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Biomechanical analysis of anterior cervical fusion

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https://www.readbyqxmd.com/read/28989848/biomechanical-stability-of-a-stand-alone-interbody-spacer-in-two-level-and-hybrid-cervical-fusion-constructs
#1
Daniel G Kang, Scott C Wagner, Robert W Tracey, John P Cody, Rachel E Gaume, Ronald A Lehman
STUDY DESIGN: In vitro human cadaveric biomechanical analysis. OBJECTIVE: To evaluate the segmental stability of a stand-alone spacer (SAS) device compared with the traditional anterior cervical plate (ACP) construct in the setting of a 2-level cervical fusion construct or as a hybrid construct adjacent to a previous 1-level ACP construct. METHODS: Twelve human cadaveric cervical spines (C2-T1) were nondestructively tested with a custom 6-degree-of-freedom spine simulator under axial rotation (AR), flexion-extension (FE), and lateral bending (LB) at 1...
October 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28960818/biomechanical-stability-analysis-of-a-stand-alone-cage-static-and-rotational-dynamic-plate-in-a-two-level-cervical-fusion-construct
#2
Parmenion P Tsitsopoulos, Leonard I Voronov, Michael R Zindrick, Gerard Carandang, Robert M Havey, Alexander J Ghanayem, Avinash G Patwardhan
OBJECTIVE: To test the following hypotheses: (i) anterior cervical discetomy and fusion (ACDF) using stand-alone interbody spacers will significantly reduce the range of motion from intact spine; and (ii) the use of a static or a rotational-dynamic plate will significantly augment the stability of stand-alone interbody spacers, with similar beneficial effect when compared to each other. METHODS: Eleven human cadaveric subaxial cervical spines (age: 48.2 ± 5.4 years) were tested under the following sequence: (i) intact spine; (ii) ACDF at C4 -C5 using a stand-alone interbody spacer; (iii) ACDF at C5 -C6 and insertion of an interbody spacer (two-level construct); and (iv) randomized placement of either a two-level locking static plate or a rotational-dynamic plate...
August 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28835868/anterior-cervical-discectomy-with-fusion-using-a-local-source-for-cancellous-autograft-a-biomechanical-analysis-of-vertebral-body-stability-in-an-osteopenic-bone-model
#3
Zakk Walterscheid, Conor O'Neill, Alex Ochs, Adrian D'Averso, Christopher Dew, Alyssa Huntington, Grace Ma, Caleb Behrend, Rafaella De Vita, Jonathan Carmouche
BACKGROUND: Anterior cervical discectomy with fusion is an effective treatment for patients having cervical radiculopathy and myelopathy. To reduce morbidity associated with autograft taken from the iliac crest without sacrificing high fusion rates, a novel technique that harvests bone from the vertebral body adjacent to the operative disc space has been proposed. The effects of square and round bone graft harvest techniques on the mechanical stability of the osteopenic donor vertebrae are unknown...
September 2017: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/28736113/titanium-vs-polyetheretherketone-peek-interbody-fusion-meta-analysis-and-review-of-the-literature
#4
REVIEW
Scott Seaman, Panagiotis Kerezoudis, Mohamad Bydon, James C Torner, Patrick W Hitchon
Spinal interbody fusion is a standard and accepted method for spinal fusion. Interbody fusion devices include titanium (Ti) and polyetheretherketone (PEEK) cages with distinct biomechanical properties. Titanium and PEEK cages have been evaluated in the cervical and lumbar spine, with conflicting results in bony fusion and subsidence. Using Preferred Reporting Items for Systematic reviews and Meta-analyses (PRISMA) guidelines, we reviewed the available literature evaluating Ti and PEEK cages to assess subsidence and fusion rates...
October 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28589409/application-of-biodegradable-3d-printed-cage-for-cervical-diseases-via-anterior-cervical-discectomy-and-fusion-acdf-an-in-vitro-biomechanical-study
#5
Xiaofan Yin, Libo Jiang, Jielai Yang, Lu Cao, Jian Dong
OBJECTIVES: To design and fabricate a 3D-printed cervical cage composite of polylactic acid (PLA)/nano-sized and β-tricalcium phosphate (β-TCP). RESULTS: CAD analysis provided a useful platform to design the preliminary cage. In vitro cell culture and in vivo animal results showed promising results in the biocompatibility of the constructs. Endplate matching evaluation showed better matching degree of 3D-printed cages than those of conventional cages. Biomechanical evaluation showed better mechanical properties of 3D-printed cages than those of conventional cages...
