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https://www.readbyqxmd.com/read/29973085/abdominal-computed-tomography-ct-scan-in-the-evaluation-of-refractory-puerperal-fever-impact-on-management
#1
Michal Fishel Bartal, Baha M Sibai, Tali Ben-Mayor Bashi, Ayelet Dangot, Irit Schushan Eisen, Mordechai Dulitzki, Yael Inbar, Shali Mazaki-Tovi, Israel Hendler
INTRODUCTION: Computed tomography (CT) imaging should be employed judiciously, given its cost, use of intravenous contrast and ionizing radiation. The aim of this study was to determine the clinical benefit of a CT scan in the evaluation of refractory puerperal fever and to identify the appropriate candidates for its use. METHODS: This was a retrospective cohort study conducted in a single tertiary care center between 01/2007-04/2017. Indications for CT scan were refractory postpartum fever of ≥ 3 days and/or ultrasound findings suggesting complex abdominal fluid collection...
July 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29954356/incidence-of-postpartum-infection-outcomes-and-associated-risk-factors-at-mbarara-regional-referral-hospital-in-uganda
#2
Joseph Ngonzi, Lisa M Bebell, Yarine Fajardo, Adeline A Boatin, Mark J Siedner, Ingrid V Bassett, Yves Jacquemyn, Jean-Pierre Van Geertruyden, Jerome Kabakyenga, Blair J Wylie, David R Bangsberg, Laura E Riley
BACKGROUND: There is a paucity of recent prospective data on the incidence of postpartum infections and associated risk factors in sub-Saharan Africa. Retrospective studies estimate that puerperal sepsis causes approximately 10% of maternal deaths in Africa. METHODS: We enrolled 4231 women presenting to a Ugandan regional referral hospital for delivery or postpartum care into a prospective cohort and measured vital signs postpartum. Women developing fever (> 38...
June 28, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29936859/-the-savior-of-mothers-and-newborns-whom-we-shall-always-be-proud-of-ign%C3%A3-c-semmelweis-1818-1865-one-who-defeated-the-disease-yet-could-not-convince-the-people-doctor-of-medical-sciences-and-surgery-master-of-obstetrics-professor-of-theoretical-and-practical
#3
László Rosivall
Semmelweis finally achieved results from his persistent research work. Those being the scientific analysis of clinical statistical data and his animal experiments, which recognized the dreadful disease of puerperal fever and its prevention. "He not only discovered the real cause of puerperal fever but he also created antiseptic prophylaxis, which he introduced in obstetrics and laid the foundations of modern surgery (asepsis). The theory and practice of asepsis stemmed from the discovery of the etiology of puerperal fever and therefore originating from the genius idea of Semmelweis...
July 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29936856/-semmelweis-a-contemplating-human-scientific-historical-lessons
#4
István Gazda
In this article we examine why Semmelweis's seemingly simple, logical and practical discovery was categorically dismissed by the majority of his contemporaries, and why even many years after his death it was accepted with such reservation. We invoke wherever possible Semmelweis's own words citing from the series of articles appearing in the 'Orvosi Hetilap' [Hungarian Medical Weekly Journal] published in 1858 in Hungary, and also from the German language summary of the Journal published in 1860. We came to the conclusion that although Semmelweis did everything in his power to show the causal relationship between the development of puerperal fever (childbed fever) and some infectious substance on the hands of examining doctors and medical students, this was not convincing enough...
July 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29936855/-ign%C3%A3-c-semmelweis-and-the-hungarian-medical-weekly-journal
#5
László Kiss
Ignác Semmelweis did not publish his discovery in Vienna - i.e., that the puerperal fever may be prevented by careful washing of the hand in chlorine solution (asepsis) - for ten years. The Medical Weekly started its publications edited by Lajos Markusovszky in Pest in 1857. Semmelweis as a professor of theoretical and practical obstetrics at the University of Pest published a study about puerperal fever in the first volume, and Hungarian physicians became familiar with Semmelweis' opinion from this medical journal...
July 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29936853/-laudation-to-the-midwives-midwives-and-the-puerperal-fever
#6
László Iffy
Originally published in the Hungarian Postgraduate Journal of Gynecology and Obstetrics (2016; 18: 209-2013). Reprint with the contribution and permission of the Professional Publishing Hungary Kft., Budapest. Orv Hetil. 2018; 159(26): 1079-1083.
July 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29594006/postpartum-septic-pelvic-thrombophlebitis-after-caesarean-delivery-a-case-report
#7
Margarida da Silva Cunha, Ana Beatriz Godinho, Rosário Botelho, José Pinto de Almeida
Septic pelvic thrombophlebitis is a rare puerperal complication. It is an important differential diagnosis of postpartum fever and abdominal pain and although the condition is well known its diagnosis can be challenging. We report a case of a 41-year-old woman with fever and right abdominal pain three days after an uncomplicated caesarean delivery. Clinical, laboratory and imaging exams were unremarkable and the patient was treated for endometritis. In the absence of improvement despite an antibiotic adjustment, a clinical diagnosis of septic pelvic thrombophlebitis was made, and the patient presented a good response to anticoagulation in conjunction with broad-spectrum antibiotic therapy...
