keyword
https://read.qxmd.com/read/38584897/bladder-perforation-and-vesico-haematoma-fistula-an-uncommon-complication-of-rectus-sheath-haematoma
#21
JOURNAL ARTICLE
Novena Lin Sing Cheng, Chung Wai Wong, Wen Ming Yu, Kim Hung Tsang
INTRODUCTION: Rectus sheath haematoma (RSH) has become increasingly common but is often underdiagnosed. Prompt diagnosis will avoid unnecessary investigations and procedures, resulting in early treatment and a better outcome. CASE DESCRIPTION: We described a case of a spontaneous RSH with intraperitoneal extension and formation of a vesico-haematoma fistula, which was initially misdiagnosed as a urinary tract infection. The diagnosis was made ten days after admission, when a CT scan showed an over-16 cm RSH with intraperitoneal extension, bladder perforation and a vesico-haematoma fistula...
2024: European Journal of Case Reports in Internal Medicine
https://read.qxmd.com/read/38583833/review-n1-methyl-pseudouridine-m1%C3%AE-friend-or-foe-of-cancer
#22
REVIEW
Alberto Rubio-Casillas, David Cowley, Mikolaj Raszek, Vladimir N Uversky, Elrashdy M Redwan
Due to the health emergency created by SARS-CoV-2, the virus that causes the COVID-19 disease, the rapid implementation of a new vaccine technology was necessary. mRNA vaccines, being one of the cutting-edge new technologies, attracted significant interest and offered a lot of hope. The potential of these vaccines in preventing admission to hospitals and serious illness in people with comorbidities has recently been called into question due to the vaccines' rapidly waning immunity. Mounting evidence indicates that these vaccines, like many others, do not generate sterilizing immunity, leaving people vulnerable to recurrent infections...
April 5, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38581075/lung-ultrasound-and-procalcitonin-improving-antibiotic-management-and-avoiding-radiation-exposure-in-pediatric-critical-patients-with-bacterial-pneumonia-a-randomized-clinical-trial
#23
RANDOMIZED CONTROLLED TRIAL
Carmina Guitart, Sara Bobillo-Perez, Javier Rodríguez-Fanjul, José Luis Carrasco, Pedro Brotons, Maria Goretti López-Ramos, Francisco José Cambra, Mònica Balaguer, Iolanda Jordan
BACKGROUND: Pneumonia is a major public health problem with an impact on morbidity and mortality. Its management still represents a challenge. The aim was to determine whether a new diagnostic algorithm combining lung ultrasound (LUS) and procalcitonin (PCT) improved pneumonia management regarding antibiotic use, radiation exposure, and associated costs, in critically ill pediatric patients with suspected bacterial pneumonia (BP). METHODS: Randomized, blinded, comparative effectiveness clinical trial...
April 6, 2024: European Journal of Medical Research
https://read.qxmd.com/read/38576141/a-rare-case-of-small-bowel-obstruction-in-a-15-year-old-girl-internal-hernia-associated-with-meckel-s-diverticulum
#24
JOURNAL ARTICLE
David Daoyong Lai, Xi Zhen Low, Yang Yang Lee, Weizhong Jonathan Sng
BACKGROUND Meckel's diverticulum is a congenital remnant of the omphalomesenteric duct and is the most common congenital gastrointestinal malformation. Most patients are asymptomatic, but a rare presentation is with subacute small bowel obstruction (SBO) due to herniation of bowel loops through an internal hernia formed by the Meckel's diverticulum and adjacent mesentery that forms an internal hernia. This report is of a 15-year-old girl presenting as an emergency with vomiting and small bowel obstruction due to an internal hernia associated with Meckel's diverticulum...
April 5, 2024: American Journal of Case Reports
https://read.qxmd.com/read/38571849/medical-management-of-cesarean-scar-ectopic-pregnancy-a-unique-approach
#25
Pankaj Salvi, Vidya Gaikwad, Ayushi Bhadoriya, Sanjay Ponde
One of the rarest types of ectopic pregnancy, with an incidence of 1:1,800, is cesarean scar ectopic pregnancy. Here, we report the case of a 28-year-old woman who had undergone two previous cesarean sections. She arrived at our labor room with per vaginal spotting and abdominal pain with an ultrasound that revealed a cesarean scar ectopic pregnancy. The initial beta-human chorionic gonadotropin (β-hCG) value upon admission was 27,133 mIU/mL. Her ultrasound findings were confirmed with magnetic resonance imaging...
