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https://www.readbyqxmd.com/read/30324812/migration-of-a-fractured-ring-iud-resulting-in-vesicovaginal-fistula-and-vaginal-calculus
#1
Dewen Yan, Zhan Shi, Liping Wang, Xiumin Zhao
CASE: Although many complications have been reported with intrauterine contraceptive devices (IUDs), vesicovaginal fistula with secondary vaginal stones is rare. We report the case of a 46-year-old woman who presented with a vaginal discharge lasting 2 months. Two years previously, she had undergone cystoscopic lithotripsy and surgery to remove an IUD, after pelvic radiography had revealed a fractured Chinese stainless steel ring IUD with secondary vesical stones that had been the cause of her urinary tract symptoms...
October 16, 2018: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/30323939/guillain-barr%C3%A3-syndrome-associated-with-bladder-instillation-of-bacille-calmette-gu%C3%A3-rin-bcg
#2
Karmel Webb, Pradhib Venkatesan
Introduction: Guillain Barré Syndrome (GBS) has rarely been associated with tuberculosis and has been previously reported after Bacille Calmette Guérin (BCG) vaccination, but we report an association of GBS with intra-vesical BCG instillations followed by the clinical picture of disseminated BCGosis. Case presentation: A 68-year-old man with bladder carcinoma had a transurethral tumour resection followed by repeated BCG instillations. Catheterization for his eighth dose was traumatic, causing frank haematuria...
August 2018: JMM Case Reports
https://www.readbyqxmd.com/read/30311992/development-of-a-robotic-kidney-transplantation-program-from-deceased-donors-in-a-referral-academic-centre-technical-nuances-and-preliminary-results
#3
Graziano Vignolini, Riccardo Campi, Francesco Sessa, Isabella Greco, Aida Larti, Saverio Giancane, Arcangelo Sebastianelli, Mauro Gacci, Adriano Peris, Vincenzo Li Marzi, Alberto Breda, Giampaolo Siena, Sergio Serni
OBJECTIVE: To report the development of the first robot-assisted kidney transplantation (RAKT) program from deceased donors examining technical feasibility and early perioperative and functional outcomes at a referral academic Centre. PATIENTS AND METHODS: A robotic kidney transplantation program was developed in 2016 at our Institution following a structured modular training. Specific inclusion/exclusion criteria for both living and deceased donors were set. Data from patients undergoing RAKT from January 2017 to April 2018 were prospectively collected in an a priori developed web-based dataset...
October 12, 2018: BJU International
https://www.readbyqxmd.com/read/30284731/micronuclei-frequency-in-urothelial-cells-of-bladder-cancer-patients-as-a-biomarker-of-prognosis
#4
Felicidad Espinoza, Lluis Cecchini, Juan Morote, Ricard Marcos, Susana Pastor
It has been suggested that the frequency of micronuclei (MN) in defoliated urothelial cells could be used as a biomarker for both the potential risk of bladder cancer (BC) and its progression. To prove this we have carried out a large study evaluating the MN frequency in a group of 383 hospital patients submitted to cystoscopy. From them, 77 were negative in their first cystoscopy, and were considered as a reference group; 79 were positive and were classified as patients with tumor; and 227 with previous bladder cancer submitted to follow-up monitoring were negative and classified as BC patients without tumor...
October 4, 2018: Environmental and Molecular Mutagenesis
https://www.readbyqxmd.com/read/30272477/suspected-carboplatin-extravasation-reactions-in-seven-dogs
#5
Kristina Bowles Miller, Amandine Lejeune, Rebecca Regan, Anna Szivek, Kevin Kow
Carboplatin is a platinum chemotherapeutic agent commonly used in veterinary oncology that is currently classified as an irritant to local tissues when extravasated. To the authors' knowledge, there are no reports of vesicant injuries associated with carboplatin administration reported in the veterinary literature. In this case series, seven dogs are described to have experienced injuries following a suspected carboplatin extravasation resembling vesicant injuries a median of 7 days after carboplatin administration (range 4-15 days)...
