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https://www.readbyqxmd.com/read/30343553/ginseng-berry-extract-increases-nitric-oxide-level-in-vascular-endothelial-cells-and-improves-cgmp-expression-and-blood-circulation-in-muscle-cells
#1
Cho In-Ho, Kang Byung-Woo, Park Yun-Jae, Lee Han-Joo, Park Sok, Lee Namju
PURPOSE: The purpose of this study was to determine whether ginseng berry extract improves blood circulation by regulating vasodilator expression in exposed to tumor necrosis factor alpha (TNF-α)-exposed endothelial cells and muscle cells. METHODS: Nitric oxide (NO) and cGMP levels in human umbilical vein endothelial cells (HUVECs) and A7r5 cells exposed to ginseng berry extract were investigated. Based on the in vitro results, healthy participants were treated with ginseng berry extract for 4 weeks and then a non-invasive vascular screening device was used to confirm the improvement of blood circulation...
September 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/30343443/a-multi-approach-lake-habitat-survey-method-for-impact-assessment-in-two-heavily-modified-lakes-a-case-of-two-northern-greek-lakes
#2
Dionissis Latinopoulos, Chrysoula Ntislidou, Ifigenia Kagalou
Despite hydromorphological pressure assessment is required by the European Water Framework Directive (WFD), there is not one commonly accepted method for this purpose. The extent of habitat alteration and naturalness loss is a major issue especially for heavily modified water bodies (HMWBs) in terms of their maximum ecological potential designation. In this research, a broadly used methodology in Central and Northern Europe, Lake Habitat Survey (LHS), is tested for the first time in Greece in two natural urban shallow lakes to estimate the extent of habitat modification and hydromorphological alteration...
October 20, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/30343406/challenges-in-the-treatment-of-fibrodysplasia-ossificans-progressiva
#3
REVIEW
Kardelen Gencer-Atalay, Ekim Can Ozturk, Ilker Yagci, Pinar Ata, Kenan Delil, Zerrin Ozgen, Gulseren Akyuz
Fibrodysplasia ossificans progressiva (FOP), is a rare autosomal dominant connective tissue disease with a prevalence of 1 in 2 million. It is characterized by congenital foot deformities and multiple heterotopic ossifications in fibrous tissue. It usually starts with painful soft tissue swellings occurring with attacks at the ages of three or four. The attacks develop spontaneously or after minor trauma, and gradually turn into heterotopic ossifications that cause joint limitations, growth defects, skeletal deformities and chronic pain...
October 20, 2018: Rheumatology International
https://www.readbyqxmd.com/read/30343210/patients-with-surgical-wounds-healing-by-secondary-intention-a-prospective-cohort-study
#4
I C Chetter, A V Oswald, E McGinnis, N Stubbs, C Arundel, H Buckley, K Bell, J C Dumville, N A Cullum, M O Soares, P Saramago
BACKGROUND: Surgical wounds healing by secondary intention can be difficult and costly to manage and are profoundly under researched. This prospective inception, cohort study aimed to derive a better understanding of surgical wounds healing by secondary intention and to facilitate the design of future research investigating effective treatments. OBJECTIVES: To investigate the clinical characteristics of patients with surgical wounds healing by secondary intention and the surgeries that preceded their wounds; to clearly delineate the clinical outcomes of these patients, specifically focusing on time to wound healing and its determinants; to explore the types of treatments for surgical wounds healing by secondary intention; and to assess the impact surgical wounds healing by secondary intention have on patients' quality of life...
September 18, 2018: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/30342989/a-case-of-iliac-aneurysm-with-persistent-sciatic-artery-treated-by-endovascular-aneurysm-repair-evar
#5
Yuki Orimoto, Hiroyuki Ishibashi, Ikuo Sugimoto, Tetsuya Yamada, Yuki Maruyama, Makiyo Hagihara, Tsuneo Ishiguchi
A persistent sciatic artery (PSA) is a rare congenital vascular anomaly that occurs in approximately 0.01 to 0.06% of the population. We encountered a patient with aneurysms in the common iliac-internal iliac artery continuous to an occluded right PSA. The patient was an 85-year-old male in whom intermittent claudication of the right lower limb appeared 3 months ago. The right ankle brachial index (ABI) was 0.48. On contrast CT, the right PSA was present and was occluded over the popliteal artery. The right superficial femoral artery was hypoplastic...
