keyword
https://read.qxmd.com/read/38629048/mechanoreceptor-sensory-feedback-is-impaired-by-pressure-induced-cutaneous-ischemia-on-the-human-foot-sole-and-can-predict-cutaneous-microvascular-reactivity
#1
JOURNAL ARTICLE
Erika E Howe, Michael Apollinaro, Leah R Bent
INTRODUCTION: The foot sole endures high magnitudes of pressure for sustained periods which results in transient but habitual cutaneous ischemia. Upon unloading, microvascular reactivity in cutaneous capillaries generates an influx of blood flow (PORH: post-occlusive reactive hyperemia). Whether pressure induced cutaneous ischemia from loading the foot sole impacts mechanoreceptor sensitivity remains unknown. METHODS: Pressure induced ischemia was attained using a custom-built-loading device that applied load to the whole right foot sole at 2 magnitudes (15 or 50% body weight), for 2 durations (2 or 10 minutes) in thirteen seated participants...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38628843/clinical-outcomes-and-immunological-response-to-sars-cov-2-infection-among-people-living-with-hiv
#2
REVIEW
Esimebia Adjovi Amegashie, Prince Asamoah, Lawrencia Emefa Ami Ativi, Mildred Adusei-Poku, Evelyn Yayra Bonney, Emmanuel Ayitey Tagoe, Elijah Paintsil, Kwasi Torpey, Osbourne Quaye
People living with HIV (PLWH) usually suffer from co-infections and co-morbidities including respiratory tract infections. SARS-CoV-2 has been reported to cause respiratory infections. There are uncertainties in the disease severity and immunological response among PLWH who are co-infected with COVID-19. This review outlines the current knowledge on the clinical outcomes and immunological response to SARS-CoV-2 among PLWH. Literature was searched in Google scholar, Scopus, PubMed, and Science Direct conforming with the Preferred Reporting Items for Systematic reviews and Meta-analyses (PRISMA) guidelines from studies published from January 2020 to June 2023...
2024: Experimental Biology and Medicine
https://read.qxmd.com/read/38627890/nanomechanical-and-microstructural-characterization-of-biocompatible-ti-3-au-thin-films-grown-on-glass-and-ti-6-al-4-v-substrates
#3
JOURNAL ARTICLE
Cecil Cherian Lukose, Ioannis Anestopoulos, Mihalis I Panayiotidis, Martin Birkett
Ti-Au intermetallic-based material systems are being extensively studied as next-generation thin film coatings to extend the lifetime of implant devices. These coatings are being developed for application to the articulating surfaces of total joint implants and, therefore, must have excellent biocompatibility combined with superior mechanical hardness and wear resistance. However, these key characteristics of Ti-Au coatings are heavily dependent upon factors such as the surface properties and temperature of the underlying substrate during thin film deposition...
April 16, 2024: ACS Biomaterials Science & Engineering
https://read.qxmd.com/read/38626669/equivalent-weight-application-of-the-assessment-method-on-real-task-conducted-by-railway-workers-wearing-a-back-support-exoskeleton
#4
JOURNAL ARTICLE
Christian Di Natali, Giorgio Buratti, Luca Dellera, Darwin Caldwell
Commonly used risk indexes, such as the NIOSH Lifting Index, do not capture the effect of exoskeletons. This makes it difficult for Health and Safety professionals to rigorously assess the benefit of such devices. The community requires a simple method to assess the effectiveness of back-support exoskeleton's (BSE) in possibly reducing ergonomic risk. The method introduced in this work is termed "Equivalent Weight" (EqW) and it proposes an interpretation of the effect built on the benefit delivered through reduced activation of the erector spinae (ES)...
April 15, 2024: Applied Ergonomics
https://read.qxmd.com/read/38626084/nursing-staff-presenteeism-scale-development-and-psychometric-test
#5
JOURNAL ARTICLE
Shiao-Pei Hung, Jin-Lain Ming, Mei-Yu Chang, Chi Wang, Chii Jeng
BACKGROUND AND OBJECTIVES: Nurses tend to exhibit higher rates of presenteeism compared to other professions. Presenteeism can cause the work performance of nurses to suffer, jeopardizing their own and their patients' safety and leading to decreased quality of care and increased risks of errors. However, there is a lack of a validated assessment tool for presenteeism in Taiwan. Thus, the purpose of this study was to develop a Nursing Staff Presenteeism Scale (NSPS). METHODS: To develop questionnaire items, participants from three medical centers in Taiwan were recruited...