October 1, 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/30267094/an-engineered-human-fibroblast-growth-factor-1-derivative-tthx1114-ameliorates-short-term-corneal-nitrogen-mustard-injury-in-rabbit-organ-cultures
#6
David D Eveleth, Jennifer J Eveleth, Amuthakannan Subramaniam, Rita Hahn, Peihong Zhou, Marion K Gordon, Ralph A Bradshaw
Purpose: Organ cultures of rabbit corneas have been used to ascertain the effectiveness of a human fibroblast growth factor (FGF)-1 derivative (TTHX1114), lacking cysteine residues, to protect against and/or repair epithelial lesions following exposure to nitrogen mustard (NM). Methods: Rabbit corneas were exposed to NM and cultured for up to 14 days, with or without drug (TTHX1114). At specified times, tissue was examined by histopathology and graded by a novel composite scale...
September 4, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/30258511/zinner-syndrome-presenting-with-intermittent-scrotal-pain-in-a-young-man
#7
Sofia Florim, Vitor Oliveira, Diogo Rocha
Congenital malformations of the seminal vesicle are uncommon, and most of them are cystic malformations. If an insult occurs during the first trimester of gestation, the embryogenesis of the kidney, ureter, seminal vesicle, and vas deferens could be altered. The mutual embryological origins of the seminal vesicle and ureteral bud from the mesonephric (Wolffian) duct result in association between ipsilateral renal agenesis and seminal vesical cysts. Zinner syndrome is a rare condition comprising a triad of unilateral renal agenesis, ipsilateral seminal vesicle obstruction and ipsilateral ejaculatory duct obstruction...
December 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/30257109/ebselen-oxide-attenuates-mechlorethamine-dermatotoxicity-in-the-mouse-ear-vesicant-model
#8
Hemanta C Rao Tumu, Benedette J Cuffari, Maria A Pino, Jerzy Palus, Magdalena Piętka-Ottlik, Blase Billack
Mechlorethamine (HN2) is an alkylating agent and sulfur mustard mimetic. Topical exposure to HN2 is associated with tissue blistering. Previous work in our laboratory has shown that ebselen (EB-1) possesses anti-vesicant, anti-inflammatory, anti-bacterial, anti-fungal, and cytoprotective properties, both in vivo and in vitro. We recently reported that ebselen oxide (EB-2), an analog of EB-1 with a tetravalent selenium atom, also possesses anti-bacterial and anti-fungal activity and confers cytoprotection against HN2 in vitro...
September 26, 2018: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/30220977/a-patient-derived-orthotopic-xenograft-model-enabling-human-high-grade-urothelial-cell-carcinoma-of-the-bladder-tumor-implantation-growth-angiogenesis-and-metastasis
#9
Jessie Gills, Ravan Moret, Xin Zhang, John Nelson, Grace Maresh, Linh Hellmers, Daniel Canter, M'Liss Hudson, Shams Halat, Marc Matrana, Michael P Marino, Jakob Reiser, Maureen Shuh, Eric Laborde, Maria Latsis, Sunil Talwar, Stephen Bardot, Li Li
High-grade urothelial cell carcinoma of the bladder has a poor prognosis when lymph nodes are involved. Despite curative therapy for clinically-localized disease, over half of the muscle-invasive urothelial cell carcinoma patients will develop metastases and die within 5 years. There are currently no described xenograft models that consistently mimic urothelial cell carcinoma metastasis. To develop a patient-derived orthotopic xenograft model to mimic clinical urothelial cell carcinoma progression to metastatic disease, the urothelial cell carcinoma cell line UM-UC-3 and two urothelial cell carcinoma patient specimens were doubly tagged with Luciferase/RFP and were intra-vesically (IB) instilled into NOD/SCID mice with or without lymph node stromal cells (HK cells)...
August 24, 2018: Oncotarget
https://www.readbyqxmd.com/read/30219934/suprapubic-single-port-approach-for-complicated-diverticulitis
#10
A Spinelli, F Di Candido, M Carvello
BACKGROUND: Laparoscopic sigmoidectomy is the gold standard for elective surgical treatment of diverticulitis. A periumbilical single-port technique reduces the size of the access wound, usually to 3-4 cm. However, in the presence of large phlegmon or fistulae, the risk of conversion is higher and the extraction site might be enlarged. A suprapubic Pfannenstiel incision reduces the risk of incisional hernia compared to umbilical access and might provide the possibility to perform sigmoidectomy with a hybrid technique...