October 18, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/30342917/dorsal-suspension-for-morton-s-neuroma-a-comparison-with-neurectomy
#6
Jae Hwang Song, Chan Kang, Deuk Soo Hwang, Dong Hun Kang, Yong Hwan Kim
BACKGROUND: The purpose of this study was to investigate and compare the clinical outcomes of dorsal suspension with those of neurectomy for the treatment of Morton's neuroma. METHODS: We conducted a retrospective study of dorsal suspension and neurectomy group. The dorsal suspension was performed by dorsal transposition of neuroma over the dorsal transverse ligament after neurolysis. The visual analog scale (VAS), the Foot and Ankle Ability Measure (FAAM), postoperative satisfaction, and complications were evaluated...
October 5, 2018: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/30342716/low-frequency-of-staphylococcus-aureus-in-lower-extremity-skin-and-soft-tissue-infections
#7
Farah Tanveer, Ashish Bhargava, Kathleen Riederer, Leonard B Johnson, Riad Khatib
BACKGROUND: Staphylococcus aureus is often implicated in skin/soft tissue infections (SSTI). However, SSTI at sites of pressure necrosis and peripheral vascular disease (PVD) are often polymicrobial. The frequency of S aureus in these infections is uncertain. METHODS: We retrospectively reviewed culture results from adults (January 1, 2015-March 31, 2017), evaluated their records and selected SSTI in lower extremities. The patient demographics, comorbidities, characteristics and culture results were recorded...
September 21, 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30342663/prenatal-diagnosis-of-a-familial-1q21-1-q21-2-microdeletion-in-a-fetus-with-polydactyly-of-left-foot-on-prenatal-ultrasound
#8
Chih-Ping Chen, Shu-Yuan Chang, Yen-Ni Chen, Schu-Rern Chern, Peih-Shan Wu, Shin-Wen Chen, Shih-Ting Lai, Tzu-Yun Chuang, Chien-Wen Yang, Li-Feng Chen, Wayseen Wang
OBJECTIVE: We present prenatal diagnosis of a familial 1q21.1-q21.2 microdeletion in a fetus with polydactyly of left foot on prenatal ultrasound. CASE REPORT: A 30-year-old, gravida 2, para 1, woman underwent amniocentesis at 22 weeks of gestation because of fetal polydactyly of left foot and echogenic heart foci on prenatal ultrasound. She and her husband and the 2-year-old son were healthy, and there was no family history of mental disorders, skeletal abnormalities and congenital malformations...
October 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/30342526/initial-stability-and-stress-distribution-of-ankle-arthroscopic-arthrodesis-with-three-kinds-of-2-screw-configuration-fixation-a-finite-element-analysis
#9
Min Zhu, Cheng-Song Yuan, Zhong-Min Jin, Yun-Jiao Wang, You-Xing Shi, Zhi-Jin Yang, Kanglai Tang
BACKGROUND: Arthroscopic ankle arthrodesis (AAA) is recognized as the standard treatment for the end-stage ankle arthritis. Two-screw configuration fixation is a typical technique for AAA; however, no consensus has been reached on how to select most suitable inserted position and direction. For better joint reduction, we developed a new configuration (2 home run-screw configuration: 2 screws are inserted from the lateral-posterior and medial-posterior malleolus into the talar neck) and investigated whether it turned out to be better than the other commonly used 2-screw configurations...
October 20, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/30342380/suture-button-fixation-and-anterior-inferior-tibiofibular-ligament-augmentation-with-suture-tape-for-syndesmosis-injury-a-biomechanical-cadaveric-study
#10
Hiroaki Shoji, Atsushi Teramoto, Daisuke Suzuki, Yohei Okada, Yuzuru Sakakibara, Takashi Matsumura, Tomoyuki Suzuki, Kota Watanabe, Toshihiko Yamashita
BACKGROUND: Suture-button (SB) fixation has been widely performed for syndesmosis injuries, but it has been reported unstable in some biomechanical studies. The purpose of this study was to evaluate the stability of the syndesmosis using SB fixation with anterior inferior tibiofibular ligament augmentation using suture-tape (ST). METHODS: Eight normal fresh-frozen cadaveric legs were used. After initial tests of intact and injured models, SB fixation, SB fixation with ST augmentation, ST augmentation alone, and screw fixation were performed sequentially for each specimen...
