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Response to ECG

Sachin Nayyar, Pawel Kuklik, George Tomlinson, Adrian Suszko, Vijay S Chauhan
BACKGROUND: QRS abnormalities may not be apparent in sinus rhythm in electrically stable cardiomyopathy patients who can have quiescent but highly arrhythmogenic substrate. Here, we test the hypothesis that differential changes in QRS construction during right-ventricular apex pacing (RVP) as opposed to atrial pacing (AP) will identify latent substrate for ventricular arrhythmias (VA) and death. METHODS: Forty-patients with cardiomyopathy free of VA underwent baseline 114-electrode body-surface ECG during AP (100 bpm) and RVP (100 and 120 bpm)...
December 4, 2018: Pacing and Clinical Electrophysiology: PACE
C Strumann, K Flägel, T Emcke, J Steinhäuser
BACKGROUND: In response to a rising shortage of general practitioners (GPs), physicians in general internal medicine (GIM) have become part of the German primary care physician workforce. Previous studies have shown substantial differences in practice patterns between both specialties. The aim of this study was to analyse and compare the application of procedures by German GPs and GIM physicians based on routine data. METHODS: The Association of Statutory Health Insurance Physicians in the federal state Schleswig-Holstein (Northern Germany) provided invoicing data of the first quarters of 2013 and 2015...
December 3, 2018: BMC Family Practice
Jarren C Kay, Gerald C Claghorn, Zoe Thompson, Thomas G Hampton, Theodore Garland
Changes in cardiac function that occur with exercise training have been studied in detail, but those accompanying evolved increases in the duration or intensity of physical activity are poorly understood. To address this gap, we studied electrocardiograms (ECGs) of mice from an artificial selection experiment in which four replicate lines are bred for high voluntary wheel running (HR) while four non-selected lines are maintained as controls (C). ECGs were recorded using an ECGenie (Mouse Specifics, Inc.) both before and after six days of wheel access (as used in the standard protocol to select breeders)...
November 30, 2018: Physiology & Behavior
Carolina Varon, Jesus Lazaro, Juan Bolea, Alberto Hernando, Jordi Aguilo, Eduardo Gil, Sabine Van Huffel, Raquel Bailon
OBJECTIVE: This paper proposes an approach to better estimate the sympathovagal balance (SB) and the respiratory sinus arrhythmia (RSA) after separating respiratory influences from the heart rate (HR). METHODS: The separation is performed using orthogonal subspace projections and the approach is first tested using simulated HR and respiratory signals with different spectral properties. Then, RSA and SB are estimated during autonomic blockade and stress using the proposed approach and the classical heart rate variability (HRV) analysis...
December 3, 2018: IEEE Journal of Biomedical and Health Informatics
José Luís Martins, Anabela Gonzaga, José Santos
No abstract text is available yet for this article.
December 2018: Revista Española de Cardiología
Rita Brito, Louis-Paulin Mondouagne, Carine Stettler, Christophe Combescure, Haran Burri
BACKGROUND: Handheld ECG recorders may have algorithms which automatically inform the user of presence of arrhythmia. The main objectives of this study were to evaluate the accuracy of the arrhythmia diagnosis algorithm of Beurer ME90 recorder to diagnose atrial fibrillation (AF)/flutter, and to evaluate whether recording technique (finger versus precordial) affects diagnostic performance. METHODS: Consecutive patients admitted at the cardiology ward of a tertiary care hospital were enrolled...
November 2018: Journal of Electrocardiology
Katja E Odening, Ilona Bodi, Gerlind Franke, Raphaela Rieke, Anna Ryan de Medeiros, Stefanie Perez-Feliz, Hannah Fürniss, Lea Mettke, Konstantin Michaelides, Corinna N Lang, Johannes Steinfurt, Naga Deepa Pantulu, David Ziupa, Marius Menza, Manfred Zehender, Heiko Bugger, Remi Peyronnet, Jan C Behrends, Zoltan Doleschall, Axel Zur Hausen, Christoph Bode, Genevieve Jolivet, Michael Brunner
Aims: Short-QT syndrome 1 (SQT1) is an inherited channelopathy with accelerated repolarization due to gain-of-function in HERG/IKr. Patients develop atrial fibrillation, ventricular tachycardia (VT), and sudden cardiac death with pronounced inter-individual variability in phenotype. We generated and characterized transgenic SQT1 rabbits and investigated electrical remodelling. Methods and results: Transgenic rabbits were generated by oocyte-microinjection of β-myosin-heavy-chain-promoter-KCNH2/HERG-N588K constructs...