September 15, 2018: Techniques in Coloproctology
https://www.readbyqxmd.com/read/30195846/grade-groups-provides-improved-predictions-of-pathologic-and-early-oncologic-outcomes-compared-with-gleason-score-risk-groups
#11
Samer Kirmiz, Ji Qi, Stephen K Babitz, Susan Linsell, Brian Denton, Karandeep Singh, Gregory Auffenberg, James E Montie, Brian R Lane
PURPOSE: The grade grouping (GG) system was introduced in 2013. Data from academic centers suggests GG better distinguishes between prostate cancer risk groups than the Gleason score (GS) risk groups. We compared the performance of both for predicting pathological/recurrence outcomes using data from Michigan Urological Surgery Improvement Collaborative (MUSIC). MATERIALS AND METHODS: Patients undergoing biopsy and radical prostatectomy (RP) within MUSIC (3/2012-6/2017) were classified according to GG and GS...
September 6, 2018: Journal of Urology
https://www.readbyqxmd.com/read/30182258/oxidative-stress-and-neuroinflammation-should-be-both-considered-in-the-occurrence-of-fatigue-and-depression-in-multiple-sclerosis
#12
Vesic Katarina, Toncev Gordana, Miletic Drakulic Svetlana, Borovcanin Milica
Oxidative stress and neuroinflammation have a role in the pathogenesis of multiple sclerosis (MS) and in depression. Fatigue is the most disabling symptom in patients with MS and could also be a part of depressive symptomatology. In this study, we measured the serum levels of uric acid (UA) as a marker of oxidative stress and C-reactive protein (CRP) as an inflammatory marker, in 98 patients with MS in relapse and remitting phase of illness and 35 healthy subjects. Degree of depressive symptomatology and fatigue were assessed with Beck's Depression Inventory (BDI) and Fatigue Severity Scale (FSS)...
September 4, 2018: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/30175709/treatment-of-extravasation-injuries-in-infants-and-young-children-a-scoping-review-and-survey
#13
Mark Corbett, David Marshall, Melissa Harden, Sam Oddie, Robert Phillips, William McGuire
BACKGROUND: Extravasation injuries are caused by unintended leakages of fluids or medicines from intravenous lines, but there is no consensus on the best treatment approaches. OBJECTIVES: To identify which treatments may be best for treating extravasation injuries in infants and young children. DESIGN: Scoping review and survey of practice. POPULATION: Children aged < 18 years with extravasation injuries and NHS staff who treat children with extravasation injuries...
August 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/30170086/granular-cell-tumor-of-the-bladder-a-report-of-six-cases
#14
Yue Sun, Victor E Reuter, Cristina Magi-Galluzzi, Alex Sankin, Jonathan I Epstein
OBJECTIVE: To better characterize granular cell tumor of the bladder, with only 20 cases reported to date and unclear management guidelines. METHODS: We report five benign and one malignant granular cell tumor of the bladder. RESULTS: Patients were in the age range of 33 to 73 years. The size of tumor ranged from 0.2 to 6.3cm. Two benign granular cell tumors were incidental findings with others presenting with painless hematuria. Benign granular cell tumors infiltrated the muscularis propria and were confirmed by immunohistochemistry for S100 protein with negative stains for keratins...
August 29, 2018: Urology
https://www.readbyqxmd.com/read/30167990/laparoscopic-treatment-of-intestinal-obstruction-due-to-a-vitelline-vascular-remnant-and-simultaneous-appendicitis-a-case-report
#15
Kenjiro Date, Taro Yokota, Naoki Maehara
BACKGROUND: The presence of a vitelline vascular remnant is rare, and definitive preoperative diagnosis is difficult. We herein describe a case of intestinal obstruction caused by a vitelline vascular remnant with mild chronic appendicitis successfully diagnosed and treated with laparoscopic surgery. CASE PRESENTATION: A 14-year-old male was admitted to our hospital with sudden-onset right lower abdominal pain and vomiting. A blood test on admission revealed slight leukocytosis...
