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Nils Hansson
PURPOSE: This paper provides for the first time an overview of orthopaedic surgeons nominated for the Nobel Prize in physiology or medicine during the first six decades of the twentieth century. The study is part of the project "Enacting Excellency: Nobel Prize nominations for surgeons 1901-1960". METHODS: The nomination letters were gathered in the archive of the Nobel Committee at the Karolinska Institute in Solna, Sweden. RESULTS: Among the nominees, we find renowned scholars like Pierre Delbet, Themistocles Gluck, Gerhard Küntscher, Adolf Lorenz, Friedrich Pauwels, Leslie Rush, and Marius Smith-Petersen...
August 10, 2018: International Orthopaedics
Zosia Kmietowicz
No abstract text is available yet for this article.
August 10, 2018: BMJ: British Medical Journal
Nils Jan Bleeker, Megan Cain, Mariana Rego, Aimane Saarig, Andrew Chan, Inger Sierevelt, Job N Doornberg, Ruurd L Jaarsma
INTRODUCTION: The purpose of this study is to evaluate the intra- and inter-observer reliability of low-dose protocolled bilateral postoperative Computed Tomography (CT)-assessment of rotational malalignment after intramedullary nailing (IMN) of tibial shaft fractures. MATERIALS AND METHODS: 156 patients were prospectively included with tibial shaft fractures that were treated with IMN in a Level-I Trauma Centre. All patients underwent post-operative bilateral low-dose CT-assessment (effective dose of 0...
July 29, 2018: Injury
Xiao Chen, Hai-Tao Xu, Hong-Jun Zhang, Jing Chen
BACKGROUND: Numerous studies have compared suprapatellar (SP) nailing to infrapatellar (IP) nailing for treatment of tibial shaft fractures; however, the best strategy remains controversial. The aim of this meta-analysis is to assess whether SP or IP nailing is more effective for tibial shaft fractures in adults. METHODS: Literature searches of PubMed, Embase, OVID, Cochrane Library, Web of Science, Chinese Biomedical Literature, Wanfang, Weipu Journal, and CNKI databases were performed up to July 2017...
August 2018: Medicine (Baltimore)
Julius A Bishop, Sean T Campbell, Jonathan-James T Eno, Michael J Gardner
Intramedullary nailing is often the treatment of choice for fractures of the tibia, but postoperative knee pain is common after this procedure. Potential etiologies include implant prominence, injury to intra-articular structures, patellar tendon or fat pad injury, damage to the infrapatellar branch of the saphenous nerve, and altered biomechanics. Depending on the etiology, described treatment options include observation, implant removal, assessment and treatment of injured intra-articular structures, and selective denervation...
August 8, 2018: Journal of the American Academy of Orthopaedic Surgeons
L L E Whitehouse, C E L Smith, J A Poulter, C J Brown, A Patel, T Lamb, L R Brown, E A O'Sullivan, R E Mitchell, I R Berry, R Charlton, C F Inglehearn, A J Mighell
OBJECTIVES: Variants in DLX3 cause Tricho-dento-osseous syndrome (TDO, MIM #190320); a, systemic condition with hair, nail and bony changes, taurodontism and amelogenesis imperfecta (AI), inherited in an autosomal-dominant fashion. Different variants found within this gene are associated with different phenotypic presentations. To date, 6 different DLX3 variants have been reported in TDO. The aim of this paper is to explore and discuss three recently uncovered new variants in DLX3. SUBJECTS AND METHODS: Whole exome sequencing identified a new DLX3 variant in one family, recruited as part of an on-going study of genetic variants associated with AI...
August 10, 2018: Oral Diseases
Irene Álvarez-Mosquera, Silvia Hernáez, Juan Sánchez, Maria Dolores Suárez, Ramón Cisterna
Superficial mycoses are the most frequently diagnosed affections of the stratum corneum of the skin, nails and hair. It is generally caused by the presence of yeasts and dermatophytes. Onychomycosis is the most common infection with an incidence of 80-90% in Europe generally produced by Trichophyton rubrum. The aim of this study is to compare the traditional diagnostic techniques of superficial mycoses with a homemade and wide-spectrum fungal polymerase chain reaction (PCR) technique that amplifies a specific region of the 18S ribosomal RNA (rRNA) directly from samples of scales, nails and hair...
