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https://www.readbyqxmd.com/read/29912319/antagonism-and-antibiotic-resistance-drive-a-species-specific-plant-microbiota-differentiation-in-echinacea-spp
#1
Valentina Maggini, Elisangela Miceli, Camilla Fagorzi, Isabel Maida, Marco Fondi, Elena Perrin, Alessio Mengoni, Patrizia Bogani, Carolina Chiellini, Stefano Mocali, Arturo Fabiani, Francesca Decorosi, Luciana Giovannetti, Fabio Firenzuoli, Renato Fani
A key factor in the study of plant-microbes interaction is the composition of plant microbiota, but little is known about the factors determining its functional and taxonomic organization. Here we investigated the possible forces driving the assemblage of bacterial endophytic and rhizospheric communities, isolated from two congeneric medicinal plants, Echinacea purpurea (L.) Moench and Echinacea angustifolia (DC) Heller, grown in the same soil, by analyzing bacterial strains (isolated from three different compartments, i...
June 14, 2018: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29895490/what-s-in-the-box-authentication-of-echinacea-herbal-products-using-dna-metabarcoding-and-hptlc
#2
Ancuta Cristina Raclariu, Carmen Elena Ţebrencu, Mihael Cristin Ichim, Oana Teodora Ciupercǎ, Anne Krag Brysting, Hugo de Boer
BACKGROUND: Differences in regulatory policies between countries as well as a lack of appropriate standardized methods for the authentication and quality control of herbal products directly impact their quality and safety. Echinacea products are among the top-selling herbal products in Europe and the United States with indications for a broad range of ailments. The increased use of Echinacea species has led to concerns about adulterated products resulting from challenges in morphology-based identification, due to overlapping morphological variation, frequent hybridization between species, and deliberate adulteration...
May 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29783690/echinacoside-an-inestimable-natural-product-in-treatment-of-neurological-and-other-disorders
#3
REVIEW
Jingjing Liu, Lingling Yang, Yanhong Dong, Bo Zhang, Xueqin Ma
Echinacoside (ECH), a natural phenylethanoid glycoside, was first isolated from Echinacea angustifolia DC. (Compositae) sixty years ago. It was found to possess numerous pharmacologically beneficial activities for human health, especially the neuroprotective and cardiovascular effects. Although ECH showed promising potential for treatment of Parkinson's and Alzheimer's diseases, some important issues arose. These included the identification of active metabolites as having poor bioavailability in prototype form, the definite molecular signal pathways or targets of ECH with the above effects, and limited reliable clinical trials...
May 18, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29749084/echinacea-plants-as-antioxidant-and-antibacterial-agents-from-traditional-medicine-to-biotechnological-applications
#4
REVIEW
Mehdi Sharifi-Rad, Dima Mnayer, Maria Flaviana Bezerra Morais-Braga, Joara Nályda Pereira Carneiro, Camila Fonseca Bezerra, Henrique Douglas Melo Coutinho, Bahare Salehi, Miquel Martorell, María Del Mar Contreras, Azam Soltani-Nejad, Yoshie Adriana Hata Uribe, Zubaida Yousaf, Marcello Iriti, Javad Sharifi-Rad
The genus Echinacea consists of 11 taxa of herbaceous and perennial flowering plants. In particular, Echinacea purpurea (L.) Moench is widely cultivated all over the United States, Canada, and in Europe, exclusively in Germany, for its beauty and reported medicinal properties. Echinacea extracts have been used traditionally as wound healing to improve the immune system and to treat respiratory symptoms caused by bacterial infections. Echinacea extracts have demonstrated antioxidant and antimicrobial activities, and to be safe...
May 10, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29582619/oral-echinacea-exerts-complete-clearing-of-multiple-facial-molluscum-contagiosum-in-a-young-black-patient
#5
Annunziata Dattola, Alessandra Ventura, Mauro Mazzeo, Luca Bianchi
No abstract text is available yet for this article.
