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Oncologic radiology

Silvia Taralli, Valentina Scolozzi, Massimiliano Foti, Sara Ricciardi, Anna Rita Forcione, Giuseppe Cardillo, Maria Lucia Calcagni
PURPOSE: In oncological patients, 18 F-FDG PET/CT performance for pulmonary nodules' characterization is not well-established. Thus, the purpose of this study was to evaluate the 18 F-FDG PET/CT diagnostic performance in pulmonary nodules detected during follow-up in oncological patients and the relationship between malignancy and nodules' characteristics. METHODS: We retrospectively evaluated 182 pulmonary nodules (121 solitary, 61 multiple; mean size = 16...
December 8, 2018: European Journal of Nuclear Medicine and Molecular Imaging
Ruta Gupta, Ann Sandison, Bruce M Wenig, Lester D R Thompson
The International Collaboration on Cancer Reporting (ICCR) was established to internationally unify and standardize the pathologic reporting of cancers based on collected evidence, as well as to allow systematic multi-institutional intercountry data collection to guide cancer care in the future. Such collaborative efforts are particularly essential for developing an evidence base for rare neoplasms, or those with marked geographic variation in incidence, such as the tumors of the ear and the temporal bone. The ear and the temporal bone, including the external auditory canal and the middle and inner ear, with the closely associated facial nerve, internal carotid artery, and internal jugular vein, is one of the most complex anatomic structures in the head and neck...
November 30, 2018: Archives of Pathology & Laboratory Medicine
Ediel Valerio, Ana Goes, Mariana Andozia, Mauricio Amoedo, Gislaine Porto, Mauro Saieg
In about 25-30% of patients with primary renal cell carcinoma, metastasis is not uncommon and usually does not give rise to difficulties in diagnosis. However, its presentation as a subcutaneous mass following an elapse of several years after the initial diagnosis is not only uncommon but may be also mistaken for a thrombus in imaging studies due to its common high vascularization. We present here a case of a 70-year-old woman with an oncologic history of renal cell carcinoma who noticed after five years a mass in the auricular region radiologically suggestive of a vascular thrombus...
November 29, 2018: Diagnostic Cytopathology
Christoph Schroeder, Friedemann Geiger, Frank-André Siebert, René Baumann, Gunnar Bockelmann, Jürgen Schultze, Bernhard Kimmig, Jürgen Dunst, Razvan Galalae
PURPOSE: High-dose-rate brachytherapy (HDR-BT) for dose escalation in localized prostate cancer has been established as one standard treatment option. However, long-term results at followup (FU) ≥5 years are usually needed to ensure robustness of reported outcomes. Potential benefit of salvage therapy is, nevertheless, higher when relapse is diagnosed early. This study aimed to solve this dilemma by evaluating the prostate-specific antigen (PSA) nadir for early prediction of long-term biochemical control...
October 25, 2018: Brachytherapy
Susan Crisp, Krista Dawdy
Magnetic resonance imaging (MRI) uses a strong magnetic field to generate diagnostic images. This magnetic field has the potential to cause serious and even fatal injuries to patients undergoing scans and to personnel in the area. Ensuring awareness of MRI hazards and safety procedures through a formalized education and training program is integral in creating an MRI safety culture that protects patients and staff from harm. The aim of our project was to develop an accessible and interprofessional electronic e-module learning series to instill an MRI safety culture throughout the entire hospital...
March 2018: Journal of Medical Imaging and Radiation Sciences
Paul E Wallner, Kaled M Alektiar, Lane F Donnelly, John A Kaufman
OBJECTIVE: In 1998, the American Board of Radiology introduced the B. Leonard Holman Research Pathway (HRP) to initial certification for trainees in diagnostic radiology (DR) and radiation oncology (RO) motivated to pursue research-oriented careers in academic DR and RO. CONCLUSION: The HRP Committee anticipated that there would be a relatively even distribution between DR and RO participants, but with 18 years of experience that has not been the case. This article focuses on the HRP and DR...
November 26, 2018: AJR. American Journal of Roentgenology
P-H Savoie, T Murez, A Fléchon, P Sèbe, L Rocher, P Camparo, N Morel-Journel, L Ferretti, A Méjean
OBJECTIVE: To update French oncology guidelines concerning adrenal cancer. METHODS: Comprehensive Medline search between 2016 and 2018 upon diagnosis, treatment and follow-up of adrenal cancer to update 2013 guidelines. Level of evidence was evaluated according to AGREE-II. RESULTS: Adrenal cancers are mainly represented by adrenocortical carcinomas (AC), malignant pheochromocytomas (MPC) and adrenal metastases (AM). Medical background of these tumors is either the exploration of hormonal or tumor symptoms, or an adrenal incidentaloma...
