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Botulinum cosmetic

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https://www.readbyqxmd.com/read/30091253/italian-consensus-report-on-the-aesthetic-use-of-onabotulinum-toxin-a
#1
Dario Bertossi, Maurizio Cavallini, Pierfrancesco Cirillo, Salvatore Piero Fundarò, Sandro Quartucci, Chantal Sciuto, Davide Tonini, Gloria Trocchi, Massimo Signorini
BACKGROUND: The aesthetic treatment of facial and neck wrinkles with botulinum toxin is constantly increasing, thus making it necessary to collect procedures guidelines for the use of botulinum toxin in the treatment of wrinkles and/or cosmetic defects. METHODS: A group of nine Italian doctors, plastic and maxillo-facial surgeons, dermatologists and aesthetic physicians, experts in face and neck aesthetic treatments with onabotulinum toxin A, discussed on procedures used in their clinical practice...
August 9, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/30072597/botulinum-toxin-induced-atrophy-an-uncharted-territory
#2
REVIEW
Mehri Salari, Soumya Sharma, Mandar S Jog
Botulinum neurotoxins (BoNTs) produce local chemo-denervation by cleaving soluble N-ethylmaleimide-sensitive factor activating protein receptor (SNARE) proteins. Botulinum neurotoxins are therapeutically indicated in several neurological disorders and have been in use for three decades. The long-term efficacy, safety, and side effects of BoNTs have been well documented in the literature. However, the development of muscle atrophy following chronic exposure to BoNTs has not received sufficient attention. Muscle atrophy is not only cosmetically distressing, but also has an impact on future injections...
August 2, 2018: Toxins
https://www.readbyqxmd.com/read/30019241/a-randomized-placebo-controlled-double-blind-prospective-clinical-trial-of-botulinum-toxin-type-a-in-prevention-of-hypertrophic-scar-development-in-median-sternotomy-wound
#3
Yue-Hua Li, Jiaomei Yang, Jia-Qi Liu, Song-Tao Xie, Yi-Jie Zhang, Wei Zhang, Ju-Lei Zhang, Zhao Zheng, Da-Hai Hu
BACKGROUND: Linear hypertrophic scar is a common surgical problem that can be difficult to manage, especially for the median sternotomy scar. Botulinum toxin type A (BTA) is widely used in cosmetic surgery and has been shown to improve scar quality recently. The aim of this study was to evaluate the efficacy of BTA injected in the early postoperative of median sternotomy on preventing scar formation. METHODS: In this prospective randomized controlled trial, 19 consecutive patients who underwent median sternotomy were enrolled...
July 17, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29985176/controversies-in-periocular-reconstruction-for-facial-nerve-palsy
#4
Richard C Allen
PURPOSE OF REVIEW: Periocular rehabilitation of the patient with a facial nerve palsy has evolved over time. Although protection of the ocular surface is paramount, application of disfiguring tarsorrhaphies should be utilized only in special situations. The purpose of this review is to discuss current surgical and medical strategies in treatment of the periocular area in patients with facial nerve palsy to give maximal functional and cosmetic results. RECENT FINDINGS: Upper lid lagophthalmos is preferentially treated with upper eyelid weights...
July 4, 2018: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29982282/simulation-an-effective-method-of-teaching-cosmetic-botulinum-toxin-injection-technique
#5
Mario V Mitkov, Colleen S Thomas, Jordan J Cochuyt, Antonio J Forte, Galen Perdikis
Background: Learning to inject botulinum toxin for cosmetic purposes is difficult for beginners given the nature of the procedure and patient population. Simulation training is an effective modality for medical professionals to acquire skills in an environment that provides low stress and ample opportunity for questions and correction of mistakes. Objective: Compare posttraining comfort, knowledge, and practical botulinum toxin injection scores between trainees who underwent simulation versus video training only...
July 3, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29948095/body-image-personality-traits-and-quality-of-life-in-botulinum-toxin-a-and-dermal-filler-patients
#6
Dagmar Scharschmidt, Ursula Mirastschijski, Simone Preiss, Elmar Brähler, Tanja Fischer, A Borkenhagen
BACKGROUND: The demand for minimally invasive cosmetic procedures has continued to rise, especially in Germany, yet few studies have examined this patient population. The literature in Germany has repeatedly voiced the speculation that users of minimally invasive, skin-rejuvenating procedures displayed a higher tendency toward dysmorphic behavior patterns or, respectively, other abnormal personality traits. OBJECTIVES: The aim of this study was to investigate body image, personality traits, quality of life, and socioeconomic parameters in users of botulinum toxin and/or facial fillers...
August 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29910630/botulinum-neurotoxin-formulations-overcoming-the-confusion
#7
REVIEW
Souphiyeh Samizadeh, Koenraad De Boulle
Botulinum toxin A is produced by anaerobic spore-forming bacteria and is used for various therapeutic and cosmetic purposes. Botulinum toxin A injections are the most popular nonsurgical procedure worldwide. Despite an increased demand for botulinum toxin A injections, the clinical pharmacology and differences in formulation of commonly available products are poorly understood. The various products available in the market are unique and vary in terms of units, chemical properties, biological activities, and weight, and are therefore not interchangeable...