March 26, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29554408/alternative-therapies-for-chronic-rhinosinusitis-a-review
#6
Aaron S Griffin, Peter Cabot, Ben Wallwork, Ben Panizza
The use of alternative medicine in chronic rhinosinusitis (CRS) continues to increase in popularity, for the most part without meeting the burden of being based on sound clinical evidence. New and emerging treatments, both natural and developed, are numerous, and it remains a challenge for otolaryngologists as well as general practitioners to keep up to date with these therapies and their efficacy. In this systematic review, we discuss a number of alternative therapies for CRS, their proposed physiologic mechanisms, and evidence supporting their use...
March 2018: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29430971/insulin-like-3-expression-and-fibrosis-induction-after-intra-testicular-injection-of-magnetic-nanoparticles-in-rat-testis-and-the-ameliorative-role-of-echinacea-purpurea-extract
#7
A Awaad, M A Adly, D Hosny
The World Health Organization has approved magnetic nanoparticles (MNP) for use as a contrast agent for magnetic resonance imaging or tumor hyperthermia treatment. MNP are toxic over time after intra-testicular injection. A clear strategy to ameliorate the toxic side effects of MNP in normal tissues after medical application has not yet been developed. We used an extract of Echinacea purpurea (EP) as a natural source of antioxidant and free radical scavenging product for detoxification of MNP in testicular tissues...
February 12, 2018: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission
https://www.readbyqxmd.com/read/29215298/echinacea-purpurea-protects-against-restraint-stress-induced-immunosuppression-in-balb-c-mice
#8
Seonyoung Park, Mak-Soon Lee, Sunyoon Jung, Seohyun Lee, Oran Kwon, Matthias Heinrich Kreuter, Tania Perrinjaquet-Moccetti, Bokkee Min, Seong Ho Yun, Yangha Kim
Echinacea purpurea has been widely used for the prevention and treatment of upper respiratory tract infections and the common cold. The restraint stress has been reported to suppress a broad spectrum of immune functions. The aim of this study was to investigate the protective effects of the pressed juice of E. purpurea (L.) Moench (EFLA® 894; Echinacea) against restraint stress-induced immunosuppression in BALB/c mice. Echinacea significantly normalized the restraint stress-induced reduction in splenocyte proliferation and splenic natural killer (NK) cell activity (P < ...
March 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29208923/plant-endophytes-interaction-influences-the-secondary-metabolism-in-echinacea-purpurea-l-moench-an-in-vitro-model
#9
Valentina Maggini, Marinella De Leo, Alessio Mengoni, Eugenia Rosaria Gallo, Elisangela Miceli, Rose Vanessa Bandeira Reidel, Sauro Biffi, Luisa Pistelli, Renato Fani, Fabio Firenzuoli, Patrizia Bogani
The influence of the interaction(s) between the medicinal plant Echinacea purpurea (L.) Moench and its endophytic communities on the production of alkamides is investigated. To mimic the in vivo conditions, we have set up an infection model of axenic in vitro E. purpurea plants inoculated with a pool of bacterial strains isolated from the E. purpurea stems and leaves. Here we show different alkamide levels between control (not-inoculated) and inoculated plants, suggesting that the alkamide biosynthesis may be modulated by the bacterial infection...
December 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29196903/concurrent-use-of-prescription-drugs-and-herbal-medicinal-products-in-older-adults-a-systematic-review
#10
REVIEW
Taofikat B Agbabiaka, Barbara Wider, Leala K Watson, Claire Goodman
BACKGROUND: The use of herbal medicinal products (HMPs) is common among older adults; however, little is known about concurrent use with prescription drugs, as well as potential interactions associated with such combinations. OBJECTIVE: The aim of this systematic review was to identify and evaluate the literature on concurrent prescription and HMP use among older adults to assess prevalence, patterns, potential interactions and factors associated with this use. METHODS: Systematic searches were conducted in the MEDLINE, PsycINFO, EMBASE, CINAHL, AMED, Web of Science and Cochrane databases from inception to May 2017 for studies reporting concurrent use of prescription medicines with HMPs in adults ≥ 65 years of age...