January 2018: Case Reports in Women's Health
https://www.readbyqxmd.com/read/29381182/klassisk-barns%C3%A3-ngsfeber-existerar-fortfarande-9-fall-bland-anm%C3%A3-lningar-till-l%C3%A3-f-under-2010%C3%A2-2014
#8
Akke Alberts, Agneta Blanck Olerup, Pelle Gustafson
Puerpural fever still exist. A rare condition that must be kept in mind All 33 claims to the Swedish National Patient Insurance (LÖF) in 2010-2014 related to obstetric infections, of which 14 were due to endometritis, were examined. Nine women suffered from fulminant infections consistent with classical puerperal fever (childbed fever), 2 of which were life-threatening. They occurred unexpectedly, mainly after uncomplicated deliveries, and were usually caused by Group A streptococci. Five women suffered from endometritis with a mild or moderate clinical course...
January 26, 2018: Läkartidningen
https://www.readbyqxmd.com/read/28885399/clinical-risk-factors-associated-with-peripartum-maternal-bacteremia
#9
Sarah Rae Easter, Rose L Molina, Kartik K Venkatesh, Anjali Kaimal, Ruth Tuomala, Laura E Riley
OBJECTIVE: To evaluate risk factors associated with maternal bacteremia in febrile peripartum women. METHODS: We performed a case-control study of women with fevers occurring between 7 days before and up to 42 days after delivery of viable neonates at two academic hospitals. Women with positive blood cultures were matched with the next two febrile women meeting inclusion criteria with negative blood cultures in the microbiology data without other matching parameters...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28847070/-study-on-the-19-th-century-puerperal-fever-epidemic-semmelweis-an-often-neglected-pioneer-epidemiologist
#10
Q Feng, J L Tang
Puerperal fever was a major cause of maternal death in Europe in the 19(th) century. Many efforts were made to investigate the cause of the epidemic but failed. In 1846, Semmelweis, a young obstetrician in Vienna General Hospital, started his historical investigation. His breakthrough was largely due to his doctor friend's accidental injury during autopsy and his consequential death. Semmelweis found the pathological findings in his friend's post mortem examination were very similar to puerperal fever. He postulated his friend's death might be caused by "cadaverous particles" from cadavers and further inferred that puerperal fever might also be caused by the cadaverous particles that doctors brought to the delivering women after autopsy classes...
August 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28406949/antimicrobial-resistant-infections-among-postpartum-women-at-a-ugandan-referral-hospital
#11
Lisa M Bebell, Joseph Ngonzi, Joel Bazira, Yarine Fajardo, Adeline A Boatin, Mark J Siedner, Ingrid V Bassett, Dan Nyehangane, Deborah Nanjebe, Yves Jacquemyn, Jean-Pierre van Geertruyden, Juliet Mwanga-Amumpaire, David R Bangsberg, Laura E Riley, Yap Boum
INTRODUCTION: Puerperal sepsis causes 10% of maternal deaths in Africa, but prospective studies on incidence, microbiology and antimicrobial resistance are lacking. METHODS: We performed a prospective cohort study of 4,231 Ugandan women presenting to a regional referral hospital for delivery or postpartum care, measured vital signs after delivery, performed structured physical exam, symptom questionnaire, and microbiologic evaluation of febrile and hypothermic women...
2017: PloS One
https://www.readbyqxmd.com/read/28272244/management-of-patients-with-placenta-accreta-in-association-with-fever-following-vaginal-delivery
#12
Liuying Zhong, Dunjin Chen, Mei Zhong, Yutian He, Chunhong Su
This study aims to analyze the clinical characteristics and to manage patients with retained placenta left in situ accompanied by fever following vaginal delivery.Twenty-one patients with retained placenta in association with fever following vaginal delivery were enrolled and managed at the maternity department of our university hospital between 2012 and 2014.All patients had risk factors for development of placenta accreta: previous cesarean sections (4/21), previous curettage (15/21), or uterine malformations (7/21)...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28130432/azithromycin-in-labor-lowers-clinical-infections-in-mothers-and-newborns-a-double-blind-trial
#13
RANDOMIZED CONTROLLED TRIAL
Claire Oluwalana, Bully Camara, Christian Bottomley, Sean Goodier, Abdoulie Bojang, Beate Kampmann, Samba Ceesay, Umberto D'Alessandro, Anna Roca
BACKGROUND AND OBJECTIVES: We have recently completed a proof-of-concept trial showing that bacterial colonization decreased in women and newborns after the administration of azithromycin during labor. Here, we aim to assess the effect of the intervention on maternal and neonatal clinical infections. METHODS: This was a double-blind, placebo-controlled randomized trial. Gambian women in labor were given either an oral dose of azithromycin (2 g) or placebo. Follow-up was conducted for 8 weeks after delivery...
