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https://www.readbyqxmd.com/read/27900083/primary-malignant-pericardial-mesothelioma-with-increased-serum-mesothelin-diagnosed-by-surgical-pericardial-resection-a-case-report
#1
Takeyuki Kurosawa, Keishi Sugino, Kazutoshi Isobe, Yoshinobu Hata, Yuri Fukasawa, Sakae Homma
A 37-year-old female smoker without a history of exposure to asbestos was referred to our hospital with persistent pericardial effusion. Chest computed tomography imaging examination revealed an irregular thickened pericardium with large amounts of pericardial effusion and a small pleural effusion. Fluorodeoxyglucose (FDG) positron emission tomography imaging demonstrated intrapericardial FDG accumulation. Blood tests revealed an increase in serum mesothelin levels. Examination of a surgically resected specimen revealed a grayish-white thickening of the pericardium, with a straw-colored mucinous pericardial effusion...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27894541/assessment-of-the-changes-in-arch-perimeter-and%C3%A2-irregularity-in-the-mandibular-arch-during-initial-alignment-with-the-acceledent-aura-appliance-vs-no-appliance-in-adolescents-a-single-blind-randomized-clinical-trial
#2
Peter Miles, Elizabeth Fisher
INTRODUCTION: The purpose of this 2-arm parallel trial was to assess the effects of the AcceleDent Aura (OrthoAccel Technologies, Houston, Tex) appliance on the increase in mandibular anterior arch perimeter, the reduction in mandibular arch irregularity, and the amount of discomfort during initial alignment of the mandibular arch with fixed appliances. METHODS: Forty Class II adolescent patients with full fixed appliances and treated with maxillary premolar extractions and no extractions in the mandibular arch participated in this randomized clinical trial...
December 2016: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27875936/characterization-of-dust-from-blast-furnace-cast-house-de-dusting
#3
Christof Lanzerstorfer
During casting of liquid iron and slag a considerable amount of dust is emitted into the cast house of a blast furnace. Usually, this dust is extracted via exhaust hoods and subsequently separated from the ventilation air. In most blast furnaces the cast house dust is recycled. In this study a sample of cast house dust was split by air classification into five size fractions which were then analysed. Micrographs showed that the dominating particle type in all size fractions is that of single spherical-shaped particles...
November 23, 2016: Environmental Technology
https://www.readbyqxmd.com/read/27875321/the-impact-of-selected-environmental-behavioral-and-psychosocial-factors-on-schoolchildren-s-somatic-and-mental-health
#4
Diana Vondrova, Daniela Kapsdorfer, Lubica Argalasova, Katarina Hirosova, Martin Samohyl, Ludmila Sevcikova
Children develop rapidly and many exogenous determinants of health significantly affect their somatic and mental development. There is a subjective perception of cognitive load associated with the educational process. The aim of the study is to assess individual environmental, behavioral and psychosocial factors influencing physical health and to investigate the amount of mental load in children. We investigated 87 schoolchildren (47 girls and 40 boys) aged 10-12 years, who were attending primary school in Bratislava...
November 22, 2016: Reviews on Environmental Health
https://www.readbyqxmd.com/read/27870066/a-nonnative-and-a-native-fungal-plant-pathogen-similarly-stimulate-ectomycorrhizal-development-but-are-perceived-differently-by-a-fungal-symbiont
#5
Elisa Zampieri, Luana Giordano, Guglielmo Lione, Alfredo Vizzini, Fabiano Sillo, Raffaella Balestrini, Paolo Gonthier
The effects of plant symbionts on host defence responses against pathogens have been extensively documented, but little is known about the impact of pathogens on the symbiosis and if such an impact may differ for nonnative and native pathogens. Here, this issue was addressed in a study of the model system comprising Pinus pinea, its ectomycorrhizal symbiont Tuber borchii, and the nonnative and native pathogens Heterobasidion irregulare and Heterobasidion annosum, respectively. In a 6-month inoculation experiment and using both in planta and gene expression analyses, we tested the hypothesis that H...
