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https://www.readbyqxmd.com/read/28801444/radical-cystectomy-bladder-removal-against-intravesical-bcg-immunotherapy-for-high-risk-non-muscle-invasive-bladder-cancer-bravo-a-protocol-for-a-randomised-controlled-feasibility-study
#1
Jamie B Oughton, Heather Poad, Maureen Twiddy, Michelle Collinson, Victoria Hiley, Kathryn Gordon, Mark Johnson, Sunjay Jain, Aidan P Noon, Rohit Chahal, Matt Simms, Mohantha Dooldeniya, Phillip Koenig, Louise Goodwin, Julia M Brown, James W F Catto
INTRODUCTION: High-risk non-muscle invasive bladder cancer (HRNMIBC) is a heterogeneous disease that can be difficult to predict. While around 25% of cancers progress to invasion and metastases, the remaining majority of tumours remain within the bladder. It is uncertain whether patients with HRNMIBC are better treated with intravesical maintenance BCG (mBCG) immunotherapy or primary radical cystectomy (RC). A definitive randomised controlled trial (RCT) is needed to compare these two different treatments but may be difficult to recruit to and has not been attempted to date...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28796728/patient-hospital-and-geographic-disparities-in-laparoscopic-surgery-use-among-surveillance-epidemiology-and-end-results-medicare-patients-with-colon-cancer
#2
Kendra L Ratnapradipa, Min Lian, Donna B Jeffe, Nicholas O Davidson, Jan M Eberth, Sandi L Pruitt, Mario Schootman
BACKGROUND: Surgical resection is the primary treatment for colon cancer, but use of laparoscopic approaches varies widely despite demonstrated short- and long-term benefits. OBJECTIVE: The purpose of this study was to identify characteristics associated with laparoscopic colon cancer resection and to quantify variation based on patient, hospital, and geographic characteristics. DESIGN: Bayesian cross-classified, multilevel logistic models calculated adjusted ORs and CIs for patient, surgeon, hospital, and geographic characteristics and unexplained variability (predicted vs...
September 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28795343/systematic-review-health-promotion-and-disease-prevention-among-hmong-adults-in-the-usa
#3
Maichou Lor
Although disparities in the burden of disease and illness experienced across major racial and ethnic groups in the USA is well known, little is known about subgroups, including the Hmong population. This review sought to determine the current state of health disparities related to health promotion and disease prevention among Hmong adults from 1975 to 2015. Seventy-one descriptive (qualitative, mixed methods, and quantitative) studies were reviewed. Most focused on two areas: (1) health status (mainly breast and cervical cancers) and (2) health-related behaviors...
August 9, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28791616/addressing-cultural-determinants-of-health-for-latino-and-hmong-patients-with-limited-english-proficiency-practical-strategies-to-reduce-health-disparities
#4
Linda Park, R J Schwei, P Xiong, E A Jacobs
We explored how addressing culture may improve patient-provider relationships and reduce health disparities for racial and ethnic individuals with limited English proficiency (LEP). We analyzed qualitative data collected to explore health disparities in preventive cancer screenings for Hmong and Spanish-speaking LEP patients in a large Midwest healthcare system. We interviewed 20 participants (10 from each group) and the audiotaped interviews were transcribed verbatim, then back translated focusing on meaning...
August 8, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28789670/patient-centered-boundary-mechanisms-to-foster-intercultural-partnerships-in-health-care-a-case-study-in-guatemala
#5
Martin Hitziger, Mónica Berger Gonzalez, Eduardo Gharzouzi, Daniela Ochaíta Santizo, Regina Solis Miranda, Andrea Isabel Aguilar Ferro, Ana Vides-Porras, Michael Heinrich, Peter Edwards, Pius Krütli
BACKGROUND: Up to one half of the population in Africa, Asia and Latin America has little access to high-quality biomedical services and relies on traditional health systems. Medical pluralism is thus in many developing countries the rule rather than the exception, which is why the World Health Organization is calling for intercultural partnerships to improve health care in these regions. They are, however, challenging due to disparate knowledge systems and lack of trust that hamper understanding and collaboration...
August 8, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28783852/regional-and-socioeconomic-differences-in-the-coverage-of-the-papanicolau-test-in-brazil-data-from-the-brazilian-health-survey-2013
#6
Isabelle Ribeiro Barbosa
Purpose To evaluate the coverage of the Papanicolaou test in Brazil and the associated factors. Methods Cross-sectional study based on data from the Brazilian Health Survey 2013 comprising the proportion of 25- to 64-year-old women who had undergone a Papanicolaou test within the previous 3 years, categorized by sociodemographic variables and access to healthcare services. Results The screening coverage in Brazil was of 79.4% (95% confidence interval [95%CI]: 78.4-80.3), showing significant differences between the different states of the country, with the highest rate in the state of Roraima (86...
