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https://www.readbyqxmd.com/read/30119087/integrated-rehabilitation-for-breast-cancer-survivors
#1
Andrea L Cheville, Sarah A McLaughlin, Tufia Haddad, Kathleen D Lyons, Robin Newman, Kathryn J Ruddy
The physical and psychological side effects of breast cancer therapies can have substantial impact on survivors' physical and social functioning. Roughly half of the more than 3 million Americans alive with a history of breast cancer report adverse, function-degrading sequelae related to their oncologic treatments. Care delivery models for the timely delivery of rehabilitation services have been proposed yet limitedly vetted or implemented. These include the prospective surveillance model, procedure-linked referrals, survivorship care plans and risk stratification...
August 16, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/30118823/the-opioid-system-in-stress-induced-memory-disorders-from-basic-mechanisms-to-clinical-implications-in-posttraumatic-stress-disorder-and-alzheimer-s-disease
#2
REVIEW
Angélica Torres-Berrio, Mauricio O Nava-Mesa
Cognitive and emotional impairment are a serious consequence of stress exposure and are core features of neurological and psychiatric conditions that involve memory disorders. Indeed, acute and chronic stress are high-risk factors for the onset of posttraumatic stress disorder (PTSD) and Alzheimer's disease (AD), two devastating brain disorders associated with memory dysfunction. Besides the sympathetic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis, stress response also involves the activation of the opioid system in brain regions associated with stress regulation and memory processing...
August 14, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/30117784/comparing-in-the-moment-skill-coaching-effects-from-tailored-versus-non-tailored-acceptance-and-commitment-therapy-mobile-apps-in-a-non-clinical-sample
#3
Michael E Levin, Cynthia Navarro, Rick A Cruz, Jack Haeger
Mobile apps are promising for teaching how to practice psychological skills in high-risk and in vivo momentary situations, but there has been minimal research on the immediate effects of app-based skill coaching on mental health in-the-moment. This study analyzed the mobile app data in a non-clinical sample of 39 adults participating in a larger randomized controlled trial, with participants randomized to an acceptance and commitment therapy (ACT) mobile app that tailors skill coaching based on in-the-moment variables (n = 17) or an app that provides randomly selected skill coaching (n = 22)...
August 17, 2018: Cognitive Behaviour Therapy
https://www.readbyqxmd.com/read/30116180/olfactory-memory-impairment-differs-by-sex-in-a-rodent-model-of-pediatric-radiotherapy
#4
Emma C Perez, Shaefali P Rodgers, Taeko Inoue, Steen E Pedersen, J Leigh Leasure, M Waleed Gaber
Although an effective treatment for pediatric brain tumors, cranial radiation therapy (CRT) damages surrounding healthy tissue, thereby disrupting brain development. Animal models of pediatric CRT have primarily relied on visual tasks to assess cognitive impairment. Moreover, there has been a lack of sex comparisons as most research on the cognitive effects of pediatric CRT does not include females. Therefore, we utilized olfaction, an ethologically relevant sensory modality, to assess cognitive impairment in an animal model of CRT that included both male and female mice...
2018: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/30115082/music-meets-robotics-a-prospective-randomized-study-on-motivation-during-robot-aided-therapy
#5
Kilian Baur, Florina Speth, Aniket Nagle, Robert Riener, Verena Klamroth-Marganska
BACKGROUND: Robots have been successfully applied in motor training during neurorehabilitation. As music is known to improve motor function and motivation in neurorehabilitation training, we aimed at integrating music creation into robotic-assisted motor therapy. We developed a virtual game-like environment with music for the arm therapy robot ARMin, containing four different motion training conditions: a condition promoting creativity (C+) and one not promoting creativity (C-), each in a condition with (V+) and without (V-) a visual display (i...
