keyword
MENU ▼
Read by QxMD icon Read
search

Valerian

keyword
https://www.readbyqxmd.com/read/28230382/animalistic-dehumanization-of-older-people-by-younger-ones-variations-of-humanness-perceptions-as-a-function-of-a-target-s-age
#1
Valérian Boudjemadi, Stéphanie Demoulin, Jennifer Bastart
The present work investigated associations of older people with humanness. Focusing on complementary approaches (attribute-based, metaphor-based, and target-based), 4 studies tested the hypothesis that older people are the targets of animalistic dehumanization. Using an emotional attribution task, Study 1 (N = 112) explored infrahumanization and shows that young participants attributed more uniquely human emotions to young people than to older ones. No such effect occurred with regards to nonuniquely human emotions...
February 23, 2017: Psychology and Aging
https://www.readbyqxmd.com/read/28212735/elimination-of-the-unnecessary-intra-and-extracellular-signaling-by-anionic-phospholipids
#2
REVIEW
Valerian E Kagan, Hülya Bayır, Yulia Y Tyurina, Sergey B Bolevich, John J Maguire, Bengt Fadeel, Krishnakumar Balasubramanian
High fidelity of biological systems is frequently achieved by duplication of the essential intracellular machineries or, removal of the entire cell, which becomes unnecessary or even harmful in altered physiological environments. Carefully controlled removal of these cells, without damaging normal cells, requires precise signaling, and is critical to maintaining homeostasis. This review describes how two anionic phospholipids - phosphatidylserine (PS) and cardiolipin (CL) - residing in distinct compartments of the cell, signal removal of "the unnecessary" using several uniform principles...
January 15, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28208737/special-issue-on-ruthenium-complexes
#3
EDITORIAL
Ileana Dragutan, Valerian Dragutan, Albert Demonceau
The organic chemistry of ruthenium has been one of the most vigorously growing research areas over the past decades. Considerable effort has been extended towards the design and application of a broad series of ruthenium complexes, which culminated with the development by Ryoji Noyori (2001 Nobel Prize for Chemistry) of chiral ruthenium catalysts for stereoselective hydrogenation reactions [1], and the discovery by Robert H. Grubbs (2005 Nobel Prize for Chemistry) of well-defined ruthenium- benzylidene catalysts for olefin metathesis [2] [...
February 8, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28177787/-i-i-sporicidal-efficacy-of-thermal-sprayed-copper-alloy-coating
#4
Romina Shafaghi, Javad Mostaghimi, Valerian Pershin, Maurice Ringuette
Approximately 200,000 Canadians acquire healthcare-associated bacterial infections each year and several-fold more acquire food-borne bacterial illnesses.  Bacterial spores are particularly problematic as they survive several months on surfaces.  Due to its sporicidal activity, copper sheet metal is sometimes used in hospital settings but widespread use is limited by cost and incompatibility with complex furniture/instrument design and topographies.  A potential alternative is the use of thermal spray technology to coat surfaces with copper alloys...
January 19, 2017: Canadian Journal of Microbiology
https://www.readbyqxmd.com/read/28148447/les-droits-des-patients-en-fin-de-vie
#5
Valériane Dujardin
No abstract text is available yet for this article.
August 2016: Revue de L'infirmière
https://www.readbyqxmd.com/read/28096376/myosin-driven-transport-network-in-plants
#6
Elizabeth G Kurth, Valera V Peremyslov, Hannah L Turner, Kira S Makarova, Jaime Iranzo, Sergei L Mekhedov, Eugene V Koonin, Valerian V Dolja
We investigate the myosin XI-driven transport network in Arabidopsis using protein-protein interaction, subcellular localization, gene knockout, and bioinformatics analyses. The two major groups of nodes in this network are myosins XI and their membrane-anchored receptors (MyoB) that, together, drive endomembrane trafficking and cytoplasmic streaming in the plant cells. The network shows high node connectivity and is dominated by generalists, with a smaller fraction of more specialized myosins and receptors...