November 21, 2016: New Phytologist
https://www.readbyqxmd.com/read/27856710/differences-in-glycosyltransferase-family-61-accompany-variation-in-seed-coat-mucilage-composition-in-plantago-spp
#6
Jana L Phan, Matthew R Tucker, Shi Fang Khor, Neil Shirley, Jelle Lahnstein, Cherie Beahan, Antony Bacic, Rachel A Burton
Xylans are the most abundant non-cellulosic polysaccharide found in plant cell walls. A diverse range of xylan structures influence tissue function during growth and development. Despite the abundance of xylans in nature, details of the genes and biochemical pathways controlling their biosynthesis are lacking. In this study we have utilized natural variation within the Plantago genus to examine variation in heteroxylan composition and structure in seed coat mucilage. Compositional assays were combined with analysis of the glycosyltransferase family 61 (GT61) family during seed coat development, with the aim of identifying GT61 sequences participating in xylan backbone substitution...
December 2016: Journal of Experimental Botany
https://www.readbyqxmd.com/read/27856455/map3k8-modulates-monocyte-state-and-atherogenesis-in-apoe-mice
#7
Carlos Sanz-Garcia, Ángela Sánchez, Constanza Contreras-Jurado, Carmela Cales, Cristina Barranquero, Marta Muñóz, Ramón Merino, Paula Escudero, Maria-Jesús Sanz, Jesús Osada, Ana Aranda, Susana Alemany
OBJECTIVE: Map3k8 (Cot/Tpl2) activates the MKK1/2-ERK1/2, MAPK pathway downstream from interleukin-1R, tumor necrosis factor-αR, NOD-2R, adiponectinR, and Toll-like receptors. Map3k8 plays a key role in innate and adaptive immunity and influences inflammatory processes by modulating the functions of different cell types. However, its role in atherogenesis remains unknown. In this study, we analyzed the role of this kinase in this pathology. APPROACH AND RESULTS: We show here that Map3k8 deficiency results in smaller numbers of Ly6C(high)CD11c(low) and Ly6C(low)CD11c(high) monocytes in ApoE(-)(/-) mice fed a high-fat diet (HFD)...
November 17, 2016: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/27842537/siberian-flying-squirrels-do-not-anticipate-future-resource-abundance
#8
Vesa Selonen, Ralf Wistbacka
BACKGROUND: One way to cope with irregularly occurring resources is to adjust reproduction according to the anticipated future resource availability. In support of this hypothesis, few rodent species have been observed to produce, after the first litter born in spring, summer litters in anticipation of autumn's seed mast. This kind of behaviour could eliminate or decrease the lag in population density normally present in consumer dynamics. We focus on possible anticipation of future food availability in Siberian flying squirrels, Pteromys volans...
November 14, 2016: BMC Ecology
https://www.readbyqxmd.com/read/27826935/modified-krimsky-test-for-irregular-scarred-corneas
#9
Harindersingh Sethi, Mayuresh Naik, Mukesh Joshi
The measurement of the amount and nature of deviation is the essence of diagnostic workup of a patient with strabismus and also has important therapeutic implications while planning the amount of surgery or prescribing therapeutic prisms. Although Krimsky test is a useful method, it cannot be used to measure deviation in patients with scarred and irregular cornea with an anechoic posterior segment making it difficult to see the corneal reflex. We hereby take the opportunity to present a modification of the original Krimsky test which is extremely helpful in determining the deviation in patients with irregular opaque corneas...
November 8, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27807679/anammox-zeolite-system-acting-as-buffer-to-achieve-stable-effluent-nitrogen-values
#10
Kozet Yapsakli, Cigdem Kalkan Aktan, Bulent Mertoglu
For a successful nitrogen removal, Anammox process needs to be established in line with a stable partial nitritation pretreatment unit since wastewater influent is mostly unsuitable for direct treatment by Anammox. Partial nitritation is, however, a critical bottleneck for the nitrogen removal since it is often difficult to maintain the right proportions of NO2-N and NH4-N during long periods of time for Anammox process. This study investigated the potential of Anammox-zeolite biofilter to buffer inequalities in nitrite and ammonium nitrogen in the influent feed...
