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N Atanelov, N Arutinashvili, G Burjanadze, G Kuprava, N Koshoridze
A method for isolation of polyphenol extract with significant amounts of flavonoid compounds (GOF) from precocious Georgian Citrus sinensis peels (Citrus sinensis (L.) Osbeck ,,Seike Navel", form N26) was established by multistage process based on producing water-associated fraction (WAF). Recent study describes the impact of GOF on altered cellular metabolism patterns of cardiac muscle cells and changes in blood induced by psycho-emotional stress. Markedly, GOF-treated animals show positive changes in certain antioxidant enzymes (SOD, catalase) activity and normalization of lipid peroxidation, whereas the concentration of Ca2+ and nitric oxide are approximated to the control value...
October 2018: Georgian Medical News
N Zakharenko, N Kovalenko, I Manoliak
The aim of the research is the assessment of the features of the course of endometriosis in women in perimenopause. The exanimated group of patients consisted of 106 women with endometriosis and climacteric syndrome and 64 women with endometriosis without climacteric syndrome. The comparison group consisted of 70 women without endometriosis and symptoms of climacteric syndrome. The age of the examined women was from 39 to 55 years. We analyzed the leading complaints, the menstrual function and the severity of the pain manifestations in the examined patients...
October 2018: Georgian Medical News
Steven Maxwell, Maryam Shahmanesh, Mitzy Gafos
BACKGROUND: 'Chemsex' is the use of drugs before or during planned sexual events to facilitate, enhance, prolong and sustain the experience. Drugs associated with chemsex are methamphetamine, GHB/GBL, mephedrone, cocaine and ketamine. This review syntheses published research on the antecedents, behaviours and consequences associated with chemsex behaviours among men who have sex with men (MSM). METHODS: Papers from high income countries which were published between January 2000 and September 2018 reporting the use of chemsex drugs before or during sex were identified through Medline, Web of Science, CINAHL and Central...
December 1, 2018: International Journal on Drug Policy
Bianca Senf, Jens Fettel, Christina Demmerle, Paula Maiwurm
OBJECTIVE: Clinical experience reveals a gap between recommended psychosocial care and actual support for psycho-oncology. Physicians' are essential for managing psychosocial distress and for the successful implementation of psycho-oncology. The aim was to explore physician's attitudes towards psycho-oncology, their self-perceived barriers towards referral to psycho-oncology, and their personal psychosocial competencies in a maximum-care hospital. METHOD: Semi-structured interviews informed the development of a questionnaire administered to a monocentric sample of 120 physicians at the University Hospital Frankfurt...
December 4, 2018: Psycho-oncology
Nicolas S Marjanovic, Christelle Teiten, Nicola Pallamin, Erwan L'Her
OBJECTIVE: To assess how stressful conditions in endotracheal intubation could induct emotional excitation in a population of acute care physicians. MATERIALS AND METHODS: Two situations were randomly tested: one in standard and easy intubation conditions the other under difficult conditions presumed to induce stress (monitoring alarms, manikin lying on the floor, difficult intubation). Emotional excitation was assessed using several physiological (cardiac patterns, electrodermal activity and eye-tracking) and psycho-cognitive patterns...
December 4, 2018: Annals of Intensive Care
Stefano Bambi, Andrea Guazzini, Michela Piredda, Alberto Lucchini, Maria Grazia De Marinis, Laura Rasero
BACKGROUND: Lateral violence and bullying affect nurses' professional and health status. Worldwide prevalence ranges from 1 to 87%. AIM: To investigate prevalence and risk factors of lateral violence and bullying among Italian nurse peers in different work settings, inside and outside hospitals. METHODS: Web-survey using the 17-item 'Negative Interactions Among Nurses Questionnaire'. E-mails were sent to 5009 nurses in 3 Tuscan public healthcare institutions...
December 1, 2018: Journal of Nursing Management
Omorogieva Ojo, Xiao-Hua Wang, Osarhumwese Osaretin Ojo, Jude Ibe
Background : People who abuse substances are at increased risk of metabolic syndrome and diabetes resulting partly from increased cell damage and due to the effects of opioids on glucose homeostasis. Therefore, people with diabetes who abuse substances may carry greater health risks than the general population resulting from their effect on glucose metabolism. These substances may be in the form of cannabis, hallucinogens, opioids, and stimulants. Therefore, the aim of this review was to evaluate the effects of substance abuse on blood glucose parameters in patients with diabetes...
November 29, 2018: International Journal of Environmental Research and Public Health
Dong Hwee Son, Khanh V Doan, Dong Joo Yang, Ji Su Sun, Seul Ki Kim, Namju Kang, Jung Yun Kang, Ji-Hye Paik, Ronald A DePinho, Yun-Hee Choi, Dong Min Shin, Ki Woo Kim
PURPOSE: While leptin has been associated with various psycho-physiological functions, the molecular network in leptin-mediated mood regulation remains elusive. METHODS: Anxiolytic behaviors and tyrosine hydroxylase (TH) levels were examined after leptin administration. Functional roles of STAT3 and FoxO1 in regulation of TH expression were investigated using in vivo and in vitro systems. A series of animal behavioral tests using dopaminergic neuron-specific FoxO1 KO (FoxO1 KODAT ) were performed and investigated the roles of FoxO1 in regulation of mood behaviors...