2024: PloS One
https://read.qxmd.com/read/38623773/field-method-for-preservation-of-total-mercury-in-waters-including-those-associated-with-artisanal-scale-gold-mining
#6
JOURNAL ARTICLE
David C P King, Michael J Watts, Elliott M Hamilton, Robert J G Mortimer, Mike Coffey, Odipo Osano, Maureene Auma Ondayo, Marcello Di Bonito
Analysis of mercury (Hg) in natural water samples has routinely been impractical in many environments, for example, artisanal and small-scale gold mines (ASGM), where difficult conditions make monitoring of harmful elements and chemicals used in the processes highly challenging. Current sampling methods require the use of hazardous or expensive materials, and so difficulties in sample collection and transport are elevated. To solve this problem, a solid-phase extraction-based method was developed for the sampling and preservation of dissolved Hg in natural water samples, particularly those found around ASGM sites...
April 16, 2024: Analytical Methods: Advancing Methods and Applications
https://read.qxmd.com/read/38617367/non-invasive-neuromodulation-of-cerebello-hippocampal-volume-behavior-relationships
#7
Thamires N C Magalhães, Ted Maldonado, T Bryan Jackson, Tracey H Hicks, Ivan A Herrejon, Thiago J R Rezende, Abigail C Symm, Jessica A Bernard
The study here explores the link between transcranial direct current stimulation (tDCS) and brain-behavior relationships. We propose that tDCS may indirectly influence the complex relationships between brain volume and behavior. We focused on the dynamics between the hippocampus (HPC) and cerebellum (CB) in cognitive processes, a relationship with significant implications for understanding memory and motor skills. Seventy-four young adults (mean age: 22±0.42 years, mean education: 14.7±0.25 years) were randomly assigned to receive either anodal, cathodal, or sham stimulation...
April 1, 2024: bioRxiv
https://read.qxmd.com/read/38615356/in-field-use-of-i-ved-electrical-impedance-sensor-for-assessing-post-dive-decompression-stress-in-humans
#8
JOURNAL ARTICLE
Sotiris P Evgenidis, Konstantinos Zacharias, Virginie Papadopoulou, Sigrid Theunissen, Costantino Balestra, Thodoris D Karapantsios
PURPOSE: Ultrasound imaging is commonly used in decompression research to assess venous gas emboli (VGE) post-dive, with higher loads associated with increased decompression sickness risk. This work examines, for the first time in humans, the performance of a novel electrical impedance spectroscopy technology (I-VED), on possible detection of post-dive bubbles presence and arterial endothelial dysfunction that may be used as markers of decompression stress. METHODS: I-VED signals were recorded in scuba divers who performed standardized pool dives before and at set time points after their dives at 35-minute intervals for about two hours...
2024: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://read.qxmd.com/read/38613461/age-and-gender-differences-in-the-perception-and-use-of-soft-vs-rigid-exoskeletons-for-manual-material-handling
#9
JOURNAL ARTICLE
Rahul Narasimhan Raghuraman, Dechristian França Barbieri, Jessica Aviles, Divya Srinivasan
We investigated age and gender differences in the perception and use of soft (Apex) vs. rigid (Paexo Back) passive back-support exoskeletons (BSE) for repetitive lifting and lowering. A gender-balanced sample of 20 young (18-30 years) and 16 old (45-60 years) individuals were recruited. In the first session, participants' self-reported maximum acceptable load (MAL) was assessed using a psychophysical approach. Changes in muscle activity and kinematics due to BSE use in repetitive lifting/lowering tasks were also assessed...
April 13, 2024: Ergonomics
https://read.qxmd.com/read/38612221/influence-of-an-engineered-notch-on-the-electromagnetic-radiation-performance-of-niti-shape-memory-alloy
#10
JOURNAL ARTICLE
Anu Anand, Rajeev Kumar, Shatrudhan Pandey, S M Mozammil Hasnain, Saurav Goel
This work explores the influence of a pre-engineered notch on the electromagnetic radiation (EMR) parameters in NiTi shape memory alloy (SMA) during tensile tests. The test data showed that the EMR signal fluctuated between oscillatory and exponential, signifying that the specimen's viscosity damping coefficient changes during strain hardening. The EMR parameters, maximum EMR amplitude, and average EMR energy release rate remained constant initially but rose sharply with the plastic zone radius with progressive loading...
