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https://www.readbyqxmd.com/read/30484332/impact-of-combination-of-local-anaesthetic-wounds-infiltration-and-ultrasound-transversus-abdominal-plan-us-tap-block-in-patients-undergoing-robot-assisted-radical-prostatectomy-perioperative-results-of-a-double-blind-randomized-controlled-trial
#1
Giovanni Cacciamani, Nicola Menestrina, Marco Pirozzi, Alessandro Tafuri, Paolo Corsi, Davide De Marchi, Davide Inverardi, Tania Processali, Niccolò Trabacchin, Mario De Michele, Marco Sebben, Maria Angela Cerruto, Vincenzo de Marco, Filippo Migliorini, Antonio Benito Porcaro, Walter Artibani
OBJECTIVE To determinate benefits of the combination of local anaesthetic wounds infiltration and Ultrasound Transversus Abdominal Plane (US-TAP) block with ropivacaine on postoperative pain, early recovery and hospital stay in patients undergoing robot assisted radical prostatectomy (RARP). METHODS The study is double-blinded randomized controlled trial. Our hypothesis was that the combination of wound infiltration and US-TAP block with Ropivacaine would decrease immediate post-operative pain and opioids use...
November 28, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/30475260/dexmedetomidine-as-an-adjuvant-to-local-anesthetics-in-transversus-abdominis-plane-block-a-systematic-review-and-meta-analysis
#2
Qianchuang Sun, Shuyan Liu, Huiying Wu, He Ma, Wei Liu, Meidan Fang, Kexiang Liu, Zhenxiang Pan
OBJECTIVES: The objective of this meta-analysis was to evaluate the analgesic effects of dexmedetomidine (DEX) in transversus abdominis plane (TAP) blocks for abdominal surgery. METHODS: Electronic databases, including PubMed, EMBASE, Chinese National Knowledge Infrastructure (CNKI), Wan Fang, and the Cochrane Library , were conducted to collect the randomized controlled trials (RCTs) from inception to March 2018. RCTs investigating the impact of adding DEX to local anesthetics for TAP blocks were included in this analysis...
November 20, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/30429737/evaluation-of-thoracolumbar-interfascial-plane-block-for-postoperative-analgesia-after-herniated-lumbar-disc-surgery-a-randomized-clinical-trial
#3
Mona Ahmed Ammar, Mohamed Taeimah
Background: Thoracolumbar interfascial plane (TLIP) block involves injection of local anesthetics between multifidus and longissimus muscles at the 3rd lumbar vertebral level assuming that it can block the dorsal rami of thoracolumbar nerves. Objective: The objective of this study was to evaluate the analgesic effects gained after performing TLIP block (analogous to the transversus abdominis plane [TAP] block, but intended for the back) in patients undergoing lumbar discectomy...
October 2018: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/30429282/tapping-into-the-treasures-of-tubulin-using-novel-protein-production-methods
#4
REVIEW
Nuo Yu, Niels Galjart
Microtubules are cytoskeletal elements with important cellular functions, whose dynamic behaviour and properties are in part regulated by microtubule-associated proteins (MAPs). The building block of microtubules is tubulin, a heterodimer of α- and β-tubulin subunits. Longitudinal interactions between tubulin dimers facilitate a head-to-tail arrangement of dimers into protofilaments, while lateral interactions allow the formation of a hollow microtubule tube that mostly contains 13 protofilaments. Highly homologous α- and β-tubulin isotypes exist, which are encoded by multi-gene families...
