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Response to ECG

Midori Ohta, Takayuki Ueda, Kaoru Sakurai
The deterioration in masticatory function often seen in older adults rules out the consumption of hard foods, while a common decline in autonomic nervous response often observed in older adults may result in maladjustment to environmental stresses. The purpose of this study was to investigate whether autonomic nervous activity in older adults increased during the mastication of soft foods compared to at rest. The participants comprised 9 volunteer nursing home residents aged 78 to 100 years. All consumed soft rice as a grain dish and coarsely chopped food as side dishes...
October 18, 2018: Bulletin of Tokyo Dental College
Shuai Mao, Dan-Ping Xu, Xiao-Jing Dang, Winny Li, Huan-Lin Wu
BACKGROUND: Many patients with chronic angina experience anginal episodes despite successful recanalization, antianginal and antiischemic medications. Empirical observations suggested that Shenzhu Guanxin Recipe Granules (, SGR), a Chinese herbal compound, exerted potential impacts on increased treadmill exercise performance and angina relieve. However, there has been no systematic study to clarify the impact of SGR on exercise tolerance in patients with stable angina. The SERIES (ShEnzhu guanxin Recipe for Improving Exercise tolerance in patients with Stable angina) trial is designed to determine the effects of SGR on exercise duration, electrocardiographic (ECG) evidence of myocardial ischemia, and incidence of major adverse cardiac events (MACE) in stable anginal patients...
October 17, 2018: Chinese Journal of Integrative Medicine
Kahina Ghanem, A L Johnson
In laying hens, pre-recruitment ovarian follicles (1-8 mm diameter) are arranged as a continuum of size and predicted maturity. Cyclic recruitment of a pre-recruitment follicle to the preovulatory stage begins, in part, by the ability of the granulosa cell (GC) layer to initiate responsiveness to follicle stimulating hormone- (FSH-) induced cyclic adenosine monophosphate. The objective of this study was to determine if increased circulating concentrations of FSH during the ovulatory cycle increase the number of recruited follicles, in a dose-dependent manner...
October 12, 2018: General and Comparative Endocrinology
Elisabeth Kaiser, Qinghai Tian, Michael Wagner, Monika Barth, Wenying Xian, Laura Schroeder, Sandra Ruppenthal, Lars Kaestner, Ulrich Boehm, Philipp Wartenberg, Huiyan Lu, Sara M McMillin, Derek B Bone, Jürgen Wess, Peter Lipp
Aims: Signaling via Gq-coupled receptors is of profound importance in many cardiac diseases such as hypertrophy and arrhythmia. Nevertheless, owing to their widespread expression and the inability to selectively stimulate such receptors in vivo, their relevance for cardiac function is not well understood. We here use DREADD technology to understand the role of Gq-coupled signaling in vivo in cardiac function. Methods and Results: We generated a novel transgenic mouse line that expresses a Gq-coupled DREADD (Dq) in striated muscle under the control of the MCK promotor...
October 13, 2018: Cardiovascular Research
Tatiana Soares, Maria Claudia Irigoyen, Sílvia Goldmeier
BACKGROUND: The Medical Control Program for Occupational Health establishes the required supplementary exams, according to the activity exercised by the worker and its inherent risks. The Regulatory Norm No. 35, recently deployed, stipulates that at-height workers must undergo electrocardiogram exams as an additional routine examination. OBJECTIVE: To evaluate the electrocardiographic standard in at-height. METHODOLOGY: A cross-sectional study, developed from May 2014 to January 2015 with male at-height workers...
May 2018: Revista da Associação Médica Brasileira
Ida T Fonkoue, Seth D Norrholm, Paul J Marvar, Yunxiao Li, Melanie L Kankam, Barbara O Rothbaum, Jeanie Park
Posttraumatic stress disorder (PTSD) is characterized by increased sympathetic nervous system (SNS) activity, blunted parasympathetic nervous system (PNS) activity, and impaired baroreflex sensitivity (BRS) that contribute to accelerated cardiovascular disease (CVD). PTSD patients also have chronic stress-related elevations in resting blood pressure (BP), often in the prehypertensive range; yet, it is unclear if elevated resting blood pressure (ERBP) augments these autonomic derangements in PTSD. We hypothesized that compared to normotensive PTSD (N-PTSD), those with ERBP (E-PTSD) have further increased SNS, decreased PNS activity and impaired BRS at rest, and exaggerated SNS reactivity, PNS withdrawal, and pressor responses during stress...
