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Cervical intervertebral disc

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https://www.readbyqxmd.com/read/29903926/zonally-magnified-oblique-multislice-and-non-zonally-magnified-oblique-multislice-dwi-of-the-cervical-spinal-cord
#1
M Alizadeh, M M Poplawski, J Fisher, R J T Gorniak, A Dresner, F B Mohamed, A E Flanders
BACKGROUND AND PURPOSE: The zonally magnified oblique multislice EPI (ZOOM-EPI) diffusion-weighted sequence has been visually shown to provide superior MR diffusion image quality compared with the full-FOV single-shot EPI sequence (non-ZOOM-EPI) in the adult cervical spinal cord. The purpose of this study was to examine the diffusion tensor imaging indices in the normal human cervical spinal cord between ZOOMED and non-ZOOMED DTI acquisitions and determine whether DTI values are comparable between direct and indirect age-matched groups...
June 14, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29899321/quality-assessment-of-surgical-disc-samples-discriminates-human-annulus-fibrosus-and-nucleus-pulposus-on-tissue-and-molecular-level
#2
Ann-Kathrin Schubert, Jeske J Smink, Mirko Arp, Jochen Ringe, Aldemar A Hegewald, Michael Sittinger
A discrimination of the highly specialised annulus fibrosus (AF) and nucleus pulposus (NP) cells in the mature human intervertebral disc (IVD) is thus far still not possible in a reliable way. The aim of this study was to identify molecular markers that distinguish AF and NP cells in human disc tissue using microarray analysis as a screening tool. AF and NP samples were obtained from 28 cervical discs. First, all samples underwent quality sorting using two novel scoring systems for small-sized disc tissue samples including macroscopic, haptic and histological evaluation...
June 13, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29878713/comparative-study-between-m6-c-and-mobi-c-cervical-artificial-disc-replacement-biomechanical-outcomes-and-comparison-with-normative-data
#3
My Pham, Kevin Phan, Ian Teng, Ralph J Mobbs
OBJECTIVE: Cervical spondylosis affects a huge proportion of the middle-aged population. Degenerative changes can occur in multiple regions of the cervical spine typically affecting the joints, intervertebral discs and endplates. These changes lead to compression of adjacent nervous structures, which results in radiculopathic and myelopathic pain. Various treatment modalities are currently available with non-surgical approaches the initial go to if there is no symptomatic cord compression...
May 2018: Orthopaedic Surgery
https://www.readbyqxmd.com/read/29776411/a-study-of-the-factors-associated-with-cervical-spinal-disc-degeneration-with-a-focus-on-bone-metabolism-and-amino-acids-in-the-japanese-population-a-cross-sectional-study
#4
Kanichiro Wada, Toshihiro Tanaka, Gentaro Kumagai, Hitoshi Kudo, Toru Asari, Daisuke Chiba, Seiya Ota, Keita Kamei, On Takeda, Shigeyuki Nakaji, Yasuyuki Ishibashi
BACKGROUND: The physical and biochemical factors responsible for cervical disc degeneration, and resulting in various spinal disorders, remain unclear. This study aimed to evaluate the correlation between cervical spinal canal stenosis and degeneration of intervertebral discs, and to analyze the factors related to disc degeneration in the Japanese population. METHODS: Three hundred and forty-four Japanese general residents underwent investigations, including magnetic resonance imaging of the cervical spine, in our health check project...
May 17, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29772854/-observation-of-early-clinical-effect-of-percutaneous-transforaminal-endoscopic-technology-in-treating-cervical-spondylotic-radiculopathy
#5
Ying-Chun Zhang, Tai-Sheng Chen, Hua Zhu
OBJECTIVE: To explore the early clinical effect and safety of percutaneous transforaminal endoscopic technology for cervical spondylotic radiculopathy. METHODS: From August 2016 to September 2017, 14 patients with cervical spondylotic radiculopathy who responded poorly to non-surgical treatment for at least 6 weeks underwent percutaneous transforaminal endoscopic discectomy via posterior approach. There were 6 males and 8 females, aging from 32 to 68 years old with an average of (40...