November 14, 2018: Essays in Biochemistry
https://www.readbyqxmd.com/read/30425560/effects-of-transversus-abdominis-plane-blocks-after-hysterectomy-a-meta-analysis-of-randomized-controlled-trials
#5
Hong Zhou, Xuefeng Ma, Jinghua Pan, Hanlin Shuai, Shanshan Liu, Xin Luo, Ruiman Li
Background: Transversus abdominis plane (TAP) block can provide effective analgesia for abdominal surgery. However, many randomized controlled trials (RCTs) have shown controversial results in hysterectomy. We conducted a meta-analysis of RCTs to investigate the effectiveness of TAP block after hysterectomy. Methods: Studies were gathered from PubMed, MEDLINE, EMBASE, Cochrane Library, Web of Science, and ClinicalTrials.gov databases up to March 2018. RCTs involving TAP blocks in women undergoing hysterectomy were selected...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/30417718/cognitive-motor-interference-in-persons-with-multiple-sclerosis-during-five-upper-limb-motor-tasks-with-different-complexity
#6
Joke Raats, Ilse Lamers, Ilse Baert, Barbara Willekens, Renee Veldkamp, Peter Feys
BACKGROUND: Cognitive-motor interference in multiple sclerosis has been well examined during walking, but not during upper limb (UL) performance. OBJECTIVES: To examine the dual-task cost (DTC) in persons with multiple sclerosis (pwMS) and healthy controls (HC) in various type and complexity of UL motor tasks. METHOD: In total, 30 pwMS without major UL impairment and 30 HC performed five different UL tasks, in single condition and combined with the phonemic word list generation task...
November 12, 2018: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/30416635/the-analgesic-efficacy-of-transverse-abdominis-plane-block-versus-epidural-block-after-caesarean-delivery-which-one-is-effective-tap-block-epidural-block
#7
Ebru Canakci, Ahmet Gultekin, Zubeyir Cebeci, Bulent Hanedan, Anil Kilinc
Introduction and Objective: TAP block has gained popularity to provide postoperative analgesia after abdominal surgery but its advantage over epidural analgesia is disputed. For lower abdominal surgeries, epidural analgesia has been the gold standard and time-tested technique for providing postoperative analgesia, but contraindications for the same would warrant need for other equally good analgesic techniques. The objective of this study is to compare the analgesic efficacy of both the techniques...
2018: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/30390161/transversus-abdominis-block-utilizing-liposomal-bupivacaine-as-a-non-opioid-analgesic-for-postoperative-pain-management
#8
Thomas C Robertson, Kathryn Hall, Susan Bear, Kyle J Thompson, Timothy Kuwada, Keith S Gersin
INTRODUCTION: The use of non-narcotic modalities for postoperative analgesia may decrease exposure to opioids, thereby limiting their deleterious effects. The objective of this study was to determine the effectiveness of a liposomal bupivacaine transverse abdominis plane (TAP) block prior to laparoscopic sleeve gastrectomy (LSG) and laparoscopic gastric bypass (LRYGB). The primary outcome was total postoperative morphine equivalents. METHODS: A single-surgeon, IRB-approved retrospective chart review was performed on consecutive patients who underwent LRYGB or LSG from 2010 to 2016...
November 2, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/30388647/diverse-and-abundant-antibiotics-and-antibiotic-resistance-genes-in-an-urban-water-system
#9
Haiwei Huang, Siyu Zeng, Xin Dong, Dan Li, Ye Zhang, Miao He, Pengfei Du
The widespread use of antibiotics has resulted in pollution associated with antibiotics and antibiotic resistance genes (ARGs) in urban water systems, threatening the public health and the ecological security. In this study, the patterns of the diversity and abundance of the antibiotics and ARGs in a typical city (Kunming, China) were analyzed by monitoring their presence in the tap water, the land block sewage discharge units, the sewage pipes, the influent of WWTP, the effluent of WWTP, and the urban river channel...
October 26, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/30373789/flashpack-fast-and-simple-preparation-of-ultra-high-performance-capillary-columns-for-lc-ms
#10
Sergey I Kovalchuk, Ole N Jensen, Adelina Rogowska-Wrzesinska
Capillary ultra-high-pressure liquid chromatography (cUHPLC) is essential for in-depth characterization of complex biomolecule mixtures by LC-MS. We developed a simple and fast method called FlashPack for custom packing of capillary columns of 50-100 cm length with sub-2-mm sorbent particles. FlashPack uses high sorbent concentrations of 500-1000 mg/ml for packing at relatively low pressure of 100 bar. Column blocking by sorbent aggregation is avoided during the packing by gentle mechanical tapping of the capillary proximal end by a slowly rotating magnet bar...
