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Nutrition protein

Luoyi Zhu, Ao Yang, Yang Mu, Niya Zhang, Lvhui Sun, Shahid Ali Rajput, Desheng Qi
The aim of this study was to evaluate the effects of dietary non-gossypol cottonseed oil (CSO) or cottonseed meal (CSM) and their interactions on the texture properties, structure, nutritional composition, and edible safety of egg yolk. A total of 162 24-wk-old Hy-line Brown laying hens were randomly allocated into 9 diet treatments with 6 replicates of 3 hens per cage. A 3 × 3 factorial design using corn soybean meal-based diets supplemented with 0, 6, or 12% CSM and 0, 2, or 4% CSO in place of soybean meal and soybean oil, respectively, was utilized...
August 11, 2018: Poultry Science
Gavriel D Kohlberg, Ryan T Demmer, Anil K Lalwani
OBJECTIVE: We investigated the hypothesis that childhood obesity is a risk factor for sensorineural hearing loss (SNHL) independent of other metabolic risk factors. STUDY DESIGN: A complex, multistage, stratified geographic area design for collecting representative data from noninstitutionalized US population. METHODS: A total of 5,638 adolescents between age 12 and 19 from the NHANES database (2005-2010) were studied. Subjects with body mass index >= 95th percentile were classified as obese...
August 13, 2018: Otology & Neurotology
Liang Li, Lei Hu, Chunyanzhao Zhao, Sheng-Hua Zhang, Rong Wang, Yi Li, Rong-Guang Shao, Yongsu Zhen
Depending on increasing extracellular proteins utilization and altering metabolic programs, cancer cell could proliferate and survive unrestrictedly by ingesting human serum albumin (HSA) to serve as nutritional amino acids. Here, we hypothesize that the consumption of albumin by cancer cells could be utilized as an efficient approach to targeted drug delivery. Lidamycin (LDM), an antitumor antibiotic with extremely potent cytotoxicity to cultured cancer cells, consists of an apoprotein (LDP) and an active enediyne chromophore (AE)...
August 14, 2018: Bioconjugate Chemistry
Patricio López-Jaramillo, Johanna Otero, Paul Anthony Camacho, Manuel Baldeón, Marco Fornasini
Introduction: The consumption of saturated fats is considered a risk factor for cardiovascular diseases. Objective: Review published papers on the role of macro-nutrient intake in cardiovascular risk. Results: Recent reports from the PURE study and several previous meta-analyses, show that the consumption of total saturated and unsaturated fat is not associated with risk of acute myocardial infarction or mortality due to cardiovascular disease...
June 30, 2018: Colombia Médica: CM
Beatriz Pelegrina-Cortés, Laura M Bermejo, Bricia López-Plaza, Samara Palma-Milla, Natalia García-Vázquez, Carmen Gómez-Candela
Individualized parenteral nutrition is the most specialized type of nutritional support in the hospital setting. The composition and prescribing patterns for parenteral nutrition have evolved due to new emerging scientific evidence. In the last few years, there has been a tendency to increase the nitrogen and lipid content and decrease the carbohydrate content. To assess the prescribing pattern in a tertiary referral hospital in Spain, the nutritional composition of individualized parenteral nutrition was evaluated retrospectively from January to December of 2016...
August 13, 2018: Nutrients
A E Sanders, S R Shaikh, G D Slade
The objective of this study was to assess whether dietary intake of long-chain omega-3 polyunsaturated fatty acids (PUFAs) is associated with lower prevalence of headache in the U.S. POPULATION: This cross-sectional study used data for a nationally representative sample of 12,317 men and women aged ≥ 20 years participating in the National Health and Nutrition Examination Surveys of 1999-2004. Interviewers recorded self-report of severe headache or migraine in the past three months...
August 2018: Prostaglandins, Leukotrienes, and Essential Fatty Acids
Gabriela Añorve-Valdez, Amado David Quezada-Sánchez, Fabiola Mejía-Rodríguez, Armando García-Guerra, Lynnette Marie Neufeld
BACKGROUND: Nutritional supplements are an important source of complementary food for young children, since they may either complement or substitute nutrients obtained from other food sources. Assessing how the introduction of different types of supplements modifies the consumption of other food sources may help in designing supplementation programs that aim to improve the nutrition of vulnerable populations. The objetive is to quantify dietary energy and nutrient intake among children aged 6-12 months who received one of three nutritional supplements...
August 13, 2018: Nutrition Journal
Marije N van Doorn-van Atten, Lisette C P G M de Groot, Jeanne H M de Vries, Annemien Haveman-Nies
Optimal diet quality and physical activity levels are essential for healthy ageing. This study evaluated the effects of a multi-component telemonitoring intervention on behavioural determinants of diet quality and physical activity in older adults, and assessed the mediating role of these determinants and two behaviour change techniques in the intervention's effects. A non-randomised controlled design was used including 214 participants (average age 80 years) who were allocated to the intervention or control group based on municipality...
