Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
JOURNAL ARTICLE
Minyue Yin, Rufa Zhang, Jiaxi Lin, Shiqi Zhu, Lu Liu, Xiaolin Liu, Jianying Lu, Chunfang Xu, Jinzhou Zhu
BACKGROUND: Deep learning (DL) models perform poorly when there are limited gastric signet ring cell carcinoma (SRCC) samples. Few-shot learning (FSL) can address the small sample problem. METHODS: EfficientNetV2-S was first pretrained on ImageNet and then pretrained on esophageal endoscopic images (i.e., base classes: normal vs. early cancer vs. advanced cancer) using transfer learning. Second, images of gastric benign ulcers, adenocarcinoma and SRCC, i.e., novel classes (n = 50 per class), were included...
July 14, 2023: Digestive and Liver Disease
#22
Wei Jiang, Genshan Zhang, Haijie Li, Xiangshang Xu, Lingwei Jia, Xuelai Luo, Zhixin Cao
Synchronous gastrointestinal multiple primary tumors including gastric, colonic, and rectal cancers are rare. Moreover, it was a challenge to find an appropriate procedure without negatively impacting the overall outcome. We described the case of a 63-year-old woman who presented with a 4 month history of upper abdominal pain, acid regurgitation, and anemia. Gastroscopy with biopsy suggested early cancer of gastric antrum. Abdominal contrast-enhanced computerized tomography and colonoscopy revealed ascending colon and rectum tumors...
2023: Open Medicine (Warsaw, Poland)
#23
JOURNAL ARTICLE
Liling Peng, Yi Liao, Rui Zhou, Yan Zhong, Han Jiang, Jing Wang, Yu Fu, Le Xue, Xiaohui Zhang, Mingxiang Sun, Gang Feng, Zhaoting Meng, Sisi Peng, Xuexin He, Gaojun Teng, Xin Gao, Hong Zhang, Mei Tian
PURPOSE: PET/MRI has become an important medical imaging approach in clinical practice. In this study, we retrospectively investigated the detectability of fluorine-18 (18 F)-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ([18 F]FDG PET/MRI) combined with chest computerized tomography (CT) for early cancer in a large cohort of asymptomatic subjects. METHODS: This study included a total of 3020 asymptomatic subjects who underwent whole-body 18 F- PET/MRI and chest HRCT examinations...
July 4, 2023: European Journal of Nuclear Medicine and Molecular Imaging
#24
JOURNAL ARTICLE
Ai-Rui Jiang, Li-Ming Wen, Jian-Wei Ding, Rui-Zheng Zou, Xu-Biao Nie, Hui Lin, Jing Chen, Wei-Sen Zhang, Liang-Ying Dan, Yu-Xia Zhu, Chun-Mei Ren, Ying-Yang Wu, Lin-Lin Sheng, Ding-Rong Chen, Guo-Bin Liao, Hai-Yan Zhao, Jian-Jun Li, Ying Zuo, Jie Chen, Shuang Yu, Liang-Bi Xu, Jian-Ying Bai
BACKGROUND AND AIMS: Magnifying image-enhanced endoscopy (MIEE) is an advanced endoscopy with image-enhancement and magnification used in preoperative examination. However, its impact on the detection rate is unknown. METHODS: We conducted an open-label, randomized, parallel (1:1:1) controlled trial in six hospitals in China. Patients were recruited between February 14, 2022, and July 30, 2022. Eligible patients were ≥ 18, undergoing gastroscopy in outpatient departments...
July 1, 2023: Gastrointestinal Endoscopy
#25
Vincent Zimmer, Bert Bier
No abstract text is available yet for this article.
June 2023: GE Portuguese Journal of Gastroenterology
#26
JOURNAL ARTICLE
Sachin Wani, Dag Holmberg, Giola Santoni, Joonas H Kauppila, Martti Farkkila, My von Euler-Chelpin, Nicholas J Shaheen, Jesper Lagergren
BACKGROUND & AIMS: Post-endoscopy esophageal adenocarcinoma (PEEC) and post-endoscopy esophageal neoplasia (PEEN) undermine early cancer detection in Barrett's esophagus (BE). We aimed to assess the magnitude and conduct time-trend analysis of PEEC and PEEN among patients with newly diagnosed BE. METHODS: This population-based cohort study was conducted in Denmark, Finland, and Sweden between 2006 and 2020 and included 20,588 patients with newly diagnosed BE...
