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https://www.readbyqxmd.com/read/30032686/healthcare-utilization-and-costs-with-fixed-source-versus-variable-source-tacrolimus-in-patients-receiving-a-kidney-transplant
#1
Suvapun Bunniran, Edward Lee, Pravin Kamble, Brandon Suehs, Billy Franks, Jason Schwartz, Gary Thal, James Spalding
AIMS: Switching drug manufacturers in transplant patients may require an increased intensity of therapeutic monitoring leading to additional healthcare visits, associated laboratory tests, and perhaps hospitalizations. As real-world studies examining the interchangeability of tacrolimus from different manufacturers are limited, the purpose of this study was to examine the healthcare resource utilization (HRU) and economic impact of tacrolimus-switching in kidney transplantation. MATERIALS AND METHODS: This cross-sectional, retrospective study examined HRU and healthcare costs (HCCs) among patients with a kidney transplant who were prescribed tacrolimus from fixed-source (FS) versus variable-source (VS) manufacturers using claims data from the large US health plan Humana from October 1, 2012, to December 31, 2013...
July 23, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/30027217/observational-outcomes-of-initial-trabeculectomy-with-mitomycin-c-in-patients-of-african-descent-vs-patients-of-european-descent-five-year-results
#2
Andrew H Nguyen, Nima Fatehi, Pablo Romero, Arezoo Miraftabi, EunAh Kim, Esteban Morales, JoAnn Giaconi, Anne L Coleman, Simon K Law, Joseph Caprioli, Kouros Nouri-Mahdavi
Importance: There is evidence that patients of African descent (AD) experience higher surgical failure rate after trabeculectomy without antimetabolites. Objective: To compare outcomes of initial trabeculectomy with mitomycin C in AD patients with those of patients of European descent (ED) and to identify prognostic factors for failure. Design, Setting, and Participants: In this retrospective matched cohort study, 135 eyes of 105 AD patients were matched with 135 eyes of 117 ED patients by age (within 5 years), surgeon, lens status, and follow-up time (within 1 year) from a single tertiary academic center...
July 19, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/30001765/comparison-of-unmanned-aerial-vehicle-technology-assisted-triage-versus-standard-practice-in-triaging-casualties-by-paramedic-students-in-a-mass-casualty-incident-scenario
#3
Trevor Jain, Aaron Sibley, Henrik Stryhn, Ives Hubloue
IntroductionThe proliferation of unmanned aerial vehicle (UAV) technology has the potential to change the way medical incident commanders (ICs) respond to mass-casualty incidents (MCIs) in triaging victims. The aim of this study was to compare UAV technology to standard practice (SP) in triaging casualties at an MCI. METHODS: A randomized comparison study was conducted with 40 paramedic students from the Holland College Paramedicine Program (Charlottetown, Prince Edward Island, Canada)...
July 13, 2018: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/29953079/-late-results-of-phaco-canaloplasty-in-patients-with-concomitant-advanced-pseudoexfoliation-glaucoma-and-cataract
#4
J V Hasanov, E M Kasimov
PURPOSE: To assess the safety and efficacy of phaco-canaloplasty in patients with concomitant advanced pseudoexfoliation glaucoma and cataract. MATERIAL AND METHODS: The study included 56 patients (57 eyes) who underwent phacoanaloplasty guided by Glaucolight microcatheter. All patients were followed up for 48 months. Visual acuity, changes of intraocular pressure (IOP), use of glaucoma medications, incidence of complications, as well as postsurgical interventions were examined...
2018: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29951182/a-framework-of-rebalancing-imbalanced-healthcare-data-for-rare-events-classification-a-case-of-look-alike-sound-alike-mix-up-incident-detection
#5
Yang Zhao, Zoie Shui-Yee Wong, Kwok Leung Tsui
Identifying rare but significant healthcare events in massive unstructured datasets has become a common task in healthcare data analytics. However, imbalanced class distribution in many practical datasets greatly hampers the detection of rare events, as most classification methods implicitly assume an equal occurrence of classes and are designed to maximize the overall classification accuracy. In this study, we develop a framework for learning healthcare data with imbalanced distribution via incorporating different rebalancing strategies...
2018: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29805392/first-aid-facilities-in-the-school-settings-are-schools-able-to-manage-adequately
#6
Farhan Muhammad Qureshi, Nadia Khalid, Seema Nigah-E-Mumtaz, Tahira Assad, Khola Noreen
Background and Objective: Children spend most of their time in schools and are vulnerable to injuries and mild ailments, hence requiring first-aid care. School teacher can provide immediate first-aid care in the absence of any health professional. This study assesses first-aid facilities within school premises and assessment of teachers on first aid training. Methods: A cross sectional study was conducted from July-December 2017, participants were full time school teachers of both public and private sectors at both primary and secondary levels, having a minimum of one year experience...