August 30, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/30167057/acute-urinary-retention-due-to-benign-prostatic-hyperplasia-associated-with-cystitis-glandularis-in-a-22-year-old-patient
#16
Skander Zouari, Khaireddine Bouassida, Khaled Ben Ahmed, Ahlem Bdioui Thabet, Mohamed Amine Krichene, Chawki Jebali
A 22-year-old man has consulted in emergency for acute urinary retention and left renal colic. Bladder catheterization was performed. Symptomatic treatment was provided with no improvement. MRI showed a pseudotumoral bladder wall thickening associated with vesical floor budding with prostate median lobe infiltration. The patient got an endoscopy that concluded to an inflammatory aspect of the bladder mycosa and a solid mass in the bladder neck arising. The biopsy during examination concluded to a glandular cystitis...
2018: Pan African Medical Journal
https://www.readbyqxmd.com/read/30113758/current-management-of-radiation-cystitis-a-review-and-practical-guide-to-clinical-management
#17
REVIEW
Claire Pascoe, Catriona Duncan, Benjamin W Lamb, Niall F Davis, Thomas H Lynch, Declan G Murphy, Nathan Lawrentschuk
Haemorrhage is a frequent complication of radiation cystitis leading to emergency presentations in patients with prior pelvic radiation therapy. Standard initial patient management strategies involve resuscitation, bladder washout with clot evacuation and continuous bladder irrigation. Beyond this, definitive surgical treatment is associated with significant morbidity and mortality. Alternative less invasive management options for non-emergent haemorrhagic cystitis include systemic medical therapies, hyperbaric oxygen, intra-vesical therapies and laser ablation...
August 16, 2018: BJU International
https://www.readbyqxmd.com/read/30110353/automated-quantification-of-low-amplitude-rhythmic-contractions-larc-during-real-world-urodynamics-identifies-a-potential-detrusor-overactivity-subgroup
#18
Zachary E Cullingsworth, Brooks B Kelly, Nicholas A Deebel, Andrew F Colhoun, Anna S Nagle, Adam P Klausner, John E Speich
OBJECTIVES: Detrusor overactivity (DO) is characterized by non-voiding detrusor smooth muscle contractions during the bladder filling phase and often contributes to overactive bladder. In some patients DO is observed as isolated or sporadic contractions, while in others DO is manifested as low amplitude rhythmic contractions (LARC). The aim of this study was to develop an objective method to quantify LARC frequencies and amplitudes in urodynamic studies (UDS) and identify a subgroup DO of patients with LARC...
2018: PloS One
https://www.readbyqxmd.com/read/30105456/shock-wave-lithotripsy-versus-endoscopic-cystolitholapaxy-in-the-management-of-patients-presenting-with-calcular-acute-urinary-retention-a-randomised-controlled-trial
#19
Mohamed Ali, Abdelwahab Hashem, Tamer E Helmy, Tamer Zewin, Khaled Z Sheir, Ahmed A Shokeir
PURPOSE: Shock wave lithotripsy (SWL) in treatment of bladder and urethral stones was not precisely determined. The objective of this study is to compare the efficacy and safety of SWL versus visual cystolitholapaxy in the management of calcular acute urine retention. METHODS: From March 2015 to February 2017, a randomised controlled study was conducted on 100 patients for whom urethral catheter fixed for acute retention of urine due to urethral or vesical radio-opaque stone(s) ≤ 2 cm...
August 13, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/30077537/giant-ureteric-calculus-in-a-patient-with-bladder-exstrophy
#20
Surya Prakash Vaddi, Seshu Mohan R, Satish Reddy
We report a case of giant ureteric calculus in an adult male with bladder exstrophy who presented with urinary incontinence and recurrent urinary tract infection. Investigations revealed a 16-cm ureteric calculus, a vesical calculus and a left staghorn renal calculus. Ureteric stone was removed by open ureterolithotomy.
August 2, 2018: Urology
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