August 16, 2018: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/30108004/cognitive-and-adaptive-outcomes-after-proton-radiation-for-pediatric-patients-with-brain-tumors
#6
Margaret B Pulsifer, Haley Duncanson, Julie Grieco, Casey Evans, Irene Delgado Tseretopoulos, Shannon MacDonald, Nancy J Tarbell, Torunn I Yock
PURPOSE: Radiation therapy is integral in treatment of pediatric brain tumors, but it is associated with negative long-term sequelae. Proton beam radiation therapy (PRT), which enables better focusing of radiation on tumors, may entail fewer sequelae. This prospective study examined cognitive and adaptive functioning in children and young adults treated with PRT. METHODS AND MATERIALS: A total of 155 patients were assessed using age-appropriate measures for cognitive and adaptive functioning at start of or during PRT (baseline) and at follow-up...
June 6, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/30105155/identifying-priority-outcomes-that-influence-selection-of-disease-modifying-therapies-in-ms
#7
Gregory S Day, Alexander Rae-Grant, Melissa J Armstrong, Tamara Pringsheim, Stacey S Cofield, Ruth Ann Marrie
Background: Persons with multiple sclerosis (MS) may now choose from a broad array of approved disease-modifying treatments (DMTs). The priority that patients and practitioners assign to specific clinical outcomes is likely to influence the MS DMT selection process. Methods: We invited 9,126 participants in the North American Research Committee on Multiple Sclerosis (NARCOMS) Registry and 18 members of the American Academy of Neurology MS DMT guideline development panel to complete a brief survey prioritizing outcomes of importance to MS DMT selection...
June 2018: Neurology. Clinical Practice
https://www.readbyqxmd.com/read/30104727/network-changes-associated-with-transdiagnostic-depressive-symptom-improvement-following-cognitive-behavioral-therapy-in-mdd-and-ptsd
#8
Zhen Yang, Shi Gu, Nicolas Honnorat, Kristin A Linn, Russell T Shinohara, Irem Aselcioglu, Steven Bruce, Desmond J Oathes, Christos Davatzikos, Theodore D Satterthwaite, Danielle S Bassett, Yvette I Sheline
Despite widespread use of cognitive behavioral therapy (CBT) in clinical practice, its mechanisms with respect to brain networks remain sparsely described. In this study, we applied tools from graph theory and network science to better understand the transdiagnostic neural mechanisms of this treatment for depression. A sample of 64 subjects was included in a study of network dynamics: 33 patients (15 MDD, 18 PTSD) received longitudinal fMRI resting state scans before and after 12 weeks of CBT. Depression severity was rated on the Montgomery-Asberg Depression Rating Scale (MADRS)...
August 13, 2018: Molecular Psychiatry
https://www.readbyqxmd.com/read/30096261/heart-transplant-recipients-prefer-a-telemental-health-cognitive-behavioral-therapy-intervention-delivered-by-telephone
#9
Flavio Rose Epstein, Chi-Mei Liu, Janet Marie Stevenson
BACKGROUND: Depression and anxiety are common after heart transplant, and in a regional heart transplant center servicing northern California, willingness to participate in treatment can be a major barrier. INTRODUCTION: Our primary aim is to design a remote cognitive-behavioral therapy (CBT) intervention. This study is the first step in the process. Through a survey to the cohort of heart transplant recipients (N = 230), managed within the Kaiser Permanente Northern California's Heart Transplant Service, we aimed to assess symptoms of stress, depression, and anxiety, patient willingness to participate in a CBT intervention, and preference between video and telephone...
