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https://www.readbyqxmd.com/read/29757013/impact-of-a-behavioral-sleep-intervention-on-new-school-entrants-social-emotional-functioning-and-sleep-a-translational-randomized-trial
#1
Harriet Hiscock, Jon Quach, Kate Paton, Rebecca Peat, Lisa Gold, Sarah Arnup, Kah-Ling Sia, Elizabeth Nicolaou, Melissa Wake
OBJECTIVE/BACKGROUND: Determine the effects and costs of a brief behavioral sleep intervention, previously shown to improve child social-emotional functioning, sleep, and parent mental health, in a translational trial. PARTICIPANTS: Three hundred thirty-four school entrant children from 47 primary schools in Melbourne, Australia, with parent-reported moderate to severe behavioral sleep problems. METHODS: intervention group received sleep hygiene practices and standardized behavioral strategies delivered by trained school nurses in 2013 and 2014...
May 14, 2018: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/29066427/the-adoption-of-social-media-to-recruit-participants-for-the-cool-runnings-randomized-controlled-trial-in-australia
#2
Jacqueline D Burgess, Roy M Kimble, Kerrianne Watt, Cate M Cameron
BACKGROUND: Using social media to recruit specific populations for research studies is gaining popularity. Given that mothers of young children are the most active on social media, and young children are the most at risk of preventable burn injuries, social media was used to recruit mothers of young children to a burn prevention intervention. OBJECTIVE: The aim of this paper was to describe the social media recruitment methods used to enroll mothers of young children to the app-based burn prevention intervention Cool Runnings...
October 24, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28906423/empowering-parents-of-australian-infants-and-children-in-hospital-translation-cultural-adaptation-and-validation-of-the-empowerment-of-parents-in-the-intensive-care-30-aus-questionnaire
#3
MULTICENTER STUDY
Fenella J Gill, Sally Wilson, Laurene Aydon, Gavin D Leslie, Jos M Latour
OBJECTIVES: To translate, culturally adapt, and psychometrically test the EMpowerment of PArents in The Intensive Care-30 questionnaire in Australian pediatric critical care, neonatal, and pediatric ward settings. DESIGN: Cross-sectional, descriptive, multicenter study conducted in two phases; 1) translation and cultural adaptation and 2) validation of the EMpowerment of PArents in The Intensive Care-30 questionnaire. SETTINGS: Two Western Australian sites, the PICU and two pediatric wards of a children's hospital and the neonatal unit of a women's and newborn hospital...
November 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27974169/antibiotics-first-versus-surgery-for-appendicitis-a-us-pilot-randomized-controlled-trial-allowing-outpatient-antibiotic-management
#4
RANDOMIZED CONTROLLED TRIAL
David A Talan, Darin J Saltzman, William R Mower, Anusha Krishnadasan, Cecilia M Jude, Ricky Amii, Daniel A DeUgarte, James X Wu, Kavitha Pathmarajah, Ashkan Morim, Gregory J Moran
STUDY OBJECTIVE: Randomized trials suggest that nonoperative treatment of uncomplicated appendicitis with antibiotics-first is safe. No trial has evaluated outpatient treatment and no US randomized trial has been conducted, to our knowledge. This pilot study assessed feasibility of a multicenter US study comparing antibiotics-first, including outpatient management, with appendectomy. METHODS: Patients aged 5 years or older with uncomplicated appendicitis at 1 US hospital were randomized to appendectomy or intravenous ertapenem greater than or equal to 48 hours and oral cefdinir and metronidazole...
July 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/27678364/hepatocellular-carcinoma-screening-and-surveillance-in-2293-chronic-hepatitis-b-patients-in-an-endemic-area
#5
Teerapat Ungtrakul, Chulabhorn Mahidol, Pattra Chun-On, Charlie Laohapand, Surachate Siripongsakun, Akeanong Worakitsitisatorn, Sirachat Vidhayakorn, Wariya Boonchuay, Jiraporn Dechma, Gaidganok Sornsamdang, Kamonwan Soonklang, Tassanee Sriprayoon, Tawesak Tanwandee, Chirayu U Auewarakul
AIM: To determine the role of screening and surveillance of hepatocellular carcinoma (HCC) in treatment-naïve chronic hepatitis B (CHB) patients. METHODS: We recruited 2293 CHB patients (both males and females; aged 20-65 years). All patients were screened and underwent surveillance using abdominal ultrasonography (AUS) and serum alpha-fetoprotein (AFP) assay every 6 mo. The diagnosis, staging and treatment of HCC followed the American Association for the Study of Liver Diseases practice guidelines and the Barcelona Clinic Liver Cancer guidelines...