2018: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/29735936/experimental-intrastriatal-applications-of-botulinum-neurotoxin-a-a-review
#8
REVIEW
Alexander Hawlitschka, Andreas Wree
Parkinson’s disease (PD) is one of the most frequent neurodegenerative disorders. Its main pathophysiological characteristic is the loss of dopaminergic neurons in the substantia nigra pars compacta followed by a lack of striatal dopaminergic input and a consequent disinhibition of tonically active cholinergic interneurons. The resulting striatal hypercholinism causes major motor symptoms in PD. Anticholinergic pharmacotherapies have antiparkinsonian effects on motor symptoms, but, due to systemic actions, also numerous severe side effects occur on a regular basis...
May 7, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29697624/accessory-nerves-of-the-forehead-a-newly-discovered-frontotemporal-neurovascular-bundle-and-its-implications-in-the-treatment-of-migraine-headache-migraine-surgery-and-cosmetic-temple-filler-injection
#9
Bardia Amirlak, Michael H Chung, Ronnie A Pezeshk, Kyle Sanniec
BACKGROUND: Surgical decompression of peripheral cranial and spinal nerves at several anatomically studied trigger sites has demonstrated significant efficacy in bringing permanent relief to migraine sufferers. In their experience performing frontal nerve decompression on migraine patients, the authors noticed a previously undescribed accessory nerve and vessel in the frontotemporal area, and report its implication in migraine surgery and cosmetic filler injection. METHODS: A retrospective review of 113 patients who underwent frontal migraine decompression surgery at the University of Texas Southwestern Medical Center from July of 2011 to May of 2016 was performed...
May 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29667799/shrink-that-frown-botulinum-toxin-therapy-is-lifting-the-face-of-psychiatry
#10
M Axel Wollmer, Insa Neumann, Michelle Magid, Tillmann H Kruger
Treating glabellar frown lines with injections of botulinum toxin is the most frequently applied procedure in aesthetic medicine. In addition to its cosmetic effect, botulinum toxin may also positively modulate mood and affect, which may contribute to its popularity. A series of clinical studies has shown that this modulation can be used in the treatment of major depression. After a single glabellar treatment with botulinum toxin, patients suffering from unipolar depression experienced a quick, strong and sustained improvement in the symptoms of depression...
August 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29515393/incidental-treatment-of-a-subclinical-chronic-tension-type-headache-by-cosmetic-use-of-botulinum-toxin-a-a-case-report
#11
Iselin Saltvig, Steen Henrik Matzen
Background: Headache is a common disorder of the nervous system; chronic headache in particular may affect quality of life negatively. The pathophysiology is multifactorial and not completely elucidated. Studies have demonstrated the beneficial effects of botulinum toxin A on chronic migraine headaches, but failed to show the same effect on chronic tension-type headaches. Methods: We present the case of a 32-year-old woman who after receiving cosmetic injections with botulinum toxin A for fine lines of the forehead experienced relief of subclinical tension-type headaches...
September 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/29428994/occipitalis-muscle-using-for-repetitive-facial-nerve-stimulation-in-myasthenia-gravis
#12
Ahmet Yildirim, Turgut Adatepe, Aysegul Gunduz, Orhan Yagiz, Nurten Uzun
Repetitive nerve stimulation (RNS) is a highly sensitive electrophysiological test used for diagnosing myasthenia gravis (MG). Here, we evaluated electrodiagnostic value of RNS using facial nerve and occipitalis muscle. Patients with generalized MG were included. Clinical findings were assessed. RNS test was performed on occipitalis, nasalis, trapezius, abductor policis brevis (APB) and abductor digiti minimi (ADM) muscles. Twenty-five (78%) patients had relevant decrement during RNS test of at least one muscle...
February 10, 2018: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29384393/intralesional-botulinum-toxin-a-injection-for-the-treatment-of-multiple-eccrine-hidrocystomas
#13
Mehdi Gheisari, Behnaz Hamedani, RezaM Robati, Nikoo Mozafari
BACKGROUND: Multiple eccrine hidrocystomas (MEH) are benign cystic lesions of the sweat gland ducts. They are characterized by translucent, skin-colored or bluish dome-shaped papules on the face, causing cosmetic concern. Recently, botulinum toxin-A, because of its antiperspirant properties, has been used to treat facial MEH. However, there are only some case reports in the literature. OBJECTIVE: Here, we conducted a prospective study to assess the efficacy and safety of intralesional injection of botulinum toxin-A (Dysport) for the treatment of MEH...
January 31, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29343468/onabotulinum-toxin-a-injections-for-sleep-bruxism-a-double-blind-placebo-controlled-study
#14
William G Ondo, Jerald H Simmons, Muhammad H Shahid, Vera Hashem, Christine Hunter, Joseph Jankovic
OBJECTIVES: To test the safety and efficacy of onabotulinum toxin-A (BoNT-A) injections into the masseter and temporalis muscles in patients with symptomatic sleep bruxism. METHODS: Participants 18 to 85 years old with clinically diagnosed sleep bruxism confirmed by polysomnography were enrolled in this randomized, placebo-controlled, 1:1, parallel-design trial with open-label extension. Participants were injected with BoNT-A 200 units (60 into each masseter and 40 into each temporalis) or placebo and were evaluated at 4 to 8 weeks after the initial treatment visit...
