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https://www.readbyqxmd.com/read/30320531/repeated-computerized-cognitive-testing-performance-shifts-and-test-retest-reliability-in-healthy-older-adults
#1
Naomi White, Larnee Flannery, Alice McClintock, Liana Machado
INTRODUCTION: Repeated cognitive assessment is frequently required to monitor changes in cognitive functioning in older adults, but studies of repeated computerized testing in this population are scarce. To provide new insight into retest effects this study examined within- and between-day performance shifts and test-retest reliability among healthy older adults for test scores from a computerized cognitive battery. METHOD: Thirty older men (65-71 years) completed the battery six times...
October 15, 2018: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/30315687/transversus-abdominis-plane-block-versus-port-site-local-anaesthetic-infiltration-in-laparoscopic-excision-of-endometriosis-a-double-blind-randomized-placebo-controlled-trial
#2
Roxana Kargar, Vasilis Minas, Atefeh Gorgin Karaji, Khadijeh Shadjoo, Roya Padmehr, Arash Mohazzab, Anahita Enzevaei, Saghar Samimi Sadeh, Koorosh Kamali, Shaheen Khazali
OBJECTIVE: To compare the efficiency of laparoscopically-guided transversus abdominis plane block (LTAP) versus port-site local anaesthetic infiltration (LAI) in reducing postoperative pain following laparoscopic excision of endometriosis. DESIGN: A prospective, double-blind randomized controlled trial. SETTING: A tertiary referral centre for endometriosis and minimally invasive gynaecological surgery. POPULATION: Women undergoing laparoscopic excision of endometriosis from December 2015 through July 2016...
October 13, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/30304665/comparison-of-postoperative-analgesia-in-patients-undergoing-ileostomy-closure-with-and-without-dual-transversus-abdominis-plane-tap-block-a-randomized-controlled-trial
#3
Abhijit Nair, Veena Enagandula Amula, Vibhavari Naik, Praveen Kumar Kodisharapu, Anne Poornachand, M S Shyam Prasad, Mohammed Salman Saifuddin, Basanth Kumar Rayani
BACKGROUND AND AIMS: Multimodal analgesia comprising opioid, paracetamol, and non-steroidal anti-inflammatory drugs is used for managing postoperative surgical pain after ileostomy closure (IC). We investigated the efficacy of unilateral dual transversus abdominis plane (TAP) block to reduce morphine consumption in the first 24 hours along with a reduction in visual analogue score for pain and in postoperative nausea/vomiting. METHODS: This was a single-center, investigator-initiated, prospective, parallel-group, placebo-controlled randomized study involving patients undergoing IC under general anesthesia...
October 4, 2018: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/30288098/plasma-ropivacaine-concentration-after-tap-block-in-a-patient-with-cardiac-and-renal-failure
#4
Takashi Ishida, Satoshi Tanaka, Akiyuki Sakamoto, Takanobu Hirabayashi, Mikito Kawamata
We report a successful ultrasound-guided transversus abdominis plane (TAP) block as an analgesic option for minor abdominal surgery in a 66-year-old patient with cardiac, respiratory, and renal dysfunction caused by primary systemic amyloidosis. Bilateral TAP blocks with 120 mg (1.8 mg/kg) of ropivacaine provided sufficient intra- and postoperative analgesia for insertion of a continuous ambulatory peritoneal dialysis catheter. However, the plasma concentration of ropivacaine reached a maximum of 2.5 µg/mL at 15 minutes after the TAP block, a concentration that was potentially neurotoxic...
2018: Local and Regional Anesthesia
https://www.readbyqxmd.com/read/30283187/quadratus-lumborum-block-versus-transversus-abdominis-plane-block-in-patients-undergoing-total-abdominal-hysterectomy-a-randomized-prospective-controlled-trial
#5
Naglaa Khalil Yousef
Background: Abdominal hysterectomy is associated with sever postoperative pain. Quadratus lumborum (QL) block is a regional analgesic technique which has an evolving role in postoperative analgesia. Aims: we aimed to compare ultrasound guided bilateral transverse abdominis plane (TAP) block versus bilateral QL block in patients undergoing total abdominal hysterectomy. Settings and Design: This is a prospective randomized controlled double blinded study...
