Eseosa T Ighodaro, Ryan K Shahidehpour, Adam D Bachstetter, Erin L Abner, Ruth S Nelson, David W Fardo, Andy Y Shih, Roger I Grant, Janna H Neltner, Frederick A Schmitt, Gregory A Jicha, Richard J Kryscio, Donna M Wilcock, Linda J Van Eldik, Peter T Nelson
Cerebrovascular pathologies other than frank infarctions are commonly seen in aged brains. Here, we focus on multi-lumen vascular profiles (MVPs), which are characterized by multiple vessel lumens enclosed in a single vascular channel. Little information exists on the prevalence, risk factors, and co-pathologies of MVPs. Therefore, we used samples and data from the University of Kentucky Alzheimer's Disease Research Center (n = 91), the University of Kentucky Pathology Department (n = 31), and the University of Pittsburgh Pathology Department (n = 4) to study MVPs...
August 28, 2023: Acta Neuropathologica Communications