February 2017: Pediatrics
https://www.readbyqxmd.com/read/27976471/coxiella-burnetii-serological-reactions-and-bacterial-shedding-in-primiparous-dairy-cows-in-an-endemically-infected-herd-impact-on-milk-yield-and-fertility
#14
M Freick, H Enbergs, J Walraph, R Diller, J Weber, A Konrath
Coxiella burnetii (C. burnetii) is the causative agent of Q fever both in humans and animals. The objectives of this study were to investigate seropositivity and bacterial shedding in heifers and primiparous cows in an endemically infected herd and to assess the effects on post-partum diseases, fertility and milk production. At the age of 9 months, 96 Holstein heifers were included. Sampling was performed reproduction-orientated: at the beginning of the study, at detection of first pregnancy, 3 weeks before expected calving date (blood serum), at parturition and after 21, 42, 100 and 150 days in milk (DIM) (blood serum, vaginal swabs and milk)...
February 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27832812/a-longitudinal-cohort-study-of-acute-puerperal-metritis-cases-in-swedish-dairy-cows
#15
Anna Ordell, Helle Ericsson Unnerstad, Ann Nyman, Hans Gustafsson, Renée Båge
BACKGROUND: Acute puerperal metritis affects cows during the early postpartum period and causes fever, fetid vaginal discharge and general depression. The disease is severe and treatment with antimicrobials is often required. This study followed 79 Swedish dairy cows with acute puerperal metritis with registered treatment and outcome in terms of recovery. Bacteria isolated from the uterus and their susceptibility to penicillin were studied. Clinical cases were assigned by participating practitioners who examined the cows, performed uterine swab sampling, decided treatment and provided information about cow health and calving conditions...
November 10, 2016: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/27744364/disease-outbreaks-as-vehicles-for-exploring-engaged-citizen-themes-through-a-course-on-the-history-of-infectious-diseases
#16
David S Senchina
Infectious diseases are potential catalysts for exploring 'engaged citizen' or socioscientific themes given their interwoven economic, political, scientific and social dimensions. This article describes how an undergraduate course on the history of infectious diseases was modified to explore the impact of two 'engaged citizen' themes (poverty and technology), and to consider the ramifications of those themes on past, present and future infectious disease outbreaks. Four outbreaks were used as the foundation for the course: plague (1350s), puerperal fever (1840s), cholera (1850s) and syphilis (1930s)...
January 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/27581586/dilatation-or-no-dilatation-of-the-cervix-during-cesarean-section-dondi-trial-a-randomized-controlled-trial
#17
RANDOMIZED CONTROLLED TRIAL
Jade Kirscht, Christel Weiss, Jana Nickol, Sebastian Berlit, Benjamin Tuschy, Benjamin Hoch, Amelie-Verena Trebin, Thomas Große-Steffen, Marc Sütterlin, Sven Kehl
PURPOSE: To assess the effects of mechanical dilatation of the cervix during cesarean section on postoperative morbidity. METHODS: A total of 447 women with elective cesarean section were included in the Dondi trial (Dilatation or no dilatation of the cervix during cesarean section). The primary outcome measure of this randomized controlled trial was postpartum hemorrhage (PPH) within 6 weeks. Infectious morbidity (puerperal fever, endometritis, wound infection, and urinary tract infection), blood loss (need for blood transfusion or change in hemoglobin levels), and operating time were also evaluated...
January 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27512432/post-partum-infections-a-review-for-the-non-obgyn
#18
E Dalton, E Castillo
The epidemiology of infections in the puerperium (post partum period) is not well understood and remains underestimated because surveillance systems are often limited to the acute care setting. The most common source of persistent fever after delivery is genital tract infection for which diagnosis remains mostly clinical and antibiotic treatment empiric. This review will emphasize surgical site infections (SSIs) and endometritis. Septic thrombo-phlebitis, mastitis, urinary tract infections and rare infections will be covered in less detail...
September 2014: Obstetric Medicine
https://www.readbyqxmd.com/read/27413718/scrub-typhus-masquerading-as-hellp-syndrome-and-puerperal-sepsis-in-an-asymptomatic-malaria-patient
#19
Habib Md Reazaul Karim, Prithwis Bhattacharyya, Sonai Datta Kakati, Tridip Jyoti Borah, Md Yunus
Scrub typhus and malaria can involve multiple organ systems and are notoriously known for varied presentations. However, clinical malaria or scrub typhus is unusual without fever. On the other hand, altered sensorium with or without fever, dehydration, hemorrhage and hemolysis may lead to low blood pressure. Presence of toxic granules and elevated band forms in such patients can even mimic sepsis. When such a patient is in the peripartum period, it creates a strong clinical dilemma for the physician especially in unbooked obstetric cases...
2016: Qatar Medical Journal
https://www.readbyqxmd.com/read/27181742/-no-good-deed-goes-unpunished-ignaz-semmelweis-and-the-story-of-puerperal-fever
#20
Joshua Manor, Nava Blum, Yoav Lurie
Ignác Fülöp Semmelweis was born almost 200 years ago, in 1818, to a well-to-do middle class Hungarian family. He started law school in 1837, switched to medicine a year later, and graduated in 1844.
August 2016: Infection Control and Hospital Epidemiology
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