July 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/30280303/idiopathic-ventricular-arrhythmias-arising-from-the-posterior-septum-of-tricuspid-and-mitral-annuli-comparison-of-electrocardiographic-characteristics-and-outcomes-of-catheter-ablation
#6
Eiji Sato, Tetsuo Yagi, Akihiko Ishida, Yoshiaki Mibiki, Yoshihiro Yamashina, Hirokazu Sato, Takashi Nakagawa, Kosuke Aoki, Keisuke Suzuki, Izutsu Takuma, Tomoyuki Yambe
PURPOSE: Ventricular arrhythmia (VA) arising from the tricuspid annulus in the posterior septum (PS) (TAPS-VA) has similar electrocardiographic characteristics as VA arising from the mitral annulus in the PS (MAPS-VA) because the two locations are adjacent. We examined the electrocardiographic characteristics that differentiate MAPS-VA from TAPS-VA and the efficacy of catheter ablation. METHODS: We studied 13 patients whose VAs were successfully ablated in the TAPS (n = 7) and MAPS (n = 6)...
October 2, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/30271190/effects-of-tapentadol-on-pain-motor-symptoms-and-cognitive-functions-in-parkinson-s-disease
#7
Ulderico Freo, Maurizio Furnari, Carlo Ori
Background: Pain is a common and undertreated non-motor symptom in patients with Parkinson's disease (PD). Opioids have been seldom used in PD because they could worsen cognitive and motor functions. Objective: We aimed to assess efficacy and tolerability of tapentadol in PD patients. Methods: We retrospectively reviewed 21 PD patients treated with tapentadol extended release (ER) for chronic pain. Patients were evaluated before treatment and at 3 and 6 months during treatment for pain intensity (current, 24-hour average, and minimum and worst) with a 0-10 Numerical Rating Scale and the painDETECT questionnaire; for motor symptom severity with the Unified PD Rating Scale part III and the Hoehn and Yahr scale; for cognitive functions with Mini-Mental Status Examination, Corsi's Block-Tapping test, Digit Span test, Digit-Symbol Substitution test, FAS test, Rey's Auditory Verbal Learning test, Trail-Making test A and B and the 9-Hole Peg test; for anxiety and depression with the Hospital Anxiety and Depression Scale; and for the quality of life with the Short Form-12...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/30254564/effects-of-galvanic-vestibular-stimulation-on-upper-and-lower-extremities-motor-symptoms-in-parkinson-s-disease
#8
Mahta Khoshnam, Daniela M C Häner, Eunice Kuatsjah, Xin Zhang, Carlo Menon
As a neurodegenerative movement disorder, Parkinson's disease (PD) is commonly characterized by motor symptoms such as resting tremor, rigidity, bradykinesia, and balance and postural impairments. While the main cause of PD is still not clear, it is shown that the basal ganglia loop, which has a role in adjusting a planned movement execution through fine motor control, is altered during this disease and contributes toward the manifested motor symptoms. Galvanic vestibular stimulation (GVS) is a non-invasive technique to influence the vestibular system and stimulate the motor system...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/30250819/an-evaluation-of-the-adding-magnesium-sulfate-to-ropivacaine-on-ultrasound-guided-transverse-abdominis-plane-block-after-abdominal-hysterectomy
#9
Farnad Imani, Poupak Rahimzadeh, Hamid-Reza Faiz, Alireza Abdullahzadeh-Baghaei
Background: Post-hysterectomy pain is extremely annoying and using transverse abdominis plane (TAP) block can be a useful method to manage postoperative pain, but its duration of effect is challenging. Magnesium sulfate increases, in some cases, the effects of local anesthetics on the peripheral nerve blocks. Objectives: The current study aimed at investigating the effects of adding magnesium sulfate to ropivacaine in the transverse abdominis plane block after hysterectomy...
August 2018: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/30215460/the-analgesic-efficiency-of-transversus-abdominis-plane-tap-block-after-caesarean-delivery
#10
Anna Kupiec, Jacek Zwierzchowski, Joanna Kowal-Janicka, Waldemar Goździk, Tomasz Fuchs, Michał Pomorski, Mariusz Zimmer, Andrzej Kübler
OBJECTIVES: The ultrasound-guided transversus abdominis plane (TAP) block is a supporting method of pain relief after different types of surgical and gynecological procedures. The aim of the present study was to evaluate the analgesic effects of the TAP-block in patients undergoing caesarean section. MATERIAL AND METHODS: 88 women undergoing elective caesarean section under spinal anaesthesia were prospectively randomized into two groups. In the first group, an ultrasound-guided bilateral TAP block was performed using 40 mL 0...
