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https://www.readbyqxmd.com/read/29701391/diagnostic-challenges-in-chronic-constrictive-pericarditis
#1
Ana Braga, Afonso Oliveira, Kevin Domingues, Maria João Andrade, Miguel Abecacis, José Pedro Neves
INTRODUCTION: Chronic constrictive pericarditis (CCP) is a disease that has multiple possible causes and is associated with variable clinical findings, depending on its severity. It develops insidiously, and in many cases, particularly in developed countries, no antecedent diagnosis can be found. These cases are termed idiopathic. Tuberculosis is the leading cause of constrictive pericarditis in developing nations but represents only a small minority in developed countries. METHODS: Here the authors describe two different case reports where tuberculosis was the probable cause of CCP...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29662645/a-novel-herbal-formula-sge-induces-endoplasmic-reticulum-stress-mediated-cancer-cell-death-and-alleviates-cachexia-symptoms-induced-by-colon-26-adenocarcinoma
#2
Aeyung Kim, Minju Im, Jin Yeul Ma
Cachexia in cancer patients, characterized by marked involuntary weight loss and impaired physical function, is associated with a poor prognosis in response to conventional treatment and with an increase in cancer-related mortality. Prevention of skeletal muscle loss under cancer-induced cachexia via inhibition of pro-cachectic factors, as well as a reduction in tumor mass, has been considered reasonable pharmacological and nutritional interventions to treat cancer patients. In this study, we constructed a novel herbal formula, SGE, which contains Ginseng Radix alba, Atractylodis Rhizoma alba , and Hoelen , examined its anti-cancer and anti-cachexia efficacies...
March 27, 2018: Oncotarget
https://www.readbyqxmd.com/read/29582895/-feeling-more-self-confident-cheerful-and-safe-experiences-from-a-health-promoting-intervention-in-community-dwelling-older-adults-a-qualitative-study
#3
Å von Berens, A Koochek, M Nydahl, R A Fielding, T Gustafsson, D R Kirn, T Cederholm, M Södergren
OBJECTIVES: Studies show that regular exercise in combination with nutritional support can be effective in managing sarcopenia, which is age-related involuntary loss of skeletal muscle mass and strength. Qualitative investigations of participants' experiences from interventions in this domain are scarce. In this study, we explored older persons' experiences from an intervention designed to prevent sarcopenia, with the aim of capturing the participants' thoughts and opinions. DESIGN: A qualitative study embedded in the multicenter randomized clinical trial The Vitality and Vigor in the Elderly study, VIVE2...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29575771/the-habenula-as-a-novel-link-between-the-homeostatic-and-hedonic-pathways-in-cancer-associated-weight-loss-a-pilot-study
#4
Maria Maldonado, David L Molfese, Humsini Viswanath, Kaylah Curtis, Ashley Jones, Teresa G Hayes, Marco Marcelli, Sanjay Mediwala, Philip Baldwin, Jose M Garcia, Ramiro Salas
BACKGROUND: Little is known about the brain mechanisms underlying cancer-associated weight loss (C-WL) in humans despite this condition negatively affecting their quality of life and survival. We tested the hypothesis that patients with C-WL have abnormal connectivity in homeostatic and hedonic brain pathways together with altered brain activity during food reward. METHODS: In 12 patients with cancer and 12 healthy controls, resting-state functional connectivity (RSFC, resting brain activity observed through changes in blood flow in the brain which creates a blood oxygen level-dependent signal that can be measured using functional magnetic resonance imaging) was used to compare three brain regions hypothesized to play a role in C-WL: the hypothalamus (homeostatic), the nucleus accumbens (hedonic), and the habenula (an important regulator of reward)...
March 25, 2018: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/29529142/prospective-associations-of-poor-diet-quality-with-long-term-incidence-of-protein-energy-malnutrition-in-community-dwelling-older-adults-the-health-aging-and-body-composition-health-abc-study
#5
Linda M Hengeveld, Hanneke A H Wijnhoven, Margreet R Olthof, Ingeborg A Brouwer, Tamara B Harris, Stephen B Kritchevsky, Anne B Newman, Marjolein Visser
Background: Protein-energy malnutrition (PEM) is a major problem in older adults. Whether poor diet quality is an indicator for the long-term development of PEM is unknown. Objective: The aim was to determine whether poor diet quality is associated with the incidence of PEM in community-dwelling older adults. Design: We used data on 2234 US community-dwelling older adults aged 70-79 y of the Health, Aging, and Body Composition (Health ABC) Study...