June 6, 2017: Biotechnology Letters
https://www.readbyqxmd.com/read/28408260/evaluation-of-bioabsorbable-multiamino-acid-copolymer-nanohydroxyapatite-calcium-sulfate-cage-in-a-goat-spine-model
#6
Chunpeng Ren, Yueming Song, Youdi Xue, Xi Yang, Chunguang Zhou
BACKGROUND: Currently, polylactide is the most popular material used to made bioabsorbable cages but too-quick degradation and osteolysis around the cage have been reported in the literature. This study evaluated the fusion effect, biomechanical stability, and histologic characteristics of a novel bioabsorbable multiamino acid copolymer/nanohydroxyapatite/calcium sulfate (MAACP/n-HA/CS) interbody cage in a goat model of anterior cervical discectomy and fusion. METHODS: A total of 24 goats underwent C3/C4 discectomy and fusion with 3 groups of intervertebral implants: MAACP/n-HA/CS cage group (n = 8), titanium cage group (n = 8), and autologous tricortical iliac crest bone group (n = 8)...
July 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28337729/adjacent-level-disease-background-and-update-based-on-disc-replacement-data
#7
REVIEW
I David Kaye, Alan S Hilibrand
PURPOSE OF REVIEW: The precise etiology of adjacent segment disease following cervical spine surgery is controversial. Theories for development include inevitable changes secondary to the natural progression of the degenerative cascade and changes secondary to altered biomechanics of the fused cervical spine. Motion preserving techniques, such as cervical disc arthroplasties (CDA), have been introduced with the hopes of reducing the rates of adjacent segment pathology. Recently, 7-year data from the investigational device exemption (IDE) studies have been published...
June 2017: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/28178135/durability-of-cervical-disc-arthroplasties-and-its-influence-factors-a-systematic-review-and-a-network-meta-analysis
#8
REVIEW
Chao Chen, Xiaolin Zhang, Xinlong Ma
BACKGROUND: The durability of cervical disc arthroplasties (CDA) may vary significantly because of different designs and implanting techniques of the devices. Nevertheless, the comparative durability remains unknown. OBJECTIVES: We aimed to assess the durability of CDAs in at least 2-year follow-up. We analyzed the classifications and causes of secondary surgical procedures, as well as the structural designs of the devices that might influence the durability. METHODS: PubMed, Medline, Embase, and Cochrane Central Register of Controlled Trials were searched from the inception of each database to September 2015 using the following Keywords: "cervical disc replacement" OR "cervical disc arthroplasty" AND "randomized controlled trial (RCT)...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27627721/can-an-endplate-conformed-cervical-cage-provide-a-better-biomechanical-environment-than-a-typical-non-conformed-cage-a-finite-element-model-and-cadaver-study
#9
Fan Zhang, Hao-Cheng Xu, Bo Yin, Xin-Lei Xia, Xiao-Sheng Ma, Hong-Li Wang, Jun Yin, Ming-Hao Shao, Fei-Zhou Lyu, Jian-Yuan Jiang
OBJECTIVES: To evaluate the biomechanical characteristics of endplate-conformed cervical cages by finite element method (FEM) analysis and cadaver study. METHODS: Twelve specimens (C2 -C7 ) and a finite element model (C3 -C7 ) were subjected to biomechanical evaluations. In the cadaver study, specimens were randomly assigned to intact (I), endplate-conformed (C) and non-conformed (N) groups with C4-5 discs as the treated segments. The morphologies of the endplate-conformed cages were individualized according to CT images of group C and the cages fabricated with a 3-D printer...
August 2016: Orthopaedic Surgery
https://www.readbyqxmd.com/read/27243444/the-role-of-posterior-longitudinal-ligament-in-cervical-disc-replacement-an-ovine-cadaveric-biomechanical-analysis
#10
Cheng-Cheng Yu, Ding-Jun Hao, Yu-Li Ma, Da-Geng Huang, Hou-Kun Li, Hang Feng, Qian Hou
BACKGROUND Cervical disc replacement (CDR) has been widely used to restore and maintain mobility and function of the treated and adjacent motion segments. Posterior longitudinal ligament (PLL) resection has been shown to be efficient in anterior cervical decompression and fusion. However, less is known about the biomechanical effect of PLL removal versus preservation in cervical disc arthroplasty. MATERIAL AND METHODS Three motion segments of 24 ovine cervical spines (C2-C5) were evaluated in a robotic spine system with axial compressive loads of 50 N...
