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Cervical intervertebral disc

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https://www.readbyqxmd.com/read/28498027/asthma-and-early-herniated-intervertebral-disc-disease
#1
Cheng-Di Chiu, Hsuan-Ju Chen, Hean-Pat Saw, Nai-Wei Yao, Hung-Rong Yen, Chia-Hung Kao
BACKGROUND: The etiology of herniated intervertebral disc (HIVD) disease in children and adolescents is multifactorial and not merely related to disc degeneration. Therefore, in the present study, we investigated the relationship between young asthma patients and the risk of early HIVD disease in a population under 30 years of age. MATERIALS AND METHODS: Data from the National Health Insurance Research Database (NHIRD) of Taiwan were used to conduct a retrospective longitudinal cohort study...
May 12, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28430387/age-related-reduction-in-the-expression-of-foxo-transcription-factors-and-correlations-with-intervertebral-disc-degeneration
#2
Oscar Alvarez-Garcia, Tokio Matsuzaki, Merissa Olmer, Koichi Masuda, Martin K Lotz
Aging is a main risk factor for intervertebral disc (IVD) degeneration, the main cause of low back pain. FOXO transcription factors are important regulators of tissue homeostasis and longevity. Here, we determined the expression pattern of FOXO in healthy and degenerated human IVD and the associations with IVD degeneration during mouse aging. FOXO expression was assessed by immunohistochemistry in normal and degenerated human IVD samples and in cervical and lumbar IVD from 6-, 12-, 24-, and 36-month-old C57BL/6J mice...
April 21, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28408260/evaluation-of-bioabsorbable-multiamino-acid-copolymer-nano-hydroxyapatite-calcium-sulphate-cage-in-a-goat-spine-model
#3
Chunpeng Ren, Yueming Song, Youdi Xue, Xi Yang, Chunguang Zhou
BACKGROUND: Recently, polylactide is the most popular material used to made bioabsorbable cages, but too fast degradation and osteolysis around the cage have been reported in the literature. This study evaluated the fusion effect, biomechanical stability and histological characteristics of a novel bioabsorbable multi-amino acid copolymer/nano-hydroxyapatite/calcium sulphate (MAACP/n-HA/CS) interbody cage in a goat model of anterior cervical discectomy and fusion (ACDF). METHODS: A total of 24 goats underwent C3/C4 discectomy and fusion with three groups of intervertebral implants: MAACP/n-HA/CS cage group (n = 8), titanium cage group (n = 8) and autologous tricortical iliac crest bone group (n = 8)...
April 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28402031/evaluation-of-osseous-associated-cervical-spondylomyelopathy-in-dogs-using-kinematic-magnetic-resonance-imaging
#4
Michele Provencher, Amy Habing, Sarah A Moore, Laurie Cook, Gary Phillips, Ronaldo C da Costa
Osseous-associated cervical spondylomyelopathy in dogs is characterized by both static and dynamic spinal cord compression; however, standard MRI methods only assess static compression. In humans with cervical spondylotic myelopathy, kinematic MRI is commonly used to diagnose dynamic spinal cord compressions. The purpose of this prospective, analytical study was to evaluate kinematic MRI as a method for characterizing the dynamic component of osseous-associated cervical spondylomyelopathy in dogs. We hypothesized that kinematic MRI would allow visualization of spinal cord compressions that were not identified with standard imaging...
April 12, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28378073/kinematics-of-cervical-segments-c5-c6-in-axial-rotation-before-and-after-total-disc-arthroplasty
#5
Martin Michael Wachowski, Jan Weiland, Markus Wagner, Riccardo Gezzi, Dietmar Kubein-Meesenburg, Hans Nägerl
PURPOSE: The kinematical properties of C5/C6 segments in axial rotation are evaluated before and after total disc arthroplasty (TDA) with PRESTIGE(®)-and BRYAN(®) Cervical Disc (Medtronic) under flexion/extension as parameters and compared with those of C3/C4. METHODS: Eight human segments were stimulated by triangularly varying, axially directed torque (T z(t)) under compressing static axial preloads. Using a 6D-measuring device with high resolution, the response of segmental motion was characterized by the instantaneous helical axis (IHA)...