February 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29499371/association-between-involuntary-weight-loss-with-low-muscle-mass-and-health-related-quality-of-life-in-community-dwelling-older-adults-nationwide-surveys-knhanes-2008-2011
#6
Miji Kim, Junghoon Kim, Chang Won Won
OBJECTIVES: To investigate the relationship between involuntary weight loss with low muscle mass and health-related quality of life in a large representative sample of older adults. METHODS: A nationwide cross-sectional study based on data from the Korea National Health and Nutritional Examination Survey, 2008 to 2011. Study participants included 2249 individuals aged ≥70 years. The participants reported an unintentional weight loss >3 kg in the past year...
June 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29427379/phase-correcting-non-local-means-filtering-for-diffusion-weighted-imaging-of-the-spinal-cord
#7
Sevgi Gokce Kafali, Tolga Çukur, Emine Ulku Saritas
PURPOSE: DWI suffers from low SNR when compared to anatomical MRI. To maintain reasonable SNR at relatively high spatial resolution, multiple acquisitions must be averaged. However, subject motion or involuntary physiological motion during diffusion-sensitizing gradients cause phase offsets among acquisitions. When the motion is localized to a small region, these phase offsets become particularly problematic. Complex averaging of acquisitions lead to cancellations from these phase offsets, whereas magnitude averaging results in noise amplification...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29191597/anamorelin-for-advanced-non-small-cell-lung-cancer-with-cachexia-systematic-review-and-meta-analysis
#8
Kenichi Nishie, Shuhei Yamamoto, Chie Nagata, Tomonobu Koizumi, Masayuki Hanaoka
INTRODUCTION: Cancer anorexia-cachexia syndrome (CACS) is characterized by involuntary weight loss. CACS is commonly observed in advanced non-small-cell lung cancer (NSCLC), and it leads to a poor quality of life (QOL). No effective standard treatment exists for this condition. However, anamorelin has reportedly caused improvement in patients with several cancers. MATERIALS AND METHODS: We conducted a quantitative meta-analysis to explore the efficacy of anamorelin for treating CACS in patients with NSCLC...
October 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29151831/a-low-proportion-of-malnourished-patients-receive-nutrition-treatment-results-from-nutritionday
#9
C Henriksen, I M Gjelstad, H Nilssen, R Blomhoff
NutritionDay is a yearly point-prevalence study of malnutrition in hospitals from more than 50 countries. The aim of the present study was to quantify the frequency of malnutrition and the proportion of malnourished patients receiving nutritional treatment in two university hospitals in Norway using data from nutritionDay. All units at Oslo University Hospital (OUH) and University Hospital of Northern Norway (UNN) were invited to participate in nutritionDay 2014, and 28 out of 85 eligible units agreed to take part...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/29094998/-nutritional-and-functional-state-of-patients-with-chronic-obstructive-pulmonary-disease-effects-of-oral-nutritional-supplementation-ofos-study
#10
Maria Del Pilar Benito Martínez, Jorge Estanislao La Serna Infantes, Marta Guarro Riba, Mireia Morera Inglès, Diego Marco Camere Colarossi, Marco Antonio Camere Torrealva
INTRODUCTION: Weight loss and malnutrition are associated with a worse prognosis of chronic obstructive pulmonary disease (COPD). OBJECTIVE: The main objective of the OFOS study was to assess the efficacy and tolerability of a new nutritional oral formula in adults with COPD with weight loss or malnutrition. METHODS: Prospective, single-centre, randomized, open-label and controlled trial conducted in Lima (Peru). A total of 99 outpatients of both sexes were included (control [GC]: 49; supplement [GS]: 50), aged from 18 to 80 years old, who had been diagnosed with COPD and that suffered from malnutrition or involuntary weight loss during the last months...
