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Atrial Fibrillation And Gender

Ko Eun Kim, Pil Sung Yang, Eunsun Jang, Sungjin Kim, Boyoung Joung
PURPOSE: Antithrombotic therapy could be related with nuisance bleeding. This study investigated whether vitreous hemorrhage (VH) is associated with specific types of antithrombotic medication in patients with atrial fibrillation (AF). MATERIALS AND METHODS: In the Korean National Health Insurance Service National Sample Cohort, we identified 9352 antiplatelet/anticoagulant-treated AF patients. The occurrence of VH was compared between warfarin (n=1493) and a propensity score (PS)-matched antiplatelet group (n=1493) and between warfarin (n=1493) and a PS-matched warfarin+antiplatelet group (n=1493)...
January 2019: Yonsei Medical Journal
Taylor C Bazemore, Lauren E Bolger, Samuel F Sears, Murrium I Sadaf, Anil K Gehi
BACKGROUND: Catheter ablation improves symptoms and quality of life in patients with atrial fibrillation (AF); however, despite its benefit, women are less likely than men to undergo catheter ablation. Women with AF have been described to have more frequent and severe symptoms with a lower quality of life than men, and it is therefore unclear why women are less likely to undergo catheter ablation. We prospectively characterized gender differences in AF symptoms among men and women undergoing ablation at UNC using questionnaire data...
December 13, 2018: Pacing and Clinical Electrophysiology: PACE
Neshro Barmano, Emmanouil Charitakis, Jan-Erik Karlsson, Fredrik H Nystrom, Håkan Walfridsson, Ulla Walfridsson
BACKGROUND: The primary goal of radiofrequency ablation (RFA) of atrial fibrillation (AF) is to improve symptoms and HRQoL. However, most studies have focused on predictors of AF recurrence rather than on predictors of improvement in symptoms and HRQoL. HYPOTHESIS: We sought to explore predictors of improvement in arrhythmia-specific symptoms and health-related quality of life (HRQoL) after RFA of AF, and to evaluate the effects on symptoms, HRQoL, anxiety and depression...
December 11, 2018: Clinical Cardiology
Xiangdan Li, Songbiao Cui, Dongchun Xuan, Chunhua Xuan, Dongyuan Xu
BACKGROUND: Atrial fibrillation (AF) is the most common type of heart arrhythmia, but the impact of long-term, high-intensity endurance exercise on the risk of AF remains uncertain. METHODS: PubMed, EMBASE, and Cochrane library databases were searched till Nov 2017 to retrieve the articles. The included studies were summarized, pooled odds ratio (OR) and its 95% confidence interval (CI) were calculated. Both fixed and random effects models were used to combine the data...
December 2018: Medicine (Baltimore)
Sean M Caples, Meghna P Mansukhani, Paul A Friedman, Virend K Somers
BACKGROUND: Observational data suggest that positive airway pressure (PAP) treatment of obstructive sleep apnea (OSA) can reduce the risk of recurrent atrial fibrillation (AF) post-direct current cardioversion (DCCV) or catheter ablation. METHODS: We conducted a study of adult patients with AF and sleep apnea, stratified by age and gender, who underwent successful DCCV to sinus rhythm, and who were randomized to receive PAP or usual care. Those with sleepiness, significant cardiac or respiratory disease were excluded...
November 20, 2018: International Journal of Cardiology
Stacy Westerman, Nanette Wenger
Atrial fibrillation is the most common sustained cardiac arrhythmia. The scope and impact of atrial fibrillation is wide; it can affect cardiac function, functional status, and quality of life, and it confers a stroke risk. There are sex differences in atrial fibrillation across the scope of the disease process, from epidemiology and causative mechanisms to management and outcomes. The approach to management of atrial fibrillation differs between women and men, and there are sex differences in response to medical therapy and catheter ablation...
December 4, 2018: Current Cardiology Reviews
Marwan Sheikh-Taha, Hani Dimassi
BACKGROUND: In recent years there has been a substantial increase in the use of over-the-counter (OTC) products around the world. While they are assumed to be safe by consumers, they can potentially lead to adverse effects and drug interactions particularly in older adults. METHODS: We assessed the patterns of OTC products used by older adults admitted to the cardiology service in a tertiary care medical center in the USA over a three month period. We conducted a retrospective chart review where older adults with cardiovascular diseases (CVD) who were taking at least one OTC product at home were included...