January 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28074841/the-mito-damp-cardiolipin-blocks-il-10-production-causing-persistent-inflammation-during-bacterial-pneumonia
#7
Krishnendu Chakraborty, Mahesh Raundhal, Bill B Chen, Christina Morse, Yulia Y Tyurina, Anupriya Khare, Timothy B Oriss, Rachael Huff, Janet S Lee, Claudette M St Croix, Simon Watkins, Rama K Mallampalli, Valerian E Kagan, Anuradha Ray, Prabir Ray
Bacterial pneumonia is a significant healthcare burden worldwide. Failure to resolve inflammation after infection precipitates lung injury and an increase in morbidity and mortality. Gram-negative bacteria are common in pneumonia and increased levels of the mito-damage-associated molecular pattern (DAMP) cardiolipin can be detected in the lungs. Here we show that mice infected with Klebsiella pneumoniae develop lung injury with accumulation of cardiolipin. Cardiolipin inhibits resolution of inflammation by suppressing production of anti-inflammatory IL-10 by lung CD11b(+)Ly6G(int)Ly6C(lo)F4/80(+) cells...
January 11, 2017: Nature Communications
https://www.readbyqxmd.com/read/28039782/reduced-sensitivity-to-social-priors-during-action-prediction-in-adults-with-autism-spectrum-disorders
#8
Valerian Chambon, Chlöé Farrer, Elisabeth Pacherie, Pierre O Jacquet, Marion Leboyer, Tiziana Zalla
An extensive amount of evidence has documented a diminished ability to predict and understand other people's action in individuals with autism spectrum disorders (ASD). Recently, two theoretical accounts, the "Hypo-priors" and the "Aberrant precision" hypotheses, have suggested that attenuated Bayesian priors or an imbalance of the precision ascribed to sensory evidence relative to prior expectations may be responsible for the atypical perceptual experience and difficulties with action understanding in ASD...
March 2017: Cognition
https://www.readbyqxmd.com/read/27982579/lipidomics-characterization-of-biosynthetic-and-remodeling-pathways-of-cardiolipins-in-genetically-and-nutritionally-manipulated-yeast-cells
#9
Yulia Y Tyurina, Wenjia Lou, Feng Qu, Vladimir A Tyurin, Dariush Mohammadyani, Jenney Liu, Maik Hüttemann, Michael A Frasso, Peter Wipf, Hülya Bayir, Miriam L Greenberg, Valerian E Kagan
Cardioipins (CLs) are unique tetra-acylated phospholipids of mitochondria and define the bioenergetics and regulatory functions of these organelles. An unresolved paradox is the high uniformity of CL molecular species (tetra-linoleoyl-CL) in the heart, liver, and skeletal muscles-in contrast to their high diversification in the brain. Here, we combined liquid chromatography-mass-spectrometry-based phospholipidomics with genetic and nutritional manipulations to explore CLs' biosynthetic vs postsynthetic remodeling processes in S...
December 16, 2016: ACS Chemical Biology
https://www.readbyqxmd.com/read/27976277/quality-control-of-valerian-products-by-hplc-fingerprint-analysis
#10
E M Gonulalan, E Nemutlu, L O Demirezer
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27935971/costs-of-care-of-hiv-infected-children-initiating-lopinavir-ritonavir-based-antiretroviral-therapy-before-the-age-of-two-in-cote-d-ivoire
#11
Sophie Desmonde, Divine Avit, Junie Petit, Madeleine Amorissani Folquet, Francois Tanoh Eboua, Clarisse Amani Bosse, Evelyne Dainguy, Véronique Mea, Marguerite Timite-Konan, Sylvie Ngbeché, Andrea Ciaranello, Valeriane Leroy
OBJECTIVES: To access the costs of care for Ivoirian children before and after initiating LPV/r-based antiretroviral therapy (ART) before the age of two. METHODS: We assessed the direct costs of care for all HIV-infected children over the first 12 months on LPV/r-based ART initiated <2 years of age in Abidjan. We recorded all drug prescriptions, ART and cotrimoxazole prophylaxis delivery, medical analyses/examinations and hospital admissions. We compared these costs to those accrued in the month prior to ART initiation...