November 2, 2016: Biodegradation
https://www.readbyqxmd.com/read/27792754/characterization-of-zebrafish-models-of-marinesco-sj%C3%A3-gren-syndrome
#11
Genri Kawahara, Yukiko K Hayashi
SIL1 is a nucleotide exchange factor for the endoplasmic reticulum chaperone, BiP. Mutations in the SIL1 gene cause Marinesco-Sjögren syndrome (MSS), an autosomal recessive disease characterized by cerebellar ataxia, mental retardation, congenital cataracts, and myopathy. To create novel zebrafish models of MSS for therapeutic drug screening, we analyzed phenotypes in sil1 knock down fish by two different antisense oligo morpholinos. Both sil1 morphants had abnormal formation of muscle fibers and irregularity of the myosepta...
2016: PloS One
https://www.readbyqxmd.com/read/27776520/anatomical-study-of-the-coracoid-process-in-mongolian-male-cadavers-using-the-latarjet-procedure
#12
Jianqiang Lian, Lele Dong, Yanjun Zhao, Jinlei Sun, Wenlong Zhang, Chunzheng Gao
BACKGROUND: The Latarjet procedure addresses recurrent anterior shoulder instability in the context of a significant bony defect. However, the bony and soft tissue anatomy of the coracoid in coracoid transfer procedures has not yet been defined in Mongolian men. The aims of this study were to describe the soft tissue attachments of the coracoid regarding the bony anatomy, define the average amount of bone available for coracoid transfer, analyze the characteristics of the pectoralis minor and coracoid, and study the relationship between the bony dimensions of the coracoid and body length in Mongolian men...
October 24, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27754282/hw-04-3-global-network-for-her-based-big-data-analysis
#13
Peter Rijnbeek
Massive numbers of electronic health records are currently being collected globally, including structured data in the form of diagnoses, medications, laboratory test results, and unstructured data contained in clinical narratives. This opens unprecedented possibilities for research and ultimately patient care. However, actual use of these databases in a multi-center study is severely hampered by a variety of challenges, e.g., each database has a different database structure and uses different terminology systems...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27701128/histogram-planimetry-method-for-the-measurement-of-irregular-wounds
#14
Nebil Yesiloglu, Kemalettin Yildiz, Ali Cem Akpinar, Tahsin Gorgulu, Hakan Sirinoglu, Arzu Ozcan
INTRODUCTION: Irregularly shaped wounds or flap borders usually require specified software or devices to measure their area and follow-up wound healing. In this study, an easy way of area measurement called histogram planimetry (HP) for wounds with irregular geometric shapes is defined and compared to conventional millimetric wound measurement. MATERIALS AND METHODS: Ten irregularly bordered geometric shapes were measured by 4 different individuals working as surgical assistants using both HP and manual millimetric measurement tools...
September 2016: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/27685505/controversies-with-self-emulsifying-drug-delivery-system-from-pharmacokinetic-point-of-view
#15
Bappaditya Chatterjee, Samah Hamed Almurisi, Ather Ahmed Mahdi Dukhan, Uttam Kumar Mandal, Pinaki Sengupta
Self-emulsifying drug delivery system (SEDDS) is an isotropic mixture of lipid, surfactant and co-surfactant, which forms a fine emulsion when comes in contact of an aqueous medium with mild agitation. SEDDS is considered as a potential platform for oral delivery of hydrophobic drug in order to overcome their poor and irregular bioavailability challenges. In spite of fewer advantages like improved solubility of drug, bypassing lymphatic transport etc., SEDDS faces different controversial issues such as the use of appropriate terminology (self-microemulsifying drug delivery system; SMEDDS or self-nanoemulsifying drug delivery system; SNEDDS), presence of high amount of surfactant, correlation of in vitro model to in vivo studies, lack of human volunteer study and effect of conversion of SEDDS to final administrable dosage form on pharmacokinetic behavior of the drug...