March 2024: Curēus
https://read.qxmd.com/read/38571647/evidence-based-intrapartum-care-during-vaginal-births-direct-observations-in-a-tertiary-care-hospital-in-central-sri-lanka
#26
JOURNAL ARTICLE
Thilini Kumari Weerasingha, Chathura Ratnayake, R M Abeyrathne, Sampath U B Tennakoon
BACKGROUND: Evidence-based practice (EBP) is an effective approach to improve maternal and newborn outcomes at birth. OBJECTIVE: This study aimed to assess the current intrapartum practices of a tertiary care hospital in Central Province, Sri Lanka, during vaginal births. The benchmark for this assessment was the World Health Organisation's (WHO) recommendations on intrapartum care for a positive childbirth experience. METHODS: An observational study was conducted at the delivery room of Teaching Hospital, Peradeniya with the participation of 196 labouring women who were selected using systematic random sampling...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38562231/pulmonary-embolism-in-hospitalized-covid-19-patients-short-and-long-term-clinical-outcomes
#27
JOURNAL ARTICLE
Inge H Y Luu, Jacqueline Buijs, Jasenko Krdzalic, Martijn D de Kruif, Guy J M Mostard, Hugo Ten Cate, Tom P J Dormans, Remy L M Mostard, Math P G Leers, Daan J L van Twist
INTRODUCTION: Pulmonary embolism (PE) is a frequent complication in COVID-19. However, the influence of PE on the prognosis of COVID-19 remains unclear as previous studies were affected by misclassification bias. Therefore, we evaluated a cohort of COVID-19 patients whom all underwent systematic screening for PE (thereby avoiding misclassification) and compared clinical outcomes between patients with and without PE. MATERIALS AND METHODS: We included all COVID-19 patients who were admitted through the ED between April 2020 and February 2021...
August 2023: Thromb Update
https://read.qxmd.com/read/38558747/delayed-postoperative-intracerebral-hemorrhage-associated-with-oral-multikinase-inhibitor-therapy-for-cancer-a-case-report
#28
Vishal C Patel, Asha Krishnakumar, Edward H Yang, Andrew S Poklepovic, William C Broaddus
Regorafenib is a multikinase inhibitor with anti-vascular endothelial growth factor receptor (VEGF) activity used as an antiangiogenic agent for metastatic colorectal cancer treatment and has been studied as a potential therapeutic agent for several other cancer treatments. Adverse reactions commonly reported with the use of regorafenib and similar oral multikinase inhibitors include hemorrhage, gastrointestinal fistulas, hypertension, and incomplete wound healing. We report a case of a 59-year-old man with metastatic colorectal adenocarcinoma post-colostomy on regorafenib treatment presenting to the emergency department with altered mental status...
February 2024: Curēus
https://read.qxmd.com/read/38558439/home-based-management-on-hospital-re-admission-rates-in-copd-patients-a-systematic-review
#29
REVIEW
Rita Corcoran, Zena Moore, Pinar Avsar, Bridget Murray
AIM: To determine the impact of home-based management on hospital re-admission rates in patients with chronic obstructive pulmonary disease (COPD). DESIGN: Systematic review methodology was utilized, combining meta-analysis, where appropriate, or a narrative analysis of the data from included studies. DATA SOURCES: Electronic databases CINAHL, MEDLINE, PubMed, Embase and SAGE journals for primary papers, 2015 to 2021, were searched between December 2020 and March 2021, followed by hand-searching key journals, and reference lists of retrieved papers...
April 1, 2024: Journal of Advanced Nursing
https://read.qxmd.com/read/38553157/predicting-time-to-intubation-after-critical-care-admission-using-machine-learning-and-cured-fraction-information
#30
JOURNAL ARTICLE
Michela Venturini, Ingrid Van Keilegom, Wouter De Corte, Celine Vens
Intubation for mechanical ventilation (MV) is one of the most common high-risk procedures performed in Intensive Care Units (ICUs). Early prediction of intubation may have a positive impact by providing timely alerts to clinicians and consequently avoiding high-risk late intubations. In this work, we propose a new machine learning method to predict the time to intubation during the first five days of ICU admission, based on the concept of cure survival models. Our approach combines classification and survival analysis, to effectively accommodate the fraction of patients not at risk of intubation, and provide a better estimate of time to intubation, for patients at risk...
