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Jinfeng Ding, Yunhe Zhao, Zhengqun Zhang, Chunmei Xu, Wei Mu
The black cutworm, Agrotis ipsilon (Hufnagel) (Lepidoptera: Noctuidae), has been considered a major insect pest in China that causes damage to corn at the seeding stage. The present study measured the lethal and sublethal effects of the neonicotinoid insecticide clothianidin on A. ipsilon. Clothianidin, incorporated using an artificial diet, exhibited signs of active toxicity on fourth-instar larvae of A. ipsilon, with a 50%-lethal concentration (LC50) of 27.77 µg/g. Clothianidin at the LC20 and LC40 levels impaired the normal development of A...
December 14, 2018: Journal of Economic Entomology
Mark E Pennesi, David G Birch, K Thiran Jayasundera, Maria Parker, Ou Tan, Rabia Gurses-Ozden, Carrie Reichley, Kathleen N Beasley, Paul Yang, Richard G Weleber, Lea D Bennett, John R Heckenlively, Kalyani Kothapalli, Jeffrey D Chulay, For The Xlrs-Study Group
Purpose: Prospective evaluation of patients with X-linked retinoschisis (XLRS). Methods: Fifty-six males XLRS patients, age ≥7 years, had retinal structure and function tests performed every 6 months during an 18-month period. Results: Best corrected visual acuity (BCVA) was abnormal (mean ± SD logMAR 0.57 ± 0.32 OD and 0.50 ± 0.27 OS), with weak correlation between visual acuity and age (R = -0.24, P = 0.0095). Mean cyst cavity volume (CCV) determined on optical coherence tomography showed weak correlation with age (R = -0...
December 3, 2018: Investigative Ophthalmology & Visual Science
Andrew R Pines, Mithun G Sattur, Karl R Abi-Aad, Bernard R Bendok
No abstract text is available yet for this article.
January 1, 2019: Neurosurgery
Jérôme Lavoué, Lawrence Joseph, Peter Knott, Hugh Davies, France Labrèche, Frédéric Clerc, Gautier Mater, Tracy Kirkham
Introduction: Interpretation of exposure measurements has evolved into a framework based on the lognormal distribution. Most available practical tools are based on traditional frequentist statistical procedures that do not satisfactorily account for censored data and are not amenable to simple probabilistic risk statements. Bayesian methods offer promising solutions to these challenges. Such methods have been proposed in the literature but are not widely and freely available to practitioners...
December 14, 2018: Annals of Work Exposures and Health
Emily R Jeffries, Michael J Zvolensky, Julia D Buckner
Introduction: Despite negative effects of smoking, smokers have difficulty quitting, suggesting a need for additional strategies to help them quit. A single-session hatha yoga intervention acutely reduced craving among nicotine-deprived smokers not attempting to reduce or quit, yet it is unknown if it reduces craving among those attempting to change their smoking. Thus, the current study tested the efficacy of a single-session hatha yoga intervention for acutely reducing craving among smokers attempting to reduce or quit smoking...
December 14, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
W Mengesha, R Steege, A Z Kea, S Theobald, D G Datiko
Background: Health extension workers (HEWs) are the key cadre within the Ethiopian Health Extension Programme extending health care to rural communities. National policy guidance supports the use of mHealth to improve data quality and use. We report on a mobile Health Management Information system (HMIS) with HEWs and assess its impact on data use, community health service provision and HEWs' experiences. Methodology: We used a mixed methods approach, including an iterative process of intervention development for 2 out of 16 essential packages of health services, quantitative analysis of new registrations, and qualitative research with HEWs and their supervisors...
December 1, 2018: Journal of Public Health
Luis H B Ferreira, Andre C Smolarek, Philip D Chilibeck, Marcelo P Barros, Steven R McAnulty, Brad J Schoenfeld, Bruna Amorim Zandona, Tácito P Souza-Junior
OBJECTIVES: It is well established that ingestion of sodium bicarbonate (NaHCO3 ) causes metabolic alkalosis. However, there is no consensus in terms of optimal NaHCO3 doses leading to enhanced performance. This study aimed to determine the effects of different NaHCO3 doses on performance and lactate clearance in non-professional cyclists. METHODS: Twenty-one cyclists performed the following three double-blind trials: 1) ingestion of 0.3 g · kg-1 body weight (BW) of placebo; 2) ingestion of 0...
October 13, 2018: Nutrition
Peter G Lawlor, Nicole A Rutkowski, Alistair R MacDonald, Mohammed T Ansari, Lindsey Sikora, Franco Momoli, Salmaan Kanji, David K Wright, Erin Rosenberg, Annmarie Hosie, Jose L Pereira, David Meagher, Jill Rice, John Scott, Shirley H Bush
CONTEXT: Based on the clinical care pathway of delirium in palliative care (PC), a published analytic framework (AF) formulated research questions in key domains and recommended a scoping review to identify evidence gaps. OBJECTIVES: To produce a literature map for key domains of the published AF: screening; prognosis and diagnosis; management and the health-related outcomes. METHODS: A standard scoping review framework was used by an interdisciplinary study team of nurse and physician delirium researchers, an information specialist and review methodologists to conduct the review...