December 2017: Drugs & Aging
https://www.readbyqxmd.com/read/29184939/consumption-of-plant-food-supplements-in-the-netherlands
#11
Suzanne M F Jeurissen, Elly J M Buurma-Rethans, Marja H Beukers, Martine Jansen-van der Vliet, Caroline T M van Rossum, R Corinne Sprong
The use of food supplements containing herbs or other botanical ingredients (plant food supplements, PFS) is on the rise. In some cases, PFS can contain compounds that are toxic and may pose a health risk. To assess the potential health risks, information on the consumption of PFS is required, however, this was lacking for the Netherlands. In the current study, the consumption of PFS was investigated for several subgroups in the Dutch population, including children. Data from the Dutch National Food Consumption Surveys were used to get a first impression on the consumption of PFS...
January 24, 2018: Food & Function
https://www.readbyqxmd.com/read/29184589/comparing-the-effect-of-echinacea-and-chlorhexidine-mouthwash-on-the-microbial-flora-of-intubated-patients-admitted-to-the-intensive-care-unit
#12
Mehdi Safarabadi, Ehsanollah Ghaznavi-Rad, Abdolghader Pakniyat, Korosh Rezaie, Ali Jadidi
Background: Providing intubated patients admitted to the intensive care units with oral healthcare is one of the main tasks of nurses in order to prevent Ventilator-Associated Pneumonia (VAP). This study aimed at comparing the effects of two mouthwash solutions (echinacea and chlorhexidine) on the oral microbial flora of patients hospitalized in the intensive care units. Materials and Methods: In this clinical trial, 70 patients aged between18 and 65 years undergoing tracheal intubation through the mouth in three hospitals in Arak, were selected using simple random sampling and were randomly divided into two groups: the intervention group and the control group...
November 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/29042288/mast-cell-degranulation-and-calcium-influx-are-inhibited-by-an-echinacea-purpurea-extract-and-the-alkylamide-dodeca-2e-4e-dienoic-acid-isobutylamide
#13
Travis V Gulledge, Nicholas M Collette, Emily Mackey, Stephanie E Johnstone, Yasamin Moazami, Daniel A Todd, Adam J Moeser, Joshua G Pierce, Nadja B Cech, Scott M Laster
ETHNOPHARMACOLOGICAL RELEVANCE: Native Americans used plants from the genus Echinacea to treat a variety of different inflammatory conditions including swollen gums, sore throats, skin inflammation, and gastrointestinal disorders. Today, various Echinacea spp. preparations are used primarily to treat upper respiratory infections. AIM OF THE STUDY: The goal of this study was to evaluate the effects of an ethanolic E. purpurea (L) Moench root extract and the alkylamide dodeca-2E,4E-dienoic acid isobutylamide (A15) on mast cells, which are important mediators of allergic and inflammatory responses...
February 15, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28990842/microrna-655-3p-regulates-echinacea-purpurea-mediated-activation-of-abcg2
#14
Charles Awortwe, Meike Kaehler, Bernd Rosenkranz, Ingolf Cascorbi, Henrike Bruckmueller
The aim of this study was to investigate the regulatory effect of Echinacea purpurea (EP) on efflux transporters ABCB1 and ABCG2 and to identify specific microRNAs contributing to their post-transcriptional regulation. ABCB1 and ABCG2 levels were assessed in human hepatoblastoma HepG2 cells treated with 50 µg/mL methanolic extract of commercial EP capsules for different durations of time. The microRNA expression profile of HepG2 cells after EP treatment was evaluated and in silico target prediction was subsequently conducted to identify specific microRNAs with binding sites in the 3'-UTR of ABCB1 and ABCG2...
October 9, 2017: Xenobiotica; the Fate of Foreign Compounds in Biological Systems
https://www.readbyqxmd.com/read/28979329/synthesis-of-titanium-dioxide-nanoparticles-using-echinacea-purpurea-herba
#15
Renata Dobrucka
Nowadays green synthesis of metal nanoparticles is a developing area of research. In this study, titanium dioxide nanoparticles were biosynthesized using an aqueous solution of Echinacea purpurea herba extract as a bioreductant. This is novel and interesting method for synthesis of TiO2 nanoparticles. The prepared titanium dioxide nanoparticles were characterized using ultraviolet-visible spectroscopy (UV-VIS), transmission electron microscopy (SEM), total reflection X-Ray fluorescence analysis (TXRF) and Fourier-transform infrared spectroscopy (FTIR)...