October 2023: Gastroenterology
#27
REVIEW
Shi-Wei Guan, Quan Lin, Hai-Bo Yu
Pancreatic cancer is a high mortality malignancy with almost equal mortality and morbidity rates. Both normal and tumour tissues of the pancreas were previously considered sterile. In recent years, with the development of technologies for high-throughput sequencing, a variety of studies have revealed that pancreatic cancer tissues contain small amounts of bacteria and fungi. The intratumour microbiome is being revealed as an influential contributor to carcinogenesis. The intratumour microbiome has been identified as a crucial factor for pancreatic cancer progression, diagnosis, and treatment, chemotherapy resistance, and immune response...
May 15, 2023: World Journal of Gastrointestinal Oncology
#28
JOURNAL ARTICLE
Nastazja D Pilonis, Maria O'Donovan, Susan Richardson, Rebecca C Fitzgerald, Massimiliano di Pietro
BACKGROUND: Recognition of early signet-ring cell carcinoma (SRCC) in patients with hereditary diffuse gastric cancer (HDGC) undergoing endoscopic surveillance is challenging. We hypothesized that probe-based confocal laser endomicroscopy (pCLE) might help diagnose early cancerous lesions in the context of HDGC. The aim of this study was to identify pCLE diagnostic criteria for early SRCC. METHODS: Patients with HDGC syndrome were prospectively recruited and pCLE assessment was performed on areas suspicious for early SRCC and control regions during an endoscopic surveillance procedure...
May 23, 2023: BMC Gastroenterology
#29
JOURNAL ARTICLE
Yixin Chen, Wan He, Min Chen, Lizhong Zhao, Jianyong Shao, Shiyong Lin, Baoqin Li, Hualin Xu, Ronghui Li, Jun Feng, Ning Liang, Yue Meng, Xiaojie Cheng, Weihua Zhang, Haoyang Yu, Ruilian Xu
OBJECTIVE: This study seeks to assess the efficacy of exfoliated colonocytes isolated from feces (ECIF) miR-92a as a clinical colorectal cancer diagnostic marker in a larger cohort. METHODS: Clinicopathologic data from colorectal cancer patients and health controls that underwent colonoscopy, as well as patients of other cancers diagnosed, were included. A total of 963 Chinese participants were enrolled, with 292 (27.4%) having colorectal cancer, 140 (14.5%) having other types of cancer, e...
2023: American Journal of Translational Research
#30
JOURNAL ARTICLE
Takashi Kawai, Haruhiro Inoue, Kenshi Yao, Mitsuru Kaise, Mototsugu Kato, Satoshi Tanabe, Yasuhisa Sakata
We held four upper gastrointestinal tract advanced diagnostic endoscopy sessions from the 89th to the 92nd Congress of the Japan Gastroenterological Endoscopy Society. The most common region addressed was the stomach in 25 presentations, followed by the esophagus in 23, duodenum in five, and other in one. Looking at techniques discussed, the most common image enhancement method discussed was narrowband imaging in 29 presentations, blue laser imaging, and linked color imaging (LCI) in 10 each, dual red imaging in three, and autofluorescence imaging in one...
May 14, 2023: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
#31
JOURNAL ARTICLE
Xiufeng Su, Qingshan Liu, Xiaozhong Gao, Liyong Ma
BACKGROUND: A timely diagnosis of early gastric cancer (EGC) can greatly reduce the death rate of patients. However, the manual detection of EGC is a costly and low-accuracy task. The artificial intelligence (AI) method based on deep learning is considered as a potential method to detect EGC. AI methods have outperformed endoscopists in EGC detection, especially with the use of the different region convolutional neural network (RCNN) models recently reported. However, no studies compared the performances of different RCNN series models...