September 14, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27405984/potential-effectiveness-of-tolvaptan-to-improve-ascites-unresponsive-to-standard-diuretics-and-overall-survival-in-patients-with-decompensated-liver-cirrhosis
#6
Tomoharu Yamada, Takamasa Ohki, Yuki Hayata, Yuki Karasawa, Satoshi Kawamura, Daisaku Ito, Kentaro Kojima, Michiharu Seki, Nobuo Toda, Kazumi Tagawa
BACKGROUND AND OBJECTIVE: After tolvaptan was approved for the treatment of cirrhosis patients with ascites, only a few studies have reported its efficacy in the real clinical setting, and no studies have reported its contribution to overall survival. This study clarified the clinical outcomes of tolvaptan treatment in terms of improving ascites unresponsive to standard diuretics (AUS) and overall survival. METHODS: We retrospectively enrolled 80 decompensated cirrhosis patients with AUS who were administered tolvaptan from October 2012 to December 2014...
October 2016: Clinical Drug Investigation
https://www.readbyqxmd.com/read/26457584/impact-of-reclassifying-noninvasive-follicular-variant-of-papillary-thyroid-carcinoma-on-the-risk-of-malignancy-in-the-bethesda-system-for-reporting-thyroid-cytopathology
#7
William C Faquin, Lawrence Q Wong, Amir H Afrogheh, Syed Z Ali, Justin A Bishop, Massimo Bongiovanni, Marc P Pusztaszeri, Christopher J VandenBussche, Jolanta Gourmaud, Louis J Vaickus, Zubair W Baloch
BACKGROUND: Recent discussions have focused on redefining noninvasive follicular variant of papillary thyroid carcinoma (NI-FVPTC) as a neoplasm rather than a carcinoma. This study assesses the potential impact of such a reclassification on the implied risk of malignancy (ROM) for the diagnostic categories of The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). METHODS: The study consisted of consecutive fine-needle aspiration biopsy (FNAB) cases collected between January 1, 2013 and June 30, 2014 from 5 academic institutions...
March 2016: Cancer Cytopathology
https://www.readbyqxmd.com/read/26187350/magnetoencephalography-using-gradient-magnetic-field-topography-gmft-can-predict-successful-anterior-corpus-callosotomy-in-patients-with-drop-attacks
#8
Kota Kagawa, Koji Iida, Akira Hashizume, Masaya Katagiri, Shiro Baba, Kaoru Kurisu, Hiroshi Otsubo
OBJECTIVE: Gradient magnetic field topography (GMFT) with magnetoencephalography (MEG) has been developed to demonstrate magnetic-field gradients of epileptic spikes on a volume-rendered brain surface. We evaluated GMFT in patients with anterior 2/3 corpus callosotomy (ACC) for drop-attacks. METHODS: Eight patients (age; 11-37 years) underwent ACC. GMFT evaluated the predominant distributions (anterior/posterior) and the spreading patterns (unilateral/bilateral) of pre- and postoperative interictal MEG spikes corresponding to generalized spikes on EEG...
January 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/25879311/reclassification-of-cytologically-atypical-thyroid-nodules-based-on-radiologic-features-in-pediatric-patients
#9
Nicoleta C Arva, Sarah G Deitch
AIM: In children the percentage of "Atypia of undetermined significance/follicular lesion of undetermined significance" ("AUS/FLUS") cases is greater and the risk of malignancy is higher than expected. Our study aimed to determine if cytologically atypical nodules can be better characterized using imaging techniques for appropriate management of pediatric patients. METHODS: Thyroid fine needle aspiration (FNA) specimens were reclassified using the Bethesda System for Reporting Thyroid Cytopathology (BSRTC)...
