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Hemoglobin variability hemodialysis

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https://www.readbyqxmd.com/read/30097326/association-of-circulatory-iron-deficiency-with-an-enlarged-heart-in-patients-with-end-stage-kidney-disease
#1
Toshihide Hayashi, Yuri Tanaka, Masaki Iwasaki, Hiroki Hase, Hiroyuki Yamamoto, Yasuhiro Komatsu, Ryoichi Ando, Masato Ikeda, Daijo Inaguma, Toshifumi Sakaguchi, Toshio Shinoda, Fumihiko Koiwa, Shigeo Negi, Toshihiko Yamaka, Takashi Shigematsu, Nobuhiko Joki
OBJECTIVES: High prevalence of iron deficiency (ID) and cardiomyopathy have been observed in patients with end-stage kidney disease (ESKD). Our objective was to clarify associations between ID and cardiac remodeling in patients with ESKD. DESIGN AND METHODS: A cross-sectional study was conducted using 1974 Japanese patients with ESKD at the initiation of maintenance dialysis. Levels of hemoglobin (Hb), iron status, and cardiac enlargement as assessed by the cardiothoracic ratio (CTR) were determined immediately before the first hemodialysis session...
August 7, 2018: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/30089568/cardiac-rhythm-disturbances-in-hemodialysis-patients-early-detection-using-an-implantable-loop-recorder-and-correlation-with-biological-and-dialysis-parameters
#2
Frederic Sacher, Laurence Jesel, Claire Borni-Duval, Valerie De Precigout, Frédéric Lavainne, Jean-Philippe Bourdenx, Atman Haddj-Elmrabet, Bruno Seigneuric, Adrien Keller, Julien Ott, Helene Savel, Yahsou Delmas, Dorothée Bazin-Kara, Nicolas Klotz, Sylvain Ploux, Sébastien Buffler, Philippe Ritter, Virginie Rondeau, Pierre Bordachar, Claire Martin, Antoine Deplagne, Sylvain Reuter, Michel Haissaguerre, Jean-Baptiste Gourraud, Cécile Vigneau, Philippe Mabo, Philippe Maury, Thierry Hannedouche, Antoine Benard, Christian Combe
OBJECTIVES: The aim of this study was to identify using implantable loop recorder (ILR) monitoring the mechanisms leading to sudden death (SD) in patients undergoing hemodialysis (HD). BACKGROUND: SD accounts for 11% to 25% of death in HD patients. METHODS: Continuous rhythm monitoring was performed using the remote monitoring capability of the ILR device in patients undergoing HD at 8 centers. Clinical, biological, and technical HD parameters were recorded and analyzed...
March 2018: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/30080914/evaluation-of-variables-associated-with-the-patency-of-arteriovenous-fistulas-for-hemodialysis-created-by-a-nephrologist
#3
Anderson Tavares Rodrigues, Fernando Antônio Basile Colugnati, Marcus Gomes Bastos
INTRODUCTION: Arteriovenous fistula (AVF) is considered the gold standard vascular access for chronic hemodialysis, and its failure predicts higher morbidity and mortality rates. OBJECTIVE: 1) To evaluate the success rate of AVF created by a nephrologist and 2) to identify clinical, laboratory, and demographic variables that influence AVF patency. METHODS: A retrospective cohort study of 101 patients with chronic kidney disease for a total of 159 AVF created by a nephrologist between June 2010 and June 2013...
August 2, 2018: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/30063696/association-of-dose-and-frequency-on-the-survival-of-patients-on-maintenance-of-hemodialysis-in-china-a-kaplan-meier-and-cox-proportional-hazard-model-analysis
#4
Yan Sun, Yankui Wang, Wenhong Yu, Yan Zhuo, Qian Yuan, Xiongfei Wu
BACKGROUND Dialysis frequency and dose are controversial prognostic factors of hemodialysis morbidity and mortality. The aim of this study was to find out the effect of frequency and dosage of dialysis on mortality and survival in a group of Chinese hemodialysis patients. MATERIAL AND METHODS In total, 183 patients seen from February 2008 to January 2018, who were on maintenance hemodialysis for at least 3 months, were included in the study cohort. An anonymized database of age, gender, diabetic status, comorbidities, date of initiation of dialysis, hematological characters, biochemical variables, and status of survived or died was established from DICOM (Digital Imaging and Communications in Medicine) files of patients...
