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Bruce S McEwen
Dirk Hellhammer and his colleagues have played a major role in creating the field of psychoneuroendocrinology from their roots in psychology. In this review, using examples from the history of the McEwen laboratory and neuroscience and neuroendocrinology colleagues, I summarize my own perspective as to how the fields of neuroscience and neuroendocrinology have contributed to psychoneuroendocrinology and how they converged with the contributions from Dirk Hellhammer and his colleagues.
September 12, 2018: Psychoneuroendocrinology
Nathalie Peiris, Maxie Blasini, Thelma Wright, Luana Colloca
The placebo effect is a complex phenomenon that can be described from neurobiological, psychosocial, and epistemological perspectives. Different leaders in the field have proposed multiple theories and models that attempt to describe both the nature and the mechanisms of action underlying placebo effects. This article focuses on the most relevant psychological models that have been suggested for characterizing the different mechanisms underlying the placebo effect. We outline how the dynamic psychoneurobiological aspects of the placebo phenomenon can be a potential reliable and useful tool in daily clinical practice for illness and symptom management within a wide variety of specialties and health-care practices...
2018: Perspectives in Biology and Medicine
Avshalom Galil, Jessica Yarmolovsky, Maor Gidron, Ronny Geva
Children's cheating and factors supporting honesty are not well understood. The current work explored variables involved in children's cheating through eye-tracking and an implicit manipulation in which extrinsic awareness of the effects of one's behaviors on others was primed. Participants played a computer game with the option for a monetary gain in which they could earn more if they selectively erred in response to more profitable stimuli. Results show that children cheat by making selective effort toward more profitable errors; however, extrinsic awareness inhibits these cheating behaviors...
October 3, 2018: Journal of Experimental Child Psychology
Gunther Meinlschmidt, Esther Stalujanis, Marion Tegethoff
Using vehicles with engaged automated driving systems (ADS) ('highly automated driving', HAD) will substantially impact on future society's mobility, yet the current understanding of human psychobiology related to HAD is still limited. Hence, we synthesized evidence on the psychobiology of subjects using HAD, informing an integrative model of the psychobiology of HAD, and providing guidance for reporting future research on this topic. We included (non-)randomized studies assessing human peripheral biology markers of in-vehicle-users in real or simulated driving environments, using vehicles with vs...
September 22, 2018: Psychoneuroendocrinology
Susen Heimbürge, Ellen Kanitz, Winfried Otten
The hair cortisol concentration (HCC) is assumed to be a retrospective marker of integrated cortisol secretion and stress over longer periods of time. Its quantification is increasingly used in psychoneuroendocrinological studies in humans, but also in animal stress and welfare research. The measurement of HCCs for the assessment of stress offers many considerable benefits for use in domesticated and wild animals, especially due to the easy and minimally invasive sampling procedure and the representation of longer time periods in one sample...
October 1, 2018: General and Comparative Endocrinology
Antti Huotarinen, Riku Kivisaari, Marwan Hariz
BACKGROUND: The widespread use of deep brain stimulation (DBS) for movement disorders has renewed the interest in DBS for psychiatric disorders. Lauri Laitinen was a pioneer of stereotactic psychosurgery in the 1950s to 1970s, especially by introducing the subgenual cingulotomy. Our aim here was to verify the anatomical target used by Laitinen, to report on a patient who underwent this procedure, and to review the literature. MATERIALS AND METHODS: The records of Helsinki University Hospital were searched for psychosurgical cases performed between 1970 and 1974...
October 2, 2018: Stereotactic and Functional Neurosurgery
Massimo Fioranelli, Anna G Bottaccioli, Francesco Bottaccioli, Maria Bianchi, Miriam Rovesti, Maria G Roccia
Recent findings have deeply changed the current view of coronary heart disease, going beyond the simplistic model of atherosclerosis as a passive process involving cholesterol build-up in the subintimal space of the arteries until their final occlusion and/or thrombosis and instead focusing on the key roles of inflammation and the immune system in plaque formation and destabilization. Chronic inflammation is a typical hallmark of cardiac disease, worsening outcomes irrespective of serum cholesterol levels. Low-grade chronic inflammation correlates with higher incidence of several non-cardiac diseases, including depression, and chronic depression is now listed among the most important cardiovascular risk factors for poor prognosis among patients with myocardial infarction...
2018: Frontiers in Immunology
Jens Hoebel, Thomas Lampert
Since the early 2000s, evidence has been accumulating that subjective social status - a person's sense of their own position on the social ladder - affects health above and beyond objective socioeconomic status. To date, however, little is known about how these distinct health effects of subjective social status can be explained. This article narratively reviews different explanatory approaches and key methodological challenges, backed up by empirical findings and supplemented by the authors' own reflections...
September 19, 2018: Journal of Health Psychology
Yeon-Hee Lee, Suk Chon
OBJECTIVE: The aim of this study was to investigate possible relationships among hematologic factors, psychological dimensions, the presence of self-reported sleep problems, and clinical characteristics in patients with burning mouth syndrome (BMS). METHODS: Twenty-five postmenopausal female patients with primary BMS (aged 55.2 ± 9.6 years) were included. All participants underwent clinical and psychological evaluations and blood sampling. The patients were subdivided according to the absence or presence of the self-reported sleep problems...
August 31, 2018: Cranio: the Journal of Craniomandibular Practice
Saideh Masafi, Seyed Hassan Saadat, Katayoun Tehranchi, Roohollah Olya, Mostafa Heidari, Saied Malihialzackerini, Mahdi Jafari, Ehsan Rajabi
BACKGROUND: Psychoneuroimmunology (PNI) is the study of the interaction between psychological processes and the nervous and immune systems of the human body. The impact of psychological factors on the immune system and the role of this system in Coronary Artery Disease (CAD) are confirmed. Coronary Heart Disease (CHD) is arisen due to the failure of blood and oxygen to the heart tissues. AIM: The present study aimed to describe psychoneuroimmunological processes which contribute to CAD and CHD progression...