April 25, 2018: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29762279/a-20-year-prospective-longitudinal-study-of-degeneration-of-the-cervical-spine-in-a-volunteer-cohort-assessed-using-mri-follow-up-of-a-cross-sectional-study
#6
Kenshi Daimon, Hirokazu Fujiwara, Yuji Nishiwaki, Eijiro Okada, Kenya Nojiri, Masahiko Watanabe, Hiroyuki Katoh, Kentaro Shimizu, Hiroko Ishihama, Nobuyuki Fujita, Takashi Tsuji, Masaya Nakamura, Morio Matsumoto, Kota Watanabe
BACKGROUND: Few studies have addressed in detail long-term degenerative changes in the cervical spine. In this study, we evaluated the progression of degenerative changes of the cervical spine that occurred over a 20-year period in an originally healthy cohort. We also sought to clarify the relationship between the progression of cervical degenerative changes and the development of clinical symptoms. METHODS: For this prospective follow-up investigation, we recruited 193 subjects from an original cohort of 497 participants who had undergone magnetic resonance imaging (MRI) of the cervical spine between 1993 and 1996...
May 16, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29751126/radiological-follow-up-after-implanting-cervical-disc-prosthesis-in-anterior-discectomy-a-systematic-review
#7
REVIEW
Xiaoyu Yang, Tessa Janssen, Mark P Arts, Wilco C Peul, Carmen L A Vleggeert-Lankamp
Objective The objective of this study was to review current literature on comparison of radiological outcome of cervical arthroplasty with fusion after anterior discectomy for radiculopathy. Methods A literature search was performed in PubMed, Embase, Web of Science, COCHRANE, CENTRAL and CINAHL using a sensitive search string combination. Studies were selected by predefined selection criteria (a.o. patients exclusively suffering from cervical radiculopathy) and risk of bias was assessed using a validated Cochrane Checklist adjusted for this purpose...
May 8, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29738991/digital-tracking-algorithm-reveals-the-influence-of-structural-irregularities-on-joint-movements-in-the-human-cervical-spine
#8
Christian Balkovec, Jim Veldhuis, John W Baird, G Wayne Brodland, Stuart M McGill
BACKGROUND: Disc height loss and osteophytes change the local mechanical environment in the spine; while previous research has examined kinematic dysfunction under degenerative change, none has looked at the influence of disc height loss and osteophytes throughout movement. METHODS: Twenty patients with pain related to the head, neck or shoulders were imaged via videofluoroscopy as they underwent sagittal-plane flexion and extension. A clinician graded disc height loss and osteophytes as "severe/moderate", "mild", or "none"...
April 26, 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/29713417/clinical-relationship-of-degenerative-changes-between-the-cervical-and-lumbar-spine
#9
Yuichiro Morishita, Zorica Buser, Anthony D'Oro, Keiichiro Shiba, Jeffrey C Wang
Study Design: Retrospective, observational, case series. Purpose: To elucidate the prevalence of degenerative changes in the cervical and lumbar spine and estimate the degenerative changes in the cervical spine based on the degeneration of lumbar disc through a retrospective review of magnetic resonance (MR) images. Overview of Literature: Over 50% of middle-aged adults show evidence of spinal degeneration. However, the relationship between degenerative changes in the cervical and lumbar spine has yet to be elucidated...
April 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29713411/percutaneous-endoscopic-cervical-discectomy-surgical-approaches-and-postoperative-imaging-changes
#10
Shu Nakamura, Mitsuto Taguchi
Study Design: Retrospective clinical study. Purpose: This study investigated the relationship between surgical approaches and surgical outcomes in patients undergoing percutaneous endoscopic cervical discectomy (PECD), including the reduction in intervertebral disc height and the incidence of Modic changes. Overview of Literature: The anterior approach involves partial invasion of the intervertebral disc, with a reported reduction in intervertebral disc height after PECD...