2018: Ginekologia Polska
https://www.readbyqxmd.com/read/30215098/genetics-of-antigen-processing-and-presentation
#11
REVIEW
Adrian Kelly, John Trowsdale
Immune response to disease requires coordinated expression of an army of molecules. The highly polymorphic MHC class I and class II molecules are key to control of specificity of antigen presentation. Processing of the antigen, to peptides or other moieties, requires other sets of molecules. For classical class I, this includes TAP peptide transporters, proteasome components and Tapasin, genes which are encoded within the MHC. Similarly, HLA-DO and -DM, which influence presentation by HLA class II molecules, are encoded in the MHC region...
September 13, 2018: Immunogenetics
https://www.readbyqxmd.com/read/30198931/transversus-abdominal-plane-block-in-children-efficacy-and-safety-a-randomized-clinical-study-and-pharmacokinetic-profile
#12
Chrystelle Sola, Cecilia Menacé, Sophie Bringuier, Anne-Charlotte Saour, Olivier Raux, Olivier Mathieu, Xavier Capdevila, Christophe Dadure
BACKGROUND: The transversus abdominis plane (TAP) block has become a common regional anesthesia technique for pain management in a wide variety of abdominal procedures. Evidence to support any particular local anesthetic regimen as well as pharmacokinetic and systemic toxicity risks of TAP block remain insufficiently studied in children. The aim of this study was to compare the analgesic effects and investigate pharmacokinetic profile of levobupivacaine after ultrasound-guided TAP block using a low volume/high concentration (LVHC) or a high volume/low concentration (HVLC) solution in children...
September 5, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/30197532/paravertebral-blocks-and-enhanced-recovery-after-surgery-protocols-in-breast-reconstructive-surgery-patient-selection-and-perspectives
#13
REVIEW
Rajiv P Parikh, Terence M Myckatyn
The management of postoperative pain is of critical importance for women undergoing breast reconstruction after surgical treatment for breast cancer. Mitigating postoperative pain can improve health-related quality of life, reduce health care resource utilization and costs, and minimize perioperative opiate use. Multimodal analgesia pain management strategies with nonopioid analgesics have improved the value of surgical care in patients undergoing various operations but have only recently been reported in reconstructive breast surgery...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/30190339/molecular-neuroprotection-induced-by-zinc-dependent-expression-of-hepatitis-c-derived-protein-ns5a-targeting-kv2-1-potassium-channels
#14
Jason A Justice, Daniel T Manjooran, Chung-Yang Yeh, Karen A Hartnett-Scott, Anthony J Schulien, Gabrielle J Kosobucki, Shalom Mammen, Michael J Palladino, Elias Aizenman
We present the design of an innovative molecular neuroprotective strategy, and provide proof-of-concept for its implementation, relying on the injury-mediated activation of an ectopic gene construct. As oxidative injury leads to the intracellular liberation of zinc, we hypothesize that tapping onto the zinc-activated metal regulatory element ( MRE ) transcription factor 1 (MTF-1) system to drive expression of the Kv2.1-targeted hepatitis C protein NS5A, will provide neuroprotection by preventing cell death-enabling cellular potassium loss in rat cortical neurons in vitro...
September 6, 2018: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/30179891/the-evolution-of-iliac-bone-graft-donor-site-analgesia-in-cleft-patients-transversus-abdominis-plane-block-is-safe-and-efficacious
#15
Imran R A Punekar, Peter F Koltz, Daryl I Smith, Nobuyuki H Tran, Ashwani K Chibber, Hani Sbitany, John A Girotto, Clinton Morrison
BACKGROUND: The transversus abdominis plane (TAP) block has been increasingly used as a means of abdominal wall analgesia. This study aims to determine if TAP block analgesia provides a benefit in cleft patients undergoing alveolar bone grafting with iliac crest cancellous bone graft. METHODS: Two groups of 20 consecutive patients undergoing alveolar bone grafting with iliac crest cancellous bone with either TAP block or indwelling catheter pain pump were examined in a retrospective fashion...