August 20, 2018: Open Access Macedonian Journal of Medical Sciences
Andrew D Grotzinger, Daniel A Briley, Laura E Engelhardt, Frank D Mann, Megan W Patterson, Jennifer L Tackett, Elliot M Tucker-Drob, K Paige Harden
No abstract text is available yet for this article.
August 14, 2018: Psychoneuroendocrinology
Jens Gaab
Placebos are usually employed deceptively in clinical trials in order to control for non-specific effects. However, since placebos themselves have been found to cause clinically relevant changes and in some cases are indistinguishable from the verum they are tested against, this theoretically inert, but practically effective intervention has become a scientific discipline in its own right. In this review, it is argued that placebos are generic and genuine biopsychosocial interventions and as such are highly interesting candidates for a psychoneuroendocrinological perspective...
August 3, 2018: Psychoneuroendocrinology
Carlo Dal Lin, Francesco Tona, Elena Osto
The heart can be viewed not just as muscle pump but also as an important checkpoint for a complex network of nervous, endocrine, and immune signals. The heart is able to process neurological signals independently from the brain and to crosstalk with the endocrine and immune systems. The heart communicates with the psyche through the neuro-endocrine-immune system in a highly integrated way, in order to maintain the homeostasis of the whole body with peculiarities specific to males and females.
2018: Advances in Experimental Medicine and Biology
H Vallet, T Fali, D Sauce
Major progress in preventing, delaying or curing various pathologies normally encountered in old age results in a continuous improvement in life expectancy. However, understanding the underlying cause of the disparate comorbidities occurrence with aging remains a priority in order to propose adapted care for the older population. In one hand, aging profoundly impairs the immune system; it is characterized by many changes in haematopoiesis, adaptive and innate systems, and is associated with pro-inflammatory environment...
July 21, 2018: La Revue de Médecine Interne
QiLiang Chen, Haley E Calcagno, Mujeeb Shad
Background: Treatment-resistant aggressive behavior is a complex psychoneurological phenomenon with high health care and societal costs commonly observed in mental illnesses involving psychosis. Here, we report a preliminary evaluation of treatment with dextromethorphan/quinidine in 4 adult patients with significant history of psychosis-related aggression and impulsive behaviors. Methods: The files of 4 inpatients with DSM-5-defined psychotic disorder and treatment-resistant aggression treated at the Oregon State Hospital (Salem, Oregon) between June and November of 2017 were retrospectively analyzed...
June 28, 2018: Primary Care Companion to CNS Disorders
Maira Giannelou, Dimitrios Tseronis, Eleni Antypa, Clio P Mavragani
Objectives: Patients with systemic lupus erythematosus (SLE) are characterized by increased cardiovascular disease (CVD) risk as well as heightened rates of psychological distress. Since a link between psychological issues and CV morbidity has been previously suggested, the influence of psychological burden on subclinical atherosclerosis in SLE patients was investigated. Methods: 71 SLE patients were assessed for the presence of subclinical atherosclerosis-defined either as carotid and/or femoral plaque formation or arterial wall thickening [Intima Media Thickness (IMT) levels > 0...
2018: Frontiers in Psychiatry
Mária Resch
Among the various etiological theories (e.g., psychosomatic stress) the addictive model of obesity has also been described. Those suffering from eating disorders triggered by emotional causes (in consequence of the reward system) tend to grab a snack mostly out of happiness. The aim of the present study was to examine the addictive model of obesity so that the relationships identified here could help provide more accurate treatments to those suffering from being overweight. This study identifies the anatomical, neurobiological and psychic relationships between the etiological factors from the aspect of the addictive model of obesity so that further logical relationships could be confirmed based on the conclusions drawn here...
July 2018: Orvosi Hetilap
Kawther Ismail Hamash, Wendy Umberger, Aynur Aktas, Declan Walsh, Vinay K Cheruvu
BACKGROUND: Pain, depression, anxiety, sleep disturbances, and constipation were reported in different symptom clusters at different stages of breast cancer. Managing symptom clusters rather than individual symptoms can improve performance status. AIM: The study examined the effect of pain symptom cluster (pain and constipation) on performance when mediated by the psychoneurological symptom cluster (depression, anxiety, and sleep disturbances) using age as a moderator...
June 21, 2018: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
Carey S Clark
With the knowledge of psychoneuroimmunological responses and the known high stress levels of nursing students, as caring nurse educators, we have become ethically obligated to revise and re-vision our current nursing educational practices. Nurse educators should be motivated to create innovative and radical caring science curricular approaches, so that our nurses of the future are in turn supported in creating caring- healing sustainable bedside practices. This paper details the outcomes from an upper level yoga elective in an RN- BSN program...
June 13, 2018: International Journal of Nursing Education Scholarship
Pooja Patnaik Kuppili, Nivedhitha Selvakumar, Vikas Menon
We describe a case of 45-year-old female suffering from chronic hepatitis B and bronchial asthma who presented with symptoms of seasonal affective disorder and sickness behavior. The case report illustrates syndromal and sub syndromal presentations of depression such as sickness behavior in support of "malaise theory of depression" from psychoneuroimmunological perspective. The current case depicts the complex interplay of inflammatory physical illness, medication and manifestations of depression in an individual case...
May 2018: Indian Journal of Psychological Medicine
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