May 31, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/26321003/in-vitro-evaluation-of-translating-and-rotating-plates-using-a-robot-testing-system-under-follower-load
#11
Y Yan, K M Bell, R A Hartman, J Hu, W Wang, J D Kang, J Y Lee
BACKGROUND CONTEXT: Various modifications to standard "rigid" anterior cervical plate designs (constrained plate) have been developed that allow for some degree of axial translation and/or rotation of the plate (semi-constrained plate)-theoretically promoting proper load sharing with the graft and improved fusion rates. However, previous studies about rigid and dynamic plates have not examined the influence of simulated muscle loading. PURPOSE: The objective of this study was to compare rigid, translating, and rotating plates for single-level corpectomy procedures using a robot testing system with follower load...
January 2017: European Spine Journal
https://www.readbyqxmd.com/read/26230424/cervical-disc-arthroplasty-with-prestige-lp-disc-versus-anterior-cervical-discectomy-and-fusion-a-prospective-multicenter-investigational-device-exemption-study
#12
Matthew F Gornet, J Kenneth Burkus, Mark E Shaffrey, Perry J Argires, Hui Nian, Frank E Harrell
OBJECT This study compared the safety and efficacy of treatment with the PRESTIGE LP cervical disc versus a historical control anterior cervical discectomy and fusion (ACDF). METHODS Prospectively collected PRESTIGE LP data from 20 investigational sites were compared with data from 265 historical control ACDF patients in the initial PRESTIGE Cervical Disc IDE study. The 280 investigational patients with single-level cervical disc disease with radiculopathy and/or myelopathy underwent arthroplasty with a low-profile artificial disc...
July 31, 2015: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/26225278/prevalence-of-klippel-feil-syndrome-in-a-surgical-series-of-patients-with-cervical-spondylotic-myelopathy-analysis-of-the-prospective-multicenter-aospine-north-america-study
#13
Aria Nouri, Lindsay Tetreault, Juan J Zamorano, Chandan B Mohanty, Michael G Fehlings
Study Design Prospective study. Objective To evaluate the prevalence of Klippel-Feil syndrome (KFS) in a prospective data set of patients undergoing surgical treatment for cervical spondylotic myelopathy (CSM) and to evaluate if magnetic resonance imaging (MRI) features in patients with KFS are more pronounced than those of non-KFS patients with CSM. Methods A retrospective analysis of baseline MRI data from the AOSpine prospective and multicenter CSM-North American study was conducted. All the patients presented with at least one clinical sign of myelopathy and underwent decompression surgery...
August 2015: Global Spine Journal
https://www.readbyqxmd.com/read/26225276/biomechanical-determination-of-distal-level-for-fusions-across-the-cervicothoracic-junction
#14
Ivan Cheng, Eric B Sundberg, Alex Iezza, Derek P Lindsey, K Daniel Riew
Study Design In vitro testing. Objective To determine whether long cervical and cervicothoracic fusions increase the intradiscal pressure at the adjacent caudal disk and to determine which thoracic end vertebra causes the least increase in the adjacent-level intradiscal pressure. Methods A bending moment was applied to six cadaveric cervicothoracic spine specimens with intact rib cages. Intradiscal pressures were recorded from C7-T1 to T9-10 before and after simulated fusion by anterior cervical plating and posterior thoracic pedicle screw constructs...
August 2015: Global Spine Journal
https://www.readbyqxmd.com/read/25679235/endoscopic-endonasal-atlantoaxial-transarticular-screw-fixation-technique-an-anatomical-feasibility-and-biomechanical-study
#15
George A C Mendes, Curtis A Dickman, Nestor G Rodriguez-Martinez, Samuel Kalb, Neil R Crawford, Volker K H Sonntag, Mark C Preul, Andrew S Little
OBJECT The primary disadvantage of the posterior cervical approach for atlantoaxial stabilization after odontoidectomy is that it is conducted as a second-stage procedure. The goal of the current study is to assess the surgical feasibility and biomechanical performance of an endoscopic endonasal surgical technique for C1-2 fixation that may eliminate the need for posterior fixation after odontoidectomy. METHODS The first step of the study was to perform endoscopic endonasal anatomical dissections of the craniovertebral junction in 10 silicone-injected fixed cadaveric heads to identify relevant anatomical landmarks...