November 2018: Progrès en Urologie
Rut Cañas, Isabel Linares, Ferran Guedea, Miguel Ángel Berenguer
Radiological Oncology, like the rest of medical specialties, is beginning to provide can personalized therapies. The ongoing scientific advances enable a great degree of precision in diagnoses and therapies. To fight cancer, from a radiotherapy unit, requires up-to-date equipment, professionals with different specialties working in synchrony (doctors, physicists, biologists, etc.) and a lot of research. Some of the new therapeutic tendencies are immunotherapy, nanoparticles, gene therapy, biomarkers, artificial intelligence, etc...
January 2019: Reports of Practical Oncology and Radiotherapy
Amita Shukla-Dave, Nancy A Obuchowski, Thomas L Chenevert, Sachin Jambawalikar, Lawrence H Schwartz, Dariya Malyarenko, Wei Huang, Susan M Noworolski, Robert J Young, Mark S Shiroishi, Harrison Kim, Catherine Coolens, Hendrik Laue, Caroline Chung, Mark Rosen, Michael Boss, Edward F Jackson
Physiological properties of tumors can be measured both in vivo and noninvasively by diffusion-weighted imaging and dynamic contrast-enhanced magnetic resonance imaging. Although these techniques have been used for more than two decades to study tumor diffusion, perfusion, and/or permeability, the methods and studies on how to reduce measurement error and bias in the derived imaging metrics is still lacking in the literature. This is of paramount importance because the objective is to translate these quantitative imaging biomarkers (QIBs) into clinical trials, and ultimately in clinical practice...
November 19, 2018: Journal of Magnetic Resonance Imaging: JMRI
Ashwin Kumaria, Alice Teale, Girish V Kulkarni, Harshal A Ingale, Donald C Macarthur, Iain J A Robertson
We present the case of a 65 year old gentleman who underwent craniotomy and debulking of a left temporal glioblastoma multiforme (GBM). Post-operatively he received chemotherapy and radiotherapy with good response demonstrated on interval MRI scans. At 17 months post-diagnosis and in the absence of clinical or radiological recurrence, he presented with respiratory distress. He was found to have an exudative right-sided pleural effusion, nodular pleural thickening, a hilar mass and associated lymphadenopathy...
November 19, 2018: British Journal of Neurosurgery
András Bibok, Pál Ákos Deák, Attila Doros
The transplantation of the abdominal organs has a major role in the treatment of several diseases. All subspecialities affected with the transplantation showed a rapid development in the last decades. The cooperation of the specialists of different segments of medicine provides the success of organ transplantation. Teamwork is necessary throughout the whole process starting from securing the technical background and proper human workforce, followed by the lifelong management of organs and recipients as well...
November 2018: Orvosi Hetilap
Kia Nikoomanesh, Julian Choi, Sarkis Arabian
BACKGROUND: Small cell lung carcinoma (SCLC) is one of the deadliest forms of lung cancer due to its poor prognosis upon diagnosis, rapid doubling time, and affinity for metastasis. As 60-70% of patients with SCLC have disseminated disease upon presentation, it is imperative to determine the extent of disease burden for treatment. As a neuroendocrine carcinoma, clinicians must pay close attention to abnormal findings in a smoker that could lead to earlier diagnosis and better prognostication...
November 14, 2018: BMC Pulmonary Medicine
Peter F Horstmann, Werner H Hettwer, Michael M Petersen
PURPOSE: The management of bone defects following simple curettage of bone tumors is controversial and in light of the numerous emerging substitutes for bone grafts, we wished to review and report our experience with the use of cancellous allograft bone in the treatment of benign and borderline bone tumors. METHODS: We reviewed the medical records of 164 consecutive patients with benign or borderline bone tumors treated with simple curettage at our orthopedic oncology center between 2009 and 2013...
May 2018: Journal of Orthopaedic Surgery
Walid A Ebeid, Bahaa Z Hasan, Ismail T Badr, Mohamed K Mesregah
BACKGROUND: Chondroblastoma is a rare cartilaginous benign bone tumor that commonly arises in long bones of young people. Surgical management is the primary treatment of choice for chondroblastoma and it entails adequate intralesional curettage alone or in combination with adjuvants. This study was performed to describe the epidemiological characteristics and clinical and radiologic results of intralesional curettage of chondroblastoma. METHODS: This was a retrospective study which included an analysis of 91 patients with chondroblastoma who were treated with intralesional curettage and were followed up between 1994 and 2014 for at least 3 years...