April 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29709826/preliminary-female-cervical-spine-injury-risk-curves-from-pmhs-tests
#11
Narayan Yoganandan, Sajal Chirvi, Frank A Pintar, Jamie L Baisden, Anjishnu Banerjee
The human cervical spine sustains compressive loading in automotive events and military operational activities, and the contact and noncontact loading are the two primary impact modes. Biomechanical and anatomical studies have shown differences between male and female cervical spines. Studies have been conducted to determine the human tolerance in terms of forces from postmortem human subject (PMHS) specimens from male and female spines; however, parametric risk curves specific to female spines are not available from contact loading to the head-neck complex under the axial mode...
July 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29675672/low-virulence-bacterial-infections-in-cervical-intervertebral-discs-a-prospective-case-series
#12
Yilei Chen, Xianjun Wang, Xuyang Zhang, Hong Ren, Bao Huang, Jian Chen, Junhui Liu, Zhi Shan, Zhihai Zhu, Fengdong Zhao
STUDY DESIGN: A prospective cross-sectional case series study. OBJECTIVE: To investigate the prevalence of low virulence disc infection and its associations with characteristics of patients or discs in the cervical spine. BACKGROUND: Low virulence bacterial infections could be a possible cause of intervertebral disc degeneration and/or back pain. Controversies are continuing over whether these bacteria, predominantly Propionibacterium acnes (P...
April 19, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29670903/apparent-diffusion-coefficient-of-diffusion-weighted-imaging-in-evaluation-of-cervical-intervertebral-disc-degeneration-an-observational-study-with-3-0-t-magnetic-resonance-imaging
#13
Pinjie Chen, Chunlei Wu, Minghua Huang, Guangjian Jin, Qinglei Shi, Zhihua Han, Chun Chen
Aims: To investigate the correlation between the apparent diffusion coefficient (ADC) value and cervical intervertebral disc degeneration in adult symptomatic patients. Methods: A total of 52 symptomatic and 40 healthy volunteers were included. DWI and routine MRI examinations were performed to their cervical spines. The cervical discs (from C2-C3 to C6-C7) were graded according to the Pfirrmann grading system, and ADC values of the nucleus pulposus (NP) were measured...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29669576/modic-changes-in-the-cervical-endplate-of-patients-suffering-from-cervical-spondylotic-myelopathy
#14
Pan Qiao, Tian-Tong Xu, Wen Zhang, Rong Tian
BACKGROUND: The distribution and related factors of Modic changes (MC) in the lumbar spine has been evaluated. In the present study, the MC in the cervical endplate of patients with cervical spondylotic myelopathy (CSM) was investigated. METHODS: A total of 6422 cervical endplates of 539 patients suffered from CSM (259 males and 280 females) with mean age of 46 ± 5.2 years. All patients underwent MRI scans and X-ray for evaluating the distribution of MC. The clinical information were recorded...
April 18, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29658148/biochemical-and-biomechanical-characterisation-of-equine-cervical-facet-joint-cartilage
#15
S A O'Leary, J L White, J C Hu, K A Athanasiou
BACKGROUND: The equine cervical facet joint is a site of significant pathology. Located bilaterally on the dorsal spine, these diarthrodial joints work in conjunction with the intervertebral disc to facilitate appropriate spinal motion. Despite the high prevalence of pathology in this joint, the facet joint is understudied and thus lacking in viable treatment options. OBJECTIVE: The goal of this study was to characterise equine facet joint cartilage and provide a comprehensive database describing the morphological, histological, biochemical and biomechanical properties of this tissue...
April 15, 2018: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29643538/-anterior-cervical-discectomy-and-fusion-to-treat-cervical-spondylosis-with-sympathetic-symptoms
#16
H Liu, L Yue, S L Chen, B Hu, C D Li, X D Yi, H Li, H L Lu, Y Wang, Z R Yu, H L Sun, S J Wang, Y Zhao, L T Qi, R Wang
OBJECTIVE: To investigate the clinical effectiveness of polytheretherketone (PEEK) cages assisted anterior cervical discetomy and fusion (ACDF) to treat cervical spondylosis with sympathetic symptoms. METHODS: Retrospective analysis was undertaken for 39 patients who were diagnosed as cervical spondylosis with sympathetic symptoms and underwent ACDF with PEEK cages. Radiographs obtained before surgery, after surgery, and at the final follow-up were assessed for quality of fusion...