May 2015: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/25612849/construct-stability-of-an-instrumented-2-level-cervical-corpectomy-model-following-fatigue-testing-biomechanical-comparison-of-circumferential-antero-posterior-instrumentation-versus-a-novel-anterior-only-transpedicular-screw-plate-fixation-technique
#16
COMPARATIVE STUDY
Heiko Koller, Werner Schmoelz, Juliane Zenner, Alexander Auffarth, Herbert Resch, Wolfgang Hitzl, Davud Malekzadeh, Lukas Ernstbrunner, Martina Blocher, Michael Mayer
INTRODUCTION: A high rate of complications in multilevel cervical surgery with corpectomies and anterior-only screw-and-plate stabilization is reported. A 360°-instrumentation improves construct stiffness and fusion rates, but adds the morbidity of a second approach. A novel ATS-technique (technique that used anterior transpedicular screw placement) was recently described, yet no study to date has analyzed its performance after fatigue loading. Accordingly, the authors performed an analysis of construct stiffness after fatigue testing of a cervical 2-level corpectomy model reconstructed using a novel anterior transpedicular screw-and-plate technique (ATS-group) in comparison to standard antero-posterior instrumentation (360°-group)...
December 2015: European Spine Journal
https://www.readbyqxmd.com/read/25584947/a-zero-profile-anchored-spacer-in-multilevel-cervical-anterior-interbody-fusion-biomechanical-comparison-to-established-fixation-techniques
#17
COMPARATIVE STUDY
Matti Scholz, Philipp Schleicher, Simone Pabst, Frank Kandziora
STUDY DESIGN: In vitro biomechanical analysis of different multilevel cervical fixation techniques. OBJECTIVE: To compare the multilevel stability of a cervical anchored spacer (AS) with established fixation techniques. SUMMARY OF BACKGROUND DATA: To avoid plate-related complications, for example, dysphagia zero-profile AS has been developed. The use of these new zero-profile implants for treatment of cervical degenerative disc disease is widely accepted after encouraging biomechanical results for single-level instrumentation...
April 1, 2015: Spine
https://www.readbyqxmd.com/read/25365710/fusion-nonfusion-hybrid-construct-versus-anterior-cervical-hybrid-decompression-and-fusion-a-comparative-study-for-3-level-cervical-degenerative-disc-diseases
#18
COMPARATIVE STUDY
Fan Ding, Zhiwei Jia, Yaohong Wu, Chao Li, Qing He, Dike Ruan
STUDY DESIGN: A retrospective analysis. OBJECTIVE: This study aimed to compare the safety and efficacy between the fusion-nonfusion hybrid construct (HC: anterior cervical corpectomy and fusion plus artificial disc replacement, ACCF plus cADR) and anterior cervical hybrid decompression and fusion (ACHDF: anterior cervical corpectomy and fusion plus discectomy and fusion, ACCF plus ACDF) for 3-level cervical degenerative disc diseases (cDDD). SUMMARY OF BACKGROUND DATA: The optimal anterior technique for 3-level cDDD remains uncertain...
November 1, 2014: Spine
https://www.readbyqxmd.com/read/25271506/malaligned-dynamic-anterior-cervical-plate-a-biomechanical-analysis-of-effectiveness
#19
Brandon D Lawrence, Alpesh A Patel, Andrew Guss, W Ryan Spiker, Darrel S Brodke
STUDY DESIGN: Biomechanical evaluation. OBJECTIVE: To evaluate the kinematic and load-sharing differences of dynamic anterior cervical plates when placed in-line at 0° and off-axis at 20°. SUMMARY OF BACKGROUND DATA: The use of dynamic anterior cervical plating systems has recently gained popularity due to the theoretical benefit of improved load sharing with graft subsidence. Occasionally, due to anatomical restraints, the anterior cervical plate may be placed off-axis in the coronal plane...
December 1, 2014: Spine
https://www.readbyqxmd.com/read/25036218/clinical-and-radiographic-analysis-of-an-artificial-cervical-disc-7-year-follow-up-from-the-prestige-prospective-randomized-controlled-clinical-trial-clinical-article
#20
RANDOMIZED CONTROLLED TRIAL
J Kenneth Burkus, Vincent C Traynelis, Regis W Haid, Praveen V Mummaneni
OBJECT: The authors assess the long-term safety and efficacy of cervical disc replacement with the Prestige Cervical Disc in a prospective, randomized, multicenter trial at 7 years of follow-up. METHODS: At 31 investigational sites, 541 patients with single-level cervical disc disease with radiculopathy were randomized to 1 of 2 treatment groups: 276 investigational group patients underwent anterior cervical discectomy and arthroplasty with the Prestige disc, and 265 control group patients underwent anterior cervical discectomy and fusion...
October 2014: Journal of Neurosurgery. Spine
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