2016: PloS One
https://www.readbyqxmd.com/read/27930403/has-the-phasing-out-of-stavudine-in-accordance-with-changes-in-who-guidelines-led-to-a-decrease-in-single-drug-substitutions-in-first-line-antiretroviral-therapy-for-hiv-in-sub-saharan-africa
#12
Alana T Brennan, Mary-Ann Davies, Jacob Bor, Gilles Wandeler, Kathryn Stinson, Robin Wood, Hans Prozesky, Frank Tanser, Geoffrey Fatti, Andrew Boulle, Izukanji Sikazwe, Kara Wools-Kaloustian, Constantin Yiannoutsos, Valériane Leroy, Nathalie de Rekeneire, Matthew P Fox
OBJECTIVE: We assessed the relationship between phasing out stavudine in first-line antiretroviral therapy (ART) in accordance with WHO 2010 policy and single-drug substitutions (SDS) (substituting the nucleoside reverse transcriptase inhibitor in first-line ART) in sub-Saharan Africa. DESIGN: Prospective cohort analysis (International epidemiological Databases to Evaluate AIDS-Multiregional) including ART-naive, HIV-infected patients aged at least 16 years, initiating ART between January 2005 and December 2012...
January 2, 2017: AIDS
https://www.readbyqxmd.com/read/27898089/polarisation-independent-silicon-on-insulator-slot-waveguides
#13
Valerian Hongjie Chen, Jun Rong Ong, Ching Eng Png
The minimisation of birefringence, or polarisation mode dispersion, is vital for simplifying and miniaturising photonic components. In this work, we present a systematic study of the slot waveguide geometries required for having zero birefringence (ZB). We show that the rail widths required for ZB are more strongly dependent on the height of the waveguide than on the slot separation. After which, we demonstrate that the ZB geometry is significantly affected by the slanting of the waveguide walls. This paper proceeds to show that within the range studied, one can fix the height, slot, slant angle, and bend radius, and still achieve ZB by varying the widths of both of the rails...
November 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27850378/740-inhibition-of-ferroptosis-as-a-neuroprotective-strategy-following-traumatic-brain-injury
#14
Elizabeth Kenny, Qin Yang, Emin Fidan, Lee Ann New, Tamil Selvan Anthonymuthu, Patrick Kochanek, Valerian Kagan, Hulya Bayir
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27794421/a-topical-mitochondria-targeted-redox-cycling-nitroxide-mitigates-oxidative-stress-induced-skin-damage
#15
Rhonda M Brand, Michael W Epperly, J Mark Stottlemyer, Erin M Skoda, Xiang Gao, Song Li, Saiful Huq, Peter Wipf, Valerian E Kagan, Joel S Greenberger, Louis D Falo
Skin is the largest human organ, and it provides a first line of defense that includes physical, chemical, and immune mechanisms to combat environmental stress. Radiation is a prevalent environmental stressor. Radiation-induced skin damage ranges from photoaging and cutaneous carcinogenesis caused by UV exposure, to treatment-limiting radiation dermatitis associated with radiotherapy, to cutaneous radiation syndrome, a frequently fatal consequence of exposures from nuclear accidents. The major mechanism of skin injury common to these exposures is radiation-induced oxidative stress...
October 26, 2016: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/27780544/isolation-of-human-trophoblastic-extracellular-vesicles-and-characterization-of-their-cargo-and-antiviral-activity
#16
Yingshi Ouyang, Avraham Bayer, Tianjiao Chu, Vladimir A Tyurin, Valerian E Kagan, Adrian E Morelli, Carolyn B Coyne, Yoel Sadovsky
INTRODUCTION: Primary human trophoblasts release a repertoire of extracellular vesicles (EVs). Among them are nano-sized exosomes, which we found to suppress the replication of a wide range of diverse viruses. These exosomes contain trophoblastic microRNAs (miRNAs) that are expressed from the chromosome 19 miRNA cluster and exhibit antiviral properties. Here, we report our investigation of the cargo of placental EVs, focusing on the composition and the antiviral properties of exosomes, microvesicles, and apoptotic blebs...