April 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29621987/distribution-of-ossified-spinal-lesions-in-patients-with-severe-ossification-of-the-posterior-longitudinal-ligament-and-prediction-of-ossification-at-each-segment-based-on-the-cervical-op-index-classification-a-multicenter-study-josl-ct-study
#17
Takashi Hirai, Toshitaka Yoshii, Narihito Nagoshi, Kazuhiro Takeuchi, Kanji Mori, Shuta Ushio, Akio Iwanami, Tsuyoshi Yamada, Shoji Seki, Takashi Tsuji, Kanehiro Fujiyoshi, Mitsuru Furukawa, Soraya Nishimura, Kanichiro Wada, Takeo Furuya, Yukihiro Matsuyama, Tomohiko Hasegawa, Katsushi Takeshita, Atsushi Kimura, Masahiko Abematsu, Hirotaka Haro, Tetsuro Ohba, Masahiko Watanabe, Hiroyuki Katoh, Kei Watanabe, Hiroshi Ozawa, Haruo Kanno, Shiro Imagama, Kei Ando, Shunsuke Fujibayashi, Masao Koda, Masashi Yamazaki, Morio Matsumoto, Masaya Nakamura, Atsushi Okawa, Yoshiharu Kawaguchi
BACKGROUND: In patients with ossification of the posterior longitudinal ligament (OPLL) in the cervical spine, it is well known that the thoracic ossified lesions often coexist with the cervical lesions and can cause severe myelopathy. However, the prevalence of OPLL at each level of the thoracic and lumbar spinal segments is unknown. The aims of this study were to investigate how often OPLL occurs at each level in the thoracolumbar spine in patients with a radiological diagnosis of cervical OPLL and to identify the spinal levels most likely to develop ossification...
April 5, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29615017/clinical-and-radiographic-outcome-of-dynamic-cervical-implant-dci-arthroplasty-for-degenerative-cervical-disc-disease-a-minimal-five-year-follow-up
#18
Lin-Nan Wang, Bo-Wen Hu, Lei Wang, Yue-Ming Song, Xi Yang, Li-Min Liu, Hao Liu
BACKGROUND: To evaluate the mid- to long-term clinical and radiographic outcomes of anterior cervical discectomy and dynamic cervical implant (DCI) arthroplasty for degenerative cervical disc disease. METHODS: From April 2010 to October 2010, 38 patients with single- or double-level cervical disc herniation underwent anterior cervical discectomy and DCI arthroplasty. The clinical results and radiographic outcomes of these 38 patients (42 levels) were retrospectively evaluated...
April 4, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29599656/degenerative-cervical-myelopathy-a-clinical-review
#19
REVIEW
Justin Gibson, Aria Nouri, Bryan Krueger, Nikita Lakomkin, Rani Nasser, David Gimbel, Joseph Cheng
Degenerative Cervical Myelopathy (DCM) is the most common form of spinal cord impairment in adults and results in disability and reduced quality of life. DCM can present with a wide set of clinical and imaging findings, including: 1) pain and reduced range of motion of the neck, and motor and sensory deficits on clinical exam, and 2) cord compression due to static and dynamic injury mechanisms resulting from degenerative changes of the bone, ligaments, and intervertebral discs on MRI. The incidence and prevalence of DCM has been estimated at a minimum of 4...
March 2018: Yale Journal of Biology and Medicine
https://www.readbyqxmd.com/read/29584503/influence-of-morphological-variations-on-cervical-spine-segmental-responses-from-inertial-loading
#20
Jobin D John, Narayan Yoganandan, Mike W J Arun, G Saravana Kumar
OBJECTIVES: The objective of this study was to investigate the influence of morphological variations in osteoligamentous lower cervical spinal segment responses under postero-anterior inertial loading. METHODS: A parametric finite element model of the C5-C6 spinal segment was used to generate models. Variations in the vertebral body and facet depth (anteroposterior), posterior process length, intervertebral disc height, facet articular process height and slope, segment orientation ranging from lordotic to straight, and segment size were parameterized...
February 28, 2018: Traffic Injury Prevention
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