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Atrial Fibrillation And Gender

Gregory Y H Lip
AIM: Four non-vitamin K oral anticoagulants (NOACs) have been evaluated in clinical trials for the prevention of stroke in patients with atrial fibrillation (AF). Although each of the NOACs have been shown to be at least non-inferior to warfarin for efficacy and safety outcomes, controversy remains over the relative safety of each NOAC in patient subgroups. This narrative review provides an overview of phase III data on NOAC trials for the prevention of stroke in AF, with a focus on reporting the safety of each agent in key patient subgroups based on age, gender, accumulated risk factors, and primary or secondary prevention of stroke...
October 17, 2018: International Journal of Clinical Practice
Dirk Prochnau, Konstantin von Knorre, Hans-Reiner Figulla, P Christian Schulze, Ralf Surber
Background: We sought to evaluate a temperature-guided approach of cryoballoon (CB) ablation without visualization of real-time recordings. Methods and results: We analysed 166 patients (34.9% female, 60 ± 11 years) with paroxysmal or short-term persistent atrial fibrillation (AF). Comorbidities included diabetes mellitus (n = 28), coronary artery disease (n = 24), hypertension (n = 122), previous stroke or TIA > 3 months (n = 12)...
December 2018: IJC Heart & Vasculature
Cynthia Yeung, Doran Drew, Sharlene Hammond, Wilma M Hopman, Damian Redfearn, Christopher Simpson, Hoshiar Abdollah, Adrian Baranchuk
Atrial fibrillation (AF) is a risk factor for ischemic stroke and reported to be associated with severe obstructive sleep apnea (OSA). The aim of this study was to determine the occurrence of newly detected AF in patients with severe OSA and no previous history of AF. Prospective observational study included patients with severe OSA (Apnea-Hypopnea Index [AHI] ≥ 30) and no history of AF. Primary outcome was detection of AF lasting ≥10 seconds. Patients were subjected to 2 24-hour Holter monitors, and if no AF was detected, implanted with a Medtronic Reveal XT implantable loop recorder...
September 7, 2018: American Journal of Cardiology
Jennifer L Reed, Tasuku Terada, Daniele Chirico, Stephanie A Prince, Andrew L Pipe
BACKGROUND: Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is associated with substantial morbidity and mortality. Clinical guidelines for managing patients with AF do not include a referral to cardiac rehabilitation (CR) at present, although it is routine for most other cardiovascular conditions. The number of studies evaluating the impact of CR on the health of patients with AF is growing, but there has been no consolidation of the findings. The objective of this systematic review was to evaluate the impact of CR programs on physical and mental health outcomes in patients with all forms of AF...
October 2018: Canadian Journal of Cardiology
Yu-Yen Chen, Yung-Feng Yen, Jun-Xian Lin, Shih-Chao Feng, Li-Chen Wei, Yun-Ju Lai, Ying-Cheng Shen
Purpose: To investigate whether the risk of subsequent stroke, ischemic stroke, hemorrhagic stroke, and all-cause mortality is increased among retinal vein occlusion (RVO) patients compared to non-RVO patients. Methods: From the entire population of the Taiwan National Health Insurance Research Database (NHIRD) from 2001 to 2013, a total of 22919 subjects with RVO were enrolled in the RVO group, and 114595 propensity score (PS)-matched non-RVOs were enrolled in the comparison group...
2018: Journal of Ophthalmology
Victor A Abrich, Aalap D Narichania, William T Love, Louis A Lanza, Win-Kuang Shen, Dan Sorajja
PURPOSE: The purpose of this study was to determine whether surgical left atrial appendage (LAA) exclusion performed during mitral valve surgery is associated with a reduction in cerebrovascular events in patients with atrial fibrillation. METHODS: We retrospectively studied patients with atrial fibrillation who underwent mitral valve surgery from 1/1/2001 through 12/31/2014. We screened 1352 patients using ICD-9 codes and included 281 patients in the study. The primary end point was a composite of strokes and transient ischemic attacks occurring within 5 years after surgery...
September 28, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Bibijana Rostohar Bijelić, Marta Petek, Mira Kadojić, Nikola Bijelić, Dragutin Kadojić
The aim of this study was to determine the distribution of risk factors according to age, gender, subtypes and recurrence of stroke in eastern Croatia. The study included 250 acute stroke patients admitted to University Department of Neurology, Osijek University Hospital Centre in 2011. Patients were grouped according to age, gender, subtypes and recurrence of stroke. The study showed significant differences in the distribution of cigarette smoking, diabetes, cardiomyopathy and hyperuricemia according to patient age...