April 2024: Artificial Intelligence in Medicine
https://read.qxmd.com/read/38552588/readmissions-after-traumatic-brain-injury-in-the-nationwide-readmissions-database
#31
JOURNAL ARTICLE
Collin Pilkington, Tarendeep Thind, Stephen M Bowman, Kevin Sexton, Mary Katherine Kimbrough, Austin Porter, Ben Davis, Judy Bennett, Avi Bhavaraju, Hanna K Jensen
INTRODUCTION: Readmissions after a traumatic brain injury (TBI) can have severe impacts on long-term health outcomes as well as rehabilitation. The aim of this descriptive study was to analyze the Nationwide Readmissions Database to determine possible risk factors associated with readmission for patients who previously sustained a TBI. METHODS: This retrospective study used data from the Nationwide Readmissions Database to explore gender, age, injury severity score, comorbidities, index admission hospital size, discharge disposition of the patient, and cause for readmission for adults admitted with a TBI...
March 28, 2024: Journal of Surgical Research
https://read.qxmd.com/read/38549645/exploring-effective-coping-strategies-for-wives-living-with-spouses-who-have-alcohol-dependence-insights-from-focus-group-discussions
#32
JOURNAL ARTICLE
Jyothi Quadras, M Anitharani, R Johnson Pradeep
BACKGROUND: Alcohol dependence is a prevalent issue worldwide. The wives of persons with alcohol dependence (WPAD) often experience several psychological, physical, and social problems, and it is essential to identify their coping strategies. This study aims to explore the coping strategies employed by WPAD by conducting a focus group discussion (FGD). MATERIALS AND METHODS: This study was conducted among wives of persons with alcohol dependence during their husband's admission in the departments of Psychiatry and gastroenterology of St...
2024: Journal of Education and Health Promotion
https://read.qxmd.com/read/38549472/relationship-between-concentration-of-air-pollutants-and-frequency-of-hospitalisations-due-to-respiratory-diseases
#33
JOURNAL ARTICLE
Anna Grzywa-Celińska, Adam Krusiński, Katarzyna Dos Santos Szewczyk, Ewa Kurys-Denis, Janusz Milanowski
INTRODUCTION AND OBJECTIVE: Smog, which contains fine dusts, non-metal oxides, metals and organic compounds can have irritating, allergenic and immunomodulatory effects leading to the development of respiratory diseases and their exacerbations. The aim of the study was to search for a relationship between concentrations of air pollutants and the frequency of hospitalizations due to exacerbation of asthma, chronic obstructive pulmonary disease, or abnormalitis in breathing. MATERIAL AND METHODS: Hospital admission data was accessed from the hospital digital in-formation system...
March 25, 2024: Annals of Agricultural and Environmental Medicine: AAEM
https://read.qxmd.com/read/38549131/the-association-between-midwifery-staffing-and-reported-harmful-incidents-a-cross-sectional-analysis-of-routinely-collected-data
#34
JOURNAL ARTICLE
Lesley Turner, Jane Ball, Paul Meredith, Ellen Kitson-Reynolds, Peter Griffiths
BACKGROUND: Independent inquiries have identified that appropriate staffing in maternity units is key to enabling quality care and minimising harm, but optimal staffing levels can be difficult to achieve when there is a shortage of midwives. The services provided and how they are staffed (total staffing, skill-mix and deployment) have been changing, and the effects of workforce changes on care quality and outcomes have not been assessed. This study aims to explore the association between daily midwifery staffing levels and the rate of reported harmful incidents affecting mothers and babies...
March 28, 2024: BMC Health Services Research
https://read.qxmd.com/read/38549048/a-case-report-of-an-atypical-severe-case-of-skin-picking-disorder-managed-by-a-multidisciplinary-team
#35
JOURNAL ARTICLE
Marissa A LeBlanc, Mary-Ann Hudec, Lutz Weise
BACKGROUND: While skin picking disorder remains relatively common, it often does not present to psychiatry until significant morbidity or comorbidities are reached. It is described as recurrent picking of skin leading to skin lesions, with repeated attempts to decrease or stop skin picking. It is also often associated with significant distress or functional impairment. There has been limited research in this specific disorder and treatment efficacy has often been poor in severe cases...