July 28, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29067433/urinary-incontinence-in-women-a-review
#11
REVIEW
Emily S Lukacz, Yahir Santiago-Lastra, Michael E Albo, Linda Brubaker
Importance: Urinary incontinence, the involuntary loss of urine, is a common health condition that may decrease quality of life. Ten to twenty percent of women and up to 77% of women residing in nursing homes have urinary incontinence, yet only 25% seek or receive treatment. Observations: This review summarizes the evaluation and therapeutic options for women affected by urinary incontinence. The initial assessment should focus on understanding the effect of incontinence on quality of life, the patient's goals and preferences for treatment, the results of previous treatments, and the presence of concomitant conditions, such as advanced pelvic organ prolapse, that may require referral...
October 24, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29017480/longitudinal-assessment-of-daily-activity-patterns-on-weight-change-after-involuntary-job-loss-the-adapt-study-protocol
#12
Patricia L Haynes, Graciela E Silva, George W Howe, Cynthia A Thomson, Emily A Butler, Stuart F Quan, Duane Sherrill, Molly Scanlon, Darlynn M Rojo-Wissar, Devan N Gengler, David A Glickenstein
BACKGROUND: The World Health Organization has identified obesity as one of the most visible and neglected public health problems worldwide. Meta-analytic studies suggest that insufficient sleep increases the risk of developing obesity and related serious medical conditions. Unfortunately, the nationwide average sleep duration has steadily declined over the last two decades with 25% of U.S. adults reporting insufficient sleep. Stress is also an important indirect factor in obesity, and chronic stress and laboratory-induced stress negatively impact sleep...
October 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28929907/management-of-obesity-after-spinal-cord-injury-a-systematic-review
#13
Mir Hatef Shojaei, Seyed Mohammad Alavinia, B Catharine Craven
CONTEXT: Individuals with chronic spinal cord injury (SCI) are susceptible to central and visceral obesity and it's metabolic consequences; consensus based guidelines for obesity management after SCI have not yet been stablished. OBJECTIVES: To identify and compare effective means of obesity management among SCI individuals. METHODS: This systematic review included English and non-English articles, published prior to April 2017 found in the PubMed/Medline, Embase, CINAHL Psychinfo and Cochrane databases...
November 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28891198/targeted-medical-nutrition-for-cachexia-in-chronic-obstructive-pulmonary-disease-a-randomized-controlled-trial
#14
Philip C Calder, Alessandro Laviano, Fredrik Lonnqvist, Maurizio Muscaritoli, Maria Öhlander, Annemie Schols
BACKGROUND: Cachectic patients with chronic obstructive pulmonary disease (COPD) may benefit from nutritional support. This double-blind, randomized, controlled trial evaluated the safety and efficacy of targeted medical nutrition (TMN) vs. an isocaloric comparator in pre-cachectic and cachectic patients with COPD. METHODS: Patients aged ≥50 years with moderate-to-severe COPD and involuntary weight loss or low body mass index (16-18 kg/m2 ) were randomized 1:1 to receive TMN (~230 kcal; 2 g omega-3 fatty acids; 10 μg 25-hydroxy-vitamin D3) or isocaloric comparator twice daily for 12 weeks (ClinicalTrials...
February 2018: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28855891/hypothalamic-inflammation-and-energy-balance-disruptions-spotlight-on-chemokines
#15
REVIEW
Ophélia Le Thuc, Katharina Stobbe, Céline Cansell, Jean-Louis Nahon, Nicolas Blondeau, Carole Rovère
The hypothalamus is a key brain region in the regulation of energy balance as it controls food intake and both energy storage and expenditure through integration of humoral, neural, and nutrient-related signals and cues. Many years of research have focused on the regulation of energy balance by hypothalamic neurons, but the most recent findings suggest that neurons and glial cells, such as microglia and astrocytes, in the hypothalamus actually orchestrate together several metabolic functions. Because glial cells have been described as mediators of inflammatory processes in the brain, the existence of a causal link between hypothalamic inflammation and the deregulations of feeding behavior, leading to involuntary weight loss or obesity for example, has been suggested...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28764647/relationship-between-oral-health-and-fried-s-frailty-criteria-in-community-dwelling-older-persons
#16
Benedikta Kamdem, Laurence Seematter-Bagnoud, Fabiana Botrugno, Brigitte Santos-Eggimann
BACKGROUND: Oral health and frailty might be linked through several pathways, but previous studies are scarce. This study examined the association between oral health and components of Fried's frailty phenotype. METHODS: This cross-sectional analysis was based on a sample of 992 community-dwelling persons aged 73 to 77 years observed in the 2011 follow-up of the Lausanne 65+ cohort (Lc65+) study. Data were collected through annual mailed questionnaires, interview and physical examination...