August 9, 2018: Mycopathologia
Mohamed Mustafa Diab, David W Shearer, James G Kahn, Hao-Hua Wu, Brian Lau, Saam Morshed, Linda Chokotho
BACKGROUND: In many low- and middle-income countries, non-surgical management of femoral shaft fractures using skeletal traction is common because intramedullary (IM) nailing is perceived to be expensive. This study assessed the cost of IM nailing and skeletal traction for treatment of femoral shaft fractures in Malawi. METHODS: We used micro-costing methods to quantify the costs associated with IM nailing and skeletal traction. Adult patients who sustained an isolated closed femur shaft fracture and managed at Queen Elizabeth Central Hospital in Malawi were followed from admission to discharge...
August 9, 2018: World Journal of Surgery
Sarah Stewart, Angela Brenton-Rule, Nicola Dalbeth, Ashok Aiyer, Christopher Frampton, Keith Rome
OBJECTIVE: To determine characteristics of the foot and ankle in people with systemic lupus erythematosus (SLE). METHODS: Medline, CINAHL, Sports-Discus, Scopus and Cochrane Library databases were searched up to January 2018. Studies reporting foot- and ankle-related outcomes in the following domains were included: vascular, neurological, musculoskeletal, cutaneous (skin and nail) or pain/function. The Quality Index tool was used to assess methodological quality...
August 6, 2018: Seminars in Arthritis and Rheumatism
David C Shih, P Maureen Cassidy, Kiran M Perkins, Matthew B Crist, Paul R Cieslak, Richard L Leman
Nontuberculous mycobacteria (NTM), ubiquitous in soil and water, usually infect immunocompromised persons. However, even healthy persons are susceptible to infection through percutaneous inoculation. Although 77% of NTM diseases manifest as primarily pulmonary illnesses (1), NTM also infect skin, bones, joints, the lymphatic system, and soft tissue. NTM infections can have incubation periods that exceed 5 years (2), often require prolonged treatment, and can lead to sepsis and death. Extrapulmonary NTM outbreaks have been reported in association with contaminated surgical gentian violet (3), nail salon pedicures (4), and tattoos received at tattoo parlors (5), although few surveillance data have been available for estimating the public health burden of NTM...
August 10, 2018: MMWR. Morbidity and Mortality Weekly Report
Daniel Burchette, Shreya Badhrinarayanan, Tim Hardwick, Rebecca Kampa
Bungee jumping is a recreational sport that is accepted to carry a level of risk. We present the case of a femoral fracture sustained during bungee jumping and examine the published literature on bungee jumping-related injuries. A previously well 31-year old female performed a 200ft bungee jump from a crane. The apparatus was performed as expected and documented on the bystander video footage. As the bungee-cord became taut for the second time, there was an audible crack with accompanying scream. A closed, neurovascularly-intact injury was sustained to her right thigh...
July 2018: Bulletin of Emergency and Trauma
Rehab Ali Ibrahim, Nour El-Hoda Hussien Abdalla, Engy Amr Husssein Shabaan, Noha Bassiouny Hassan Mostafa
BACKGROUND: Scleroderma or systemic sclerosis (SSc) is a rare systemic autoimmune disease. Many conditions mimic the presentation of SSc, especially skin thickening and fibrosis. One of these conditions is scleredema, a rare collagen and mucin deposition disorder which was found to be associated with diabetes mellitus, streptococcal infection or monoclonal gammopathy. CASE PRESENTATION: A 55 years old female presented with insidious onset and progressive course of diffuse skin thickening of face, neck, arms, forearms, thighs, chest, back, and sparing both hands and feet of 6 years duration associated with arthralgia, dysphagia and dyspnea on exertion of 1-year duration...
August 7, 2018: Current Rheumatology Reviews
Tanja Miličević, Ivan Žaja, Deša Tešanović, Maja Radman
Laugier-Hunziker syndrome (LHS) is a rare, benign and acquired disorder characterized by hyperpigmentation of the oral cavity and lips along with longitudinal melanonychia. No underlying systemic abnormalities or malignant predisposition is associated with it. In everyday clinical practice, an endocrinologist encounters certain endocrine conditions (e.g. Addison's disease, McCune-Albright syndrome) that present with, inter alia, mucocutaneous hyperpigmentation. Even though LHS is easily distinguished from endocrine entities mentioned earlier, diagnostic evaluation usually requires skilled and thorough practitioner...