December 11, 2018: Journal of Pain and Symptom Management
V Svolos, R Hansen, B Nichols, C Quince, U Z Ijaz, R T Papadopoulou, C A Edwards, D Watson, A Alghamdi, A Brejnrod, C Ansalone, H Duncan, L Gervais, R Tayler, J Salmond, D Bolognini, R Klopfleisch, D R Gaya, S Milling, R K Russell, K Gerasimidis
BACKGROUND & AIMS: Exclusive enteral nutrition (EEN) is the only established dietary treatment for Crohn's disease (CD), but its acceptability is limited. There is a need for novel dietary treatments for CD. METHODS: We evaluated the effects of an individualized, food-based diet (CD-TREAT), with similar composition to EEN, on the gut microbiome, inflammation and clinical response in a rat model, healthy adults, and children with relapsing CD. Twenty-five healthy adults randomly received EEN or CD-TREAT for 7 days, followed by a 14-day washout period, followed by the alternate diet...
December 11, 2018: Gastroenterology
Bruno L Marques, Gustavo A Carvalho, Elis M M Freitas, Raphaela Chiareli, Thiago G Barbosa, Armani G P Di Araújo, Yanley L Nogueira, Raul I Ribeiro, Ricardo C Parreira, Mariana S Vieira, Rodrigo R Resende, Renato S Gomez, Onésia C Oliveira-Lima, Mauro C X Pinto
Stroke consists of an abrupt reduction of cerebral blood flow resulting in hypoxia that triggers an excitotoxicity, oxidative stress, and neuroinflammation. After the ischemic process, neural precursor cells present in the subventricular zone of the lateral ventricle and subgranular zone of the dentate gyrus proliferate and migrate towards the lesion, contributing to the brain repair. The neurogenesis is induced by signal transduction pathways, growth factors, attractive factors for neuroblasts, transcription factors, pro and anti-inflammatory mediators and specific neurotransmissions...
December 11, 2018: Seminars in Cell & Developmental Biology
Priya S Shah, Nichole Link, Gwendolyn M Jang, Phillip P Sharp, Tongtong Zhu, Danielle L Swaney, Jeffrey R Johnson, John Von Dollen, Holly R Ramage, Laura Satkamp, Billy Newton, Ruth Hüttenhain, Marine J Petit, Tierney Baum, Amanda Everitt, Orly Laufman, Michel Tassetto, Michael Shales, Erica Stevenson, Gabriel N Iglesias, Leila Shokat, Shashank Tripathi, Vinod Balasubramaniam, Laurence G Webb, Sebastian Aguirre, A Jeremy Willsey, Adolfo Garcia-Sastre, Katherine S Pollard, Sara Cherry, Andrea V Gamarnik, Ivan Marazzi, Jack Taunton, Ana Fernandez-Sesma, Hugo J Bellen, Raul Andino, Nevan J Krogan
Mosquito-borne flaviviruses, including dengue virus (DENV) and Zika virus (ZIKV), are a growing public health concern. Systems-level analysis of how flaviviruses hijack cellular processes through virus-host protein-protein interactions (PPIs) provides information about their replication and pathogenic mechanisms. We used affinity purification-mass spectrometry (AP-MS) to compare flavivirus-host interactions for two viruses (DENV and ZIKV) in two hosts (human and mosquito). Conserved virus-host PPIs revealed that the flavivirus NS5 protein suppresses interferon stimulated genes by inhibiting recruitment of the transcription complex PAF1C and that chemical modulation of SEC61 inhibits DENV and ZIKV replication in human and mosquito cells...
December 13, 2018: Cell
Oliver Bärenbold, Amadou Garba, Daniel G Colley, Fiona M Fleming, Ayat A Haggag, Reda M R Ramzy, Rufin K Assaré, Edridah M Tukahebwa, Jean B Mbonigaba, Victor Bucumi, Biruck Kebede, Makoy S Yibi, Aboulaye Meité, Jean T Coulibaly, Eliézer K N'Goran, Louis-Albert Tchuem Tchuenté, Pauline Mwinzi, Jürg Utzinger, Penelope Vounatsou
BACKGROUND: Intervention guidelines against Schistosoma mansoni are based on the Kato-Katz technique. However, Kato-Katz thick smears show low sensitivity, especially for light-intensity infections. The point-of-care circulating cathodic antigen (POC-CCA) is a promising rapid diagnostic test detecting antigen output of living worms in urine and results are reported as trace, 1+, 2+, and 3+. The use of POC-CCA for schistosomiasis mapping, control, and surveillance requires translation of the Kato-Katz prevalence thresholds into POC-CCA relative treatment cut-offs...
December 14, 2018: PLoS Neglected Tropical Diseases
Ebrahim S Elborgy, Matthew R Starr, Jacek G Kotowski, Jackson E Abou Chehade, Raymond Iezzi
PURPOSE: To report visual and anatomical outcomes after the repair of chronic idiopathic macular holes (MHs) with no face-down positioning. METHODS: We conducted a retrospective review of chronic MH cases of greater than 1-year duration that were repaired through pars plana vitrectomy with broad internal limiting membrane peeling and no face-down positioning between March 2009 and December 2017. There were 18 eyes of 18 patients that met inclusion criteria. Patients with MH duration of less than 1 year and without at least 1 month of follow-up were excluded...