April 4, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28377861/outpatient-anterior-cervical-discectomy-and-fusion-an-analysis-of-readmissions-from-the-new-jersey-state-ambulatory-services-database
#6
Shearwood McClelland, Peter G Passias, Thomas J Errico, R Shay Bess, Themistocles S Protopsaltis
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) performed as an outpatient has become increasingly common for treating cervical spine pathology. Few reports have attempted to assess readmissions following outpatient ACDF. This study was performed to address this issue using population-based databases. METHODS: The State Ambulatory Services Database (SASD) for New Jersey (NJ) from 2003-2012 was used for analysis. Patients receiving ACDF (defined as anterior cervical fusion (ICD-0 code=81...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28377542/myelopathy-associated-with-age-related-cervical-disc-herniation-a-retrospective-review-of-magnetic-resonance-images
#7
Nosaiba Tawfik Al-Ryalat, Saif Aldeen Saleh, Walid Sulaiman Mahafza, Osama Ahmad Samara, Abdee Tawfiq Ryalat, Azmy Mohammad Al-Hadidy
BACKGROUND: Cervical intervertebral disc herniation can lead to myelopathy. Aging is an established variable related to spondylotic myelopathy. Studying this association will help in controlling the increase in spondylotic myelopathy with age. OBJECTIVES: To study the association between cervical disc level, its direction, and the frequency of my-elopathy with age, and to assess the epidemiology of age-related cervical disc herniation and myelopathy. DESIGN: Retrospective review of magnetic resonance (MR) images...
March 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/28368985/prediction-of-cervical-spinal-joint-loading-and-secondary-motion-using-a-musculoskeletal-multibody-dynamics-model-via-force-dependent-kinematics-approach
#8
Hao Diao, Hua Xin, Jun Dong, Xijing He, Dichen Li, Zhongmin Jin
STUDY DESIGN: A cervical spine biomechanical investigation using multibody dynamics. OBJECTIVE: To develop a comprehensive cervical spine multibody dynamics model incorporated with the force-dependent kinematics (FDK) approach, and to study the influence of soft tissue deformation on the joint loading prediction. SUMMARY OF BACKGROUND DATA: Musculoskeletal multibody dynamics models have been widely used to analyze joint loading. Current cervical spine musculoskeletal models, however, neglect the joint internal motion caused by soft tissue deformation...
March 31, 2017: Spine
https://www.readbyqxmd.com/read/28346006/magnetic-resonance-imaging-susceptibility-artifacts-in-the-cervical-vertebrae-and-spinal-cord-related-to-monocortical-screw-polymethylmethacrylate-implants-in-canine-cadavers
#9
Brian G Jones, Geoffrey T Fosgate, Eric M Green, Amy M Habing, Bianca F Hettlich
OBJECTIVE To characterize and compare MRI susceptibility artifacts related to titanium and stainless steel monocortical screws in the cervical vertebrae and spinal cord of canine cadavers. SAMPLE 12 canine cadavers. PROCEDURES Cervical vertebrae (C4 and C5) were surgically stabilized with titanium or stainless steel monocortical screws and polymethylmethacrylate. Routine T1-weighted, T2-weighted, and short tau inversion recovery sequences were performed at 3.0 T. Magnetic susceptibility artifacts in 20 regions of interest (ROIs) across 4 contiguous vertebrae (C3 through C6) were scored by use of an established scoring system...
April 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28340590/comparison-of-angle-shape-and-position-of-articular-processes-in-dobermans-and-great-danes-with-and-without-cervical-spondylomyelopathy
#10
Marília de Albuquerque Bonelli, Ronaldo Casimiro da Costa, Paula Martin-Vaquero, Carolina Gonçalves Dias Lima
BACKGROUND: Cervical spondylomyelopathy (CSM), also known as wobbler syndrome, affects mainly large and giant-breed dogs, causing compression of the cervical spinal cord and/or nerve roots. Structural and dynamic components seem to play a role in the development of CSM; however, pathogenesis is not yet fully understood. Physiologic and pathologic movements of the cervical spine depend on the morphology and morphometry of articular processes, as well as on intervertebral discs and vertebral column ligaments...