November 2016: Drug Delivery
https://www.readbyqxmd.com/read/27680498/observation-on-the-ultrastructure-morphology-of-hela-cells-treated-with-ethanol-statistical-analysis
#16
Fakhri Al-Bagdadi, Matthew J Young, James P Geaghan, Shaomian Yao, Humberto M Barona, Eduardo Martinez-Ceballos, Masami Yoshimura
It is estimated that 5.9% of all human deaths are attributable to alcohol consumption and that the harmful use of ethanol ranks among the top five risk factors for causing disease, disability, and death worldwide. Ethanol is known to disrupt phospholipid packing and promote membrane hemifusion at lipid bilayers. With the exception of mitochondria involved in hormone synthesis, the sterol content of mitochondrial membranes is low. As membranes that are low in cholesterol have increased membrane fluidity and are the most easily disordered by ethanol, we hypothesize that mitochondria are sensitive targets for ethanol damage...
November 2016: Ultrastructural Pathology
https://www.readbyqxmd.com/read/27678084/evaluating-google-flu-trends-in-latin-america-important-lessons-for-the-next-phase-of-digital-disease-detection
#17
S Pollett, W J Boscardin, E Azziz-Baumgartner, Y O Tinoco, G Soto, C Romero, J Kok, M Biggerstaff, C Viboud, G W Rutherford
BACKGROUND:  Latin America has a substantial burden of influenza and rising Internet access and could thus benefit from real-time influenza epidemic prediction web-tools such as Google Flu Trends (GFT) to assist in risk communication and resource allocation during epidemics. However, there has never been a published assessment of GFT's accuracy in most of the Latin American countries nor in any low-middle income country. We aimed to evaluate GFT in Argentina, Bolivia, Brazil, Chile, Mexico, Paraguay, Peru and Uruguay...
September 26, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27643279/hw-04-3-global-network-for-her-based-big-data-analysis
#18
Peter Rijnbeek
Massive numbers of electronic health records are currently being collected globally, including structured data in the form of diagnoses, medications, laboratory test results, and unstructured data contained in clinical narratives. This opens unprecedented possibilities for research and ultimately patient care. However, actual use of these databases in a multi-center study is severely hampered by a variety of challenges, e.g., each database has a different database structure and uses different terminology systems...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27622643/the-progeroid-gene-bubr1-regulates-axon-myelination-and-motor-function
#19
Chan-Il Choi, Ki Hyun Yoo, Syed Mohammed Qasim Hussaini, Byeong Tak Jeon, John Welby, Haiyun Gan, Isobel Scarisbrick, Zhiguo Zhang, Darren J Baker, Jan M van Deursen, Moses Rodriguez, Mi-Hyeon Jang
Myelination, the process by which oligodendrocytes form the myelin sheath around axons, is key to axonal signal transduction and related motor function in the central nervous system (CNS). Aging is characterized by degenerative changes in the myelin sheath, although the molecular underpinnings of normal and aberrant myelination remain incompletely understood. Here we report that axon myelination and related motor function are dependent on BubR1, a mitotic checkpoint protein that has been linked to progeroid phenotypes when expressed at low levels and healthy lifespan when overabundant...
September 12, 2016: Aging
https://www.readbyqxmd.com/read/27608426/designing-of-silk-and-zno-based-antibacterial-and-noncytotoxic-bionanocomposite-films-and-study-of-their-mechanical-and-uv-absorption-behavior
#20
Anamika Kiro, Jaya Bajpai, A K Bajpai
Bionanocomposites of sericin and polyvinyl alcohol (PVA) were prepared by solution casting method and zinc oxide nanoparticles were impregnated within the polymer blend matrix through homogenous phase reaction between zinc chloride and sodium hydroxide at high temperature following an ex-situ co-precipitation method. The prepared bionanocomposites were characterized using Fourier Transform Infrared Spectroscopy, X-ray diffraction, Field Emission Scanning Electron Microscopy, Transmission Electron Microscopy and Atomic Force Microscopy techniques...
August 26, 2016: Journal of the Mechanical Behavior of Biomedical Materials
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