Ichiei Narita, Terumasa Hayashi, Shoichi Maruyama, Takao Masaki, Masaomi Nangaku, Tomoya Nishino, Hiroshi Sato, Tadashi Sofue, Takashi Wada, Enyu Imai, Manabu Iwasaki, Kyoichi Mizuno, Hiroki Hase, Masahiro Kamouchi, Hiroyasu Yamamoto, Tatsuo Kagimura, Kenichiro Tanabe, Hideki Kato, Takehiko Wada, Tomoko Usui, Tadao Akizawa, Hideki Hirakata, Yoshiharu Tsubakihara
Among non-dialysis-dependent chronic kidney disease (ND-CKD) patients, a low hematopoietic response to erythropoiesis-stimulating agents (ESAs) is a predictor for poor renal and cardiovascular outcome. To assess the method for evaluating hyporesponsiveness to ESA in patients with ND-CKD, a multicenter, prospective, observational study of 1,980 adult patients with ND-CKD with renal anemia was conducted. Darbepoetin alfa (DA) and iron supplement administrations were provided according to the recommendation of the attached document and the guidelines of JSDT (Japanese Society of Dialysis and Transplantation)...
2022: PloS One