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Antimicrobials in dentistry

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https://www.readbyqxmd.com/read/30087739/assessment-of-photodynamic-therapy-and-nanoparticles-effects-on-caries-models
#1
Ali Saafan, Mohamed H Zaazou, Marwa K Sallam, Osama Mosallam, Heba A El Danaf
AIM: To assess the antibacterial competence of 650 nm diode laser, Methylene Blue (MB) and Silver Nano-Particles (Ag NPs) on Streptococcus mutans in biofilm-induced caries models. MATERIAL AND METHODS: One hundred eighty specimens were prepared and equally divided into 6 groups. One group was untreated (control), and the others were subjected to either MB, laser, Ag NPs, the combination of MB and Laser or MB, laser and Ag NPs. RESULTS: Comparison of the log10 mean Colony Forming Units per millilitre (CFU/ml) values of each of the treated 5 groups and the control group was found statistically significant (P-value < 0...
July 20, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/30033323/an-overview-of-application-of-silver-nanoparticles-for-biomaterials-in-dentistry
#2
REVIEW
Ranjeet A Bapat, Tanay V Chaubal, Chaitanya P Joshi, Prachi R Bapat, Hira Choudhury, Manisha Pandey, Bapi Gorain, Prashant Kesharwani
Oral cavity is a gateway to the entire body and protection of this gateway is a major goal in dentistry. Plaque biofilm is a major cause of majority of dental diseases and although various biomaterials have been applied for their cure, limitations pertaining to the material properties prevent achievement of desired outcomes. Nanoparticle applications have become useful tools for various dental applications in endodontics, periodontics, restorative dentistry, orthodontics and oral cancers. Off these, silver nanoparticles (AgNPs) have been used in medicine and dentistry due to its antimicrobial properties...
October 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29925870/effects-of-water-aging-for-6-months-on-the-durability-of-a-novel-antimicrobial-and-protein-repellent-dental-bonding-agent
#3
Ning Zhang, Ke Zhang, Michael D Weir, David J Xu, Mark A Reynolds, Yuxing Bai, Hockin H K Xu
Biofilms at the tooth-restoration bonded interface can produce acids and cause recurrent caries. Recurrent caries is a primary reason for restoration failures. The objectives of this study were to synthesize a novel bioactive dental bonding agent containing dimethylaminohexadecyl methacrylate (DMAHDM) and 2-methacryloyloxyethyl phosphorylcholine (MPC) to inhibit biofilm formation at the tooth-restoration margin and to investigate the effects of water-aging for 6 months on the dentin bond strength and protein-repellent and antibacterial durability...
June 21, 2018: International Journal of Oral Science
https://www.readbyqxmd.com/read/29888127/cytotoxicity-and-antimicrobial-action-of-selected-phytochemicals-against-planktonic-and-sessile-streptococcus-mutans
#4
Marta Ribeiro, Joana Malheiro, Liliana Grenho, Maria Helena Fernandes, Manuel Simões
Background: Dental caries remains the most prevalent and costly oral infectious disease worldwide, encouraging the search for new and more effective antimicrobials. Therefore, the aim of this work was to study the antimicrobial action of selected phytochemicals (eugenol, citronellol, sabinene hydrate, trans-cinnamaldehyde, terpineol and cinnamic acid) against Streptococcus mutans in planktonic and biofilm states as well as the cytotoxicity of these compounds. Methods: The antibacterial activity of the selected compounds was evaluated by the determination of the minimal bactericidal concentration...
2018: PeerJ
https://www.readbyqxmd.com/read/29886841/phyto-fabrication-of-zno-nanoparticles-using-piper-betel-aqueous-extract-and-evaluation-of-its-applicability-in-dentistry
#5
P Shubha, K Byrappa, K Namratha, Jit Chaterjee, M S Mustak
BACKGROUND: Facile, environmental friendly synthesis of metal oxide nanoparticles is of paramount importance when its biological applications are considered. OBJECTIVE: Current study reports phyto-fabrication of Zinc oxide nanoparticles using aqueous extract of Piper betel leaves as stabilizing and capping agent using co-precipitation method. RESULTS: P betel synthesized ZnO nanoparticles (PZnO) was characterized using Powder X-ray diffraction, UV-Visible spectroscopy, scanning electron microscopy and dynamic light scattering...