December 4, 2018: BMC Geriatrics
Heather Smith, Ching Yeung, Stephen Gowing, Mouhannad Sadek, Donna Maziak, Sebastien Gilbert, Farid Shamji, Patrick Villeneuve, Sudhir Sundaresan, Andrew Seely
Atrial fibrillation (AF) is the most common sustained arrhythmia after non-cardiac thoracic surgery and is associated with a significant increase in perioperative morbidity, intensive care unit (ICU) admission, and mortality. Practical guidance is needed to assist clinicians in managing this critical issue and direct further research. Here we aim to provide a synoptic review and analysis of the literature to distil practical recommendations for prediction, prevention and management of post-operative atrial fibrillation (POAF) suitable for clinical application and further evaluation...
November 2018: Journal of Thoracic Disease
Younghoon Kwon, Sneha Gadi, Neil R Shah, Christopher Stout, Jacob N Blackwell, Yeilim Cho, Ryan J Koene, Nishaki Mehta, Sula Mazimba, Andrew E Darby, John D Ferguson, Kenneth C Bilchick
Background: Self-reported poor sleep quality has been suggested in patients with AF. Slow wave sleep (SWS) is considered the most restorative sleep stage and represents an important objective measure of sleep quality. The aim of this study was to compare quantity of SWS between patients with and without AF. Methods and Results: We included patients with and without a documented history of AF by reviewing clinically indicated polysomnography data from a single sleep center...
August 2018: Journal of Atrial Fibrillation
Masanari Kuwabara, Ichiro Hisatome
No abstract text is available yet for this article.
November 30, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
Patrick Blin, Caroline Dureau-Pournin, Yves Cottin, Jacques Bénichou, Patrick Mismetti, Abdelilah Abouelfath, Regis Lassalle, Cécile Droz, Nicholas Moore
Dabigatran and rivaroxaban at standard (SD) or reduced doses (RD) have been compared to warfarin in non-valvular atrial fibrillation (NVAF), but not to each other. This was a new user study of SD and RD dabigatran or rivaroxaban for NVAF in the French healthcare database, matched on gender, age, date of first dispensing, and high-dimensional propensity score, followed 2 years. Hazard ratios [95% Confidence Intervals] of stroke or systemic embolism (SSE), major bleeding (MB) or death, were computed. In matched SD patients (8,290 per arm), mean age 67, HR for dabigatran vs...
November 30, 2018: Clinical Pharmacology and Therapeutics
Jelena Kornej, Petra Büttner, Elke Hammer, Beatrice Engelmann, Borislav Dinov, Philipp Sommer, Daniela Husser, Gerhard Hindricks, Uwe Völker, Andreas Bollmann
BACKGROUND: Left atrial (LA) electro-anatomical remodeling and diameter increase in atrial fibrillation (AF) indicates disease progression and is associated with poor therapeutic success. Furthermore, AF leads to a hypercoagulable state, which in turn promotes the development of a substrate for AF and disease progression in the experimental setting. The aim of this study was to identify pathways associated with LA remodeling in AF patients using untargeted proteomics approach. METHODS: Peripheral blood samples of 48 patients (62±10 years, 63% males, 59% persistent AF) undergoing AF catheter ablation were collected before ablation...
2018: PloS One
Mario Bo, Alice Ceccofiglio, Chiara Mussi, Giuseppe Bellelli, Franco Nicosia, Daniela Riccio, Anna M Martone, Assunta Langellotto, Elisabetta Tonon, Gianni Tava, Virginia Boccardi, Pasquale Abete, Michela Tibaldi, Maria L Aurucci, Gianfranco Fonte, Yolanda Falcone, Andrea Ungar
BACKGROUND: Long QT and use of QT-prolonging drugs are common among older patients receiving polytherapies, but real-world evidence on their impact in clinical practice is controversial. We investigated prevalence, variables associated and clinical implications of prolonged corrected QT (QTc) among patients from the Syncope and Dementia study. METHODS: Observational, prospective, multicenter study. Patients≥65 years with dementia and fall suspected for syncope in the previous three months were enrolled...
October 25, 2018: European Journal of Internal Medicine
Luke Lam, Hyeong Jun Ahn, Kazue Okajima, Katie Schoenman, Todd B Seto, Ralph V Shohet, Jill Miyamura, Tetine L Sentell, Kazuma Nakagawa
BACKGROUND: It has been reported that women have higher 30-day readmission rates than men after acute coronary syndrome (ACS). However, readmission after percutaneous coronary intervention (PCI) for ACS is a distinct subset of patients in whom gender differences have not been adequately studied. METHODS: Hawaii statewide hospitalization data from 2010 to 2015 were assessed to compare gender differences in 30-day readmission rates among patients hospitalized with ACS who underwent PCI during the index hospitalization...