March 2018: Acta Clinica Croatica
Wei-Syun Hu, Cheng-Li Lin
The objective of the study was to explore the incidence of atrial fibrillation (AF) in various populations of patients with organ transplantation (OT). We used a large national data set from Taiwan to investigate the incidence of AF after OT. Frequency matching method used to match controls: OT patients were 4:1. Kaplan-Meier analyses with the use of the Aalen-Johansen estimator was employed for estimating the cumulative incidences of new-onset AF. The Fine-Gray competing risks model was also employed to analyze the risk of AF for the OT cohort compared with the non-OT cohort...
September 25, 2018: Internal and Emergency Medicine
Adam Ioannou, Nikolaos Papageorgiou, Donald Singer, Constantinos G Missouris
Background: Cardiovascular disease is the leading cause of morbidity and mortality in developed countries. Many patients do not experience symptoms before a first major cardiovascular event. Resting electrocardiogram (ECG) may help identify asymptomatic individuals with a high risk of cardiovascular disease. Objective: We sought to determine the prevalence of ECG abnormalities in an apparently symptom-free adult population within a prospective registry. Methods: The registry consisted of 4739 consecutive apparently healthy individuals (age 62...
September 20, 2018: QJM: Monthly Journal of the Association of Physicians
Michael H Kim, Liou Xu, Gary Puckrein
INTRODUCTION: Anticoagulants are effective for stroke prevention in atrial fibrillation (AF). Data on population health-related cardiovascular outcomes by race/ethnicity and gender are not well described. The aim was to assess the impact of patient diversity on associated cardiovascular outcomes related to warfarin anticoagulation in Medicare beneficiaries with AF. METHODS: Medicare administrative claims data for years 2000-2010 were used to calculate AF prevalence and rates of new AF cases...
September 15, 2018: Advances in Therapy
Anjani Golive, Heidi T May, Tami L Bair, Victoria Jacobs, Brian G Crandall, Michael J Cutler, John D Day, Charles Mallender, Jeffrey S Osborn, J Peter Weiss, T Jared Bunch
There are a paucity of data regarding the role of gender and atrial fibrillation (AF) on cognitive decline and incidence of dementia. Such data may provide insight into the disproportionate incidence of dementia in women and may help identify high-risk characteristics to target for prevention. We examined patients who underwent coronary angiography at an Intermountain Healthcare Medical Center and enrolled in a prospective cardiovascular database. To be included, patients could not have a previous diagnosis of AF or dementia and had to have 5 years of follow-up...
August 3, 2018: American Journal of Cardiology
Levent Cerit, Barçın Özcem, Zeynep Cerit, Hamza Duygu
OBJECTIVE: To assess the relationship between preoperative vitamin D (vitD) supplementation and the development of postoperative atrial fibrillation (POAF). METHODS: The study group consisted of 328 consecutive patients. The ınfluence of preoperative vitD supplementation on POAF was reviewed in 136 patients who underwent coronary artery bypass graft surgery with vitD insufficiency (n=80) and vitD deficiency (n=56). Patients were assigned to receive either oral vitD (50...
July 2018: Brazilian Journal of Cardiovascular Surgery
Mahmoud Hassanein, Magdy Abdelhamid, Bassem Ibrahim, Mohamed Sobhy, Gamela Nasr, Mohamed Wafaie Aboleineen, Ashraf Reda, Nabil Farag, Ahmed Elshazly, Tarek Khairy Abdeldayem, Fatma Elmesseiry, Hesham Boshra, Hesham Sobhy, Atef Elbahry, Amr Youssef, Medhat Ashmawy, Ahmed Abdelmoneim, Ayman Saleh, Yahya Elrakshy, Hamdy Ebeid
AIMS: This analysis evaluates gender differences in the Egyptian cohort of patients hospitalized for acute heart failure (AHF) in the European Society of Cardiology Heart Failure Long-Term Registry. METHODS AND RESULTS: From April 2011 to September 2014, 1634 patients hospitalized with AHF were enrolled by 20 hospitals all over Egypt. Of these patients, 1112 (68%) patients were male and 522 (32%) were female. Women presented with a higher admission systolic blood pressure and resting heart rate...
September 3, 2018: ESC Heart Failure
Tal Frenkel Rutenberg, Ran Rutenberg, Maria Vitenberg, Nir Cohen, Yichayaou Beloosesky, Steven Velkes
PURPOSE: To define risk factors for rehospitalization following fragility hip fractures and to create a predictive model. METHODS: A retrospective cohort study of patients 65 years and older, who were treated operatively following fragility hip fractures between 01.2011 and 06.2016. Patients were allocated into two study groups based on the occurrence of recurrent hospitalizations in the year following surgery. Demographic information, comorbidities, and in-hospital characteristics were collected, as was information regarding 1-year readmissions...