December 6, 2018: Retina
M R Nagaraja, Satya Prakash Gubbala, C R Wilma Delphine Silvia, Ramars Amanchy
We aimed to survey the monogenic causes of disorders of sex development (DSD) and thereby its prevalence in India. This study revealed mutations resulting in androgen insensitivity syndrome, 5α-reductase type 2 deficiency, and gonadal dysgenesis were commonly reported. Intriguingly, AR deficits were the most prevalent (32 mutations) and of 11/26 missense mutations were in exons 4-8 (encoding ligand binding domain). The unique features of SRD5A2 defects were p.R246Q (most prevalent) and p.G196S could be mutational hotspots, dual gene defects (p...
December 14, 2018: Systems Biology in Reproductive Medicine
Benedek Kurdi, Allison E Seitchik, Jordan R Axt, Timothy J Carroll, Arpi Karapetyan, Neela Kaushik, Diana Tomezsko, Anthony G Greenwald, Mahzarin R Banaji
Using data from 217 research reports (N = 36,071, compared to 3,471 and 5,433 in previous meta-analyses), this meta-analysis investigated the conceptual and methodological conditions under which Implicit Association Tests (IATs) measuring attitudes, stereotypes, and identity correlate with criterion measures of intergroup behavior. We found significant implicit-criterion correlations (ICCs) and explicit-criterion correlations (ECCs), with unique contributions of implicit (β = .14) and explicit measures (β = ...
December 13, 2018: American Psychologist
Y DI, R L Yu, H DU, L Li, W J Yan, J G Liu, X Y Wang, J S Yin
Objective: To investigate the incidence of plant food allergy in patients with pollinosis and the effect of food allergens on the clinical symptoms of pollinosis patients. Method: A total of 40 patients with pollinosis and food allergy attended to the allergy Department of Duolun People's Hospital of Inner Mongolia were accepted skin prick test of inhaled allergens while the rhino conjunctivitis quality of life questionnaire(RQLQ) were also completed. The patients were divided into A and B groups randomly. Patients in group A were required for avoiding allergic plant foods intake but not them in group B...
December 5, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Y J Ji, Y F An, J M Xue, Q F Li, R Hou, Y T Zhang, X P Qi, Q Li, Z G Geng, F L Cheng, C Q Zhao
Objective: To explore the clinical efficacy of unilateral vidian neurectomy following endoscopic trans-sphenoethmoidal recess approach in treating allergic rhinitis. Method: The clinical data of 80 patients with moderate-severe allergic rhinitis who underwent unilateral vidian neurectomy following endoscopic trans-sphenoethmoidal recess approach were reviewed retrospectively. Visual analogue scale(VAS) was used to assess total symptom scores and nasal symptoms including nasal itching, nasal sneezing, rhinorrhea and nasal congestion...
October 5, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
G H Yang, D M Han, H R Zang, T Wang, L F Li
Objective: The aim of this study is to investigate the effect of polyethylene glycol acrylate hybrid hydrogel degradation substance on nasal mucociliary transport system. Method: In our experiment, the complex hydrogel were formed by the combination of different ratios of polyethyleneglycol diacrylate, chitosan and polyvinyl alcohol. The experiment was divided into four groups according to the international standard of medical devices. DMEM/F12∶BEGM culture medium was used for each packing material extraction, DMEM/F12∶BEGM culture medium was used as control...
December 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
S G Mardanly, V A Arsenieva, S S Mardanly, S V Rotanov, E A Amelina
The new original national set of reagents "Line-Blot human herpesvirus-profle" was developed to detect antibodies (IgG - set 1 and IgM - set 2) to main agents of herpesvirus infections (HSV-1, HSV-2, VZV, EBV, CMV) in the format of linear immunoblotting. The preliminary clinical trials were implemented using 319 samples of blood serum: HIV-infected patients (n=128), pregnant women (n=86) and persons undergoing treatment or diagnostic examination (n=105). In the case of every infection agent analyzes were implemented using enzyme-linked immunosorbent assay and linear immunoblotting with new set and its analogues of German manufacturer...
2018: Klinicheskaia Laboratornaia Diagnostika
R Paredes-Vázquez, D E Avitia-Enríque, A Castellanos-Alfaro, C G Chavajay-Cox
The fracture dislocation of the hip is a rare lesion described up to 4 to 17% of the cases and usually secondary to automobile accidents. Generally of poor prognosis and with already well documented complications such as avascular necrosis of the femoral head, osteoarthritis and heterotopic ossification. The iatrogenic fracture of the neck or head of the proximal femur is a complication even more rare and is not documented its incidence in the world literature. Having as probable causes the irreducibility of a dislocation of hip, more than one attempt of closed reduction, inadequate technique and some problems with the anesthesia and relaxation of the patient...
July 2018: Acta Ortopédica Mexicana
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