5L, and a CVD-specific nonpreference-based health-related quality of life instrument selected according to the confirmed diagnosis of the patients...
January 18, 2024: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://read.qxmd.com/read/38241091/retinal-vascular-dynamics-a-window-for-observing-an-irregular-heartbeat-a-case-report
#32
JOURNAL ARTICLE
Rebekka Heitmar, Paulus Kirchhoff, Andrew Blann, Konstantin Kotliar
OBJECTIVE: We aimed to characterize several aspects of retinal vascular dynamics in a patient with arrythmia in order to elicit additional diagnostic information on microvascular dysfunction. METHODS: A 68-year-old male patient with arrythmia and an age- and gender-matched control subject underwent ocular examination including dynamic retinal vessel assessment with flicker light provocation. Retinal vessel diameters were measured continuously following a standard protocol (IMEDOS Systems, Jena, Germany)...
January 19, 2024: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://read.qxmd.com/read/38236097/implication-of-threat-factors-and-preexisting-disorders-in-different-ischemic-stroke-subgroups-in-elderly-people-a-systematic-study
#33
JOURNAL ARTICLE
B Singh, S Mishra, R Kumar, D Patel J, H Malathi, B Kumar
Ischemic stroke is a major health issue, especially for the older population and it may have severe effects. Stroke diagnosis and treatment have advanced over the last 20 years, which has resulted in considerable reductions in death, long-term impairment, and the need for institutional care. Younger age groups have seen the majority of trials for acute, interventional, and preventive therapy. The purpose of this research was to identify distinct subgroups of older people who had suffered an ischemic stroke and examine the role that risk factors and previous illnesses played in their development...
November 2023: Georgian Medical News
https://read.qxmd.com/read/38218895/the-relationship-of-atrial-fibrillation-with-left-atrial-size-in-patients-with-essential-hypertension
#34
JOURNAL ARTICLE
Rami Saadeh, Bara Abu Jaber, Taqwa Alzuqaili, Sara Ghura, Taiba Al-Ajlouny, Abdallah M Saadeh
Atrial fibrillation (AF) is the most common sustained arrhythmia and it is a major public health problem worldwide. Hypertension is one of the major risk factors for the development of AF. This study is carried out to determine the prevalence and independent risk factors for atrial fibrillation (AF) in hypertensive patients and to evaluate the relationship of AF with left atrial size. This is a retrospective observational cross - sectional study that used a retrospective electronic chart review of all admitted patients to cardiology department at King Abdullah university hospital (KAUH) in Irbid, Jordan, with a diagnosis of hypertension along with various acute cardiac admissions, including AF during 1-year period (January 1st to December 31 of 2021)...
January 13, 2024: Scientific Reports
https://read.qxmd.com/read/38206802/long-term-outcomes-in-very-young-patients-with-myocardial-infarction-with-non-obstructive-coronary-arteries
#35
JOURNAL ARTICLE
Gokturk Ipek, Ali Nural, Ahmet Ceyhun Cebeci, Furkan Fatih Yucedag, Osman Bolca
Myocardial infarction (MI) with non-obstructive coronary arteries (MINOCA) covers an expanding group of patients over recent years. Previous studies showed considerable risks of outcomes in this group. However, there is a lack of evidence in young patients with MINOCA. In this study, we aimed to investigate the long-term outcomes in very young patients with MINOCA. We retrospectively compared the features and predictors of 183 very young (≤40-year-old) patients to >40-year-old patients with MINOCA...