June 10, 2018: Pharmaceutical Nanotechnology
https://www.readbyqxmd.com/read/29745321/selected-applications-for-current-polymers-in-prosthetic-dentistry-state-of-the-art
#6
Maciej Kawala, Joanna Smardz, Lukasz Adamczyk, Natalia Grychowska, Mieszko Wieckiewicz
BACKGROUND: Polymers are widely applied in medicine, including dentistry, i.e. in prosthodontics. AIM: The following paper is aimed at demonstrating the applications of selected modern polymers in prosthetic dentistry based on the reported literature. MATERIAL AND METHODS: The study was conducted using the PubMed, SCOPUS and CINAHL databases in relation to documents published during 1999-2017. The following keywords were used: polymers with: prosthetic dentistry, impression materials, denture base materials, bite registration materials, denture soft liners, occlusal splint materials and 3D printing...
May 10, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29681899/phenalen-1-one-mediated-antimicrobial-photodynamic-therapy-antimicrobial-efficacy-in-a-periodontal-biofilm-model-and-flow-cytometric-evaluation-of-cytoplasmic-membrane-damage
#7
Fabian Cieplik, Viktoria-Sophia Steinwachs, Denise Muehler, Karl-Anton Hiller, Thomas Thurnheer, Georgios N Belibasakis, Wolfgang Buchalla, Tim Maisch
In light of increasing resistance toward conventional antibiotics and antiseptics, antimicrobial photodynamic therapy (aPDT) may be a valuable alternative, especially for use in dentistry. In this regard, photosensitizers (PS) based on a phenalen-1-one structure seem to be especially favorable due to their high singlet oxygen quantum yield. However, the actual target structures of phenalen-1-one-mediated aPDT are still unclear. The aim of the present study was to investigate the antimicrobial efficacy of aPDT mediated by phenalen-1-one derivatives SAPYR and SAGUA for inactivation of a polymicrobial biofilm consisting of three putative periodontal pathogens in vitro and to get first insights in the mechanism of action of phenalen-1-one-mediated aPDT by assessing damage of cytoplasmic membranes...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29678327/antibacterial-quaternary-ammonium-compounds-in-dental-materials-a-systematic-review
#8
REVIEW
Pooyan Makvandi, Rezvan Jamaledin, Mostafa Jabbari, Nasser Nikfarjam, Assunta Borzacchiello
OBJECTIVE: Quaternary ammonium compounds (QACs) represent one of the most effective classes of disinfectant agents in dental materials and resin nanocomposites. This reviews aims to give a wide overview on the research in the field of antibacterial QACs in dental materials and nanocomposites. METHOD: An introduction to dental materials components as well as the microorganisms and methods of evaluation for the antimicrobial assays are presented. Then, the properties and synthesis route of QACs, as monomer and filler, are shown...
June 2018: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29385687/assessing-the-knowledge-attitudes-and-behaviors-of-human-and-animal-health-students-towards-antibiotic-use-and-resistance-a-pilot-cross-sectional-study-in-the-uk
#9
Oliver James Dyar, Holly Hills, Lara-Turiya Seitz, Alex Perry, Diane Ashiru-Oredope
The Global Action Plan on Antimicrobial Resistance highlights the importance of training all healthcare professionals. No study has assessed patterns of students' knowledge, attitudes and practices concerning antibiotic use simultaneously across different healthcare course types. We conducted a cross-sectional multi-center survey among UK students. The survey was advertised through local survey coordinators at 25 universities. The online survey was accessible from 10th October to 17th November 2016 (before European Antibiotic Awareness Day)...
January 30, 2018: Antibiotics
https://www.readbyqxmd.com/read/29378256/curcumin-mediated-photodynamic-therapy-for-the-treatment-of-oral-infections-a-review
#10
REVIEW
Carolina Santezi, Bárbara Donadon Reina, Lívia Nordi Dovigo
BACKGROUND: Recent evidences show the promising applications of Curcumin (CUR) against different diseases, including some of the main oral pathologies. The objective of this review paper was to catalog articles that investigated the photodynamic effect of CUR for oral diseases in the last 15 years. METHODS: The establishment of defined criteria for data collection was proposed and a total of 173 articles were identified, but only 26 were eligible for full text reading...