April 8, 2024: Materials
https://read.qxmd.com/read/38612178/critical-assessment-of-novel-developments-in-hpgr-technology-using-dem
#11
JOURNAL ARTICLE
Victor A Rodriguez, Gabriel K P Barrios, Túlio M Campos, Luís Marcelo Tavares
Advances in high-pressure grinding roll (HGPR) technology since its first commercial application in the cement industry include new roll wear protection techniques and new confinement systems. The latter contribute to reductions in the edge effects in an attempt to reach a more homogenous product size along the rolls. Additional advances in this technology have been made in recent years, while modeling and simulation tools are also reaching maturity and can now be used to subject such novel developments to detailed scrutiny...
April 4, 2024: Materials
https://read.qxmd.com/read/38608772/development-of-a-flow-cell-bioreactor-for-immobilized-sulfidogenic-sludge-characterization-using-electrochemical-h-2-s-microsensors
#12
JOURNAL ARTICLE
Rebeca Castro, Gemma Gabriel, David Gabriel, Xavier Gamisans, Xavier Guimerà
The sulfate-reduction process plays a crucial role in the biological valorization of SOx gases. However, a complete understanding of the sulfidogenic process in bioreactors is limited by the lack of technologies for characterizing the sulfate-reducing activity of immobilized biomass. In this work, we propose a flow-cell bioreactor (FCB) for characterizing sulfate-reducing biomass using H2 S microsensors to monitor H2 S production in real-time within a biofilm. To replace natural immobilization through extracellular polymeric substance production, sulfidogenic sludge was artificially immobilized using polymers...
April 10, 2024: Chemosphere
https://read.qxmd.com/read/38607180/electrospun-fenoprofen-polycaprolactone-tranexamic-acid-hydroxyapatite-nanofibers-as-orthopedic-hemostasis-dressings
#13
JOURNAL ARTICLE
Chang Huang, Menglong Wang, Siyou Yu, Deng-Guang Yu, Sim Wan Annie Bligh
Dressings with multiple functional performances (such as hemostasis, promoting regeneration, analgesia, and anti-inflammatory effects) are highly desired in orthopedic surgery. Herein, several new kinds of medicated nanofibers loaded with several active ingredients for providing multiple functions were prepared using the modified coaxial electrospinning processes. With an electrospinnable solution composed of polycaprolactone and fenoprofen as the core working fluid, several different types of unspinnable fluids (including pure solvent, nanosuspension containing tranexamic acid and hydroxyapatite, and dilute polymeric solution comprising tranexamic acid, hydroxyapatite, and polyvinylpyrrolidone) were explored to implement the modified coaxial processes for creating the multifunctional nanofibers...
April 8, 2024: Nanomaterials
https://read.qxmd.com/read/38600917/behind-the-scenes-radiotherapy-technical-training-through-professionals-eyes
#14
JOURNAL ARTICLE
M Strasser, M H Senger
Training technical professionals for Radiotherapy is essential due to growing demand caused by early cancer diagnoses, global population aging, rising cancer rates, and evolving equipment and techniques. Our objective was to gather insights from graduates of various courses who are now working professionally, based on the principle that one way to assess educational training is by considering the attributes that trained and active professionals deem important in the improvement courses they have taken. A cross-sectional study (approved at the local Research Ethics Committee) was conducted, involving an online survey for the opinion of professionals already qualified as radiotherapy technicians or technologists and engaged in this work...
June 2024: Technical innovations & patient support in radiation oncology
https://read.qxmd.com/read/38599435/mucoadhesive-chitosan-poly-lactic-co-glycolic-acid-nanoparticles-for-intranasal-delivery-of-quetiapine-development-characterization-in-physiologically-relevant-3d-tissue-models
#15
JOURNAL ARTICLE
Dnyandev G Gadhave, Mural Quadros, Akanksha R Ugale, Mimansa Goyal, Seyoum Ayehunie, Vivek Gupta
Quetiapine hemifumarate (QF) delivery to the CNS via conventional formulations is challenging due to poor solubility and lower oral bioavailability (9 %). Similarly, many other second-generation antipsychotics, such as olanzapine, clozapine, and paliperidone, have also shown low oral bioavailability of <50 %. Hence, the present work was intended to formulate QF-loaded biodegradable PLGA-NPs with appropriate surface charge modification through poloxamer-chitosan and investigate its targeting potential on RPMI-2650 cell lines to overcome the limitations of conventional therapies...