August 1, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28760658/frailty-body-composition-and-nutritional-status-in-non-institutionalised-elderly
#17
Leonel São Romão Preto, Maria do Carmo Dias Conceição, Telma Martins Figueiredo, Maria Augusta Pereira Mata, Pedro Miguel Barreira Preto, Ester Mateo Aguilar
OBJECTIVE: Frailty is a clinical syndrome characterized, among other signs, by involuntary weight loss and decreased muscle strength. The aim of this study was to analyse associations between frailty, body composition and nutritional status in non-institutionalised elderly people in the municipality of Alfândega (Braganza-Portugal). METHOD: Observational, prevalence and association study involving 220 elderly (mean 75.8±6.8 years of age; 68.8% women). Frailty was assessedt according to Fried criteria, body composition by bioelectrical impedance analysis and nutritional status using the Mini Nutritional Assessment Short-Form...
July 28, 2017: Enfermería Clínica
https://www.readbyqxmd.com/read/28759113/feasibility-and-preliminary-effects-of-resistance-training-and-nutritional-supplements-during-versus-after-radiotherapy-in-patients-with-head-and-neck-cancer-a-pilot-randomized-trial
#18
RANDOMIZED CONTROLLED TRIAL
Jon Arne Sandmael, Asta Bye, Tora Skeidsvoll Solheim, Guro Birgitte Stene, Lene Thorsen, Stein Kaasa, Jo-Åsmund Lund, Line Merethe Oldervoll
BACKGROUND: Patients with head and neck cancer (HNC) experience involuntary weight loss that has a negative impact on physical function, morbidity, and survival. The objective of the current study was to evaluate the feasibility of an exercise and nutrition intervention during radiotherapy (RT) compared with after RT, and to examine preliminary effects on skeletal muscle mass. METHODS: Patients with HNC were randomized to an exercise and nutrition intervention during RT (EN-DUR) or after RT (EN-AF)...
November 15, 2017: Cancer
https://www.readbyqxmd.com/read/28758698/patients-with-established-cancer-cachexia-lack-the-motivation-and-self-efficacy-to-undertake-regular-structured-exercise
#19
David Wasley, Nichola Gale, Sioned Roberts, Karianne Backx, Annmarie Nelson, Robert van Deursen, Anthony Byrne
OBJECTIVES: Patients with advanced cancer frequently suffer a decline in activities associated with involuntary loss of weight and muscle mass (cachexia). This can profoundly affect function and quality of life. Although exercise participation can maintain physical and psychological function in patients with cancer, uptake is low in cachectic patients who are underrepresented in exercise studies. To understand how such patients' experiences are associated with exercise participation we investigated exercise history, self-confidence and exercise motivations in patients with established cancer cachexia, and relationships between relevant variables...
July 31, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28717810/association-between-adiposity-and-disability-in-the-lc65-cohort
#20
N Danon-Hersch, S Fustinoni, P Bovet, J Spagnoli, B Santos-Eggimann
OBJECTIVES: To examine the longitudinal association between body mass index (BMI) and waist circumference (WC) with mortality and incident disability in Lc65+ cohort. DESIGN: Population-based cohort of non-institutionalized adults with up to 8.9 years of follow-up. SETTING: City of Lausanne, Switzerland. PARTICIPANTS: 1,293 individuals aged 65 to 70 at baseline (58% women). MEASUREMENTS: BMI, WC and covariates were measured at baseline in 2004-2005...
2017: Journal of Nutrition, Health & Aging
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