March 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29762887/the-underreporting-of-medication-errors-a-retrospective-and-comparative-root-cause-analysis-in-an-acute-mental-health-unit-over-a-3-year-period
#7
Maeve Morrison, Vicki Cope, Melanie Murray
Medication errors remain a commonly reported clinical incident in health care as highlighted by the World Health Organization's focus to reduce medication-related harm. This retrospective quantitative analysis examined medication errors reported by staff using an electronic Clinical Incident Management System (CIMS) during a 3-year period from April 2014 to April 2017 at a metropolitan mental health ward in Western Australia. The aim of the project was to identify types of medication errors and the context in which they occur and to consider recourse so that medication errors can be reduced...
May 15, 2018: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/29754685/-the-nurse-in-the-organisation-of-medical-assistance-on-board-a-ship
#8
Fabien Lefebvre, Benjamin Baudin, Antoine Bronstein, Hugues Lefort, Frank Peduzzi
Nursing practice on a ship involves certain risks and constraints inherent to the facilities themselves and the maritime environment. The response in the case of a medical incident at sea is guided by an organisation adapted to these constraints, overseen by a specific regulatory body. Different entities, players and resources may be involved depending on the diverse situations encountered.
May 2018: Revue de L'infirmière
https://www.readbyqxmd.com/read/29754594/review-of-medication-errors-that-are-new-or-likely-to-occur-more-frequently-with-electronic-medication-management-systems
#9
Melita Van de Vreede, Anne McGrath, Jan de Clifford
Objective. The aim of the present study was to identify and quantify medication errors reportedly related to electronic medication management systems (eMMS) and those considered likely to occur more frequently with eMMS. This included developing a new classification system relevant to eMMS errors. Methods. Eight Victorian hospitals with eMMS participated in a retrospective audit of reported medication incidents from their incident reporting databases between May and July 2014. Site-appointed project officers submitted deidentified incidents they deemed new or likely to occur more frequently due to eMMS, together with the Incident Severity Rating (ISR)...
May 14, 2018: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/29667565/longitudinal-associations-between-different-dementia-diagnoses-and-medication-use-jointly-accounting-for-dropout
#10
George O Agogo, Christine M Ramsey, Danijela Gnjidic, Daniela C Moga, Heather Allore
ABSTRACTBackground:Longitudinal studies of older adults are characterized by high dropout rates, multimorbid conditions, and multiple medication use, especially proximal to death. We studied the association between multiple medication use and incident dementia diagnoses including Alzheimer's disease (AD), vascular dementia (VD), and Lewy-body dementia (LBD), simultaneously accounting for dropout. METHODS: Using the National Alzheimer's Coordinating Center data with three years of follow-up, a set of covariate-adjusted models that ignore dropout was fit to complete-case data, and to the whole-cohort data...
April 18, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/29611607/the-epidemiology-of-operations-performed-by-the-national-sea-rescue-institute-of-south-africa-over-a-5-year-period
#11
Elaine Erasmus, Cleeve Robertson, Daniel Jacobus van Hoving
BACKGROUND: Injuries remain a major contributor of morbidity and mortality worldwide, with drowning accounting for 7% of all injury-related deaths with rates of between 4 and 8 per 100,000. The African region has death rates comparable to most low-income countries. Non-fatal drowning in Africa remains unquantified but it is estimated to be ten times higher than the fatal drowning rate. Timely search and rescue, initial resuscitation and rapid transportation to definitive care play a crucial role in preventing injury- related morbidity and mortality...
2018: International Maritime Health
https://www.readbyqxmd.com/read/29602960/impact-of-same-session-trabectome-surgery-on-ahmed-glaucoma-valve-outcomes
#12
Hamed Esfandiari, Tarek Shazly, Priyal Shah, Kiana Hassanpour, Pooya Torkian, Mehdi Yaseri, Nils A Loewen
PURPOSE: To evaluate the efficacy and survival rates of same session ab interno trabeculectomy with the trabectome and Ahmed glaucoma valve implant (AT) in comparison to the Ahmed glaucoma valve alone (A). METHOD: A total of 107 eyes undergoing primary glaucoma surgery were enrolled in this retrospective comparative case series, including 48 eyes which underwent AT and 59 eyes which received A alone. Participants were identified using the procedural terminology codes, and their medical records were reviewed...
August 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29575446/medication-safety-challenges-in-primary-care-nurses-perspective
#13
Hanan Khalil, Sarah Lee
AIMS AND OBJECTIVES: To identify the issues surrounding medication error reporting in community nursing and improvement strategies related to medication safety. BACKGROUND: Medication-related problems have been identified from various sources in the literature. Examples of these include incident reporting by healthcare professionals, medico-legal and patient complaints and systematic identification of organisational structure. Only a few studies report on the clinicians' perceptions of medication safety in community nursing and the challenges they face within their workplace to implement medication safety initiatives...
May 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29533324/the-effectiveness-of-a-comprehensive-wellness-assessment-on-medication-adherence-in-a-medicare-advantage-plan-diabetic-population
#14
Barbara Guerard, Vincent Omachonu, Blake Perez, Bisakha Sen
The issue of medication nonadherence has generated significant interest because of its complexity from both cost and outcomes perspectives. Of the 3.2 billion prescriptions written annually in the United States, estimates indicate that half are not taken as prescribed, especially among patients with asymptomatic chronic conditions. The objective of this study was to assess whether a comprehensive wellness assessment (CWA) program helps improve medication adherence for oral diabetic medications, statins, and angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers (ACE/ARBs) in a Medicare Advantage (MA) plan diabetic population...
