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Oncologic radiology

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https://www.readbyqxmd.com/read/30103752/case-report-synovial-sarcoma-of-the-axilla-with-brachial-plexus-involvement
#1
Ziyad M Mohaidat, Abed-Allah A Saleh, Salah Al-Gharaibeh, Ibrahim R Yousef
BACKGROUND: Synovial sarcoma is a rare soft tissue sarcoma which most commonly affects the extremities of young adults. Axilla involvement by this sarcoma is very rare especially with involvement of the brachial plexus. This combination adds to the challenge in approaching such tumors which might significantly affect survival and function. CASE PRESENTATION: Herein, we present a 48-year-old female patient who presented with an isolated painless lump in her right axilla...
August 13, 2018: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/30101009/impact-of-multidisciplinary-tumor-boards-on-patients-with-rectal-cancer
#2
REVIEW
Argyrios Ioannidis, Michael Konstantinidis, Sotirios Apostolakis, Christos Koutserimpas, Nikolaos Machairas, Konstantinos M Konstantinidis
Οncological outcomes in patients with primary rectal cancer have markedly improved over the last few years, mainly due to the widespread application of the total mesorectal excision technique. This improvement should also be largely attributed to multiple specialties, other than colorectal surgery, such as radiology, oncology and pathology. Therefore, a multimodal approach is key to efficient and appropriate rectal cancer management. Multidisciplinary tumor (MDT) boards have become an important asset for the management and treatment of patients with rectal cancer, and a number of studies published to date suggest the beneficial effect of the multidisciplinary approach on the management of such patients...
August 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/30099643/curettage-phenolization-and-cementation-in-paediatric-ewing-s-sarcoma-with-a-complete-radiological-response-to-neoadjuvant-chemotherapy
#3
Khodamorad Jamshidi, Mehdi Ramezan Shirazi, Abolfazl Bagherifard, Alireza Mirzaei
PURPOSE: Although wide resection is the standard treatment for Ewing's sarcoma (ES), it has complications especially in children. In this study, we compared the oncologic and functional outcomes of wide resection with extended curettage and local adjuvant therapy (phenolization and cementation), as a less extensive surgery for paediatric ES with a complete radiologic response to neoadjuvant chemotherapy. METHODS: Children aged ≤ ten years, with ES of non-expendable long-bones and complete radiologic response to neoadjuvant chemotherapy, were included in this case-control study...
August 11, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/30098069/diagnosis-of-invasive-fungal-diseases-in-haematology-and-oncology-2018-update-of-the-recommendations-of-the-infectious-diseases-working-party-of-the-german-society-for-hematology-and-medical-oncology-agiho
#4
REVIEW
Markus Ruhnke, Gerhard Behre, Dieter Buchheidt, Maximilian Christopeit, Axel Hamprecht, Werner Heinz, Claus-Peter Heussel, Marius Horger, Oliver Kurzai, Meinolf Karthaus, Jürgen Löffler, Georg Maschmeyer, Olaf Penack, Christina Rieger, Volker Rickerts, Jörg Ritter, Martin Schmidt-Hieber, Nikolai Schuelper, Stefan Schwartz, Andrew Ullmann, Jörg-Janne Vehreschild, Marie von Lilienfeld-Toal, Thomas Weber, Hans-H Wolf
Invasive fungal diseases (IFD) are a primary cause of morbidity and mortality in patients with haematological malignancies. These infections are mostly life-threatening and an early diagnosis and initiation of appropriate antifungal therapy are essential for the clinical outcome. Most commonly, Aspergillus and Candida species are involved. However, other Non-Aspergillus moulds are increasingly identified in case of documented IFD. For definite diagnosis of IFD, a combination of diagnostic tools have to be applied, including conventional mycological culture and non-conventional microbiological tests such as antibody / antigen and molecular tests, as well as histopathology and radiology...
August 11, 2018: Mycoses
https://www.readbyqxmd.com/read/30097235/immune-checkpoint-inhibitors-in-non-small-cell-lung-cancer-a-tool-to-improve-patients-selection
#5
REVIEW
Giuseppe Luigi Banna, Francesco Passiglia, Francesca Colonese, Stefania Canova, Jessica Menis, Alfredo Addeo, Antonio Russo, Diego Luigi Cortinovis
The identification of reliable predictive biomarkers of efficacy or resistance to immune-oncology (I-O) agents is a major issue for translational research and clinical practice. However, along with PDL1 and molecular features other clinical, radiological and laboratory factors can be considered for the selection of those patients who would not be the best candidate for immune-checkpoint inhibitors (ICPIs). We examined these factors, emerging from the results of currently available studies in non-small cell lung cancer (NSCLC), aiming to provide a useful and manageable tool which can help Oncologists in their everyday clinical practice...