January 12, 2024: Coronary Artery Disease
https://read.qxmd.com/read/38202244/concomitant-valve-replacement-and-coronary-artery-bypass-grafting-surgery-lessons-from-the-past-guidance-for-the-future-a-mortality-analysis-in-294-patients
#36
JOURNAL ARTICLE
Kyriakos Spiliopoulos, Dimitrios Magouliotis, Ilias Angelis, John Skoularigis, Bernhard M Kemkes, Nikolaos S Salemis, Thanos Athanasiou, Brigitte Gansera, Andrew V Xanthopoulos
OBJECTIVE: The aims of this study were to analyze parameters influencing early and late mortality after concomitant valve replacement and coronary artery bypass grafting surgery, using early and long-term information from an institutionally available data registry, and to discuss the results in relation to the current treatment strategies and perspectives. METHODS: The study population consisted of 294 patients after combined valve replacement with mechanical prosthesis and CABG surgery...
December 30, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/38193023/thyroid-dysfunction-and-mortality-in-cardiovascular-hospitalized-patients
#37
JOURNAL ARTICLE
Meir Frankel, Feras Bayya, Gabriel Munter, Arik Wolak, Lior Tolkin, Orit Barenhoz-Goultschin, Elad Asher, Michael Glikson
BACKGROUND: Thyroid dysfunction (TD) is associated with increased cardiovascular morbidity and mortality. Early detection may influence the clinical management. OBJECTIVE: To determine the prevalence, predictors, and prognostic value of TD among hospitalized cardiac patients. METHODS: A retrospective analysis of a 12-year database consisting of nonselectively adult patients admitted to a Cardiology Department and who were all screened for serum thyroid-stimulation-hormone (TSH) levels ...
March 2024: Cardiovascular endocrinology & metabolism
https://read.qxmd.com/read/38181644/gender-differences-with-ibutilide-effectiveness-and-safety-in-cardioversion-of-atrial-fibrillation
#38
JOURNAL ARTICLE
Aldin Malkoc, Alexander Phan, Payam Falatoonzadeh, Olivia Mac, William Sherman, David T Wong
INTRODUCTION: Few studies have examined the use of ibutilide in noncardiac surgical populations. Our study considered the effectiveness and safety of ibutilide in cardioversion of atrial fibrillation (AF) in medical and surgical intensive care patients. METHODS: A retrospective chart review was performed for patients with a confirmed diagnosis of AF who were hemodynamically stable and received ibutilide after the initial diagnosis. Patients were administered 1 mg of ibutilide fumarate intravenous for 10 min with a second dose administered if AF persisted after 30 min...
January 4, 2024: Journal of Surgical Research
https://read.qxmd.com/read/38169615/sex-differences-in-infective-endocarditis-a-systematic-review
#39
REVIEW
Ethan Slouha, Hanin Al-Geizi, Brandon R Albalat, Venkata Sathya Burle, Lucy A Clunes, Theofanis F Kollias
Despite the advancement in medicine, there is still a lack of understanding of the sex disparities in disease onset, progression, treatment, and outcome. In some life-threatening acute conditions, despite most patients with these illnesses being males, females have a significantly higher chance of mortality. This can be due to the differences in disease progression or healthcare disparities in managing the illness between the sexes. Treatment of illnesses tends to be more conservative for women without an explanation, but this disparity is due to the healthcare provider...
December 2023: Curēus
https://read.qxmd.com/read/38156488/predictors-of-reduced-left-ventricle-global-longitudinal-strain-one-year-after-covid-19-pneumonia
#40
JOURNAL ARTICLE
E I Yaroslavskaya, E A Gorbatenko, D V Krinochkin, N E Shirokov, N A Osokina, A V Migacheva, T I Petelina
Aim      To identify predictors of decreased left ventricular global longitudinal strain (LV GLS) using the method of speckle-tracking in gray scale one year after COVID-19-associated pneumonia in patients without ischemic heart disease (IHD), previous pulmonary embolism (PE), peripheral thrombosis, and atrial fibrillation (AF).Material and methods  The study included 156 patients from the Prospective Registry of People After COVID-19-Associated Pneumonia, with optimal visualization quality according to echocardiography (EchoCG), without IHD, AF, history of pulmonary embolism (PE), and peripheral thrombosis...
December 26, 2023: Kardiologiia
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