March 24, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28334358/ranges-of-cervical-intervertebral-disc-deformation-during-an-in-vivo-dynamic-flexion-extension-of-the-neck
#11
Yan Yu, Haiqing Mao, Jing-Sheng Li, Tsung-Yuan Tsai, Liming Cheng, Kirkham B Wood, Guoan Li, Thomas D Cha
While abnormal loading is widely believed to cause cervical spine disc diseases, in vivo cervical disc deformation during dynamic neck motion has not been well delineated. This study investigated the range of cervical disc deformation during an in vivo functional flexion-extension of the neck. Ten asymptomatic human subjects were tested using a combined dual fluoroscopic imaging system (DFIS) and magnetic resonance imaging (MRI)-based three-dimensional (3D) modeling technique. Overall disc deformation was determined using the changes of the space geometry between upper and lower endplates of each intervertebral segment (C3/4, C4/5, C5/6, and C6/7)...
June 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28326638/intervertebral-disc-calcification-with-ossification-of-the-posterior-longitudinal-ligament
#12
Kaori Mizukawa, Takako Kobayashi, Nobuharu Yamada, Takahisa Hirota
A 6-year-old girl presented to hospital with a 4 day history of increasing neck pain. White blood cell count was normal with slightly raised C-reactive protein. The patient had a limited range of neck movement, and experienced enhanced pain with neck extension. X-ray and cervical computed tomography (CT) confirmed the diagnosis of cervical intervertebral disc calcification (IDC) and IDC with ossification of the posterior longitudinal ligament (OPLL), respectively. The symptoms improved after approximately 1 week following rest and oral acetaminophen...
March 21, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28321567/adjacent-segment-pathology-natural-history-or-effect-of-anterior-cervical-discectomy-and-fusion-a-10-year-follow-up-radiological-multicenter-study-using-an-evaluation-scale-of-the-ageing-spine
#13
Alessandro Pesce, Venceslao Wierzbicki, Emanuele Piccione, Alessandro Frati, Antonino Raco, Riccardo Caruso
PURPOSE: Aim of this study is to compare late degenerative MRI changes in a subset of patients operated on with ACDF to a second subset of patients presenting indication to ACDF but never operated on. METHODS: Patients from both subgroups received surgical indication according to the same criteria. Both subgroups underwent a cervical spine MRI in 2004-2005 and 10 years later in 2015. These MRI scans were retrospectively evaluated with a cervical spine ageing scale...
March 20, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28294643/a-videofluoroscopy-based-tracking-algorithm-for-quantifying-the-time-course-of-human-intervertebral-displacements
#14
Christian Balkovec, Jim H Veldhuis, John W Baird, G Wayne Brodland, Stuart M McGill
The motions of individual intervertebral joints can affect spine motion, injury risk, deterioration, pain, treatment strategies, and clinical outcomes. Since standard kinematic methods do not provide precise time-course details about individual vertebrae and intervertebral motions, information that could be useful for scientific advancement and clinical assessment, we developed an iterative template matching algorithm to obtain this data from videofluoroscopy images. To assess the bias of our approach, vertebrae in an intact porcine spine were tracked and compared to the motions of high-contrast markers...
May 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28261429/radiological-parameters-of-undegenerated-cervical-vertebral-segments-in-a-korean-population
#15
Sung Hoon Choi, HeeSang Lee, Jae Hwan Cho, Jin Il Jung, Dong-Ho Lee
BACKGROUND: Several scoring systems for cervical disc and facet joint degeneration, using radiography or computed tomography, have been developed and tested for reliability. However, definitions of disc height and facet joint space narrowing vary. To our knowledge, no study has reported quantitative data for normal radiologic values of the cervical spine in the Korean population. The purpose of this study is to determine normal cervical disc height, disc height ratio, and facet joint space values, and investigate the correlation between demographic data and these values...
