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https://www.readbyqxmd.com/read/30235860/clinical-significance-of-phase-angle-in-non-dialysis-ckd-stage-5-and-peritoneal-dialysis-patients
#1
Byoung-Geun Han, Jun Young Lee, Jae-Seok Kim, Jae-Won Yang
BACKGROUND: Fluid overload and protein-energy wasting (PEW) are common in patients with end-stage renal disease (ESRD) and lead to a poor prognosis. We aimed to evaluate the volume and nutritional status of ESRD patients and to determine the clinical significance of phase angle (PhA). METHODS: This study was a cross-sectional comparison of bioimpedance spectroscopy (BIS) findings in patients with non-dialysis chronic kidney disease (CKD) stage 5 (CKD5-ND, N = 80) and age/sex-matched peritoneal dialysis patients (PD, N = 80)...
September 19, 2018: Nutrients
https://www.readbyqxmd.com/read/30180208/executive-function-in-end-stage-renal-disease-acute-effects-of-hemodialysis-and-associations-with-clinical-factors
#2
María Del Mar Sánchez-Fernández, Gustavo A Reyes Del Paso, José Manuel Gil-Cunquero, María José Fernández-Serrano
OBJECTIVE: There is evidence of cognitive impairment in patients with end-stage renal disease in hemodialysis (ESRD-HD). However, few studies have exhaustively analyzed executive functions (EFs) in this population, especially considering the influence of a wide range of clinical variables. This study analyzes performance in different EF components in ESRD-HD patients compared to a group of healthy controls (HCs), in addition to the acute effects of HD and the associations of cognitive performance with clinical variables...
2018: PloS One
https://www.readbyqxmd.com/read/30148723/protein-carbamylation-in-end-stage-renal-disease-is-there-a-mortality-effect
#3
Sahir Kalim
PURPOSE OF REVIEW: Protein carbamylation is a posttranslational protein modification caused, in part, by exposure to urea's dissociation product cyanate. Additional modulators of protein carbamylation include circulating free amino acid levels, inflammation, diet, smoking, and environmental pollution exposures. Carbamylation reactions can modify protein charge, structure, and function, leading to adverse molecular and cellular responses. These changes have been linked to several pathologic biochemical pathways relevant to patients with end stage renal disease (ESRD) such as accelerated atherosclerosis and dysfunctional erythropoiesis, among others...
November 2018: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/30089153/serum-leptin-level-is-associated-with-phase-angle-in-ckd5-patients-not-undergoing-dialysis
#4
Jun Young Lee, Jae-Seok Kim, Jae-Won Yang, Seung Ok Choi, Joon Hyung Sohn, Byoung-Geun Han
OBJECTIVE: Malnutrition is very complex in patients with end-stage renal disease (ESRD) and is associated with poor prognosis. This is because hemodynamic changes, hormonal changes, persistent inflammatory reactions, and fluid overloads are more complicated as uremia is worsening. Bio-impedance spectroscopy (BIS) is a useful method to estimate fluid balance (Overhydration/ extracellular water, OH/ECW) and nutritional status (Phase angle, PhA). We aimed to evaluate the volume and nutritional status by BIS and to investigate the relationship between the appetite regulating hormones and the parameters of BIS in patients with stage 5 chronic kidney disease not undergoing dialysis (CKD5-ND)...
2018: PloS One
https://www.readbyqxmd.com/read/30060084/vitamin-d-deficiency-and-treatment-versus-risk-of-infection-in-end-stage-renal-disease-patients-under-dialysis-a-systematic-review-and-meta-analysis
#5
Guobin Su, Zhuangzhu Liu, Xindong Qin, Xu Hong, Xusheng Liu, Zehuai Wen, Bengt Lindholm, Juan-Jesus Carrero, David W Johnson, Nele Brusselaers, Cecilia Stålsby Lundborg
Background: Infections are common and can be fatal in patients undergoing long-term dialysis. Recent studies have shown conflicting evidence associating infection with vitamin D status or use of vitamin D and have not been systematically reviewed in this population. Methods: We searched PubMed, Web of Science, Cochrane Library, Embase and three Chinese databases from inception until December 2017 for interventional [non-randomized or randomized controlled trials (RCTs)], cohort and case-control studies on levels of serum 25-hydroxyvitamin D [25(OH)D] or use of vitamin D [supplemental nutritional vitamin D or vitamin D receptor activator (VDRA)] and infection (any infection, infection-required hospitalization or infection-related death or composite) in long-term dialysis patients...