September 2018: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/30097070/prospective-comparison-of-various-radiological-response-criteria-and-pathological-response-to-preoperative-chemotherapy-and-survival-in-operable-high-grade-soft-tissue-sarcomas-in-the-japan-clinical-oncology-group-study-jcog0304
#6
Kazuhiro Tanaka, Gakuto Ogawa, Junki Mizusawa, Norifumi Naka, Akira Kawai, Mitsuru Takahashi, Toru Hiruma, Yoshihiro Matsumoto, Hiroyuki Tsuchiya, Robert Nakayama, Hiroshi Hatano, Makoto Emori, Masami Hosaka, Yukihiro Yoshida, Junya Toguchida, Satoshi Abe, Kunihiro Asanuma, Ryohei Yokoyama, Hiroaki Hiraga, Tsukasa Yonemoto, Takeshi Morii, Seiichi Matsumoto, Akihito Nagano, Hideki Yoshikawa, Haruhiko Fukuda, Toshifumi Ozaki, Yukihide Iwamoto
BACKGROUND: Soft tissue sarcomas (STS) are rare malignant tumors. The efficacy of preoperative chemotherapy for STS is evaluated using various tumor size-based radiological response criteria. However, it is still unclear which set of criteria would show the best association with pathological response and survival of the patients with STS. METHODS: We compared radiological responses to preoperative chemotherapy for operable STS by the Response Evaluation Criteria in Solid Tumors (RECIST), modified RECIST, World Health Organization criteria, Japanese Orthopaedic Association criteria, and modified Choi criteria and analyzed the association with pathological response and survival using the data from the Japan Clinical Oncology Group (JCOG) study JCOG0304, a phase II clinical trial evaluating the efficacy of perioperative chemotherapy for STS in the extremities...
August 10, 2018: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/30095201/surgical-oncology-at-a-major-referral-center-in-ghana-burden-staging-and-outcomes
#7
Adam Gyedu, Cameron E Gaskill, Kwabena Agbedinu, Daniela Rebollo Salazar, T Peter Kingham
BACKGROUND AND OBJECTIVES: Outcome data after surgery for cancer in Sub-Saharan Africa are insufficient. We aimed to describe the presentation and outcomes of patients with solid cancers managed at a tertiary hospital in Ghana. METHODS: Records of cancer patients admitted to Komfo Anokye Teaching Hospital general surgery wards from 2013 to 2016 were reviewed for data on presentation, staging, management, and mortality. Patients discharged alive were followed-up by biannual telephone calls to establish their postdischarge status...
August 10, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/30089580/what-you-see-is-not-what-you-get-tools-for-a-non-radiologist-to-evaluate-image-quality-in-lung-cancer
#8
Evelyn E C de Jong, Lizza E L Hendriks, Wouter van Elmpt, Hester A Gietema, Paul A M Hofman, Dirk K M De Ruysscher, Anne-Marie C Dingemans
Medical images are an integral part of oncological patient records and they are reviewed by many different specialists. Therefore, it is important that besides imaging experts, other clinicians are also aware that the diagnostic value of a scan is influenced by the applied imaging protocol. Based on two clinical lung cancer trials, we experienced that, even within a study protocol, there is a large variability in imaging parameters, which has direct impact on the interpretation of the image. These two trials were: 1) the NTR3628 in which the added value of gadolinium magnetic resonance imaging (Gd-MRI) to dedicated contrast enhanced computed tomography (CE-CT) for detecting asymptomatic brain metastases in stage III non-small cell lung cancer (NSCLC) was investigated and 2) a sub-study of the NVALT 12 trial (NCT01171170) in which repeated 18 F-fludeoxyglucose positron emission tomography (18 F-FDG-PET) imaging for early response assessment was investigated...
