Samiksha Rele, Chanchal Kiran Thakur, Fatima Khan, Budhadev Baral, Vaishali Saini, Chandrabose Karthikeyan, N S Hari Narayana Moorthy, Hem Chandra Jha
Multi-walled Carbon Nanotubes (MWCNTs) are inert structures with high aspect ratios that are widely used as vehicles for targeted drug delivery in cancer and many other diseases. They are largely non-toxic in nature however, when cells are exposed to these nanotubes for prolonged durations or at high concentrations, they show certain adverse effects. These include cytotoxicity, inflammation, generation of oxidative stress, and genotoxicity among others. To combat such adverse effects, various moieties can be attached to the surface of these nanotubes...
March 25, 2024: Journal of Materials Science. Materials in Medicine