October 25, 2018: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
Matthew Lewis, William Whang, Angelo Biviano, Kathleen Hickey, Hasan Garan, Marlon Rosenbaum
BACKGROUND: Catheter ablation is commonly performed to treat atrial arrhythmias in adult congenital heart disease (ACHD). Despite the frequency of ablations in the ACHD population, predictors of recurrence remain poorly defined. OBJECTIVE: We sought to determine predictors of arrhythmia recurrence in ACHD patients following catheter ablation for atrial arrhythmias. METHODS: We performed a retrospective study of all catheter ablations for atrial arrhythmias performed in ACHD patients between January 12, 2005 and February 11, 2015 at our institution...
November 19, 2018: Congenital Heart Disease
Hidehiro Kaneko, Frank Hoelschermann, Grit Tambor, Maki Okamoto, Michael Neuss, Christian Butter
N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels prior to transcatheter aortic valve implantation (TAVI) are known to be associated with outcomes of patients undergoing TAVI. However, little has been known about the NT-proBNP response after TAVI. Therefore, we aimed to clarify the role of the NT-proBNP response and identify the determinants of the NT-proBNP nonresponse among patients with severe aortic stenosis (AS) and heart failure (HF) undergoing TAVI. We examined 717 patients with severe AS and HF undergoing TAVI...
November 15, 2018: Heart and Vessels
Xingjie Li, Jing Yu, Wenjuan Huang, Qi Huang, Jun Yan, Huaping Liang, Yu Sun
OBJECTIVE: To investigate the risk factors of acute respiratory distress syndrome (ARDS) occurrence in intensive care unit (ICU) traumatic patients. METHODS: Clinical data of traumatic patients in ICU of the People's Hospital of Liangping in Chongqing from January 1st, 2012 to June 30th, 2018 were retrospectively analyzed. According to the outcomes, the patients were divided into ARDS group and non-ARDS group. The differences of demographic indexes (gender, age), time of admission, type of injury, atrial fibrillation, trachea cannula, multiple injury, open injury, shock, surgery, blood transfusion, central venous indwelling catheter, infection, and blood routine indexes [white blood cell count (WBC), red blood cell count (RBC), platelet count (PLT), plateletcytocrit (PCT), hematocrit (Hct)], biochemical indexes [total bilirubin (TBil), albumin (Alb), serum creatinine (SCr), blood sodium, blood calcium, blood potassium, blood glucose], arterial blood gas analysis indexes [partial pressure of carbon dioxide (PaCO2 ), partial pressure of oxygen (PaO2 ), oxygenation index (PaO2 /FiO2 ), blood pH], coagulation indicators [activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT), international normalized ratio (INR), fibrinogen (Fib)], injury severity score (ISS), new injury severity score (NISS), acute physiology and chronic health evaluation II (APACHE II), sequential organ failure assessment (SOFA), Glasgow coma scale (GCS) within 24 hours of admission, and the length of ICU stay between the two groups were analyzed, and the possible influencing factors were screened out...
October 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
Illa Mihejeva, Anita Vētra, Guna Bērziņa
AIM: The aim of this study was to evaluate how pre-stroke risk factors, neurological symptoms, and the level of disability shortly after stroke are associated with poststroke mortality during a 7-year period after stroke, for persons treated in a stroke unit. METHODS: The data of 231 patients were included in the study. Patients who were treated in the stroke unit at the Riga East University Hospital between February 1, 2009, and July 20, 2009, were included in this study...
November 12, 2018: Brain and Behavior
Li-Rui You, Mei Tang
This study aimed to explore the relationship of D-dimer level with the risk stratification of ischemic stroke, and determine whether high D-dimer levels could be used as a risk factor of ischemic stroke in patients with nonvalvular atrial fibrillation (NVAF).This single-center, retrospective study recruited NVAF patients who did not undergo anticoagulant therapy. These patients were divided into 2 groups: ischemic stroke group and no-stroke group. The medical records of each patient were reviewed, demographic and clinical analyses were performed, and the laboratory results were summarized...
October 2018: Medicine (Baltimore)
Jerzy Piwoński, Aleksandra Piwońska, Piotr Jędrusik, Jakub Stokwiszewski, Marcin Rutkowski, Piotr Bandosz, Wojciech Drygas, Tomasz Zdrojewski
BACKGROUND: Poland is a country of high cardiovascular risk. Because the depression was found to be a predictor of coronary artery disease and the prevalence of depressive symptoms raised worldwide, so the monitoring of depressive symptoms in a population is desirable. AIM: to evaluate the prevalence of depressive symptoms (DS) in relation to the socio-demographic status, and selected types of cardiovascular diseases in the adult Polish population. METHODS: A country representative random sample of 2413 subjects, aged 18-79, was examined in 2011...
November 8, 2018: Kardiologia Polska
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