September 2018: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/30083834/downstaging-with-localized-concurrent-chemoradiotherapy-can-identify-optimal-surgical-candidates-in-hepatocellular-carcinoma-with-portal-vein-tumor-thrombus
#9
Jae Uk Chong, Gi Hong Choi, Dai Hoon Han, Kyung Sik Kim, Jinsil Seong, Kwang-Hyub Han, Jin Sub Choi
BACKGROUND: Locally advanced hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) has a poor oncological outcome. This study evaluated the oncological outcomes and prognostic factors of surgical resection after downstaging with localized concurrent chemoradiotherapy (CCRT) followed by hepatic arterial infusion chemotherapy (HAIC). METHODS: From 2005 to 2014, 354 patients with locally advanced HCC underwent CCRT followed by HAIC. Among these patients, 149 patients with PVTT were analyzed...
August 6, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/30074292/the-status-of-radiation-oncology-teaching-in-australian-and-new-zealand-medical-schools
#10
Luke Nicholls, Ben Bravery, Revadhi Chelvjmirojah, Kate Shi, Minh Thi Tieu, Sandra Turner, Apsjmiro Windsor
INTRODUCTION: Radiation therapy is a core component of curative and palliative cancer treatment; however, its indications and benefits remain poorly understood across the medical profession. METHODS: An electronic survey focussing on curriculum content, teaching and assessment in radiation oncology and plans for curriculum change was developed. The Faculty of Radiation Oncology, Royal Australian and New Zealand College of Radiology (RANZCR) distributed the survey to all 24 Australian and New Zealand medical schools...
August 3, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/30062728/a-survey-of-stereotactic-radiation-therapy-in-veterinary-medicine
#11
Elizabeth M Dunfield, Michelle M Turek, Kevin A Buhr, Neil C Christensen
Radiotherapy plays an important role in curative and palliative cancer treatment. As a novel radiation delivery technique, stereotactic radiotherapy utilizes three-dimensional-conformal treatment planning, high-precision beam delivery technology, and patient specific position verification to target tumors, often in one to five high-dose fractions. Currently, there is no consensus about best stereotactic radiotherapy practices in veterinary radiotherapy. The objective of this study was to document the breadth of perspectives, techniques, and applications of stereotactic radiotherapy in veterinary medicine...
July 30, 2018: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/30062457/is-routine-mri-necessary-to-exclude-pathological-fractures-in-patients-with-an-oncological-history
#12
Daniel Wei Ren Seng, Ernest Beng Kee Kwek
INTRODUCTION: Magnetic resonance imaging (MRI) is the radiological modality of choice for diagnosing pathological fractures in situations of diagnostic uncertainty. With the increasing availability of MRI, we have observed a disturbing trend in utilising routine MRI scans to exclude pathological fractures in all patients with a history of cancer. The study objective was to determine if routine use of MRI scans in such patients is truly necessary and if other predictive factors can be utilised in lieu of the MRI scan...
July 30, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/30061004/efficacy-of-autologous-fat-transfer-for-the-correction-of-contour-deformities-in-the-breast-a-systematic-review-and-meta-analysis
#13
REVIEW
Todor K Krastev, Ghufran A H Alshaikh, Juliette Hommes, Andrzej Piatkowski, Rene R W J van der Hulst
BACKGROUND: Autologous fat transfer (AFT), also known as fat grafting or lipofilling, has already become a part of clinical practice for treating contour deformities of the breast, even though evidence regarding its efficacy is still lacking. This is the first meta-analysis on this subject, aimed to facilitate intuitive interpretation of the available data by clinicians, guideline committees and policy makers. METHODS: A literature search was performed on 1 September 2017 in PubMed, EMBASE and the Cochrane Library to identify all relevant studies...
June 8, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/30058782/endovascular-treatment-of-iatrogenic-arteriovenous-fistula-of-the-iliac-vessel
#14
Piotr Kaźmierski, Mirosław Wąsiewicz, Jarosław Chrząstek, Michał Pająk
BACKGROUND: Iatrogenic vascular injuries, due to the particular nature of such pathology, are associated with high morbidity and mortality in the postoperative period. OBJECTIVES: The objective of this study was to present a case of non-classic approach to the therapy of iatrogenic arteriovenous fistula. MATERIAL AND METHODS: We present a case of a 17-year old female patient admitted to the Department of Vascular, General and Oncologic Surgery (Copernicus Memorial Hospital, Łódź, Poland) due to an iatrogenic injury to the common iliac vein and artery, following neurosurgical intervention on the spine...