October 29, 2018: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/30365254/-application-of-transcutaneous-electrical-acupoint-stimulation-combined-with-transversus-abdominis-plane-block-to-enhanced-recovery-after-surgery-in-patients-undergoing-laparoscopic-colorectal-cancer-resection-a-randomized-controlled-clinical-trial
#11
Wei Huang, Ting-Yu Yu, Wen-Fei Long, Jian-Bin Xiao
OBJECTIVE: To explore the effect of transcutaneous electrical acupoint stimulation (TEAS) combined with transversus abdominis plane (TAP) block in the enhanced recovery after surgery (ERAS) in patients undergoing laparoscopic colorectal cancer resection (LCCR). METHODS: A total of 101 patients undergoing LCCR were randomly divided into three groups: control ( n =34), TAP ( n =35) and TEAS+TAP ( n =32). Conventional perioperative anesthesia management of the 3 groups was performed according to the ERAS guidelines...
October 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/30364775/ultrasound-guided-transversus-abdominis-plane-tap-block-utilization-in-multimodal-pain-management-after-open-gynecologic-surgery
#12
Heidi Chang, B J Rimel, Andrew J Li, Ilana Cass, Beth Y Karlan, Christine Walsh
Transversus abdominis plane (TAP) block is a peripheral nerve block directed at the nerves in the anterior abdominal wall. We sought to determine whether TAP block reduces post-operative narcotic use or length of stay after open gynecologic surgery. Among 98 women who underwent an open hysterectomy between July 2016 - July 2017 by a gynecologic oncologist, 73 (74.5%) received a TAP block. The majority of patients who received a TAP block had a vertical incision (86.3%) while the majority of patients who did not receive TAP block had a transverse incision (64%)...
November 2018: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/30345190/the-efficacy-of-transversus-abdominis-plane-block-for-abdominal-hysterectomy-post-operative-analgesia
#13
Christina Dai, Kai Zhang, Jeffrey Huang
Introduction/background Abdominal hysterectomy is an open surgical procedure associated with considerable post-operative pain. Narcotics are often required during patient recovery but can result in adverse side effects. Transversus abdominis plane block (TAP block) is a regional anesthetic technique that is found to be an effective post-operative analgesia for many types of abdominal surgeries, including abdominal hysterectomies. However recent literature shows contradicting results regarding TAP block's analgesic effect on recovery from abdominal hysterectomies...
August 10, 2018: Curēus
https://www.readbyqxmd.com/read/30344666/transversus-abdominis-plane-block-reduces-remifentanil-and-propofol-consumption-evaluated-by-closed-loop-titration-guided-by-bispectral-index
#14
Jiahai Ma, Xue-Yan Wang, Qiao-Xia Sun, Jon Zhou, Tao Li, Mei-Ru Jiang, Gang-Gang Liu, Hong Liu
The present prospective, randomized, double-blind study aimed to determine the impact of transversus abdominis plane (TAP) block on propofol and remifentanil consumption, when administered by closed-loop titration guided by processed electroencephalography, i.e., bispectral index (BIS) values. Following institutional review board approval, 60 patients were scheduled for laparoscopic colectomy under general anesthesia. Patients were randomly assigned to receive bilateral TAP block with 20 ml 0.375% ropivacaine (TAP group) or 20 ml 0...
November 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/30342470/case-report-life-threatening-coronary-artery-spasm-under-transversus-abdominis-plane-block-in-combination-with-general-anesthesia
#15
Wenping Peng, Shun Huang, Shuzhen Zhou, Ning Yang, Mingzhang Zuo
BACKGROUND: Many cases of coronary artery spasm (CAS) during general plus epidural anesthesia have been reported. But transversus abdominis plane(TAP) block in combination with general anesthesia has not been reported to be a cause of CAS, let alone a life-threatening CAS. CASE PRESENTATION: In this case report, we present a case of a patient with CAS accompanied by ventricular fibrillation under general anesthesia with TAP block. CONCLUSION: Coronary artery spasm, even life-threatening CAS, may occur during TAP block in combination with general anesthesia...