August 10, 2018: Nutrients
Amy Kolb, Friedhelm Hildebrandt, Christian Lawrence
Zebrafish (Danio rerio) have proven their efficiency as an animal model for genetics and development, but their nutrition and housing requirements continue to elude researchers. Diet and housing density were predicted to affect weight change and reproductive success in 120 days postfertilization (dpf) zebrafish, and growth performance of their progeny. Fish were fed one of four diets, each utilizing a different primary protein source (fish meal [Zeigler™], algae, or insect), while being housed 3.3 or 6.6 fish/L for 3 weeks...
August 13, 2018: Zebrafish
Tiffany M N Otero, Cecilia Canales, D Dante Yeh, Ali Elsayes, Donna M Belcher, Sadeq A Quraishi
BACKGROUND: Hospital-acquired pressure injuries (HAPIs) typically develop following critical illness due to immobility and suboptimal perfusion. Vitamin D helps to maintain epithelial cell integrity, particularly at barrier sites such as skin. It is unclear whether vitamin D status is a modifiable risk factor for HAPIs in critically ill patients. Our goal was to investigate the relationship between admission 25-hydroxyvitamin D (25OHD) levels with the development of HAPIs in surgical intensive care unit (ICU) patients...
August 13, 2018: Nutrition in Clinical Practice
Julia B Greer, Phil Greer, Bimaljit S Sandhu, Samer Alkaade, C Mel Wilcox, Michelle A Anderson, Stuart Sherman, Timothy B Gardner, Michele D Lewis, Nalini M Guda, Thiruvengadam Muniraj, Darwin Conwell, Gregory A Cote, Christopher E Forsmark, Peter A Banks, Gong Tang, Kim Stello, Andres Gelrud, Randall E Brand, Adam Slivka, David C Whitcomb, Dhiraj Yadav
BACKGROUND: Chronic pancreatitis (CP) patients frequently experience malabsorption and maldigestion, leading to micronutrient and macronutrient deficiencies. Comorbid diabetes and lifestyle habits, such as alcohol consumption, may impact nutrition status. METHODS: We compared micronutrient antioxidant, bone metabolism, serum protein, and inflammatory marker levels in 301 CP patients and 266 controls with no known pancreatic disease. We analyzed serum prealbumin and retinol binding protein; vitamins A, D, E, and B12; osteocalcin; tumor necrosis factor-α; and C-reactive protein (CRP)...
August 13, 2018: Nutrition in Clinical Practice
Cheng Xiong, Dan Luo, Aihua Lin, Chunli Zhang, Libo Shan, Ping He, Bo Li, Qiaomei Zhang, Bin Hua, Zilv Yuan, Hanxia Li, Junhong Zhang, Changxian Yang, Yongen Lu, Zhibiao Ye, Taotao Wang
Carotenoids play important roles in many biological processes, such as light harvesting, photoprotection and visual attraction in plants. However, the regulation of carotenoid biosynthesis is still not fully understood. Here, we demonstrate that SlBBX20, a B-box (BBX) zinc-finger transcription factor, is a positive regulator of carotenoid accumulation in tomato (Solanum lycopersicum). Overexpression of SlBBX20 leads to dark green fruits and leaves and higher levels of carotenoids relative to the wild-type. Interactions between SlBBX20 and DE-ETIOLATED 1 (SlDET1) lead to the ubiquitination and 26S proteasome-mediated degradation of SlBBX20...
August 13, 2018: New Phytologist
Vincenzo De Iuliis, Antonio Marino, Marika Caruso, Sabrina Capodifoglio, Vincenzo Flati, Anna Marynuk, Valeria Marricareda, Sebastiano Ursi, Paola Lanuti, Claudio Talora, Pio Conti, Stefano Martinotti, Elena Toniato
Autophagy is a not well-understood conserved mechanism activated during nutritional deprivation in order to maintain cellular homeostasis. In the present study, we investigated the correlations between autophagy, apoptosis and the MAPK pathways in melanoma cell lines. We demonstrated that during starvation the EGF receptor mediated signaling activates many proteins involved in the MAPK pathway. Our data also suggest a previously unidentified link between the EGFR and Beclin-1 in melanoma cell line. We demonstrated that, following starvation, EGFR binds and tyrosine-phosphorylates Beclin-1, suggesting that it may play a key inhibitory role in the early stage of starvation, possibly through the Beclin-1 sequestration...