2018: Endocrinology, Diabetes & Metabolism Case Reports
Darryl Auston, David Donohue, Kyle Stoops, Jacob Cox, Miguel Diaz, Brandon Santoni, Hassan Mir
OBJECTIVES: To determine the change in stiffness and horizontal translations of a geriatric supracondylar femur fracture model with the addition of distal segment blocking screws versus proximal (long) segment blocking screws to the standard retrograde intramedullary nail construct. METHODS: Unstable supracondylar femur fractures (OTA/AO 33-A3) were created; all specimens were instrumented with a retrograde intramedullary nail. Specimens were divided into two groups (6 matched pairs per group)...
July 30, 2018: Journal of Orthopaedic Trauma
Limor Nashelsky Zolotov, Eyal Reinstein
BACKGROUND: Nail-patella syndrome (NPS) is characterized by changes in the nails, knees, and elbows, as well as the presence of iliac horns detected by X-ray of the pelvis. A higher occurrence of psychiatric disorders has also been suggested in NPS. Heterozygous mutations in the gene encoding the LIM-homeodomain transcription factor (LMX1B) are identified in most patients with typical clinical findings of NPS. OBJECTIVES: To report on the association between NPS and schizophrenia...
August 2018: Israel Medical Association Journal: IMAJ
Jun Wan, Can Zhang, Yu-Peng Liu, Hong-Bo He
BACKGROUND: The optimal strategy for shepherd's crook deformity correction remains technically challenging. In particular, it is difficult to perform an accurate osteotomy based on the pre-operative correction plan. Moreover, the choice of ideal hardware remains unclear. In addition, when combined with the deformity of knee joint, the sequence of deformity correction is another overlooked factor when making a correction strategy. METHODS: From February 2012 to March 2014, we retrospectively examined a cases series in our department involving the creation of three-dimensional (3D) printing osteotomy templates and inner fixation for shepherd's crook deformity in fibrous dysplasia...
August 6, 2018: International Orthopaedics
Priscila R Oliveira, Marcos C Leonhardt, Vladimir C Carvalho, Kodi E Kojima, Jorge S Silva, Flavia Rossi, Ana Lucia L Lima
BACKGROUND: Diaphyseal fractures of femur and tibia are prominent due to its high incidence and high economic and social impact. Intramedullary nailing (IN) is the surgical procedure of choice. Surgical site infection (SSI) related to this procedure is considered a difficult to treat complication. AIMS: Determine the incidence of SSI after IN of femoral and tibial diaphyseal fractures and evaluate possible risk factors. METHODS: Prospective observational cohort study...
July 27, 2018: Injury
Essam Bakr Abd El-Aal, Hamed Abdou, Shady Mahmoud Ibrahim, Mostafa Taha Eldestawy
BACKGROUND: Onychomycosis is a chronic fungal infection of the nails and the treatment has been proven to be a challenge to healthcare professionals. OBJECTIVE: To evaluate the efficacy of fractional carbon dioxide laser assisted delivery of topical tazarotene versus topical tioconazole in the treatment of onychomycosis. METHODS & MATERIALS: A total of 102 patients with onychomycosis were randomly assigned to groups A and B, both groups were treated with 4 sessions of fractional CO2 laser and followed by topical tazarotene 0...
August 6, 2018: Journal of Dermatological Treatment
Martin N Zaiac, Jorge Ocampo-Garza
No abstract text is available yet for this article.
August 3, 2018: Journal of the American Academy of Dermatology
Jacob E Vaughn, Ronit V Shah, Tarek Samman, Jacob Stirton, Jiayong Liu, Nabil A Ebraheim
AIM: To analyze the literature on efficacy of dynamamization vs exchange nailing in treatment of delayed and non-union femur fractures. METHODS: Ultimately, 31 peer-reviewed articles with 644 exchanged nailing patients and 131 dynamization patients were identified and analyzed. The following key words were inputted in different combinations in order to search the field of publications in its entirety: "non-union", "delayed union", "ununited", "femur fracture", "femoral fracture", "exchange nailing", "dynaiz(s)ation", "secondary nailing", "dynamic", "static", and "nail revision"...
July 18, 2018: World Journal of Orthopedics
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