November 28, 2018: European Heart Journal
M A C Koole, D Kauw, M M Winter, D A J Dohmen, I I Tulevski, R de Haan, G A Somsen, M P Schijven, D Robbers-Visser, B J M Mulder, B J Bouma, M J Schuuring
BACKGROUND: Arrhythmias and heart failure are common and invalidating sequelae in adult patients with congenital heart disease (CHD). Mobile health (m-Health) enables daily monitoring and a timely response that might prevent deterioration. We present an observational prospective registry to evaluate feasibility of an m‑Health telemonitoring program for managing arrhythmia, heart failure and blood pressure in symptomatic adults with CHD. METHODS: Symptomatic adult patients with CHD are enrolled in an m‑Health telemonitoring program, which evaluates single-lead ECG, blood pressure and weight measurements...
November 28, 2018: Netherlands Heart Journal
Per Sundbom, Anne-Marie Suutari, Karim Abdulhadi, Wojciech Broda, Melinda Csegedi
Myocarditis is mostly caused by viral infections and rarely caused by bacterial pathogens, especially in immunocompetent individuals. Bacterial myocarditis due to Salmonella is rare, especially in countries with improved sanitation that minimize contamination of Salmonella typhi serotypes. We here present a case of a previous healthy 22-year-old male that came to the emergency room with chest pain. His symptoms occurred after a period of profuse diarrhea, fever and hematochezia. Magnetic resonance imaging confirmed the diagnosis of myocarditis...
December 2018: Oxford Medical Case Reports
Yahui Zhang, Zhihao Jiang, Lin Qi, Lisheng Xu, Xingguo Sun, Xinmei Chu, Yanling Liu, Tianjing Zhang, Stephen E Greenwald
Objective: This study aimed to compare differences in cardiorespiratory function between untreated hypertensive subjects (UHS) and healthy subjects (HS) during cardiopulmonary exercise testing (CPET). Additionally, it also aimed to explore the potential mechanisms of different exercise responses in cardiorespiratory function before, during and after CPET. Methods: Thirty subjects (15 UHS and 15 HS) were enrolled. Photoplethysmography (PPG), respiratory signal, and ECG were simultaneously collected while subjects were performing CPET...
2018: Frontiers in Physiology
John J Lazarus, Ashraf Saleh, Michael Ghannam, Keith Aaronson, Monica Colvin, Frank Pagani, Todd Koelling, James R Corbett, Richard L Weinberg, Venkatesh L Murthy, Matthew C Konerman
OBJECTIVES: We sought to determine the safety of regadenoson (REG) stress testing in patients who have undergone orthotopic heart transplantation (OHT). BACKGROUND: Routine screening for cardiac allograft vasculopathy (CAV) is necessary after OHT. Adenosine stress is contraindicated after heart transplantation due to supersensitivity in denervated hearts. Safety of regadenoson stress following OHT has not been well studied. METHODS: We retrospectively reviewed data from OHT patients (N = 123) who were referred to REG stress testing...
November 27, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Lucy C Beishon, Ronney B Panerai, Thompson G Robinson, Hari Subramaniam, Victoria J Haunton
Background: The incidence of dementia is predicted to rise rapidly, but sensitive diagnostic tests remain elusive. Changes in cerebral blood flow velocity (CBFv) can occur at an early stage of cognitive decline, and can be measured by transcranial Doppler ultrasonography (TCD). Objective: The aim of this study was to characterize the CBFv changes that occur in healthy older adults (HC), mild cognitive impairment (MCI), and Alzheimer's disease (AD), in response to a language task from the Addenbrooke's cognitive examination (ACE-III)...
September 28, 2018: JAD Reports
Radwa A Eladwy, Eman M Mantawy, Wesam M El-Bakly, Mohamed Fares, Laila A Ramadan, Samar S Azab
BACKGROUND: Lowbush blueberry extract (Vaccinium angustifolium) is abundant with polyphenols (such as chlorogenic acid) with high antioxidant profile. It has received great interest due to its protective role in many disorders such as heart diseases and neurological disorders. HYPOTHESIS: We hypothesized that blueberry leaf extract might have a protective effect against cardiac hypertrophy via suppressing oxidative stress, inflammation and fibrosis. METHOD: Blueberry leaf nutraceutical extract was administered orally to male albino rats at three different doses (25, 50 and 100 mg/kg/day of the extract, equivalent to 3...