March 2018: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29354775/-in-vitro-antimicrobial-effect-of-different-root-canal-sealers-against-oral-pathogens
#11
A Monajemzadeh, S Ahmadi Asoor, S Aslani, B Sadeghi-Nejad
Background and Purpose: Root canal therapy is the primary method for the treatment of an infected pulp in modern dentistry. The main aim of endodontic treatment is the elimination of bacteria and their products from infected root canals. In this study, we attempted to investigate the antimicrobial activity of three root canal sealers against oral pathogens. Materials and Methods: The antimicrobial effectiveness of three endodontic sealers with different chemical compositions, namely resin (AH 26), zinc oxide eugenol (ZOE), and mineral trioxide aggregate (MTA), against Candida albican s, Streptococcus sanguis, Streptococcus salivarius, Streptococcus mutans , and Lactobacillus casei was assayed by agar well diffusion method (AWDM)...
June 2017: Advances in Medical Mycology (Iran)
https://www.readbyqxmd.com/read/29318387/antimicrobial-activity-of-psidium-cattleianum-associated-with-calcium-hydroxide-against-enterococcus-faecalis-and-candida-albicans-an-in-vitro-study
#12
Jorgiana Sangalli, Elerson Gaetti Jardim Júnior, Carlos Roberto Emerenciano Bueno, Rogério Castilho Jacinto, Gustavo Sivieri-Araújo, João Eduardo Gomes Filho, Luciano Tavares Ângelo Cintra, Eloi Dezan Junior
OBJECTIVE: Evaluate, in vitro, the antimicrobial activity of Psidium cattleianum leaf extracts combined with calcium hydroxide against Enterococcus faecalis and Candida albicans biofilm. MATERIALS AND METHODS: Dentin specimens obtained from extracted bovine incisors were infected during 14 days with E. faecalis ATCC 29212 and C. albicans ATCC 10231. The specimens were filled with calcium hydroxide pastes prepared with the following vehicles: Psidium cattleianum ethanolic, Psidium cattleianum propylene glycolic, distilled water, and saline as control...
July 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29316616/revitalising-silver-nitrate-for-caries-management
#13
REVIEW
Sherry Shiqian Gao, Irene Shuping Zhao, Steve Duffin, Duangporn Duangthip, Edward Chin Man Lo, Chun Hung Chu
Silver nitrate has been adopted for medical use as a disinfectant for eye disease and burned wounds. In dentistry, it is an active ingredient of Howe's solution used to prevent and arrest dental caries. While medical use of silver nitrate as a disinfectant became subsidiary with the discovery of antibiotics, its use in caries treatment also diminished with the use of fluoride in caries prevention. Since then, fluoride agents, particularly sodium fluoride, have gained popularity in caries prevention. However, caries is an infection caused by cariogenic bacteria, which demineralise enamel and dentine...
January 6, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29243020/effect-of-1064-nm-q-switched-nd-yag-laser-on-invasiveness-and-innate-immune-response-in-keratinocytes-infected-with-candida-albicans
#14
Adone Baroni, Anna De Filippis, Giovanni Oliviero, Alessandra Fusco, Brunella Perfetto, Elisabetta Buommino, Giovanna Donnarumma
Candida albicans is an opportunistic pathogen commensal in the oral cavity, vagina, and healthy skin. Common therapeutic options for fungal infections are topical or systemic antifungal drugs. Recently, in cutaneous pathologies, lasers and light-based treatments have emerged showing few contraindications and minimal side effects. The Q-switched (Nd-YAG) laser at a wavelength of 1064 nm has been shown to be useful in dermatology, dentistry, and some other medical specialties. It is used to treat onychomycoses, warts, and wounds and in some other treatments...