July 31, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/30049300/individualized-anemia-management-in-a-dialysis-facility-long-term-utility-as-a-single-center-quality-improvement-experience
#5
Adam E Gaweda, Alfred A Jacobs, George R Aronoff, Michael E Brier
BACKGROUND: Standard protocol-based approaches to erythropoiesis stimulating agent (ESA) dosing in anemia management of end-stage renal disease (ESRD) fail to address the inter-individual variability in patient's response to ESA. We conducted a single-center quality improvement project to investigate the long-term performance of a computer-designed dosing system. MATERIALS AND METHODS: The study was a retrospective case-control study with long-term follow-up. All hemodialysis patients who received treatment at University Kidney Center (Louisville, KY, USA) between September 1, 2009, and March 31, 2017, were included...
July 27, 2018: Clinical Nephrology
https://www.readbyqxmd.com/read/29974406/impact-of-hemoglobin-variability-on-cardiovascular-mortality-in-maintenance-hemodialysis-patients
#6
Fu-Jun Lin, Xi Zhang, Lu-Sheng Huang, Gang Ji, Hai-Dong Huang, Yun Xie, Geng-Ru Jiang, Xin Zhou, Wei Lu
PURPOSE: Although the association between anemia and cardiovascular mortality in hemodialysis patients is well established, whether hemoglobin variability (Hgb-Var) affects the prognosis remains unclear. We aimed to evaluate the association between Hgb-Var and cardiovascular mortality in Chinese hemodialysis patients. METHODS: This retrospective study included 252 patients starting hemodialysis in Xin Hua Hospital between January 2009 and December 2015. Patients were divided into three tertiles based on Hgb-Var, as reflected by SD Hgbmean , SD Hgbrange , and Hgbdeflection during a 12-month evaluation period after hemodialysis initiation...
July 4, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29946818/effect-of-frequency-of-intravenous-iron-administration-on-hemoglobin-variability-in-maintenance-hemodialysis-patients
#7
Li Wan, Dongliang Zhang
TARGET: To observe the effect on hemoglobin (Hb) variability with different treatment frequencies of intravenous iron in maintenance hemodialysis (MHD) patients. METHODS: There were 41 MHD patients enrolled in the cohort. The patients were separated into two groups randomly. The baseline data were collected after oral iron agents for 1 month (wash out). There were two methods of intravenous iron administration, either continuous or intermittent. For continuous administration (CA), 100 mg sucrose iron agents were given during every HD session with total dose of 1000 mg...
August 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29945128/patterns-of-erythropoiesis-stimulating-agent-use-in-european-hemodialysis-patients-the-dialysis-outcomes-and-practice-patterns-study
#8
Douglas S Fuller, Bruce M Robinson, Francesco Locatelli, Ronald L Pisoni
BACKGROUND: Clinicians providing dialysis care have numerous erythropoiesis-stimulating agents (ESAs) available for treating anemia. We sought to provide a contemporary description of ESA types used in hemodialysis (HD) settings in nine European countries. METHODS: Our study uses Dialysis Outcomes and Practice Patterns Study phase 5 (2012-2015) data from nine European countries (Belgium, France, -Germany, Italy, Russia, Spain, Sweden, Turkey, and the United Kingdom)...
June 26, 2018: Nephron
https://www.readbyqxmd.com/read/29805324/factors-influencing-hemoglobin-variability-and-its-association-with-mortality-in-hemodialysis-patients
#9
Zeynep Bal, Bahar Gurlek Demirci, Suleyman Karakose, Emre Tutal, Mehtap Erkmen Uyar, Nurhan Ozdemir Acar, Siren Sezer
Purpose: We aimed to investigate the factors influencing hemoglobin variability with inflammatory and nutritional parameters and its associations with all-cause mortality among hemodialysis patients. Methods: One hundred and sixty-nine patients during the entire 12 months were enrolled into the study. Fasting plasma glucose, creatinine, calcium, phosphorus, alkaline phosphatase, parathyroid hormone (PTH), C-reactive protein (CRP), serum iron, serum iron-binding capacity, and transferrin saturation were analyzed...