July 2015: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/25869826/delayed-surgical-repair-of-posttraumatic-posterior-urethral-distraction-defects-in-children-and-adolescents-long-term-results
#10
COMPARATIVE STUDY
Miguel Podesta, Miguel Podesta
INTRODUCTION: Various surgical techniques have been proposed to treat pelvic fracture urethral distraction defects (PFUDDs) in children (Figure): primary alignment of the acute transected urethra, substitution procedures and delayed anastomosis urethroplasties (DAU) by perineal, elaborated perineal, transpubic or perineo-abdominal/partial transpubic access. However, long-term follow-up of surgical correction for PFUDDS with DAU is infrequently reported in the literature. PURPOSE: Long-term efficacy of DAU in children and adolescents with PFUDDs was evaluated...
April 2015: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/25740273/a-population-based-cost-description-study-of-oral-treatment-of-hospitalized-western-australian-children-aged-younger-than-15-years
#11
Alla Talal Alsharif, Estie Kruger, Marc Tennant
OBJECTIVES: We sought to analyze the economic cost of a decade of dental hospital admissions in Western Australian children under the age of 15 years and to identify socio-demographic characteristics associated with these costs. METHODS: This study analyzed the cost of 43,937 child patients under the age of 15 years hospitalized for an oral health-related condition, as determined by principal diagnosis International Classification of Diseases (ICD-10AM). The Australian Refine Diagnosis Related Group version 5...
2015: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/25728981/fine-needle-aspiration-of-thyroid-nodules-in-the-pediatric-population-a-12-year-cyto-histological-correlation-experience-at-north-shore-long-island-jewish-health-system
#12
Seema A Lale, Nora N Morgenstern, Sugrue Chiara, Patricia Wasserman
BACKGROUND: Diagnostic evaluation of thyroid nodules by FNA is used in the clinical management triage based on the knowledge of the rate of malignancy of each diagnostic category. The Bethesda System for Reporting Thyroid Cytopathology was published in 2007 by the National Cancer Institute (NCI). Using this classification, we studied our institution's experience in the pediatric population calculating the rate of malignancy for each diagnostic category, comparing our findings to our general patient population and that of the literature...
August 2015: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/25631593/australian-staphylococcus-aureus-sepsis-outcome-programme-annual-report-2013
#13
Geoffrey W Coombs, Graeme R Nimmo, Denise A Daly, Tam T Le, Julie C Pearson, Hui-Leen Tan, James O Robinson, Peter J Collignon, Mary-Louise McLaws, John D Turnidge
From 1 January to 31 December 2013, around Australia 26 institutions around Australia participated in the Australian Staphylococcal Sepsis Outcome Programme (ASSOP). The aim of ASSOP 2013 was to determine the proportion of Staphylococcus aureus bacteraemia (SAB) isolates in Australia that are antimicrobial resistant, (with particular emphasis on susceptibility to methicillin) and to characterise the molecular epidemiology of the isolates. Overall 19.1% of the 2,010 SAB episodes were methicillin resistant, which is significantly higher than that reported in most European countries...
December 2014: Communicable Diseases Intelligence Quarterly Report
https://www.readbyqxmd.com/read/24861815/characterization-of-g2p-4-rotavirus-strains-associated-with-increased-detection-in-australian-states-using-the-rotateq%C3%A2-vaccine-during-the-2010-2011-surveillance-period
#14
Celeste M Donato, Zheng Andrew Zhang, Nicole C Donker, Carl D Kirkwood
The introduction of rotavirus vaccines Rotarix® and RotaTeq® into the Australian National Immunisation Program in July 2007 has resulted in a dramatic decrease in the burden of rotavirus disease. G2P[4] strains became the dominant genotype Australia-wide during the 2010-2011 surveillance period and for the first time since vaccine introduction, a higher proportion were isolated in jurisdictions using RotaTeq® vaccine compared to locations using Rotarix®. Phylogenetic analysis of the VP7 gene of 32 G2P[4] strains identified six genetic clusters, these distinct clusters were also observed in the VP4 gene for a subset of 12 strains...