November 8, 2018: Journal of Pediatric Orthopedics
Le Qin, Qiyuan Bao, Jie Chen, Lianjun Du, Fuhua Yan, Yong Lu, Caixia Fu, Weibin Zhang, Yuhui Shen
Objective: To explore the imaging features of local recurrences (LRs) based on magnetic resonance imaging (MRI) after oncological orthopaedic surgery with prosthesis reconstruction. Methods: A total of 78 cases totalling 157 scans were retrospectively reviewed. Patients with nodule/mass-like signals were retrospectively classified into LR, infectious pseudotumour, and asymptomatic pseudotumour according to clinicopathological data. LRs were histologically confirmed, and the patients without recurrences were followed up for at least 2 years...
October 2018: Journal of Orthopaedic Translation
Jeroen Swinnen, Machteld Keupers, Julie Soens, Matthias Lavens, Sandra Postema, Chantal Van Ongeval
OBJECTIVES: The article summarises the available guidelines on breast imaging surveillance after curative treatment for locoregional breast cancer. METHODS: A systematic review of practice guidelines published from 1 January 2007 to 1 January 2017 was performed according to PRISMA methodology. The search was conducted for the EMBASE, MEDLINE, Cochrane and Centre for Reviews and Dissemination databases. On 8 July 2018, all included guidelines were updated to the most recent version...
November 8, 2018: Insights Into Imaging
Shao Hui Huang, Ezra Hahn, Raymond K Tsang, Zhi-Jian Chen, Brian O'Sullivan
Transoral surgery (TOS) and IMRT represent two primary local ablative treatment modalities for oropharyngeal cancer (OPC). The choice of one over the other represents an interplay between the chance of cure vs risk of late sequelae. HPV-mediated (HPV+) OPC patients generally have excellent outcomes, especially in TNM-8 stage I disease. Controversies exist over which treatment has a more favorable toxicity profile and equal efficacy in the management of this population. Non-randomized retrospective data show comparable oncological and functional outcomes between TOS-based vs IMRT-based treatment for this disease...
November 2018: Oral Oncology
Manoj Pandey, Senniappan Karthikeyan, Deepika Joshi, Mohan Kumar, Mridula Shukla
BACKGROUND: The lymphatic spread from the cancers of the oral cavity follows an orderly progression and involvement of lower nodes without involvement of upper nodes and skip metastasis is rare. Selective neck dissections are increasingly being performed for node-positive patients; however, in node-negative patients the options of wait and watch, prophylactic radiotherapy, and prophylactic elective node dissections are debated. Quality of life and shoulder functions are important to choose the appropriate therapeutic modality...
November 8, 2018: World Journal of Surgical Oncology
Luis Hurtado Pardo, Javier A Cienfuegos, Javier Antoñanzas, Alberto Benito, Pablo Panadero, Joseba Salguero, Pablo Martí-Cruchaga, Gabriel Zozaya, Víctor Valentí, Fernando Pardo, Fernando Rotellar, José Luis Hernández Lizoáin
BACKGROUND: the aim of the present study was to analyze the clinicopathological features of patients undergoing pancreatic surgical resections due to cystic neoplasms of the pancreas. MATERIAL AND METHODS: demographic data, form of presentation, radiologic images and location of the tumors within the pancreas were analyzed. Data was also collected on the type of surgery (open/laparoscopic), postoperative complications and their severity and oncologic outcomes. RESULTS: eighty-two pancreatic resections were performed...
November 8, 2018: Revista Española de Enfermedades Digestivas
Xavier Buy, Vittorio Catena, Guilhem Roubaud, Amandine Crombe, Michèle Kind, Jean Palussiere
Occurrence of bone metastases is a common event in oncology. Bone metastases are associated with pain, functional impairment, and fractures, particularly when weight-bearing bones are involved. Management of bone metastases has been improved by the development of various interventional radiology consolidation techniques. Cementoplasty is based on injection of acrylic cement into a weakened bone to reinforce it and to control pain. This minimally invasive technique has proven its efficacy for flat bone submitted to compression forces...
October 2018: Seminars in Interventional Radiology
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