April 13, 2023: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
#32
REVIEW
Vikneswaran Namasivayam, Noriya Uedo
Gastroscopy is the reference standard for the diagnosis of gastric cancer, but it is operator-dependent and associated with missed gastric cancer. The proliferation of gastroscopic examinations, increasingly for the screening and detection of subtle premalignant lesions, has motivated scrutiny of quality in gastroscopy. The concept of a high-quality endoscopic examination for the detection of superficial gastric neoplasia has been defined by expert guidelines to improve mucosal visualization, engender a systematic examination process and detect superficial neoplasia...
April 2023: DEN Open
#33
REVIEW
Paul David, Anke Mittelstädt, Dina Kouhestani, Anna Anthuber, Christoph Kahlert, Kai Sohn, Georg F Weber
Worldwide, gastrointestinal (GI) cancers account for a significant amount of cancer-related mortality. Tests that allow an early diagnosis could lead to an improvement in patient survival. Liquid biopsies (LBs) due to their non-invasive nature as well as low risk are the current focus of cancer research and could be a promising tool for early cancer detection. LB involves the sampling of any biological fluid (e.g., blood, urine, saliva) to enrich and analyze the tumor's biological material. LBs can detect tumor-associated components such as circulating tumor DNA (ctDNA), extracellular vesicles (EVs), and circulating tumor cells (CTCs)...
March 23, 2023: Cancers
#34
JOURNAL ARTICLE
Kotaro Sugawara, Takashi Fukuda, Yutaka Kishimoto, Daiji Oka, Yoshiyuki Kawashima, Naoko Inoshita, Hiroaki Kanda
Adenocarcinoma (AC) with neuroendocrine carcinoma (NEC) or enteroblastic (ENT) differentiation rarely develops in Barrett's esophagus (BE). A 76-year-old man was diagnosed with Barrett's AC (cT1bN0M0) and underwent thoracoscopic esophagectomy. A type 0-IIc + 0-Is lesion measuring 26 × 21 mm was macroscopically observed on a background of long segment BE (pT1bN0M0). The tumor comprised three different histological types of carcinoma (NEC, AC with ENT differentiation and moderately differentiated AC)...
August 2023: Clinical Journal of Gastroenterology
#35
JOURNAL ARTICLE
David Haan, Anna Bergamaschi, Verena Friedl, Gulfem D Guler, Yuhong Ning, Roman Reggiardo, Michael Kesling, Micah Collins, Bill Gibb, Kyle Hazen, Steve Bates, Michael Antoine, Carolina Fraire, Vanessa Lopez, Roger Malta, Maryam Nabiyouni, Albert Nguyen, Tierney Phillips, Michael Riviere, Anna Leighton, Christopher Ellison, Erin McCarthy, Aaron Scott, Lauren Gigliotti, Eric Nilson, Judith Sheard, Melissa Peters, Kelly Bethel, Shimul Chowdhury, Wayne Volkmuth, Samuel Levy
BACKGROUND & AIMS: Early detection of pancreatic cancer (PaC) can drastically improve survival rates. Approximately 25% of subjects with PaC have type 2 diabetes diagnosed within 3 years prior to the PaC diagnosis, suggesting that subjects with type 2 diabetes are at high risk of occult PaC. We have developed an early-detection PaC test, based on changes in 5-hydroxymethylcytosine (5hmC) signals in cell-free DNA from plasma. METHODS: Blood was collected from 132 subjects with PaC and 528 noncancer subjects to generate epigenomic and genomic feature sets yielding a predictive PaC signal algorithm...
March 24, 2023: Clinical Gastroenterology and Hepatology
#36
JOURNAL ARTICLE
Bo Jin, Xiaoliang Jin, Liang Huang, Chunli Zhang, Bin Lyu
Magnifying endoscopy is advantageous in detecting precancerous lesions. Our study aimed to clarify its ability to detect easily missed neoplastic lesions on the upper gastrointestinal tract. A retrospective analysis of clinical, endoscopic, and pathological data of cases undergoing gastroscopy was performed using magnifying and routine endoscopy. The detection rates of overall lesions, the ability to identify flat-type neoplastic lesions, and the easily missed neoplastic lesions were compared between the two groups...