2018: TheScientificWorldJournal
https://www.readbyqxmd.com/read/29600410/butyrylcholinesterase-level-as-an-independent-factor-of-erythropoiesis-stimulating-agent-resistance-in-patients-on-maintenance-hemodialysis-a-single-center-cross-sectional-study
#10
Teppei Okamoto, Shingo Hatakeyama, Yoshimi Tanaka, Kengo Imanishi, Tooru Takashima, Fumitada Saitoh, Takuya Koie, Tadashi Suzuki, Chikara Ohyama
BACKGROUND: Erythropoiesis-stimulating agent (ESA) responsiveness is related to the nutritional status of patients on hemodialysis (HD). Serum butyrylcholinesterase (BChE), an alpha-glycoprotein, may decrease in case of malnutrition. We investigated whether BChE was independently related to ESA resistance in patients on HD. METHODS: The laboratory data and ESA resistance index (ERI), defined as ESA dosage per week divided by dry weight and hemoglobin, were investigated in 215 patients on HD between July and September 2017...
March 29, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29578398/variability-of-serum-phosphorus-and-its-association-with-mortality-among-hemodialysis-patients
#11
Minxia Zhu, Linbin Dou, Mingli Zhu, Shang Liu, Yaping Zhan, Jiayue Lu, Zhaohui Ni, Jiaqi Qian, Hong Cai, Weiming Zhang
OBJECTIVE: To determine the relationship between the variability of serum phosphorus and mortality among maintenance hemodialysis (MHD) patients. MATERIALS AND METHODS: A total of 502 MHD cases were studied from the Shanghai Renal Registry Network. Serum phosphorus variability was indicated by a coefficient of variation (CV). According to the CV median of serum phosphorus, patients were divided into two groups: a high-variability group (CV ≥ 0.226 mmol/L) and a low-variability group (CV < 0...
August 2018: Clinical Nephrology
https://www.readbyqxmd.com/read/29515436/association-between-age-and-changes-in-heart-rate-variability-after-hemodialysis-in-patients-with-diabetes
#12
Sheng-Wen Niu, Jiun-Chi Huang, Szu-Chia Chen, Hugo Y-H Lin, I-Ching Kuo, Pei-Yu Wu, Yi-Wen Chiu, Jer-Ming Chang
Background: Heart rate variability (HRV) represents changes in the time between successive heart beats, and it has been used to assess the autonomic nervous system. Previous studies have reported autonomic dysfunction in diabetic patients undergoing hemodialysis (HD), however, no studies have evaluated the effects of age on changes in HRV in these patients. The aim of this study was to examine the effects of age on changes in HRV in diabetic HD patients. Methods: We enrolled 84 diabetic patients receiving maintenance HD...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29456208/morbidity-and-mortality-of-hospitalized-hip-fractures-in-chronic-hemodialysis
#13
Georgios Vlachopanos, Theodoras Kassimatis, Anastasia Kokkona, Adamantia Zerva, Eirini Stavroulaki, Charilaos Zacharogiannis, Athanasios Agrafiotis
Abnormal bone architecture contributes to high incidence of hip fractures in chronichemodialysis (HD) patients. Their clinical epidemiology is incompletely described. We conducted a retrospective cohort study to assess the implications ofhospitalization with hip fracture in HD patients compared to the nonchronic kidney disease population. Thirty-three chronic HD patients admitted with hip fracture overfiveyears were age- and sex-matched on a 1:1 ratio with controls that had hip fracture and normal renal function...
January 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29424185/predictors-of-early-failure-and-secondary-patency-in-native-arteriovenous-fistulas-for-hemodialysis
#14
Rui Abreu, Sara Rioja, Joaquin Vallespin, Xavier Vinuesa, Ruben Iglesias, Jose Ibeas
BACKGROUND: Native arteriovenous fistula (AVF) is considered the gold standard of vascular access for hemodialysis due to its longer survival, fewer complications, lower mortality and costs. Patency is important for effective dialysis treatment and this remains a challenge in nephrology. There are no well-defined prognostic factors for early and long-term AVF survival. The aim of this study was to evaluate comorbidity, analytical and ultrasound (US) variables as prognostic factors for early failure and AVF patency...
August 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29320770/long-term-survivor-characteristics-in-hemodialysis-patients-with-type-2-diabetes
#15
Susanne Triebswetter, Lena J Gutjahr-Lengsfeld, Kay-Renke Schmidt, Christiane Drechsler, Christoph Wanner, Vera Krane
BACKGROUND: Data concerning long-term mortality predictors among large, purely diabetic hemodialysis collectives are scarce. METHODS: We used data from a multicenter, prospective, randomized trial among 1,255 hemodialysis patients with type 2 diabetes mellitus (T2DM) and its observational follow-up study. The association of 10 baseline candidate variables with mortality was assessed by Cox proportional hazards regression. RESULTS: Overall, 103 participants survived the median follow-up of 11...