October 10, 2018: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Caroline Hoad, Christopher Clarke, Luca Marciani, Martin John Graves, Maura Corsetti
Cine cardiac MRI is generally accepted as the 'gold-standard' for functional myocardial assessment. It only took a few years after the development of commercial MRI systems for functional cardiac imaging to be developed, with ECG gated cine imaging first reported in 1988. The function of the GI tract is more complex to study compared to the heart. However, the idea of having a non-invasive tool to study the GI function that also allows the concurrent assessment of different aspects of this function has become more and more attractive in the gastroenterological field...
October 9, 2018: British Journal of Radiology
A Chansaenroj, N Songsasen, K Chatdarong
Equine chorionic gonadotropin (eCG) has been commonly used to induce estrus in several felid species. However, the mechanisms by which this gonadotropin regulates cat folliculogenesis are still unclear. We investigated the responsiveness of cat ovarian follicles at different developmental stages to various eCG concentrations supplemented in vitro. Follicles were mechanically isolated from the ovaries of 22 cats and categorized into three developmental stages based on their morphology and diameter: 1) two-layered secondary follicle (SF), 100-150 μm (n = 139); 2) multi-layered SF, 150-300 μm (n = 154); and 3) early antral follicle (AF), ≥300-500 μm (n = 123)...
September 29, 2018: Theriogenology
Corina Aguilar-Raab, Marc N Jarczok, Marco Warth, Martin Stoffel, Friederike Winter, Maria Tieck, Judith Berg, Lobsang Tenzin Negi, Tim Harrison, Thaddeus W W Pace, Beate Ditzen
INTRODUCTION: Positive social interactions (PSIs) and stable relationships can exert substantial benefits on health. However, patients suffering from depression benefit less from these health-promoting effects. Moreover, relationship quality and even partners' health has been found to be negatively affected by depressive symptomatology, which may result in overall impairments in social functioning of a romantic couple. Psychobiological research indicates that these impairments may be accompanied by a maladaptive regulation of the patient's neuroendocrine response to external stressors...
October 4, 2018: BMJ Open
Jie Song, Linlin Qiao, Lizhen Ji, Baixiang Ren, Yongyuan Hu, Ruibin Zhao, Zongming Ren
The electrocardiogram (ECG) has been widely used to objectively address the physical condition as an index of stress. Though a numerous accounts of investigations on aquatic organisms' ECGs have been made, differentiation of ECG parameters in responding to specific toxic chemicals has not been extensively studied. In this research, it is hypothesized that zebrafish (Danio rerio) ECG parameters would differently respond to different types of pollutants, a heavy metal, thallium (Tl, 0.10 and 13.00 μg/L) and an organic chemical, deltamethrin (DM, 0...
December 2018: Chemosphere
Ole Elvebakk, Christian Tronstad, Kåre I Birkeland, Trond G Jenssen, Marit R Bjørgaas, Kathrine F Frøslie, Kristin Godang, Håvard Kalvøy, Ørjan G Martinsen, Hanne L Gulseth
People with type 1 diabetes and impaired awareness of hypoglycaemia (IAH) are prone to severe hypoglycaemia. Previous attempts to develop non-invasive hypoglycaemia alarm systems have shown promising results, but it is not known if such alarms can detect severe hypoglycaemia in people with IAH. We aimed to explore whether a combination of non-invasive sensors could reliably evaluate hypoglycaemia (plasma glucose (PG) minimum 2.5 mmol/L) in people with IAH. Twenty participants with type 1 diabetes and IAH underwent randomly ordered, single blinded hyperinsulinemic euglycaemic and hyperinsulinemic hypoglycaemic clamps...
October 3, 2018: Scientific Reports
Masaomi Chinushi, Hitoshi Tachikawa, Yuko Chinushi, Toshio Yamaguchi, Osamu Saitoh, Takashi Tsuda
In an 86-year-old woman who had been treated for sick sinus syndrome, the small high-frequency current delivered by pacemaker in order to measure the minutes ventilation for utilizing the rate-response mode was transiently over-sensed on the Holter electrocardiogram. Although her pacing system was working appropriately, the numbers of the paced beats on the automatic Holter analysis were undercounted (from >60% to <5%) during the over-sensing periods because these currents were recognized as multiple pacing spikes...
December 2017: Journal of Cardiology Cases
Alejandro Cruz Utrilla, Javier Higueras, Juan José González Ferrer
No abstract text is available yet for this article.
October 2018: Revista Española de Cardiología
V Tkachenko, Y Kovalchuk, N Bondarenko, О Bondarenko, G Ushakova, A Shevtsova
Heart diseases, especially acute coronary syndrome (ACS), are among the most severe illnesses that often lead to death. Despite significant advances in the prevention and treatment of ACS, the incidence of the disease and its complications are very serious. The imbalance between pro- and antioxidant systems, the formation of active carbonyl compounds, and the end products of glycation in the blood and tissues are the key moments in the development of heart and neurological disorders leading to a change of behavioral responses...