August 10, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/30094159/aberrant-oscillatory-dynamics-during-somatosensory-processing-in-hiv-infected-adults
#10
Rachel K Spooner, Alex I Wiesman, Mackenzie S Mills, Jennifer O'Neill, Kevin R Robertson, Howard S Fox, Susan Swindells, Tony W Wilson
While the arrival of combination antiretroviral therapy significantly decreased the prevalence of HIV-associated dementia, between 35 and 70% of all infected adults continue to develop some form of cognitive impairment. These deficits appears to affect multiple neural subsystems, but the mechanisms and extent of damage are not fully understood. In the current study, we utilized magnetoencephalography (MEG), advanced oscillatory analysis methods, and a paired-pulse somatosensory stimulation paradigm to interrogate pre-attentive inhibitory processing in 43 HIV-infected adults and 28 demographically-matched uninfected controls...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/30093853/immune-and-neuroprotective-effects-of-physical-activity-on-the-brain-in-depression
#11
REVIEW
Cristy Phillips, Atoossa Fahimi
Physical activity-a lifestyle factor that is associated with immune function, neuroprotection, and energy metabolism-modulates the cellular and molecular processes in the brain that are vital for emotional and cognitive health, collective mechanisms that can go awry in depression. Physical activity optimizes the stress response, neurotransmitter level and function (e.g., serotonergic, noradrenergic, dopaminergic, and glutamatergic), myokine production (e.g., interleukin-6), transcription factor levels and correlates [e...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/30087091/web-based-cognitive-bias-intervention-for-psychiatric-disorders-protocol-for-a-systematic-review
#12
Melvyn Zhang, Jiangbo Ying, Guo Song, Daniel Ss Fung, Helen Smith
BACKGROUND: Traditional psychological therapies focus mainly on modification of individuals' conscious decision-making process. Unconscious processes, such as cognitive biases, have been found accountable for various psychiatric psychopathologies, and advances in technologies have transformed how bias modification programs are being delivered. OBJECTIVE: The primary aim of this review is to synthesize evidence of Web-based cognitive bias modification intervention for bias reduction...
August 7, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/30086659/the-effect-of-group-based-cognitive-behavioral-therapy-on-inflammatory-biomarkers-in-patients-with-coronary-heart-disease-results-from-the-suprim-trial
#13
Erik M G Olsson, Fredrika Norlund, Ronnie Pingel, Gunilla Burell, Mats Gulliksson, Anders Larsson, Bo Karlsson, Kurt Svärdsudd, Claes Held
BACKGROUND: The Secondary Prevention in Uppsala Primary Healthcare Project (SUPRIM) is a prospective randomized controlled trial of a group-based cognitive behavioral therapy (CBT) stress management program for coronary heart disease (CHD) patients. The intervention reduced the risk of fatal or non-fatal first recurrent cardiovascular (CV) events. The aim of the present study was to analyze if the positive effects of the CBT program on clinical outcomes could have been mediated by changes in biomarkers for inflammation...
August 8, 2018: Upsala Journal of Medical Sciences
https://www.readbyqxmd.com/read/30086469/mindfulness-based-cognitive-therapy-for-bipolar-disorder-a-systematic-review
#14
REVIEW
David A Lovas, Zev Schuman-Olivier
BACKGROUND: Persisting high levels of relapse, morbidity and mortality in bipolar disorder (BD) in spite of first-line, evidence-based psychopharmacology has spurred development and research on adjunctive psychotherapies. Mindfulness-based cognitive therapy (MBCT) is an emerging psychotherapy that has shown benefit in related and comorbid conditions such as major depressive, anxiety, and substance disorders. Furthermore, neurocognitive studies of MBCT suggest that it may have effects on some of the theorized pathophysiological processes in BD...
July 6, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/30078503/chronic-pain-in-refugees-with-posttraumatic-stress-disorder-ptsd-a-systematic-review-on-patients-characteristics-and-specific-interventions
#15
REVIEW
C Rometsch-Ogioun El Sount, P Windthorst, J Denkinger, K Ziser, C Nikendei, D Kindermann, J Ringwald, V Renner, S Zipfel, F Junne
OBJECTIVE: Chronic pain in patients with posttraumatic stress disorder (PTSD) is a frequent symptom and a complicating factor in the treatment of patients. The study' purpose is to systematically review the scientific literature on patients' characteristics and the effects of specific interventions implemented for the treatment of chronic pain in traumatized refugees. METHOD: A systematic search of the current literature was conducted in PubMed and Web of Science, from 1996 to 2017...