October 20, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/30320531/repeated-computerized-cognitive-testing-performance-shifts-and-test-retest-reliability-in-healthy-older-adults
#16
Naomi White, Larnee Flannery, Alice McClintock, Liana Machado
INTRODUCTION: Repeated cognitive assessment is frequently required to monitor changes in cognitive functioning in older adults, but studies of repeated computerized testing in this population are scarce. To provide new insight into retest effects this study examined within- and between-day performance shifts and test-retest reliability among healthy older adults for test scores from a computerized cognitive battery. METHOD: Thirty older men (65-71 years) completed the battery six times...
October 15, 2018: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/30315687/transversus-abdominis-plane-block-versus-port-site-local-anaesthetic-infiltration-in-laparoscopic-excision-of-endometriosis-a-double-blind-randomized-placebo-controlled-trial
#17
Roxana Kargar, Vasilis Minas, Atefeh Gorgin Karaji, Khadijeh Shadjoo, Roya Padmehr, Arash Mohazzab, Anahita Enzevaei, Saghar Samimi Sadeh, Koorosh Kamali, Shaheen Khazali
OBJECTIVE: To compare the efficiency of laparoscopically-guided transversus abdominis plane block (LTAP) versus port-site local anaesthetic infiltration (LAI) in reducing postoperative pain following laparoscopic excision of endometriosis. DESIGN: A prospective, double-blind randomized controlled trial. SETTING: A tertiary referral centre for endometriosis and minimally invasive gynaecological surgery. POPULATION: Women undergoing laparoscopic excision of endometriosis from December 2015 through July 2016...
October 13, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/30304665/comparison-of-postoperative-analgesia-in-patients-undergoing-ileostomy-closure-with-and-without-dual-transversus-abdominis-plane-tap-block-a-randomized-controlled-trial
#18
Abhijit Nair, Veena Enagandula Amula, Vibhavari Naik, Praveen Kumar Kodisharapu, Anne Poornachand, M S Shyam Prasad, Mohammed Salman Saifuddin, Basanth Kumar Rayani
BACKGROUND AND AIMS: Multimodal analgesia comprising opioid, paracetamol, and non-steroidal anti-inflammatory drugs is used for managing postoperative surgical pain after ileostomy closure (IC). We investigated the efficacy of unilateral dual transversus abdominis plane (TAP) block to reduce morphine consumption in the first 24 hours along with a reduction in visual analogue score for pain and in postoperative nausea/vomiting. METHODS: This was a single-center, investigator-initiated, prospective, parallel-group, placebo-controlled randomized study involving patients undergoing IC under general anesthesia...
October 4, 2018: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/30288098/plasma-ropivacaine-concentration-after-tap-block-in-a-patient-with-cardiac-and-renal-failure
#19
Takashi Ishida, Satoshi Tanaka, Akiyuki Sakamoto, Takanobu Hirabayashi, Mikito Kawamata
We report a successful ultrasound-guided transversus abdominis plane (TAP) block as an analgesic option for minor abdominal surgery in a 66-year-old patient with cardiac, respiratory, and renal dysfunction caused by primary systemic amyloidosis. Bilateral TAP blocks with 120 mg (1.8 mg/kg) of ropivacaine provided sufficient intra- and postoperative analgesia for insertion of a continuous ambulatory peritoneal dialysis catheter. However, the plasma concentration of ropivacaine reached a maximum of 2.5 µg/mL at 15 minutes after the TAP block, a concentration that was potentially neurotoxic...
2018: Local and Regional Anesthesia
https://www.readbyqxmd.com/read/30283187/quadratus-lumborum-block-versus-transversus-abdominis-plane-block-in-patients-undergoing-total-abdominal-hysterectomy-a-randomized-prospective-controlled-trial
#20
Naglaa Khalil Yousef
Background: Abdominal hysterectomy is associated with sever postoperative pain. Quadratus lumborum (QL) block is a regional analgesic technique which has an evolving role in postoperative analgesia. Aims: we aimed to compare ultrasound guided bilateral transverse abdominis plane (TAP) block versus bilateral QL block in patients undergoing total abdominal hysterectomy. Settings and Design: This is a prospective randomized controlled double blinded study...
July 2018: Anesthesia, Essays and Researches
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