July 27, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/30006785/ghrelin-and-acyl-ghrelin-levels-are-associated-with-inflammatory-and-nutritional-markers-and-with-cardiac-and-vascular-dysfunction-parameters-in-hemodialysis-patients
#6
Crina Claudia Rusu, Simona Racasan, Diana Moldovan, Alina Potra, Dacian Tirinescu, Cristian Budurea, Remus Orasan, Ioan Mihai Patiu, Cosmina Bondor, Dan Vladutiu, Dan Delean, Alexandra Danu, Ina Maria Kacso
PURPOSE: Exogenous ghrelin is associated with cardiovascular protection in experimental and human studies. Nevertheless ESRD patients have increased ghrelin levels and severe cardiovascular comorbidities. This study aims to elucidate the metabolic factors influencing endogenous ghrelin/acyl ghrelin levels and to analyze the relation between endogenous ghrelin/acyl ghrelin levels and cardiac and vascular function markers in hemodialysis patients. METHODS: The cross-sectional study was conducted in hemodialysis patients (n = 88); 50 of them were men, mean age 61...
July 13, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29989454/environmental-impact-on-the-onset-of-hypertension-induced-end-stage-renal-disease
#7
Kavitha Anbarasu, Vinod Kumar Verma, Syed Sultan Beevi, Velagala Satti Reddy
This study intends to assess the impact of environmental factors on the onset of hypertension-induced end-stage renal disease (ESRD) and to compare the level of oxidative stress with nonhypertensive diabetic ESRD. ESRD patients were evaluated along with healthy controls through questionnaire for demographic, nutritional and lifestyle variables. Oxidants were measured along with antioxidants. Multiple linear regression (MLR) models were applied to analyze association of studied variables with oxidants and antioxidants...
October 2018: International Journal of Environmental Health Research
https://www.readbyqxmd.com/read/29972290/nutritional-assessment-of-patients-with-end-stage-renal-disease-using-the-mna-scale
#8
Łukasz Rogowski, Mariusz Kusztal, Tomasz Gołębiowski, Katarzyna Bulińska, Agnieszka Zembroń-Łacny, Joanna Wyka, Marian Klinger, Marek Woźniewski, Wioletta Dziubek
BACKGROUND: Patient malnutrition is a significant problem in the process of rehabilitation and treatment. One of the tools that can reveal the risk of malnutrition is a series of standardized nutritional questionnaires. OBJECTIVES: The aim of the study was to assess the nutritional status of patients with end-stage renal disease (ESRD) by means of the minimal nutritional assessment (MNA) scale. MATERIAL AND METHODS: The study group included respondents suffering from ESRD who were patients of the Dialysis Center at the Clinic of Nephrology and Transplantation Medicine at the University Clinical Hospital in Wrocław...
July 4, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29952961/a-case-report-of-successful-pregnancy-and-delivery-after-peritoneal-dialysis-in-a-patient-misdiagnosed-with-primary-infertility
#9
Chi-Young Choi, Nam-Jun Cho, Samel Park, Hyo Wook Gil, Yun-Sook Kim, Eun Young Lee
RATIONALE: Currently, 15% of women in fertility age are infertile and the frequency is increasing. Among the various causes of infertility, end-stage renal disease (ESRD) has been shown to decrease the frequency of pregnancies compared with normal females. However, dialysis of patients with ESRD increases the likelihood of pregnancy.Herein, we report successful pregnancy and delivery after peritoneal dialysis in a patient who was misdiagnosed as primary infertility. PATIENT CONCERNS: A 37-year-old female who was unaware of her ESRD was misdiagnosed with primary infertility...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29926516/serum-albumin-inflammation-and-nutrition-in-end-stage-renal-disease-c-reactive-protein-is-needed-for-optimal-assessment
#10
EDITORIAL
Hideyuki Mukai, Hilda Villafuerte, Abdul Rashid Qureshi, Bengt Lindholm, Peter Stenvinkel
Low serum albumin (S-Alb) is a frequent feature of end-stage renal disease (ESRD) that independently predicts mortality. Serum albumin has mainly been considered a biomarker of visceral protein and immunocompetence status, fundamental to nutritional assessment. However, low S-albumin level is associated with persistent systemic inflammation and many bodies of evidence show that S-Alb has a limited role as a marker of nutritional status. We reported that a low S-Alb concentration was an independent risk factor for poor outcome in ESRD only in the presence of systemic inflammation...