2018: American Journal of Nephrology
https://www.readbyqxmd.com/read/29282123/impact-of-risk-factors-on-functional-status-in-maintenance-hemodialysis-patients
#16
Jin-Bor Chen, Wen-Chin Lee, Ben-Chung Cheng, Sin-Hua Moi, Cheng-Hong Yang, Yu-Da Lin
OBJECTIVES: To survey by measuring patient's functional status which is crucial when end-stage renal disease patients begin a dialysis program. The influence of the disease on patients can be examined by the measurement of Karnofsky Performance Status (KPS) scores, together with a quality of life survey, and clinical variables. METHODS: The details for the dataset in the study were collected from patients receiving regular hemodialysis (HD) in one hospital, which were available retrospectively for 1166 patients during the 5-year study period...
December 28, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/29227261/clinical-features-of-therapy-of-anemia-and-the-significance-of-its-fluctuation-in-the-development-of-anemia-in-dialysis-patients
#17
E Lapina, M Batiushin, V Terentiev, M Gasanov, A Gasanova
The aim of our study was to examine the features of therapy of anemia, and the influence of fluctuation in dose of antianemic drugs on hemoglobin levels in dialysis patients. The study included 100 patients with chronic kidney disease stage 5D receiving hemodialysis, mean age was 53,4±15,8 years. The clinical and anamnestic data were studied and laboratory tests were performed in all patients. The correlation between hemoglobin level and fluctuations in dose of antianemic drugs for 12 months: erythropoietin (R= -0,51, p=0,004) and iron (R= -0,46, p=0,01) was determined...
November 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29223661/-is-cancer-incidence-different-between-type-2-diabetes-patients-compared-to-non-diabetics-in-hemodialysis-a-study-from-the-rein-registry
#18
Aurélie Le Guillou, Adelaide Pladys, Wahida Kihal, Muriel Siebert, Atman Haddj-Elmrabet, Charlotte Cernon, Anne Bernard, Christophe Charasse, Lise Mandart, Didier Hamel, Tugdual Tanquerel, Bernard Strullu, Christine Richer, Pascale Siohan, Théophile Sawadogo, Juliette Baleynaud, Simona Baluta, Sahar Bayat, Cécile Vigneau
BACKGROUND AND OBJECTIVES: In France, diabetes mellitus is now the second cause of end stage renal disease. In a large previous French national study, we observed that dialyzed diabetics have a significant lower risk of death by cancer. This first study was focused on cancer death but did not investigate cancer incidence. In this context, the aim of this second study was to compare the incidence of cancer in diabetic dialyzed patients compared to non-diabetic dialyzed patients in a French region...
May 2018: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29187037/modeling-a-predictive-energy-equation-specific-for-maintenance-hemodialysis
#19
Laura D Byham-Gray, J Scott Parrott, Emily N Peters, Susan Gould Fogerite, Rosa K Hand, Sean Ahrens, Andrea Fleisch Marcus, Justin J Fiutem
BACKGROUND: Hypermetabolism is theorized in patients diagnosed with chronic kidney disease who are receiving maintenance hemodialysis (MHD). We aimed to distinguish key disease-specific determinants of resting energy expenditure to create a predictive energy equation that more precisely establishes energy needs with the intent of preventing protein-energy wasting. MATERIALS AND METHODS: For this 3-year multisite cross-sectional study (N = 116), eligible participants were diagnosed with chronic kidney disease and were receiving MHD for at least 3 months...
March 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29166378/blood-pressure-variability-is-independent-of-systolic-pressure-in-adolescent-and-young-adult-patients-undergoing-hemodialysis
#20
Jingjing Da, Zulong Zhang, Yan Shen, Qian Li, Ying Hu, Yan Zha
BackgroundPre-dialysis blood pressure variability (BPV) in adolescent and young-adult maintenance hemodialysis (MHD) patients remains unknown. This study aimed to show the degree of 44-h BPV and to explore its related risk factors in adolescent and young-adult MHD patients.MethodsOne hundred and fifty-three hemodialysis patients aged from 14 to 29 were selected from 11 medical facilities in Guizhou, China. Variability independent of the mean BP (VIM) obtained by 44-h ambulatory BP monitoring was used to calculate BPV...
March 2018: Pediatric Research
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