August 23, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
Yuji Murakawa, Teiichi Yamane, Masahiko Goya, Koichi Inoue, Shigeto Naito, Koichiro Kumagai, Yasushi Miyauchi, Norishige Morita, Akihiko Nogami, Morio Shoda, Ken Okumura, Kenzo Hirao
Background and purpose: In expectation of better outcome of catheter ablation of atrial fibrillation (AF), several strategies of extra-PV (pulmonary vein) substrate modification have been utilized. We assessed whether substrate modification or ablation of extra-PV source is a predictor of complications. Methods: Japanese Heart Rhythm Society requested electrophysiology centers to register the data of patients who underwent AF ablation. Results: The data of 10 795 AF ablation cases (age; 63...
August 2018: Journal of Arrhythmia
Pavel Overtchouk, Paul Guedeney, Stéphanie Rouanet, Jean Philippe Verhoye, Thierry Lefevre, Eric Van Belle, Helene Eltchaninoff, Martine Gilard, Pascal Leprince, Bernard Iung, Olivier Barthelemy, Hervé Le Breton, Géraud Souteyrand, Eric Vicaut, Gilles Montalescot, Jean-Philippe Collet
BACKGROUND: The optimal anti-thrombotic treatment after transcatheter aortic valve replacement (TAVR) remains a matter of debate. Dual antiplatelet therapy (DAPT) is recommended but single antiplatelet therapy or oral anticoagulation (OAC) are frequently used according to the patient profile. Whether this may impact clinical outcome is unknown. METHOD: and objectives: FRANCE-TAVI is a prospective multicenter nation-wide French registry. Our objectives were to identify independent correlates of long-term all-cause mortality and early bioprosthetic valve dysfunction (BVD, defined as increased prosthetic gradient ≥10 mmHg or new gradient ≥20 mmHg)...
August 22, 2018: Journal of the American College of Cardiology
Gregory Y H Lip, Amitava Banerjee, Giuseppe Boriani, Chern En Chiang, Ramiz Fargo, Ben Freedman, Deirdre A Lane, Christian T Ruff, Mintu Turakhia, David Werring, Sheena Patel, Lisa Moores
BACKGROUND: The risk of stroke is heterogeneous across different groups of patients with atrial fibrillation (AF), being dependent on the presence of various stroke risk factors. We provide recommendations for antithrombotic treatment based on net clinical benefit for patients with AF at varying levels of stroke risk and in a number of common clinical scenarios. METHODS: Systematic literature reviews were conducted to identify relevant articles published from the last formal search perfomed for the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (9th Edition)...
August 22, 2018: Chest
Attila Nemes, Dóra Földeák, Péter Domsik, Anita Kalapos, Árpád Kormányos, Zita Borbényi, Tamás Forster
BACKGROUND: Light-chain (AL) cardiac amyloidosis (CA) is characterized by fibril deposits, which are composed of monoclonal immunoglobulin light chains. The right ventricle is mostly involved in AL-CA and impairment of its function is a predictor of worse prognosis. OBJECTIVES: To characterize the volumetric and functional properties of the right atrium (RA) in AL-CA by three-dimensional speckle-tracking echocardiography (3DSTE). METHODS: A total of 16 patients (mean age: 64...
August 20, 2018: Arquivos Brasileiros de Cardiologia
William Hinton, Andrew McGovern, Rachel Coyle, Thang S Han, Pankaj Sharma, Ana Correa, Filipa Ferreira, Simon de Lusignan
OBJECTIVES: To describe incidence and prevalence of cardiovascular disease (CVD), its risk factors, medication prescribed to treat CVD and predictors of CVD within a nationally representative dataset. DESIGN: Cross-sectional study of adults with and without CVD. SETTING: The Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) is an English primary care sentinel network. RCGP RSC is over 50 years old and one of the oldest in Europe...
August 20, 2018: BMJ Open
Yu Zhang, Peifei Li, Min Miao, Yi Liu, Yue Pan, Lu Xu, Zhongwei Zhu, Chengfu Xu, Lei Xu
Background: Atrial fibrillation and nonalcoholic fatty liver disease are two pathological conditions that are highly prevalent worldwide and share multiple CVD risk factors. There are rare researches performed among elderly adults. Aims: We conducted this cross-sectional analysis of elderly adults (≥65 years) to investigate the association between atrial fibrillation and nonalcoholic fatty liver disease. Methods: We analyzed clinical data of the elderly adults (≥ 65 years) who had health examination in Zhenhai Lianhua Hospital, Ningbo, China, in 2014...
2018: BioMed Research International
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