March 28, 2024: BMC Psychiatry
https://read.qxmd.com/read/38545251/rate-pressure-product-is-a-novel-predictor-for-short-and-long-term-mortality-in-patients-with-acute-coronary-syndrome-undergoing-primary-pci-immediate-invasive-strategy
#36
JOURNAL ARTICLE
Jian Zhou, Ya-Jie Li, Xiao-Dong Zhou, Li-Juan Wang
BACKGROUND: Rate-pressure product (RPP) calculated by multiplying heart rate by systolic blood pressure, is a convenient indicator closely associated with cardiac work or myocardial oxygen consumption. It has been reported to relate strongly to important indices of cardiovascular risk in patients with myocardial ischemia. However, its relationship with short- and long-term mortality in patients with acute coronary syndrome (ACS) undergoing primary PCI/immediate invasive strategy has not been defined...
2024: Clinical Interventions in Aging
https://read.qxmd.com/read/38545089/the-rise-of-home-death-in-the-covid-19-pandemic-a-population-based-study-of-death-certificate-data-for-adults-from-32-countries-2012-2021
#37
JOURNAL ARTICLE
Sílvia Lopes, Andrea Bruno de Sousa, Mayra Delalibera, Elizabeth Namukwaya, Joachim Cohen, Barbara Gomes
BACKGROUND: During the coronavirus 2019 disease (COVID-19) pandemic, health systems had to respond to the needs of COVID-19 patients, while caring for patients with other life-threatening conditions. Pandemics, such as the COVID-19 pandemic, stir global health and mortality patterns. This is likely to include trends in dying places. In this paper, we examine trends in place of death for adults in 32 countries, comparing the initial COVID-19 pandemic years (2020-2021) with the eight years before the pandemic (2012-2019)...
February 2024: EClinicalMedicine
https://read.qxmd.com/read/38540650/predicting-mortality-for-covid-19-patients-admitted-to-an-emergency-department-using-early-warning-scores-in-poland
#38
JOURNAL ARTICLE
Patryk Rzońca, Sławomir Butkiewicz, Paula Dobosz, Artur Zaczyński, Marcin Podgórski, Robert Gałązkowski, Waldemar Wierzba, Katarzyna Życińska
COVID-19 disease is characterised by a wide range of symptoms that in most cases resemble flu or cold. Early detection of infections, monitoring of patients' conditions, and identification of patients with worsening symptoms became crucial during the peak of pandemic. The aim of this study was to assess and compare the performance of common early warning scores at the time of admission to an emergency department in predicting in-hospital mortality in patients with COVID-19. The study was based on a retrospective analysis of patients with SARS-CoV-2 infection admitted to an emergency department between March 2020 and April 2022...
March 19, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38539299/pre-admission-oral-clonidine-to-reduce-severe-pre-operative-anxiety-in-pediatric-patients-with-behavioral-disorders-a-case-series
#39
Nicole Verdecchia, Ryan Nelson, Shante White, Franklyn Cladis
Controlling preoperative anxiety is necessary in pediatric patients to avoid adverse effects such as emergence delirium, behavioral problems, post-traumatic stress disorder, anxiety prior to future procedures, and increased analgesic doses in the recovery room. Some patients, especially ones with behavioral issues, have a difficult time arriving at the hospital. Medications given at home can be helpful. We describe a case series of six patients who received pre-admission oral clonidine prior to arrival to the hospital...
February 20, 2024: Children
https://read.qxmd.com/read/38533166/diagnostic-and-surgical-implications-of-non-occlusive-mesenteric-ischemic-ileus-associated-with-common-celiacomesenteric-trunk-a-case-report-and-literature-review
#40
Paul Joon Koo Choi, Jigyasha Pradhan, Sania Thite, Reshma Pydi, Gagan Sathya Prakash, Tiffany-Marie Golek, Sarah Moore, Ajay Shah, Hanasoge Girishkumar
The celiacomesenteric trunk (CMT), an exceedingly rare anatomic variant uniting the celiac artery and superior mesenteric artery (SMA), holds significant clinical and surgical implications. Despite its rarity, understanding these implications is crucial for effective management. This report outlines the case of a 99-year-old female presenting with septic shock and abdominal pain, with imaging revealing an incidental CMT. This paper aims to elucidate the surgical implications associated with CMT through a comprehensive case review and literature search...
February 2024: Curēus
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