April 8, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38595713/comprehensive-assessment-of-carbon-biomaterial-and-inorganic-based-adsorbents-for-the-removal-of-the-most-hazardous-heavy-metal-ions-from-wastewater
#16
REVIEW
Nashra Sheraz, Afzal Shah, Abdul Haleem, Faiza Jan Iftikhar
Owing to the high cost of recycling waste, underdeveloped countries discharge industrial, agricultural, and anthropogenic effluents without pretreatment. As a result, pollutant-loaded waste enters water bodies. Among the diverse toxic contaminants, heavy metal ions are the most detrimental because of their chronic toxicity, non-degradability, prevalence, and bioaccumulation. The growing shortage of water resources demands the removal of heavy metal ions from wastewater. Three SDGs of the sustainability agenda of the United Nations appeal for clean water to protect life beneath water and on land depending on the water sources...
April 3, 2024: RSC Advances
https://read.qxmd.com/read/38595183/top-down-attention-does-not-modulate-mechanical-hypersensitivity-consecutive-to-central-sensitization-insights-from-an-experimental-analysis
#17
JOURNAL ARTICLE
Delia Della Porta, Eléonore Scheirman, Valéry Legrain
According to the neurocognitive model of attention to pain, when the attentional resources invested in a task unrelated to pain are high, limited cognitive resources can be directed toward the pain. This is supported by experimental studies showing that diverting people's attention away from acute pain leads to experiencing less pain. Theoretical work has suggested that this phenomenon may present a top-down modulatory mechanism for persistent pain as well. However, conclusive empirical evidence is lacking...
April 3, 2024: Pain
https://read.qxmd.com/read/38591539/development-of-fsw-process-parameters-for-lap-joints-made-of-thin-7075-aluminum-alloy-sheets
#18
JOURNAL ARTICLE
Piotr Lacki, Anna Derlatka, Wojciech Więckowski, Janina Adamus
The article describes machine learning using artificial neural networks (ANNs) to develop the parameters of the friction stir welding (FSW) process for three types of aluminum joints (EN AW 7075). The ANNs were built using a total of 608 experimental data. Two types of networks were built. The first one was used to classify good/bad joints with MLP 7-19-2 topology (one input layer with 7 neurons, one hidden layer with 19 neurons, and one output layer with 2 neurons), and the second one was used to regress the tensile load-bearing capacity with MLP 7-19-1 topology (one input layer with 7 neurons, one hidden layer with 19 neurons, and one output layer with 1 neuron)...
January 30, 2024: Materials
https://read.qxmd.com/read/38590446/improved-recall-of-handover-information-in-a-simulated-emergency-a-randomised-controlled-trial
#19
JOURNAL ARTICLE
Paul Fischer, Robin Abendschein, Monika Berberich, Tobias Grundgeiger, Patrick Meybohm, Thorsten Smul, Oliver Happel
BACKGROUND: Handovers during medical emergencies are challenging due to time-critical, dynamic and oftentimes unorderly and distracting situations. We evaluated the effect of distraction-reduced clinical surroundings during handover on (1) the recall of handover information, (2) the recall of information from the surroundings and (3) self-reported workload in a simulated in-hospital cardiac arrest scenario. METHODS: In a parallel group design, emergency team leaders were randomly assigned to receive a structured handover of a cardio-pulmonary resuscitation (CPR) either inside the room ("inside group") right next to the ongoing CPR or in front of the room ("outside group") with no audio-visual distractions from the ongoing CPR...
June 2024: Resuscitation plus
https://read.qxmd.com/read/38585832/a-6-minute-limb-function-assessment-for-therapeutic-testing-in-experimental-peripheral-artery-disease-models
#20
Victoria R Palzkill, Jianna Tan, Abigail L Tice, Leonardo F Ferriera, Terence E Ryan
BACKGROUND: The translation of promising therapies from pre-clinical models of hindlimb ischemia (HLI) to patients with peripheral artery disease (PAD) has been inadequate. While this failure is multifactorial, primary outcome measures in preclinical HLI models and clinical trials involving patients with PAD are not aligned well. For example, laser Doppler perfusion recovery measured under resting conditions is the most used outcome in HLI studies, whereas clinical trials involving patients with PAD primarily assess walking performance...
March 27, 2024: bioRxiv
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