August 7, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28776947/racial-disparities-in-the-utilization-of-preventive-health-services-among-older-women-with-early-stage-endometrial-cancer-enrolled-in-medicare
#7
Jovana Y Martin, Melissa A Schiff, Noel S Weiss, Renata R Urban
To assess differences in the receipt of preventive health services by race/ethnicity among older women with endometrial cancer enrolled in Medicare, we conducted a retrospective population-based cohort study of women diagnosed with endometrial cancer from 2001 to 2011 in the Surveillance Epidemiology and End Results (SEER)-Medicare database. Women with stage I or II endometrial cancer of epithelial origin were included. The exposure was race/ethnicity (Non-Hispanic [NH] White, NH Black, Hispanic, and NH Asian/Pacific Islander [PI])...
August 4, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28766222/breast-cancer-disparities-socioeconomic-factors-versus-biology
#8
Lisa A Newman
Disparities in poverty and health care access barriers have a negative impact on the health and wellness of population subsets that bear a disproportionate share of these socioeconomic disadvantages, such as African Americans and Hispanic/Latina Americans. The more advanced stage distribution of breast cancer in these two population subsets is likely related to imbalance in distribution of socioeconomic resources in the United States. However, differences in the breast cancer burden of population subsets defined by racial/ethnic identity are also influenced by race/ethnicity-associated variation in tumor biology and hereditary susceptibility...
August 1, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28764733/associations-of-cause-specific-mortality-with-area-level-deprivation-and-travel-time-to-health-care-in-france-from-1990-to-2007-a-multilevel-analysis
#9
Walid Ghosn, Gwenn Menvielle, Stéphane Rican, Grégoire Rey
BACKGROUND: It is now widely accepted that social and physical environment participate in shaping health. While mortality is used to guide public health policies and is considered as a synthetic measure of population health, few studies deals with the contextual features potentially associated with mortality in a representative sample of an entire country. This paper investigates the possible role of area deprivation (FDep99) and travel time to health care on French cause-specific mortality in a proper multilevel setting...
August 2, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28759883/challenges-to-the-census-international-trends-and-a-need-to-consider-public-health-benefits
#10
REVIEW
R T Wilson, S H Hasanali, M Sheikh, S Cramer, G Weinberg, A Firth, S H Weiss, C L Soskolne
The Canadian government decision to cancel the mandatory long-form census in 2010 (subsequently restored in 2015), along with similar discussions in the United Kingdom (UK) and the United States of America (USA), have brought the purpose and use of census data into focus for epidemiologists and public health professionals. Policy decision-makers should be well-versed in the public health importance of accurate and reliable census data for emergency preparedness planning, controlling disease outbreaks, and for addressing health concerns among vulnerable populations including the elderly, low-income, racial/ethnic minorities, and special residential groups (e...
July 28, 2017: Public Health
https://www.readbyqxmd.com/read/28759121/health-care-disparities-among-octogenarians-and-nonagenarians-with-stage-ii-and-iii-rectal-cancer
#11
Richard J Cassidy, Jeffrey M Switchenko, En Cheng, Renjian Jiang, Jaymin Jhaveri, Kirtesh R Patel, Daniel G Tanenbaum, Maria C Russell, Conor E Steuer, Theresa W Gillespie, Mark W McDonald, Jerome C Landry
BACKGROUND: Octogenarians and nonagenarians with stage II/III rectal adenocarcinomas are underrepresented in the randomized trials that have established the standard-of-care therapy of preoperative chemoradiation followed by definitive resection (ie, chemoradiation and then surgery [CRT+S]). The purpose of this study was to evaluate the impact of therapies on overall survival (OS) for patients with stage II/III rectal cancers and determine predictors of therapy within the National Cancer Data Base (NCDB)...
July 31, 2017: Cancer
https://www.readbyqxmd.com/read/28756413/migration-and-work-in-postwar-australia-mortality-profile-comparisons-between-australian-and-italian-workers-exposed-to-blue-asbestos-at-wittenoom
#12
Alison Reid, Enzo Merler, Susan Peters, Nimashi Jayasinghe, Vittoria Bressan, Peter Franklin, Fraser Brims, Nicholas H de Klerk, Arthur W Musk
OBJECTIVES: Three hundred and thirty thousand Italians arrived in Australia between 1945 and 1966, many on assisted passage schemes where the worker agreed to a 2-year unskilled employment contract. Italians were the largest of 52 migrant groups employed at the Wittenoom blue asbestos mining and milling operation. We compare mortality from asbestos-related diseases among Italian and Australian workers employed at Wittenoom. METHODS: A cohort of 6500 male workers was established from employment records and followed up at state and national mortality and cancer registries...
July 29, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28753845/variability-of-sex-disparities-in-cancer-incidence-over-30-years-the-striking-case-of-kidney-cancer
#13
Ghislaine Scelo, Peng Li, Estelle Chanudet, David C Muller
It is well established that men are at higher risk of most non-sex-specific cancers than women, but there has been surprisingly little research investigating these differences. This is possibly because differences in exposure to established risk factors and hypothesised protection by female sex hormones are thought to account for the totality of the sex differences. These explanations remain somewhat speculative, as the magnitude of the sex ratio in cancer incidence has not been systematically studied, with no quantitative estimate of the variability of the sex ratio across countries, age groups, and periods of diagnosis...