March 2018: Journal of Healthcare Management / American College of Healthcare Executives
https://www.readbyqxmd.com/read/29516125/medical-speciality-medication-or-skills-key-factors-of-prehospital-joint-reduction-a-prospective-multicenter-cohort-study
#15
Georg Siebenbürger, Christian Zeckey, Julian Fürmetz, Wolfgang Böcker, Tobias Helfen
PURPOSE: Joint dislocations occur frequently in prehospital settings. The medical specialities of emergency physicians are heterogeneous. Decision making and the success rates of reduction attempt can vary greatly. The aim of this prospective multicentre study was to identify the factors most crucial for achieving successful prehospital reduction. METHODS: Study was conducted from 05/2012-05/2015 investigating cases of shoulder, patella and ankle joint dislocations in 16 emergency physician rescue stations...
March 7, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29329559/simplification-of-medications-prescribed-to-long-term-care-residents-simpler-study-protocol-for-a-cluster-randomised-controlled-trial
#16
Janet K Sluggett, Esa Y H Chen, Jenni Ilomäki, Megan Corlis, Sarah N Hilmer, Jan Van Emden, Choon Ean Ooi, Kim-Huong Nguyen, Tracy Comans, Michelle Hogan, Tessa Caporale, Susan Edwards, Lyntara Quirke, Allan Patching, J Simon Bell
BACKGROUND: Complex medication regimens are highly prevalent in residential aged care facilities (RACFs). Strategies to reduce unnecessary complexity may be valuable because complex medication regimens can be burdensome for residents and are costly in terms of nursing time. The aim of this study is to investigate application of a structured process to simplify medication administration in RACFs. METHODS: SImplification of Medications Prescribed to Long-tErm care Residents (SIMPLER) is a non-blinded, matched-pair, cluster randomised controlled trial of a single multidisciplinary intervention to simplify medication regimens...
January 12, 2018: Trials
https://www.readbyqxmd.com/read/29322597/the-implementation-of-a-successful-medication-safety-program-in-a-primary-care
#17
Hanan Khalil, Sarah Lee
RATIONALE, AIMS, AND OBJECTIVES: Improving patient safety is now a government priority in many economically developed and underdeveloped countries. Various medication safety interventions and programs that have been described in the literature focus on hospital settings, and only very few studies report on the implementation of such interventions in primary care. The main objectives of this study were firstly to describe the steps involved for the successful implementation of a medication safety program in primary care in rural Australia and secondly to report on its evaluation and provide recommendations for future initiatives...
April 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29169925/heat-stress-incidence-and-matchplay-characteristics-in-women-s-grand-slam-tennis
#18
Matthew T Smith, Machar Reid, Stephanie Kovalchik, Tim Wood, Rob Duffield
OBJECTIVES: To explore the relationship of wet bulb globe temperature (WBGT) on heat-related incidents and alterations in matchplay and behavioural characteristics in women's tennis at the Australian Open. DESIGN: From 360 main draw Australian Open women's matches (2014-2016), data describing on-court calls for trainers, doctors, cooling devices and water, post match medical consults and matchplay characteristics were collated. METHODS: Data were referenced against estimated WBGT and categorised into standard zones (zone 5: >32...
July 2018: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29095654/incidence-of-type-2-diabetes-mellitus-and-hyperlipidemia-in-patients-prescribed-dasatinib-or-nilotinib-as-first-or-second-line-therapy-for-chronic-myelogenous-leukemia-in-the-us
#19
Meg Franklin, Leah Burns, Samuel Perez, Deepak Yerragolam, Dinara Makenbaeva
OBJECTIVE: Evaluate the incidence of type 2 diabetes mellitus (T2DM) and hyperlipidemia (HLD) in CML patients initiating therapy with dasatinib or nilotinib. METHODS: Retrospective study using MarketScan claims from January 2006 to December 2014. The first analysis evaluated occurrence of T2DM, defined as ≥2 claims with a T2DM ICD-9 code or 1 diagnosis claim and an antidiabetic medication. The second analysis evaluated occurrence of HLD, defined as ≥2 claims with an HLD ICD-9 code, or 1 diagnosis claim and an anti-HLD medication...
February 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29039373/disepi-compact-visualization-as-a-tool-for-applied-epidemiological-research
#20
Arriel Benis, Moshe Hoshen
Outcomes research and evidence-based medical practice is being positively impacted by proliferation of healthcare databases. Modern epidemiologic studies require complex data comprehension. A new tool, DisEpi, facilitates visual exploration of epidemiological data supporting Public Health Knowledge Discovery. It provides domain-experts a compact visualization of information at the population level. In this study, DisEpi is applied to Attention-Deficit/Hyperactivity Disorder (ADHD) patients within Clalit Health Services, analyzing the socio-demographic and ADHD filled prescription data between 2006 and 2016 of 1,605,800 children aged 6 to 17 years...
2017: Studies in Health Technology and Informatics
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