November 2016: Placenta
https://www.readbyqxmd.com/read/27776039/has-the-phasing-out-of-stavudine-in-accordance-with-changes-in-who-guidelines-led-to-a-decrease-in-single-drug-substitutions-in-first-line-antiretroviral-therapy-for-hiv-in-sub-saharan-africa
#17
Alana T Brennan, Mary-Ann Davies, Jacob Bor, Gilles Wandeler, Kathryn Stinson, Robin Wood, Hans Prozesky, Frank Tanser, Geoffrey Fatti, Andrew Boulle, Izukanji Sikazwe, Kara Wool-Kaloustian, Constantin Yuannoutsos, Valériane Leroy, Nathalie de Rekeneire, Matthew P Fox
OBJECTIVE: We assessed the relationship between phasing out stavudine in first-line antiretroviral therapy (ART) in accordance with WHO 2010 policy and single-drug substitutions (SDS) (substituting the nucleoside reverse transcriptase inhibitor in first-line ART) in sub-Saharan Africa. DESIGN: Prospective cohort analysis (International epidemiological Databases to Evaluate AIDS-Multiregional) including ART-naive, HIV-infected patients aged at least 16 years, initiating ART between January 2005 and December 2012...
January 2, 2017: AIDS
https://www.readbyqxmd.com/read/27771032/complications-and-surgical-outcomes-after-interhospital-transfer-vs-direct-admission-in-colorectal-surgery-a-national-surgical-quality-improvement-program-analysis
#18
Stephen P Sharp, Ashar Ata, Brian T Valerian, Jonathan J Canete, A David Chismark, Edward C Lee
BACKGROUND: Interhospital transfer is common among patients undergoing colorectal surgery. The purpose of this study was to determine surgical outcomes after transfer vs direct admission in patients undergoing colorectal surgery. METHODS: The American College of Surgeons National Surgical Quality Improvement Program database from 2010 to 2012 was used. Colorectal operations were selected, including both emergency and nonemergency cases. Transfers were compared with direct admissions using a complex comorbidity analysis model...
September 2, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27758862/phosphorylation-of-cytochrome-c-threonine-28-regulates-electron-transport-chain-activity-in-kidney-implications-for-amp-kinase
#19
Gargi Mahapatra, Ashwathy Varughese, Qinqin Ji, Icksoo Lee, Jenney Liu, Asmita Vaishnav, Christopher Sinkler, Alexandr A Kapralov, Carlos T Moraes, Thomas H Sanderson, Timothy L Stemmler, Lawrence I Grossman, Valerian E Kagan, Joseph S Brunzelle, Arthur R Salomon, Brian F P Edwards, Maik Hüttemann
Mammalian cytochrome c (Cytc) plays a key role in cellular life and death decisions, functioning as an electron carrier in the electron transport chain and as a trigger of apoptosis when released from the mitochondria. However, its regulation is not well understood. We show that the major fraction of Cytc isolated from kidneys is phosphorylated on Thr(28), leading to a partial inhibition of respiration in the reaction with cytochrome c oxidase. To further study the effect of Cytc phosphorylation in vitro, we generated T28E phosphomimetic Cytc, revealing superior behavior regarding protein stability and its ability to degrade reactive oxygen species compared with wild-type unphosphorylated Cytc Introduction of T28E phosphomimetic Cytc into Cytc knock-out cells shows that intact cell respiration, mitochondrial membrane potential (ΔΨm), and ROS levels are reduced compared with wild type...
January 6, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27751669/review-of-safety-and-efficacy-of-sleep-medicines-in-older-adults
#20
REVIEW
Jennifer L Schroeck, James Ford, Erin L Conway, Kari E Kurtzhalts, Megan E Gee, Krista A Vollmer, Kari A Mergenhagen
PURPOSE: Insomnia is problematic for older adults. After behavioral modifications fail to show adequate response, pharmacologic options are used. The pharmacokinetics of agents used to treat insomnia may be altered. This review focuses on the safety and efficacy of medications used to treat insomnia. METHODS: A literature search of Medline, PubMed, and Embase was conducted (January 1966-June 2016). It included systematic reviews, randomized controlled trials, observational studies, and case series that had an emphasis on insomnia in an older population...
November 2016: Clinical Therapeutics
keyword
keyword
16034
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"