July 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29236898/in-vitro-analysis-of-a-local-polymeric-device-as-an-alternative-for-systemic-antibiotics-in-dentistry
#15
Talita Girio Carnaval, Flávia Gonçalves, Marcelo Munhóes Romano, Luiz Henrique Catalani, Marcia Alves Pinto Mayer, Victor Elias Arana-Chávez, Alexander Cassandri Nishida, Thais Claudino Lage, Carlos Eduardo Francci, Carlos Alberto Adde
The development of a biodegradable material with antimicrobial properties for local applications is required in the prevention and treatment of infectious diseases. The objective of this study was to produce blends of poly-L-lactide acid (PLLA) synthetic polymer associated with several antimicrobials, as an alternative in the prevention and treatment of infections, as well as to evaluate its cytotoxicity, release of antimicrobials and inhibit bacteria growth. Blends of PLLA added with 20% Amoxicillin, Metronidazole, Clindamycin or Azithromicyn were used to produce Films (F) or Meshs (M) by casting and electrospinning methods, respectively...
December 7, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/29225280/quaternary-ammonium-compounds-in-dental-restorative-materials
#16
Yu Zhang, Yinyan Chen, Yuntong Hu, Fang Huang, Yuhong Xiao
Quaternary ammonium compounds (QACs) have been used widely in medicine, owing to their antimicrobial properties. They also have strong permeability, stable performance, low skin irritation, low toxicity, low corrosion, lasting biological effects and so on, comparing with other antimicrobial agents. At the end of last century, polymerizable quaternary ammonium antimicrobial monomers had been synthesized and applied in dentistry, in order to reduce or prevent microbial biofilm formation on dental materials surfaces...
March 30, 2018: Dental Materials Journal
https://www.readbyqxmd.com/read/29207708/in-vitro-anti-cariogenic-plaque-effects-of-essential-oils-extracted-from-culinary-herbs
#17
Kornsit Wiwattanarattanabut, Suwan Choonharuangdej, Theerathavaj Srithavaj
Introduction: Cariogenic bacteria including mutans streptococci and lactobacilli are partly but significantly involved in dental caries development. An effective prevention strategy against dental caries is to decrease the accumulation of this microbiota either in planktonic or in biofilm form. Aim: To examine the antimicrobial and anti-plaque effects of some culinary herbs (spices), so the herbs are plausibly used as alternative and effective herbal plaque control supplements to promote good oral health...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29172346/antibiotic-guardians-the-role-of-the-dental-profession
#18
Anwen L Cope, Michael A O Lewis
The increasing emergence of antibiotic resistance is a major international public health problem. As a consequence, it is essential that steps are taken to conserve the effectiveness of existing antimicrobial agents. Consumption of antibiotics is the prime contributor to the development of resistance. General dental practitioners write almost 1 out of 10 prescriptions for antibiotics in primary care within the UK and therefore the prudent prescribing of antibiotics in dentistry has never been more vital. This paper outlines the impact of antimicrobial resistance on modern healthcare, describes the current use of antibiotics in general dental practice, and recommends pragmatic ways in which dental practitioners can evaluate and optimize their prescribing...
April 2017: Dental Update
https://www.readbyqxmd.com/read/29168274/antimicrobial-properties-of-calcium-hydroxide-dressing-when-used-for-long-term-application-a-systematic-review
#19
REVIEW
Garima Sharma, Hany Mohamed Aly Ahmed, Peter S Zilm, Giampiero Rossi-Fedele
This review aims to evaluate the antimicrobial efficacy of calcium hydroxide against endodontic pathogens when used for 7 days or longer. A systematic electronic literature search was performed in the PubMed, Embase and EBSCO Dentistry & Oral Sciences Source databases using appropriate key words to identify investigations written in the English language that examined the association between the contact time of intracanal calcium hydroxide dressing and its antimicrobial properties. There were no exclusions based on study design...
April 2018: Australian Endodontic Journal: the Journal of the Australian Society of Endodontology Inc
https://www.readbyqxmd.com/read/29155536/antimicrobial-resistance-and-antibiotic-prescribing-in-dental-practice
#20
REVIEW
Nikolaus O A Palmer
The purpose of this paper is to review the principles of antibiotic prescribing in light of the increasing worldwide problem of antimicrobial resistance and the evidence of inappropriate use of antibiotics in dentistry. Guidance on the management of dental infections and antibiotic prophylaxis based on a review of the scientific evidence will be given to ensure good patient care. Clinical relevance: To discuss the relevance of legislation around antimicrobial prescribing and antimicrobial stewardship for dentists...
December 2016: Dental Update
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