September 2018: Seminars in Dialysis
https://www.readbyqxmd.com/read/29909606/dietary-protein-and-nutritional-supplements-in-conventional-hemodialysis
#11
Alice Sabatino, Giovanni Piotti, Carmela Cosola, Ilaria Gandolfini, Jeroen P Kooman, Enrico Fiaccadori
Protein energy wasting (PEW) is a condition commonly occurring among patients with ESRD on hemodialysis. PEW is characterized by depletion of protein and energy stores and is caused by multiple factors related to chronic kidney disease, acute and chronic comorbidities and by renal replacement therapy itself. Anorexia is central in the pathogenesis of PEW; it is frequently observed in these patients whose protein and energy intakes are typically lower than guidelines recommendations. If untreated, PEW invariably leads to major complications, and may activate a vicious circle with further worsening of nutritional status...
June 17, 2018: Seminars in Dialysis
https://www.readbyqxmd.com/read/29866494/noninvasive-evaluation-of-muscle-mass-by-ultrasonography-of-quadriceps-femoris-muscle-in-end-stage-renal-disease-patients-on-hemodialysis
#12
Alice Sabatino, Giuseppe Regolisti, Marco Delsante, Tommaso Di Motta, Chiara Cantarelli, Sarah Pioli, Giulia Grassi, Valentina Batini, Mariacristina Gregorini, Enrico Fiaccadori
BACKGROUND & AIMS: Protein-Energy Wasting (PEW) is a pathological condition of renal patients with advanced Chronic Kidney Disease characterized by a progressive reduction of energy and protein assets. Nutritional status assessment, especially for what concerns muscle mass, is essential for both the identification of patients at risk for the development of PEW, as well as monitoring the effects of nutritional interventions. Ultrasound methods are easily applicable at the bedside for quantitative assessment of skeletal muscle...
May 19, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29808451/an-update-on-calciphylaxis
#13
REVIEW
José Alberto García-Lozano, Jorge Ocampo-Candiani, Sylvia Aide Martínez-Cabriales, Verónica Garza-Rodríguez
Calciphylaxis, also known as calcific uremic arteriolopathy and uremic small artery disease with medial wall calcification and intimal hyperplasia, is a multifactorial cutaneous vascular disease characterized by chronic, painful, non-healing wounds that occur frequently in patients with chronic kidney disease, predominantly in those with end-stage renal disease. The pathogenesis remains unclear, and the development of calciphylaxis lesions depends on medial calcification, intimal fibrosis of arterioles and thrombotic occlusion...
August 2018: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/29807979/impact-of-preoperative-abdominal-visceral-adipose-tissue-area-and-nutritional-status-on-renal-function-after-donor-nephrectomy-in-japanese-living-donors-for-renal-transplantation
#14
Shunta Hori, Makito Miyake, Yosuke Morizawa, Yasushi Nakai, Kenta Onishi, Kota Iida, Daisuke Gotoh, Satoshi Anai, Kazumasa Torimoto, Katsuya Aoki, Tatsuo Yoneda, Nobumichi Tanaka, Katsunori Yoshida, Kiyohide Fujimoto
BACKGROUND Living kidney donors face the risk of renal dysfunction, resulting in end-stage renal disease, cardiovascular disease, or cerebrovascular disease, after donor nephrectomy. Reducing this risk is important to increasing survival of living donors. In this study, we investigated the effect of preoperative distribution of abdominal adipose tissue and nutritional status on postoperative renal function in living donors. MATERIAL AND METHODS Seventy-five living donors were enrolled in this retrospective study...
May 29, 2018: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/29805542/increased-prevalence-of-peripheral-arterial-disease-in-patients-with-obese-sarcopenia-undergoing-hemodialysis
#15
Shun-Li Tian, Kai Zhang, Peng-Cheng Xu
Background peripheral arterial disease (PAD) is a common complication in patients undergoing dialysis, which reduces the quality of life and increases the risk of mortality. Recent literature has documented an association between increased visceral fat (VF) content and a proatherogenic factors in end-stage renal disease. The present study investigated the prevalence of PAD in patients undergoing hemodialysis. PAD was determined as an ankle-brachial index <0.9. Additionally, VF content was determined using multiple frequency bioelectrical impendence analysis...