December 1, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
Reka Dulandas, Petra Brysiewicz
Introduction: Emergency nurses are usually the first to interact with critically ill patients and victims of violence and injuries, and require advanced skills and knowledge to manage such patients. Inadequate training prevents nurses from providing optimal emergency care, and it is important to investigate if there are any skills and competencies lacking in these emergency nurses. We sought to describe the self-perceived educational needs of emergency nurses in Durban, South Africa. Methods: A descriptive quantitative survey was conducted with nurses working in four emergency centres (two state, and two privately funded hospitals) in Durban, South Africa...
September 2018: African Journal of Emergency Medicine Revue Africaine de la Médecine D'urgence
Maria Dolores Pelaez Coca, Maria Teresa Lozano Albalate, Alberto Hernando, Montserrat Aiger, Eduardo Gil
Our long-term goal is the development of an automatic identifier of attentional states. In order to accomplish it, we should firstly be able to identify different states based on physiological signals. So, the first aim of this work is to identify the most appropriate features, to detect a subject high performance state. For that, a database of electrocardiographic (ECG) and photopletysmographic (PPG) signals is recorded in two unequivocally defined states (rest and attention task) from up to 50 subjects as a sample of the population...
November 19, 2018: IEEE Journal of Biomedical and Health Informatics
C Yilmazer, M Cevik, A Kocyigit
The aim of this study was to compare the efficacy of estrus induction and fertility by using subcutaneous melatonin (MEL, T1) and short-term intravaginal medroxyprogesteronacetate plus pregnant mare serum gonadotropin treatments (sMAP+eCG, T2) in ewes on seasonaly anestrus. In this study, 105 mature clinically healthy Kivircik ewes in anestrus season and 4 rams were used. After synchronization applications, ewes exhibiting estrus signs were hand-mated with rams known to be fertile. Blood samples were collected at different times in order to determine progesterone (P4) concentrations...
June 2018: Polish Journal of Veterinary Sciences
Sook H Park, Ida T Fonkoue, Yunxiao Li, Dana R DaCosta, Holly R Middlekauff, Jeanie Park
Introduction: End-stage renal disease (ESRD) patients with a paradoxical increase in blood pressure (BP) during hemodialysis (HD), termed intradialytic hypertension (ID-HTN), are at significantly increased risk for mortality and adverse cardiovascular events. ID-HTN affects up to 15% of all HD patients, and the pathophysiologic mechanisms remain unknown. We hypothesized that ESRD patients prone to ID-HTN have heightened volume-sensitive cardiopulmonary baroreflex sensitivity (BRS) that leads to exaggerated increases in sympathetic nervous system (SNS) activation during HD...
November 2018: KI Reports
Jose Vicente, Robbert Zusterzeel, Lars Johannesen, Roberto Ochoa-Jimenez, Jay W Mason, Carlos Sanabria, Sarah Kemp, Philip T Sager, Vikram Patel, Murali K Matta, Jiang Liu, Jeffry Florian, Christine Garnett, Norman Stockbridge, David G Strauss
Balanced multi-ion channel-blocking drugs have low torsade risk because they block inward currents. The Comprehensive in vitro Proarrhythmia Assay (CiPA) initiative proposes to use an in-silico cardiomyocyte model to determine the presence of balanced block, and absence of J-Tpeakc prolongation would be expected for balanced blockers. This study included 3 balanced blockers in a 10-subject per drug parallel-design; lopinavir/ritonavir and verapamil met the primary endpoint of ΔΔJ-Tpeakc upper bound <10 ms, while ranolazine did not (upper bounds of 8...
November 17, 2018: Clinical Pharmacology and Therapeutics
Zhongxia Shang, Yang Zhao, Yong Lian
FIR filter is one of the best choices for ECG signal processing because of its linear phase property. With frequency response masking (FRM) technique, the multipliers needed to implement FIR filter can be reduced dramatically. This paper proposes an architecture for asymmetrical bandpass FIR filter based on the FRM technique. The optimum interpolation factor for the filter is derived and the design procedure for all the sub-filters is given. A design example is included to illustrate the effectiveness of the proposed filter for ECG signal processing...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Ming Liu, Younghoon Kim
Heart disease classification based on electrocardiogram(ECG) signal has become a priority topic in the diagnosis of heart diseases because it can be obtained with a simple diagnostic tool of low cost. Since early detection of heart disease can enable us to ease the treatment as well as save people's lives, accurate detection of heart disease using ECG is very important. In this paper, we propose a classification method of heart diseases based on ECG by adopting a machine learning method, called Long Short-Term Memory (LSTM), which is a state-of-the-art technique analyzing time series sequences in deep learning...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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