March 2017: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/28254673/cervical-lordosis-the-effect-of-age-and-gender
#16
Ella Been, Sara Shefi, Michalle Soudack
BACKGROUND CONTEXT: The cervical lordosis is of great importance to posture and function. Neck pain and disability is often associated with cervical lordosis malalignment. Surgical procedures involving cervical lordosis stabilization or restoration must take into account age and gender differences in cervical lordosis architecture to avoid further complications. PURPOSE: Therefore, the purpose of the present study was to evaluate differences in the cervical lordosis between males and females from childhood to adulthood...
February 27, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28246009/clinical-and-radiographic-features-of-hybrid-surgery-for-the-treatment-of-skip-level-cervical-degenerative-disc-disease-a-minimum-24-month-follow-up
#17
Ting-Kui Wu, Bei-Yu Wang, Ding Cheng, Xin Rong, Ji-Gang Lou, Ying Hong, Hao Liu
We describe the radiographic changes of IS and investigate the safety and feasibility of hybrid surgery (HS) coupling cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF) for the treatment of skip-level cervical degenerative disc disease (CDDD). Twenty-seven patients who received HS were retrospectively reviewed. Clinical evaluation based on the Japanese Orthopedic Association (JOA) and Neck Disability Index (NDI) and Visual Analog Scale (VAS) scores. Radiographic parameters included cervical alignment (CA), functional spine unite (FSU) angle of intermediated segment (IS), range of motion (ROM) and intervertebral disc height (IDH)...
February 25, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28241721/-radiographic-assessment-of-vertebral-artery-injury-in-anterior-cervical-surgery-in-healthy-adults
#18
H L Wang, L Jiang, F Z Lyu, X S Ma, X L Xia, J Y Jiang
Objectives: To study the relationship between the anatomical parameters of transverse foramen and intervertebral discs in the cross-section of the cervical spine in healthy adults, and to evaluate the risk of vertebral artery injury in the anterior cervical spine surgery. Methods: There were 24 healthy adults(12 male, 12 female) underwent neck CT angiography with clear vertebral artery and the adjacent structure imaging from June to December 2014 in Huashan Hospital, Fudan University. The anatomical parameters of vertebral artery V2 segment with lower cervical vertebrae and intervertebral discs were measured by cross-sectional images of C(3-6)...
March 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28208824/associations-between-obesity-and-spinal-diseases-a-medical-expenditure-panel-study-analysis
#19
Binwu Sheng, Chaoling Feng, Donglan Zhang, Hugh Spitler, Lu Shi
Background: The link between body weight status and spinal diseases has been suggested by a number of cross-sectional and cohort studies with a limited range of patient populations. No population-representative samples have been used to examine the link between obesity and spinal diseases. The present study is based on a nationally representative sample drawn from the Medical Expenditure Panel Survey. Methods: Using the cross-sectional sample of the 2014 Medical Expenditure Panel Study, we built four weighted logistic regression analyses of the associations between body weight status and the following four spinal diseases: low back pain, spondylosis, other cervical disorders and intervertebral disc disorder (IDD)...
February 13, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28171773/cervical-traction-therapy-with-and-without-neck-support-a-finite-element-analysis
#20
Kuan Wang, Huihao Wang, Zhen Deng, Zhengyan Li, Hongsheng Zhan, Wenxin Niu
BACKGROUND: Cervical traction is commonly used for treating neck pain. However, few studies have investigated the biomechanical impact such traction has on soft tissues. OBJECTIVES: To analyze the biomechanics of cervical traction therapy in a supine position with and without neck support (NS and non-NS). METHODS: A finite element model of the cervical spine was constructed to investigate the mechanism behind cervical traction therapy. An axial traction force of 100-N was loaded on the upper surface of C0 to simulate traction weight...
April 2017: Musculoskeletal Science & Practice
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