July 30, 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/30075313/risk-factors-for-relapse-and-recurrence-of-depression-in-adults-and-how-they-operate-a-four-phase-systematic-review-and-meta-synthesis
#16
REVIEW
J E J Buckman, A Underwood, K Clarke, R Saunders, S D Hollon, P Fearon, S Pilling
PURPOSE: To review and synthesise prognostic indices that predict subsequent risk, prescriptive indices that moderate treatment response, and mechanisms that underlie each with respect to relapse and recurrence of depression in adults. RESULTS AND CONCLUSIONS: Childhood maltreatment, post-treatment residual symptoms, and a history of recurrence emerged as strong prognostic indicators of risk and each could be used prescriptively to indicate who benefits most from continued or prophylactic treatment...
July 29, 2018: Clinical Psychology Review
https://www.readbyqxmd.com/read/30065621/investigation-on-the-neural-mechanism-of-hypnosis-based-respiratory-control-using-functional-mri
#17
Yanjun Liu, Wenjian Qin, Rongmao Li, Shaode Yu, Yini He, Yaoqin Xie
Respiratory control is essential for treatment effect of radiotherapy due to the high dose, especially for thoracic-abdomen tumor, such as lung and liver tumors. As a noninvasive and comfortable way of respiratory control, hypnosis has been proven effective as a psychological technology in clinical therapy. In this study, the neural control mechanism of hypnosis for respiration was investigated by using functional magnetic resonance imaging (fMRI). Altered spontaneous brain activity as well as neural correlation of respiratory motion was detected for eight healthy subjects in normal state (NS) and hypnosis state (HS) guided by a hypnotist...
2018: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/30061195/patients-perspectives-on-gp-interactions-after-cognitive-behavioural-therapy-for-refractory-ibs-a-qualitative-study-in-uk-primary-and-secondary-care
#18
Alice Sibelli, Rona Moss-Morris, Trudie Chalder, Felicity L Bishop, Sula Windgassen, Hazel Everitt
BACKGROUND: Previous studies have identified issues with the doctor-patient relationship in irritable bowel syndrome (IBS) that negatively impact symptom management. Despite this, little research has explored interactions between GPs and patients with refractory IBS. National guidelines suggest cognitive behavioural therapy (CBT) as a treatment option for refractory symptoms. AIM: To explore perceptions of interactions with GPs in individuals with refractory IBS after receiving CBT for IBS or treatment as usual (TAU)...
July 30, 2018: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/30059900/why-do-people-living-with-hiv-not-initiate-treatment-a-systematic-review-of-qualitative-evidence-from-low-and-middle-income-countries
#19
Shahira Ahmed, Jessica Autrey, Ingrid T Katz, Matthew P Fox, Sydney Rosen, Dorina Onoya, Till Bärnighausen, Kenneth H Mayer, Jacob Bor
BACKGROUND: Many people living with HIV (PLWH) who are eligible for antiretroviral therapy (ART) do not initiate treatment, leading to excess morbidity, mortality, and viral transmission. As countries move to treat all PLWH at diagnosis, it is critical to understand reasons for non-initiation. METHODS: We conducted a systematic review of the qualitative literature on reasons for ART non-initiation in low- and middle-income countries. We screened 1376 titles, 680 abstracts, and 154 full-text reports of English-language qualitative studies published January 2000-April 2017; 20 met criteria for inclusion...
May 30, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/30059565/the-improvement-of-memory-deficits-after-whole-body-cryotherapy-the-first-report
#20
J Rymaszewska, K M Urbanska, D Szczesniak, B Stanczykiewicz, E Trypka, A Zablocka
BACKGROUND: Mild Cognitive Impairments (MCI) and dementia are still incurable. The Whole-Body Cryotherapy (WBC) - short, cyclic exposure to extremely low temperatures - has proven anti-inflammatory and anti-oxidative effects. It can also induce hormonal, lipid and neural changes. OBJECTIVE: To evaluate the WBC effect on cognitive functioning and blood parameters of MCI patients. MATERIALS AND METHODS: Participants with MCI undertook 10 WBC sessions...
May 2018: Cryo Letters
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