December 2014: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/24811685/the-importance-of-therapeutic-drug-monitoring-tdm-for-parenteral-busulfan-dosing-in-conditioning-regimen-for-hematopoietic-stem-cell-transplantation-hsct-in-children
#15
Hundie Tesfaye, Romana Branova, Eva Klapkova, Richard Prusa, Daniela Janeckova, Petr Riha, Petr Sedlacek, Petra Keslova, Josef Malis
BACKGROUND: Series of observations indicate PK/PD variability challenging the accuracy of the body-weight based busulfan (Bu) dosing schedule for (HSCT) conditioning therapy. The purpose of this communication is to describe the frequency of dose changes in initially body-weight-based fixed IV Bu dose and to emphasize the importance of TDM. MATERIAL AND METHODS: Sixty-two children (ages 2 months-18 years) were treated with IV busulfan doses based on body weight for myeloablation...
2014: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/24780429/genetic-characterization-of-a-novel-g3p-14-rotavirus-strain-causing-gastroenteritis-in-12-year-old-australian-child
#16
Celeste M Donato, Nicholas M Manuelpillai, Daniel Cowley, Susie Roczo-Farkas, Jim P Buttery, Nigel W Crawford, Carl D Kirkwood
A genotype G3P[14] rotavirus strain was identified in a 12year old child presenting to the Emergency Department of the Royal Children's Hospital, Melbourne, with gastroenteritis. G3P[14] strains have been previously identified in rabbits in Japan, China, the USA and Italy and a single lapine-like strain from a child in Belgium. Full genome sequence analysis of RVA/Human-wt/AUS/RCH272/2012/G3P[14] (RCH272) revealed that the strain contained the novel genome constellation G3-P[14]-I2-R3-C3-M3-A9-N2-T6-E2-H3. The genome was genetically divergent to previously characterized lapine viruses and the genes were distantly related to a range of human bovine-like strains and animal strains of bovine, bat and canine/feline characteristics...
July 2014: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/24595045/coeliac-patients-are-undiagnosed-at-routine-upper-endoscopy
#17
Kathryn Robson, Michelle Alizart, Jarad Martin, Robyn Nagel
BACKGROUND AND AIMS: Two out of three patients with Coeliac Disease (CD) in Australia are undiagnosed. This prospective clinical audit aimed to determine how many CD patients would be undiagnosed if duodenal biopsy had only been performed if the mucosa looked abnormal or the patient presented with typical CD symptoms. METHODS: All eligible patients presenting for upper gastrointestinal endoscopy (OGD) in a regional center from 2004-2009 underwent prospective analysis of presenting symptoms and duodenal biopsy...
2014: PloS One
https://www.readbyqxmd.com/read/24463639/reproductive-factors-and-the-risk-of-endometrial-cancer
#18
REVIEW
Aus Tariq Ali
Endometrial cancer is the most common malignancy of women in developed countries, and its incidence is 10 times higher than in developing countries. Endometrial cancer is most common in the sixth and the seventh decades of life; thus, postmenopausal women have a higher risk of developing the disease compared with premenopausal women. The increased incidence and prevalence of endometrial cancer can be explained by the increase in life expectancy, increased caloric intake, increased obesity rates, and other changes in lifestyle and reproductive factors...
March 2014: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/24460665/dental-hospitalization-trends-in-western-australian-children-under-the-age-of-15%C3%A2-years-a-decade-of-population-based-study
#19
Alla T Alsharif, Estie Kruger, Marc Tennant
BACKGROUND AND AIM: This study analyzed a decade of dental admission patterns in Western Australian children under the age of 15 years, examining associations with sociodemographic characteristics and with particular focus on dental decay and Indigenous children. METHODS: This retrospective study analyzed the data obtained for 43,937 child patients under the age of 15 years hospitalized for an oral-health-related condition, as determined by principal diagnosis (ICD-10AM)...
January 2015: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/24220269/rule-based-exposure-assessment-versus-case-by-case-expert-assessment-using-the-same-information-in-a-community-based-study
#20
COMPARATIVE STUDY
Susan Peters, Deborah C Glass, Elizabeth Milne, Lin Fritschi
BACKGROUND: Retrospective exposure assessment in community-based studies is largely reliant on questionnaire information. Expert assessment is often used to assess lifetime occupational exposures, but these assessments generally lack transparency and are very time-consuming. We explored the agreement between a rule-based assessment approach and case-by-case expert assessment of occupational exposures in a community-based study. METHODS: We used data from a case-control study of childhood acute lymphoblastic leukaemia in which parental occupational exposures were originally assigned by expert assessment...
March 2014: Occupational and Environmental Medicine
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