2018: Biochemistry Research International
Z R Cao, S M Cui, X X Lu, X M Chen, X Yang, J P Cui, G H Zhang
Objective: To investigate the effects of cadmium exposure on cardiovascular system of occupational workers. Methods: Cross-sectional study was applied to 992 workers in a nickel-cadmium battery plant in November, 2011, of which 749 were cadmium exposed workers and 243 were controls without cadmium and other expose. Urinary cadmium、electrocardiogram (ECG) and blood pressure were examined simultaneously among 992 workers. The risk factors of ECG abnormality rate and hypertension rate were analyzed by Logistic regression...
June 20, 2018: Chinese Journal of Industrial Hygiene and Occupational Diseases
Eberhard P Scholz, Patrick Fischer, Patrick Lugenbiel, Panagiotis Xynogalos, Patrick A Schweizer, Daniel Scherer, Dierk Thomas, Hugo A Katus, Edgar Zitron
PURPOSE: Left bundle branch block (LBBB) has a predictive value for response to cardiac resynchronization therapy as reported by Zareba et al. (Circulation 123(10):1061-1072, 2011). However, based on ECG criteria, the discrimination between complete LBBB and nonspecific intraventricular conduction delay is challenging. We tested the hypothesis that discrimination can be performed using standard electrophysiological catheters and a simple stimulation protocol. METHODS: Fifty-nine patients were analyzed retrospectively...
September 19, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Stephen J H Dobbin, Alan C Cameron, Mark C Petrie, Robert J Jones, Rhian M Touyz, Ninian N Lang
Clinical outcomes for patients with a wide range of malignancies have improved substantially over the last two decades. Tyrosine kinase inhibitors (TKIs) are potent signalling cascade inhibitors and have been responsible for significant advances in cancer therapy. By inhibiting vascular endothelial growth factor receptor (VEGFR)-mediated tumour blood vessel growth, VEGFR-TKIs have become a mainstay of treatment for a number of solid malignancies. However, the incidence of VEGFR-TKI-associated cardiovascular toxicity is substantial and previously under-recognised...
September 18, 2018: Heart: Official Journal of the British Cardiac Society
Taleb Askaripoor, Majid Motamedzadeh, Rostam Golmohammadi, Maryam Farhadian, Mohammad Babamiri, Mehdi Samavati
Fatigue and sleepiness are one of the main causes of human errors and accidents in the workplace. The empirical evidence has approved that, in addition to stimulating the visual system, light elicits brain responses, which affect physiological and neurobehavioral human functions, known as the non-image forming (NIF) effects of light. As recent evidences have shown the positive effects of red or low correlated color temperature white light on alertness and performance, we investigated whether exposure to 2564 K light could improve subjective and objective measures of alertness and performance compared with 7343 K, 3730 K, and dim light (DL) conditions during the daytime...
September 12, 2018: Journal of Circadian Rhythms
Taylor J Yaw, Marc S Kraus, Allison Ginsburg, Leigh A Clayton, Catherine A Hadfield, Anna R Gelzer
A bipolar, single-lead electrocardiogram (ECG) device is capable of recording ECGs with an integrated smartphone application. To determine the utility of this device, phone-based ECGs (pECG) were compared with standard six-lead ECGs (sECG) in four female Atlantic bottlenose dolphins ( Tursiops truncatus) at the National Aquarium. Study animals were trained to haul out onto a dry deck in ventral recumbency and allow simultaneous 30-sec ECG acquisition using the two devices. The pECG device was held against the thoracic wall caudal to the left axilla...
September 2018: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
Kim A Henderson, R Brandon Borders, John B Ross, Amir Abdulalil, Seth Gibbs, Anthony J Skowronek, Katherine Knostman, Jay Bailey, Jeremy Smith, Tom Vinci, Brandon Wood, Michael V Knopp, Brian M Roche
The isolated rat heart (Langendorff) assay combined with NMR spectroscopy and histology were used to elucidate functional, metabolic, and histological signs of cardiotoxicity resulting from acute exposure to clinically relevant concentrations of doxorubicin and its metabolite dox-ol. Doxorubicin blood concentrations and pharmacokinetic parameters were assessed following a clinically relevant dose of 2 mg/kg in order to select concentrations for isolated heart perfusions. Isolated rat hearts were exposed to 1 or 10 μM of doxorubicin or 0...
September 6, 2018: Journal of Pharmacological and Toxicological Methods
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