January 31, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28739629/charting-the-future-of-cancer-health-disparities-research-a-position-statement-from-the-american-association-for-cancer-research-the-american-cancer-society-the-american-society-of-clinical-oncology-and-the-national-cancer-institute
#14
Blase N Polite, Lucile L Adams-Campbell, Otis W Brawley, Nina Bickell, John M Carethers, Christopher R Flowers, Margaret Foti, Scarlett Lin Gomez, Jennifer J Griggs, Christopher S Lathan, Christopher I Li, J Leonard Lichtenfeld, Worta McCaskill-Stevens, Electra D Paskett
No abstract text is available yet for this article.
July 24, 2017: Cancer Research
https://www.readbyqxmd.com/read/28738945/disparities-in-the-care-of-differentiated-thyroid-cancer-in-the-united-states-exploring-the-national-cancer-database
#15
Kathryn Jaap, Rebekah Campbell, James Dove, Marcus Fluck, Marie Hunsinger, Jeffrey Wild, Tania Arora, Mohsen Shabahang, Joseph Blansfield
Differentiated thyroid cancer (DTC) treatment is multifaceted, and may be influenced by socioeconomic factors. The goal of this study is to examine disparities in DTC treatment. DTC patients from 1998 to 2012 were identified using the National Cancer Database. DTC was identified in 262,041 patients. The mean age was 48.2. The majority of patients (52%) received care at Comprehensive Community Cancer Programs (CCCPs). Total thyroidectomy was less common at Community Cancer Programs (CCPs) [odds ratio (OR): 0...
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28738442/charting-the-future-of-cancer-health-disparities-research-a-position-statement-from-the-american-association-for-cancer-research-the-american-cancer-society-the-american-society-of-clinical-oncology-and-the-national-cancer-institute
#16
Blase N Polite, Lucile L Adams-Campbell, Otis W Brawley, Nina Bickell, John M Carethers, Christopher R Flowers, Margaret Foti, Scarlett Lin Gomez, Jennifer J Griggs, Christopher S Lathan, Christopher I Li, J Leonard Lichtenfeld, Worta McCaskill-Stevens, Electra D Paskett
No abstract text is available yet for this article.
July 24, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28737975/charting-the-future-of-cancer-health-disparities-research-a-position-statement-from-the-american-association-for-cancer-research-the-american-cancer-society-the-american-society-of-clinical-oncology-and-the-national-cancer-institute
#17
Blase N Polite, Lucile L Adams-Campbell, Otis W Brawley, Nina Bickell, John M Carethers, Christopher R Flowers, Margaret Foti, Scarlett Lin Gomez, Jennifer J Griggs, Christopher S Lathan, Christopher I Li, J Leonard Lichtenfeld, Worta McCaskill-Stevens, Electra D Paskett
No abstract text is available yet for this article.
July 24, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28733787/gatekeepers-perceptions-of-the-quality-and-availability-of-services-for-breast-and-cervical-cancer-patients-in-the-english-speaking-windward-islands-an-exploratory-investigation
#18
Kamilah B Thomas-Purcell, Will L Tarver, Christine Richards, Marva Primus-Joseph
PURPOSE: Although extensive screening services for breast and cervical cancers are available in the Caribbean, these cancers continue to be the leading causes of cancer death among women in this region. The purpose of this study was to determine the quality and availability of breast and cervical cancer treatment care and support services from the perspective of the gatekeepers who provide care for the patients in the Windward Islands of Dominica, Grenada, St Lucia, and St. Vincent. METHODS: A qualitative research design using semi-structured, in-depth interviews was used to gather data from gatekeepers who provided oncology prevention and care services to patients for at least one year...
July 21, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28726040/assessing-predicted-age-specific-breast-cancer-mortality-rates-in-27-european-countries-by-2020
#19
R Clèries, R M Rooney, M Vilardell, J A Espinàs, T Dyba, J M Borras
BACKGROUND: We assessed differences in predicted breast cancer (BC) mortality rates, across Europe, by 2020, taking into account changes in the time trends of BC mortality rates during the period 2000-2010. METHODS: BC mortality data, for 27 European Union (EU) countries, were extracted from the World Health Organization mortality database. First, we compared BC mortality data between time periods 2000-2004 and 2006-2010 through standardized mortality ratios (SMRs) and carrying out a graphical assessment of the age-specific rates...
July 19, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28721898/radiation-treatment-time-and-overall-survival-in-locally-advanced-non-small-cell-lung-cancer
#20
Matthew T McMillan, Eric Ojerholm, Vivek Verma, Kristin A Higgins, Sunil Singhal, Jarrod D Predina, Abigail T Berman, Surbhi Grover, Cliff G Robinson, Charles B Simone
PURPOSE: Prolonged radiation treatment (RT) time (RTT) has been associated with worse survival in several malignancies. The present study investigated whether delays during RT are associated with overall survival (OS) in non-small cell lung cancer (NSCLC). METHODS AND MATERIALS: The National Cancer Database was queried for patients with stage III NSCLC who had received definitive concurrent chemotherapy and fractionated RT to standard doses (59.4-70.0 Gy) and fractionation from 2004 to 2013...
August 1, 2017: International Journal of Radiation Oncology, Biology, Physics
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