2017: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/28880243/simultaneous-determination-of-seven-phenolic-acids-in-rat-plasma-using-uhplc-esi-ms-ms-after-oral-administration-of-echinacea-purpurea-extract
#16
Yan Du, Zhibin Wang, Libo Wang, Mingjie Gao, Liqian Wang, Chunli Gan, Chunjuan Yang
A rapid and sensitive Ultra High Performance Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry (UHPLC-ESI-MS/MS) method was developed and validated to simultaneously determine the concentration of seven phenolic acids (syringic acid, ferulic acid, caffeic acid, vanillic acid, p-coumaric acid, 3,4-dihydroxybenzoic acid and 4-hydroxybenzoic acid) in rat plasma after oral administration of Echinacea purpurea extract. After mixing with the internal standard (IS), butylparaben, plasma samples were prepared by liquid-liquid extraction with ethyl acetate...
September 7, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28861641/medicinal-plant-extracts-modulate-respiratory-burst-and-proliferation-activity-of-rainbow-trout-oncorhynchus-mykiss-leukocytes
#17
Chiara Bulfon, Marco Galeotti, Donatella Volpatti
The present study was designed to investigate the immunomodulatory effects of Aloe vera, Curcuma longa, Echinacea purpurea, Lavandula officinalis, Origanum vulgare, Panax ginseng, and Rheum officinale extracts on leukocytes purified from rainbow trout (Oncorhynchus mykiss) head kidney. The cells were cultured in a medium containing increasing doses of extracts; afterwards, they were tested for reactive oxygen species production after stimulation with phorbol myristate acetate (PMA) and proliferation in the presence or absence of phytohemagglutinin from Phaseolus vulgaris (PHA-P)...
February 2018: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/28846157/allergy-like-immediate-reactions-with-herbal-medicines-in-children-a-retrospective-study-using-data-from-vigibase-%C3%A2
#18
MULTICENTER STUDY
Ricarda Meincke, Jitka Pokladnikova, Julie Straznicka, Ronald H B Meyboom, David Niedrig, Stefan Russmann, Ludek Jahodar
BACKGROUND: The use of herbal medicines in children and the general population is continually on the rise with an overall herbal lifetime and current use ranging between 0.8%-85.5% and 2.2%-8.9%, respectively. Although acute hypersensitivity reactions are generally considered to be rare, little knowledge exists on the frequency and type of these reactions especially in specific populations like children. OBJECTIVES: To assess the patterns of acute hypersensitivity reactions to herbal medicines reported to the WHO global individual case safety report (ICSR) database VigiBase® in children...
November 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28841426/a-new-method-based-on-supercritical-fluid-extraction-for-polyacetylenes-and-polyenes-from-echinacea-pallida-nutt-nutt-roots
#19
Massimo Tacchini, Antonella Spagnoletti, Virginia Brighenti, Francesco Pio Prencipe, Stefania Benvenuti, Gianni Sacchetti, Federica Pellati
The genus Echinacea (Asteraceae) includes species traditionally used in phytotherapy. Among them, Echinacea pallida (Nutt.) Nutt. root extracts are characterized by a representative antiproliferative activity, due to the presence of acetylenic compounds. In this study, supercritical fluid extraction (SFE) was applied and compared with conventional Soxhlet extraction (SE) in order to obtain a bioactive extract highly rich in polyacetylenes and polyenes from E. pallida roots. The composition of the extracts was monitored by means of HPLC-UV/DAD and HPLC-ESI-MS(n) by using an Ascentis Express C18 column (150mm×3...
August 12, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28797065/a-systematic-review-of-the-pharmacokinetic-and-pharmacodynamic-interactions-of-herbal-medicine-with-warfarin
#20
REVIEW
Songie Choi, Dal-Seok Oh, Ui Min Jerng
OBJECTIVES: The aim of this study was to systematically review data regarding pharmacokinetic (PK)-pharmacodynamic (PD) parameters from randomized controlled trials relating to interactions between herbal medicines and warfarin. METHODS: Three electronic databases were searched to identify relevant trials. Two reviewers independently performed the study selection and data extraction. The risk of bias and reporting quality were also assessed independently by two reviewers using the Cochrane risk of bias tool and the consolidated standards of reporting trials (CONSORT)...
2017: PloS One
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