July 13, 2018: Oncotarget
Shanshan Li, Ling Li, Qingkun Zeng, Jianxin Liu, Yongxin Yang, Daxi Ren
The aim of this study was to characterize whey proteins and their potential activities among buffalo breeds. In this work, a tandem mass tag (TMT) proteomic approach was used to identify the differences in the proteomes of milk whey proteins in Murrah, Nili-Ravi and Mediterranean buffaloes. A total of 580 proteins were identified in buffalo milk whey, and the subunits of the 62 differentially expressed proteins are shown in clustering analysis. Whey proteins with relatively higher levels in Mediterranean buffalo milk than in Murrah and Nili-Ravi buffalo milk included polymeric immunoglobulin receptor, α1-antiproteinase, heat shock cognate 71-kDa protein, and Acyl-CoA-binding protein...
December 15, 2018: Food Chemistry
Astrid S Doorduijn, Ondine van de Rest, Wiesje M van der Flier, Marjolein Visser, Marian A E de van der Schueren
OBJECTIVES: Protein and energy malnutrition and unintended weight loss are frequently reported in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD). Possible underlying mechanisms include increased energy expenditure, altered uptake of nutrients, a reduced nutritional intake, or a combination of these 3. We aimed at systematically reviewing the literature to examine potential differences in energy and protein intake in patients with MCI and AD compared to controls as a possible mechanism for unintended weight loss...
August 9, 2018: Journal of the American Medical Directors Association
Chao Li, Qian Ni, Yifang Pei, Yi Ren, Yufei Feng
BACKGROUND & AIMS: We performed a meta-analysis of data from recent studies to evaluate the safety and efficacy of parenteral nutrition (PN) with structured triglyceride (STG) lipid emulsions compared to medium-chain triglyceride (MCT)/long-chain triglyceride (LCT) lipid emulsions in Chinese patients. METHODS: PubMed, Embase, Cochrane Library, China National Knowledge Internet, Wanfang, and VIP were searched for randomized controlled trials comparing STGs with MCTs/LCTs published in English or Chinese between January 1987 and October 2017...
July 25, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Nazareth Torres, M Carmen Antolín, Idoia Garmendia, Nieves Goicoechea
Tempranillo grapevine is widely cultivated in Spain and other countries over the world (Portugal, USA, France, Australia, and Argentina, among others) for its wine, but leaves are scarcely used for human or animal nutrition. Since high temperatures affect quality of fruits and leaves in grapevine and the association of Tempranillo with arbuscular mycorrhizal fungi (AMF) enhances the antioxidant properties of berries and leaves, we assessed the effect of elevated air temperature and mycorrhization, separately or combined, on the nutritional properties of Tempranillo leaves at the time of fruit harvest...
August 4, 2018: Plant Physiology and Biochemistry: PPB
Liyun Yin, Bijuan Chen, Bin Xia, Xiaotao Shi, Keming Qu
Uptake and toxicity of microplastics on marine organisms have been reported elsewhere. However, there is limited knowledge regarding the ecological effects of microplastics on marine organisms. In this study, we investigated the effects of polystyrene microplastics (1 × 106 microspheres per L) on the behavior, energy reserve and nutritional composition of juvenile jacopever (Sebastes schlegelii). Compared to the controls, fish treated by microplastics showed lower sensitivity toward the added food in the tank, and increased foraging time, indicating that microplastics significantly weakened feeding activity of the fish...
August 3, 2018: Journal of Hazardous Materials
Manoj G Kulkarni, Kannan R R Rengasamy, Srinivasa C Pendota, Jiří Gruz, Lenka Plačková, Ondřej Novák, Karel Doležal, Johannes Van Staden
Bioactive compounds such as karrikinolide (KAR1 from smoke) and eckol (from the seaweed Ecklonia maxima) show promising effects on several important crop plants. These plant growth-stimulating organic biomolecules, along with crude extracts (smoke-water and Kelpak® product prepared from Ecklonia maxima), were tested on spinach plants. Eckol sprayed at 10-6 M significantly increased all the growth and biochemical parameters examined compared to control spinach plants. All tested plant growth biostimulants significantly increased total chlorophyll, carotenoids and protein content of spinach leaves...
August 8, 2018: New Biotechnology
Alexey Koval, Constant A Pieme, Emerson Ferreira Queiroz, Simone Ragusa, Kamal Ahmed, Artem Blagodatski, Jean-Luc Wolfender, Tatiana V Petrova, Vladimir L Katanaev
Triple-negative breast cancer (TNBC) and colon cancer (CC) are two stigmatic examples of poorly treatable tumors, whose progression critically depends upon hyperactivation of the Wnt signaling. Development of specific anti-Wnt inhibitors is required to develop drugs against these and other Wnt-dependent cancers. Natural products, especially plants, have been used for the treatment of various diseases from ancient times. We examined extracts from several indigenous Cameroonian herbs and tested their effects on proliferation and Wnt signaling in TNBC and CC cells...
August 8, 2018: Cancer Letters
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