March 15, 2023: Surgical Endoscopy
#37
JOURNAL ARTICLE
Mengshi Liu, Yali Yue, Yahui Wang, Yi Liang
BACKGROUND: Endoscopic mucosal dissection (EMD) is a new treatment method. Whether its clinical efficacy and safety are superior to surgical resection is still controversial. The sample size of previous studies on EMD for the treatment of early cancer of digestive tract is small, and there is no reliable evidence at present. Therefore, it is necessary to evaluate the efficacy and safety of EMD based on the evidence of evidence-based medicine. METHODS: The PubMed, Web of Science, Cochrane Library, Embase, China National Knowledge Infrastructure, Wanfang, cqvip...
February 28, 2023: Journal of Gastrointestinal Oncology
#38
REVIEW
Wei Han, Rui Kong, Nan Wang, Wen Bao, Xinli Mao, Jie Lu
Esophageal and gastric cancers are common diseases with high morbidity and mortality; thus, early detection and treatment are beneficial to improve prognosis. Confocal laser endomicroscopy (CLE) is a novel imaging technique that permits the histological analysis of tissues during endoscopy. CLE has been shown to uniquely affect the diagnosis of early upper gastrointestinal cancers. Relevant literature was searched using PubMed and Google Scholar databases. Despite inherent flaws, CLE can reduce tissue damage and improve diagnostic accuracy to a certain extent...
January 26, 2023: Cancers
#39
Martin S Taylor, Connie Wu, Peter C Fridy, Yasmeen Senussi, Wen-Chih Cheng, John Heaps, Kei Mori, Limor Cohen, Kelly R Molloy, Brian T Chait, Michael Goggins, Irun Bhan, Joseph W Franses, Xiaoyu Yang, Mary-Ellen Taplin, Xinan Wang, David C Christiani, Bruce E Johnson, Matthew Meyerson, Ravindra Uppaluri, Ann Marie Egloff, Elyssa N Denault, Laura M Spring, Tian-Li Wang, Ie-Ming Shih, Euihye Jung, Kshitij S Arora, Lawrence R Zukerberg, Osman H Yilmaz, Gary Chi, Bryanna L Norden, Yuhui Song, Linda Nieman, Aparna R Parikh, Matthew Strickland, Tomas Mustelin, George Eng, Ömer H Yilmaz, Ursula A Matulonis, Steven J Skates, Bo R Rueda, Ronny Drapkin, Samuel J Klempner, Vikram Deshpande, David T Ting, Michael P Rout, John LaCava, David R Walt, Kathleen H Burns
Improved biomarkers are needed for early cancer detection, risk stratification, treatment selection, and monitoring treatment response. While proteins can be useful blood-based biomarkers, many have limited sensitivity or specificity for these applications. Long INterspersed Element-1 (LINE-1, L1) open reading frame 1 protein (ORF1p) is a transposable element protein overexpressed in carcinomas and high-risk precursors during carcinogenesis with negligible detectable expression in corresponding normal tissues, suggesting ORF1p could be a highly specific cancer biomarker...
January 25, 2023: bioRxiv
#40
JOURNAL ARTICLE
Xian-Zhu Zhou, Nong-Hua Lyu, Hui-Yun Zhu, Quan-Cai Cai, Xiang-Yu Kong, Pei Xie, Li-Ya Zhou, Song-Ze Ding, Zhao-Shen Li, Yi-Qi Du
BACKGROUND AND AIMS: Current practice on Helicobacter pylori infection mostly focuses on individual-based care in the community, but family-based H. pylori management has recently been suggested as a better strategy for infection control. However, the family-based H. pylori infection status, risk factors and transmission pattern remain to be elucidated. METHODS: From September 2021 to December 2021, 10 735 families (31 098 individuals) were enrolled from 29 of 31 provinces in mainland China to examine family-based H...
May 2023: Gut
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