February 13, 2018: Neurology
https://www.readbyqxmd.com/read/29325384/-diagnosis-and-treatment-of-strabismus-caused-by-nasal-endoscopic-surgery
#15
L K Ai, X Wu, J N Wang, J Li, Y Wu, J Zhou, W X Song, R L Guo
Objective: Strabismus with diplopia is the main orbital complication of functional endoscopic sinus surgery (FESS). This study was to analyze clinical findings, treatment and outcomes of such cases. Methods: Retrospective case series. Twenty-three cases were divided into 3 groups based on the disease severity: group A, partial transection of the medial rectus muscle, group B, complete transection of the medical rectus, group C, transection of the medial rectus combined with the other orbital injuries. Complete ophthalmology examinations, including eye alignment, eye motility, force duction test, force generation test, general eye exam, and medical imaging (orbital CT or MRI), were performed for each case...
December 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29258169/botulinum-toxin-in-the-field-of-dermatology-novel-indications
#16
REVIEW
Yoon Seob Kim, Eun Sun Hong, Hei Sung Kim
Since its approval by the US Food and Drug Administration in 2002 for glabellar wrinkles, botulinum toxin (BTX) has been widely used to correct facial wrinkles. As a result, many consider BTX synonymous with cosmetic dermatology. Recent studies indicate that BTX elicits biological effects on various skin cell types via the modulation of neurotransmitter release, and it seems that BTX has a wider zone of dermatologic influence than originally understood. Clinicians and researchers are now beginning to explore the potential of BTX beyond the amelioration of facial lines and encouraging results are seen with BTX in a variety of skin conditions...
December 16, 2017: Toxins
https://www.readbyqxmd.com/read/29108543/the-use-of-neurotoxins-in-the-male-face
#17
REVIEW
Isabela T Jones, Sabrina G Fabi
Injection of neurotoxin is the most commonly performed cosmetic procedure in the United States, and the total number of male patients seeking botulinum has steadily increased over the years. Because of their unique aesthetic goals, expectations, and anatomy, men require differing botulinum toxin doses and techniques. This article provides an evidence-based approach to botulinum toxin in men. Each area of the face is discussed separately, focusing on gender differences in anatomy, treatment goals, and injection method...
January 2018: Dermatologic Clinics
https://www.readbyqxmd.com/read/29096852/therapeutic-plasma-exchange-in-a-rare-case-myasthenic-crisis-after-botox-injection
#18
Azita Chegini
BACKGROUND AND AIMS: Botulinum toxin (Botox) injections are used as a cosmetic treatment to decrease wrinkles in face and chin. Being a neurotoxic agent it minimizes muscle activity, while side effects are usually rare. This article subsequently presents one case of these rare effects. CASE: A 30-year-old woman presenting with ptosis, diplopia, dysarthria, dysphagia and muscle weakness was admitted to our hospital. She had no history of disease. For cosmetic reasons, she had three Botox injections during the preceding months...
November 2017: Atherosclerosis. Supplements
https://www.readbyqxmd.com/read/29084148/neurophysiological-measures-of-efficacy-and-safety-for-botulinum-toxin-injection-in-facial-and-bulbar-muscles-special-considerations
#19
REVIEW
Mohammad Alimohammadi, Anna Rostedt Punga
Botulinum toxin (BoNT) injections into facial and bulbar muscles are widely and increasingly used as medical treatments for cervical and facial dystonia, facial hemispasm, correction of facial palsy, hyperhidrosis, as well as cosmetic treatment of glabellar lines associated with grief and anger. Although BoNT treatment is generally considered safe, the diffusion of the toxin to surrounding muscles may result in complications, including difficulties swallowing, in a dose-dependent manner. The sensitivity of clinical examination for detecting adverse events after BoNT treatment is limited...
October 30, 2017: Toxins
https://www.readbyqxmd.com/read/29064991/efficacy-of-incobotulinumtoxina-for-the-treatment-of-glabellar-frown-lines-in-male-subjects-post-hoc-analyses-from-randomized-double-blind-pivotal-studies
#20
RANDOMIZED CONTROLLED TRIAL
Derek H Jones, Martina Kerscher, Thorin Geister, Michael A Hast, Petra Weissenberger
BACKGROUND: Males are increasingly seeking minimally invasive cosmetic procedures such as botulinum toxin injection. However, few studies have specifically examined the efficacy of such procedures among men. OBJECTIVE: To assess the efficacy of incobotulinumtoxinA for treating glabellar frown lines (GFLs) in men. METHODS: Three incobotulinumtoxinA studies were included in post hoc analyses of responder rates: 2 pivotal Phase 3 US registration studies for GFLs (n = 55 males in a pooled analysis) and a European pivotal Phase 3 study for upper facial lines (UFLs; n = 21 males)...
November 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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