July 30, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/30054029/trends-in-interventional-radiology-through-the-eye-of-the-journal-of-vascular-and-interventional-radiology-a-27-year-history
#15
Jacob J Bundy, Anthony N Hage, Jeffrey Forris Beecham Chick, Joseph J Gemmete, Rajiv N Srinivasa, Eunjee Lee, Evan Johnson, Jawad Hussain, Michael Cline, Nishant Patel, Ravi N Srinivasa
PURPOSE: To report the quantity, manuscript types, geographic distribution of publications, and published content trends in a major interventional radiology journal over 27 years. MATERIALS AND METHODS: Available publication data from the Journal of Vascular and Interventional Radiology was collected via Scopus from November 1990 to November 2017. Quantity, manuscript type, geographic distribution, number of citations, and publication content were analyzed. RESULTS: 6925 papers were published in JVIR during the study period...
May 23, 2018: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/30050803/magnetic-resonance-imaging-mri-based-radiomics-for-prostate-cancer-radiotherapy
#16
REVIEW
Fei Yang, John C Ford, Nesrin Dogan, Kyle R Padgett, Adrian L Breto, Matthew C Abramowitz, Alan Dal Pra, Alan Pollack, Radka Stoyanova
In radiotherapy (RT) of prostate cancer, dose escalation has been shown to reduce biochemical failure. Dose escalation only to determinate prostate tumor habitats has the potential to improve tumor control with less toxicity than when the entire prostate is dose escalated. Other issues in the treatment of the RT patient include the choice of the RT technique (hypo- or standard fractionation) and the use and length of concurrent/adjuvant androgen deprivation therapy (ADT). Up to 50% of high-risk men demonstrate biochemical failure suggesting that additional strategies for defining and treating patients based on improved risk stratification are required...
June 2018: Translational Andrology and Urology
https://www.readbyqxmd.com/read/30050787/review-of-radiological-screening-programmes-for-breast-lung-and-pancreatic-malignancy
#17
REVIEW
Helena Barton, David Shatti, Charlotte Anne Jones, Mathuri Sakthithasan, Will W Loughborough
The premise of medical screening is to identify clinically occult disease, facilitating intervention at an early stage with the intention of improving prognosis. Identifying solid organ malignancy before nodal or distal metastases have occurred unanimously offers the best chance of successful radical treatment, thus there is clearly a potential significant mortality benefit for successful oncological screening programmes. However, the negative consequences of screening have to be considered, particularly the impact of intervening in asymptomatic populations...
June 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/30050395/laboratory-aspects-and-clinical-utility-of-bone-turnover-markers
#18
Harjit Pal Bhattoa
With an aging population, there is a marked increase in prevalence of metabolic bone diseases, especially osteoporosis. Perhaps the most dreaded complication of metabolic bone disease, fractures typically impose a huge burden on the ailing body and are associated with high co-morbidity and mortality. The consequent public health and socioeconomic burden warrant timely diagnosis, treatment and follow-up of these disorders. Knowing the limitations of radiological techniques, biochemical markers of bone turnover measurements come handy since the changes in their levels readily reflect bone physiology...
July 2018: EJIFCC
https://www.readbyqxmd.com/read/30049023/treatment-outcomes-of-high-dose-rate-intracavitary-brachytherapy-for-cervical-cancer-a-comparison-of-ir-192-versus-co-60-sources
#19
Thanatip Tantivatana, Kanisa Rongsriyam
OBJECTIVE: To determine and compare treatment outcomes between cobalt-60 (Co-60) and iridium-192 (Ir-192) high dose rate (HDR) brachytherapy in stage IB2-IIIB cervical cancer patients at Department of Radiology, Faculty of Medicine Vajira Hospital, Navamindrahiraj University. METHODS: A retrospective cohort study of patients diagnosed with cervical cancer and treated with radiotherapy at the Department of Radiation Oncology, Faculty of Medicine Vajira Hospital between 2004 and 2014...
September 2018: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/30048417/optimizing-the-approach-to-patients-with-pleural-effusion-and-radiologic-findings-suspect-for-cancer
#20
Bashar Alzghoul, Ayoub Innabi, Swathi Subramany, Bradley Boye, Kshitij Chatterjee, Vikas S Koppurapu, Thaddeus Bartter, Nikhil K Meena
BACKGROUND: When patients present with pleural effusion and structural abnormalities consistent with malignancy on imaging, the traditional approach has been to perform a thoracentesis and await the results before proceeding to more invasive diagnostic procedures. The objective of this study was to evaluate whether concurrent thoracentesis and tissue biopsy is superior to sequential sampling. METHODS: Retrospective chart review was performed for patients who had a pleural cytology from May 2014 until January 2017...
July 25, 2018: Journal of Bronchology & Interventional Pulmonology
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