October 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/30173291/laparoscopic-assisted-transversus-abdominis-plane-block-as-an-effective-analgesic-in-total-extraperitoneal-inguinal-hernia-repair-a-double-blind-randomized-controlled-trial
#16
A Mughal, A Khan, J Rehman, H Naseem, R Waldron, M Duggan, W Khan, K Barry, I Z Khan
PURPOSE: Laparoscopic inguinal hernia repair has facilitated early mobilization. Management of post-operative pain is paramount in these day case procedures. The aim of this study was to compare laparoscopic-assisted transversus abdominis plane (TAP) block with periportal local anaesthetic infiltration in managing post-operative pain. METHODS: A double-blind, randomized controlled trial was conducted with patients undergoing elective laparoscopic inguinal hernia repair (January 2016-October 2017)...
October 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/30170687/efficacy-of-transversus-abdominis-plane-tap-block-in-pain-management-after-laparoscopic-sleeve-gastrectomy-lsg-a-double-blind-randomized-controlled-trial
#17
Alan A Saber, Young C Lee, Arjun Chandrasekaran, Namik Olivia, Armand Asarian, Samir Al-Ayoubi, Robert DiGregorio
BACKGROUND: The aim of this randomized controlled trial was to assess the effectiveness of transversus abdominis plane (TAP) block in post-operative pain management in patients undergoing laparoscopic sleeve gastrectomy (LSG). METHODS: Ninety consecutive patients undergoing LSG were randomly assigned to three groups: placebo, TAP block with 0.25% bupivacaine (40mL total), and TAP block with 0.25% bupivacaine + 1/100,000 epinephrine (40mL total). Pain and nausea/vomiting scores were evaluated at varying times until discharge...
August 1, 2018: American Journal of Surgery
https://www.readbyqxmd.com/read/30167381/social-functioning-impairments-in-schizotypy-when-social-cognition-and-neurocognition-are-not-impaired
#18
Maral Aghvinian, Mark J Sergi
The present study examined the social, cognitive, and emotional functioning of persons with schizotypy. Over 2000 undergraduate students were screened for schizotypy with the Schizotypal Personality Questionnaire - Brief over two consecutive semesters. Ninety-two persons with high schizotypy and 22 persons with low schizotypy completed measures of social functioning (Social Adjustment Scale, Social Functioning Scale, MOS Social Support Survey), working memory (Paced Auditory Serial Addition Test, Digit Span, Letter-Number Sequencing, Corsi Block Tapping Test) and empathy (Interpersonal Reactivity Index, Empathy Quotient)...
December 2018: Schizophrenia Research. Cognition
https://www.readbyqxmd.com/read/30131739/tapping-the-full-potential-jumping-performance-of-volleyball-athletes-in-game-like-situations
#19
Marie-Therese Fleddermann, Karen Zentgraf
Background: One key issue in elite interactive team sports is the simultaneous execution of motor actions (e.g., dribbling a ball) and perceptual-cognitive tasks (e.g., visually scanning the environment for action choices). In volleyball, one typical situation is to prepare and execute maximal block jumps after multiple-options decision-making and concurrent visual tracking of the ongoing game dynamics to find an optimal blocking location. Based on resource-related dual- and multi-tasking theories simultaneous execution of visual-cognitive and motor tasks may interfere with each other...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/30131685/continuous-environmental-changes-may-enhance-topographic-memory-skills-evidence-from-l-aquila-earthquake-exposed-survivors
#20
Laura Piccardi, Massimiliano Palmiero, Alessia Bocchi, Anna Maria Giannini, Maddalena Boccia, Francesca Baralla, Pierluigi Cordellieri, Simonetta D'Amico
Exposure to environmental contextual changes, such as those occurring after an earthquake, requires individuals to learn novel routes around their environment, landmarks and spatial layout. In this study, we aimed to uncover whether contextual changes that occurred after the 2009 L'Aquila earthquake affected topographic memory in exposed survivors. We hypothesized that individuals exposed to environmental changes-individuals living in L'Aquila before, during and after the earthquake (hereafter called exposed participants, EPs)-improved their topographic memory skills compared with non-exposed participants (NEPs) who moved to L'Aquila after the earthquake, as only EPs had to modify their previous cognitive map of L'Aquila...
2018: Frontiers in Human Neuroscience
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