October 12, 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/30342379/effects-of-static-stretching-on-mechanical-properties-and-collagen-fiber-orientation-of-the-achilles-tendon-in-vivo
#11
Keitaro Kubo
BACKGROUND: The study was designed to examine changes in tendon properties measured during ramp and ballistic contractions after static stretching and to elucidate the relationship between stretching-induced changes in tendon properties (particularly hysteresis) and collagen fiber orientation. METHODS: Thirteen males performed static stretching, in which the ankle was passively flexed to 36° dorsiflexion and remained stationary for 10 min. Before and after stretching, the stiffness and hysteresis of tendon structures in the medial gastrocnemius muscle were measured using ultrasonography during ramp and ballistic contractions...
October 16, 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/30342230/are-accelerometer-measures-of-temporal-patterns-of-static-standing-associated-with-lower-extremity-pain-among-blue-collar-workers
#12
Francisco Locks, Nidhi Gupta, Pascal Madeleine, Marie Birk Jørgensen, Ana Beatriz Oliveira, Andreas Holtermann
BACKGROUND: Pain in the lower extremities is common among blue-collar workers, with prolonged static standing as a potential risk factor. However, little is known about the association between diurnal accelerometer measures of static standing and pain in the lower extremities, and the potential importance of temporal patterns of static standing for this association. RESEARCH QUESTION: We aimed to investigate the cross-sectional association between accelerometer measures of total static standing time and temporal patterns (bout duration) of static standing (short: 0-5 min; moderate: >5-10 min; and long bouts: >10 min) during total day, work and leisure and pain intensity (on a 0-10 scale) in hips, knees and feet/ankles...
October 10, 2018: Gait & Posture
https://www.readbyqxmd.com/read/30342213/infection-of-prosthetic-patches-after-femoral-endarterectomy-an-unreported-complication
#13
Paolo Sapienza, Filippo Napoli, Elvira Tartaglia, Luigi Venturini, Antonio V Sterpetti, Gioia Brachini, Sergio Gazzanelli, Andrea Mingoli
BACKGROUND: Femoral prosthetic patch is a surgical procedure frequently used to treat atherosclerotic lesions involving femoral artery bifurcation. Even though it is an easy to perform procedure, surgical management of complications, first of all graft infection, may be challenging, with a high morbidity and mortality risk for patients. We report our experience on surgical treatment of femoral patch infection. MATERIALS AND METHODS: Between April 2012 and April 2018, 26 patients (26 limbs) were referred to the Emergency Department at our Institution, for the treatment of femoral prosthetic patch infection...
October 17, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/30342131/recent-advancements-in-biopolymer-and-metal-nanoparticle-based-materials-in-diabetic-wound-healing-management
#14
REVIEW
Veena Vijayakumar, Sushanta K Samal, Smita Mohanty, Sanjay K Nayak
Currently, diabetes mellitus (DM) accelerated diabetic foot ulcer (DFU) remains vivacious health problem related with delayed healing and high amputation rates which leads to enormous clinical obligation. Keeping in view of the foregoing, researchers have been made in their efforts to develop novel materials which accelerate delayed wound healing in the diabetic patient and reduce the adversative influences of DFUs. The most prominent materials used for the wound healing application have biocompatibility, low cytotoxicity, excellent biodegradable properties, and antimicrobial activity properties...