June 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29775238/comparison-of-creatinine-index-and-geriatric-nutritional-risk-index-for-nutritional-evaluation-of-patients-with-hemodialysis
#16
Wonsun Hwang, Mi Sook Cho, Ji Eun Oh, Ji Hyun Lee, Jong Cheol Jeong, Gyu-Tae Shin, Heungsoo Kim, Inwhee Park
INTRODUCTION: Malnutrition is prevalent in hemodialysis (HD) patients, and the risk of mortality is strongly correlated with malnutrition. Current methods of nutritional evaluation are mostly subjective, time-consuming, and cumbersome. Creatinine index (CI) and geriatric nutritional risk index (GNRI) are very simple and objective methods to assess the nutritional status of HD patients. The present study compares the performance of CI and GNRI as nutritional risk assessment tools. METHODS: Eighty-eight patients with end-stage renal disease on HD were recruited from a single tertiary center...
May 18, 2018: Hemodialysis International
https://www.readbyqxmd.com/read/29737013/incremental-dialysis-for-preserving-residual-kidney-function-does-one-size-fit-all-when-initiating-dialysis
#17
Anna T Mathew, Yoshitsugu Obi, Connie M Rhee, Jason A Chou, Kamyar Kalantar-Zadeh
While many patients have substantial residual kidney function (RKF) when initiating hemodialysis (HD), most patients with end stage renal disease in the United States are initiated on 3-times per week conventional HD regimen, with little regard to RKF or patient preference. RKF is associated with many benefits including survival, volume control, solute clearance, and reduced inflammation. Several strategies have been recommended to preserve RKF after HD initiation, including an incremental approach to HD initiation...
July 2018: Seminars in Dialysis
https://www.readbyqxmd.com/read/29707907/secondary-hyperparathyroidism-and-protein-energy-wasting-in-end-stage-renal-disease
#18
REVIEW
Hirotaka Komaba, Masafumi Fukagawa
Protein-energy wasting (PEW), a syndrome involving adverse changes in nutrition and body composition, is a serious problem associated with morbidity and mortality in patients with end-stage renal disease (ESRD). The pathogenesis of PEW is multifactorial, and the underlying mechanisms are not fully understood. However, recent translational work has provided compelling evidence for a causal role of parathyroid hormone (PTH) in the pathogenesis of adipose tissue browning and increased energy expenditure, a critical component of PEW in ESRD...
June 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29682387/surgical-management-of-encapsulating-peritoneal-sclerosis-a-case-report-in-kidney-transplant-patient
#19
R Shahbazov, M Talanian, J L Alejo, F Azari, A Agarwal, K L Brayman
Introduction: Encapsulating peritoneal sclerosis (EPS) is a clinical syndrome of progressive fibrotic change in response to prolonged, repetitive, and typically severe insult to the peritoneal mesothelium, often occurring in the setting of peritoneal dialysis (PD). Clear guidelines for successful management remain elusive. We describe the successful surgical management of EPS in a 28-year-old male s/p deceased donor kidney transplant for end-stage renal disease (ESRD) secondary to focal segmental glomerulosclerosis (FSGS)...
2018: Case Reports in Surgery
https://www.readbyqxmd.com/read/29657203/the-development-of-malnutrition-is-not-dependent-on-its-traditional-contributing-factors-in-patients-on-maintenance-hemodialysis-in-developing-countries
#20
Syed Rizwan Ali Bokhari, Mirza Ameer Faizan Ali, Syed Arsalan Khalid, Bushra Iftikhar, Hafiz Ijaz Ahmad, Ahlam Safdar Hussain, Usman Yaqoob
Malnutrition in dialysis population is associated with significant morbidity and mortality. Nutritional assessment is a neglected area in hemodialysis (HD) patients in developing countries. The aim of the study was to find out whether any traditional parameters have statistically significant correlation with malnutrition. All 58 end-stage renal disease patients on maintenance HD in our dialysis unit were enrolled in this cross-sectional study. The nutritional status was assessed by a predesigned questionnaire including subjective global assessment (SGA)...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
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