October 17, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/30341717/suggested-mechanisms-underlying-pollen-wall-development-in-ambrosia-trifida-asteraceae-heliantheae
#15
Nina Gabarayeva, Svetlana Polevova, Valentina Grigorjeva, Elena Severova, Olga Volkova, Stephen Blackmore
By a detailed ontogenetic study of Ambrosia trifida pollen, tracing each stage of development with TEM, we aim to understand the establishment of the pollen wall and to unravel the mechanisms underlying sporoderm development. The main steps of exine ontogeny in Ambrosia trifida, observed in the microspore periplasmic space, are as follows: spherical units, gradually transforming into columns, then to rod-like units; the appearance of the initial reticulate tectum; growth of columellae under the tectum and initial sporopollenin accumulation on them; the appearance of the endexine lamellae, first in fragments, then in long laminae; the cessation of the glycocalyx growth and its detachment from the plasma membrane, resulting in the appearance of gaps; massive accumulation of sporopollenin on the tectum, columellae, and endexine, and the appearance of the foot layer at the young post-tetrad stage, accompanied by establishment of caveae in sites of the former gaps; and final massive sporopollenin accumulation...
October 19, 2018: Protoplasma
https://www.readbyqxmd.com/read/30341712/thalidomide-and-neurotrophism
#16
REVIEW
Judith R Soper, S Fiona Bonar, Dudley J O'Sullivan, Janet McCredie, Hans-Georg Willert
BACKGROUND: Following the thalidomide disaster (1958-62), Henkel and Willert analysed the pattern of dysmelia in the long bones (J Bone Joint Surg Br. 51:399-414, 1969) and the extremities, Willert and Henkel (Z Orthop Ihre Grenzgeb. 107:663-75, 1970). Willert's material from deformed extremities is re-examined here asking "How does thalidomide reduce the skeleton?" MATERIALS AND METHODS: We reviewed the original data collection of Willert and Henkel (Z Orthop Ihre Grenzgeb...
October 19, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/30341641/osteoid-osteoma-multimodality-imaging-with-focus-on-hybrid-imaging
#17
REVIEW
Ujwal Bhure, Justus E Roos, Klaus Strobel
Osteoid osteoma is a painful, benign, osteoblastic lesion that occurs in younger patients and affects the extremities or the axial skeleton. While plain film findings may suggest the diagnosis, in complex anatomical regions such as the spine, pelvis, wrist and foot advanced imaging modalities are often required. A typical nidus surrounded by sclerosis or cortical thickening characterizes osteoid osteoma on plain radiography and CT. MR is the cross-sectional imaging modality of choice for most musculoskeletal disorders...
October 19, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30341352/implicit-time-place-conditioning-alters-per2-mrna-expression-selectively-in-striatum-without-shifting-its-circadian-clocks
#18
Tenjin C Shrestha, Karolína Šuchmanová, Pavel Houdek, Alena Sumová, Martin R Ralph
Animals create implicit memories of the time of day that significant events occur then anticipate the recurrence of those conditions at the same time on subsequent days. We tested the hypothesis that implicit time memory for daily encounters relies on the setting of the canonical circadian clockwork in brain areas involved in the formation or expression of context memories. We conditioned mice to avoid locations paired with a mild foot shock at one of two Zeitgeber times set 8 hours apart. Place avoidance was exhibited only when testing time matched the prior training time...
October 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30341326/16s-rrna-amplicon-sequencing-reveals-a-polymicrobial-nature-of-complicated-claw-horn-disruption-lesions-and-interdigital-phlegmon-in-dairy-cattle
#19
V Bay, B Griffiths, S Carter, N J Evans, L Lenzi, R C Bicalho, G Oikonomou
Lameness represents an intractable problem for the dairy industry. Complicated claw horn disruption lesions, interdigital hyperplasia, and interdigital phlegmon are important lameness causing foot lesions. Their aetiology is multifactorial, but infectious processes are likely implicated in disease pathogenesis. Our aim was to investigate the bacterial profiles of these lesions using 16S rRNA gene sequencing of samples obtained from 51 cattle across ten farms in the UK. In this study, interdigital hyperplasia, interdigital hyperplasia with signs of interdigital dermatitis, interdigital phlegmon, complicated sole ulcers, complicated toe ulcers lesions, and complicated white line lesions were investigated; corresponding healthy skin control samples were also analysed...
October 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30341195/learning-more-about-scaly-leg-and-tassel-foot
#20
(no author information available yet)
Georgina Mills explains how members of the public have contributed to investigations of leg lesions in garden finches.
October 20, 2018: Veterinary Record
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