November 27, 2018: Metabolism: Clinical and Experimental
V A Badtieva, V I Pavlov, M N Khokhlova, A V Pachina
BACKGROUND: Physical overload results in the development of pathological changes in the organs and systems and thereby causes their dysfunction. This leads to disadaptation, vegetative imbalance, and disturbances in the cardiovascular, nervous, endocrine and other systems. Taken together, these changes give rise to a syndrome of overtraining. In this context, the pathogenetically sound method of therapy appears to be the most suitable for the management of this condition based on the physiotherapeutic non-invasive interventions for the correction of physiological characteristics and the psycho-emotional status of the patients...
2018: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
Arndt Büssing, Daniela Rodrigues Recchia, Loren L Toussaint
Background: In missions, soldiers are confronted with difficult situations which may impair their physical and mental health. As the resulting problems are commonly regarded as stigmata, soldiers may obviate talking about their experiences and try to oppress them. It was aim of this study to clarify whether soldiers do perceive needs to reflect back on life, to seek release from "open aspects" of their life, and to talk with others about fears and worries, to forgive others or to be forgiven. Further we intended to clarify whether these needs were related to stress perception, post-traumatic stress disorders (PTSD) symptoms and reduced life satisfaction on the one hand, and religious trust as a resource to cope on the other hand...
2018: Frontiers in Psychiatry
Stefanie Stanzer, Elisabeth Andritsch, Silke Zloklikovits, Verena Ladinek, Clemens Farkas, Thomas Augustin, Barbara Obermayer-Pietsch, Hellmut Samonigg, Thomas Bauernhofer
OBJECTIVE: The aim of this study was to determine a potential benefit of the specific psycho-educational intervention "Learning to Live with Cancer" (LTLWC) for patients with operated non-metastatic breast cancer, with respect to psychological variables and endocrine and immune parameters. METHODS: Fifty-two postmenopausal women with operated stage I - III breast cancer were randomized to either a breast cancer intervention group (BCIG, n=30) who immediately began participating in the LTLWC intervention program or to a breast cancer control group (BCCG, n=22)...
November 27, 2018: Psychosomatic Medicine
Youngmee Kim, Hannah-Rose Mitchell, Amanda Ting
BACKGROUND: Cancer affects both men and women, yet systematic understanding of the role of gender in caregiving and dyadic caregiver-patient interactions is lacking. Thus, it may be useful to review how gender theories apply to cancer caregiving, and to evaluate the adequacy of current cancer caregiving studies to the gender theories. METHODS: Several databases, including MEDLINE (Ovid), PsychINFO, PubMed, and CINAHL, were used for searching articles published in English between 2000 and 2016...
November 28, 2018: Psycho-oncology
Penelope Hopwood, Nick Hopwood
No abstract text is available yet for this article.
November 29, 2018: Psycho-oncology
Ida Elisabeth Højskov, Philips Moons, Ingrid Egerod, Peter Skov Olsen, Lau Caspar Thygesen, Niels Viggo Hansen, Søren La Cour, Krisitna Hindhede Bech, Britt Borregaard, Christian Gluud, Per Winkel, Jane Lindschou, Selina Kikkenborg Berg
OBJECTIVES: Rehabilitation of patients following coronary artery bypass grafting (CABG) has been widely studied; however, research into early rehabilitation after CABG is sparse. The aim of this trial was to assess the impact of early rehabilitation, compared with usual care in patients following CABG. DESIGN: Randomized controlled trial. PATIENTS: A total of 326 patients treated with CABG. METHODS: Patients treated with CABG were randomized 1:1 to 4 weeks of comprehensive early rehabilitation or usual care...
November 28, 2018: Journal of Rehabilitation Medicine
Alina Danet Danet, Manuela López Doblas, Joan Carles March Cerdà, María Ángeles Prieto Rodríguez
OBJECTIVE: To evaluate a peer-training intervention for women with breast cancer, from a gender perspective: to discover the results of the intervention and examine in-depth the personal experiences of patients and health professionals participating in the training activity. METHOD: Mixed method multicentre design completed in 2017 in Andalusia (Spain), with a pre and post evaluation questionnaire with 102 patients, measuring life style, limitations, use of health services, communication with professionals and self-management; and content analysis of semi-structured interviews and focus groups with 21 patient-trainers and 5 health professionals, looking at experiences, needs and suggestions for improvement...
November 24, 2018: Gaceta Sanitaria
Antonio Aiello, Christian Nardella
OBJECTIVES: The organizational well-being construct has become a theme with broad scientific and law debate, pertaining prevention and protection measures concerning work-related stress, both for assessment and intervention on psychosocial risks. This paper focuses on a case study identified in a specific organizational context of a upper middle school. METHODS: Starting from a research-intervention perspective, this paper was primarily based on the use of the "Psychosocial Risk Assessment" (Va...
June 2018: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
Marian Andrei Stanciu, Caroline Morris, Matt Makin, Eila Watson, Jenna Bulger, Richard Evans, Julia Hiscock, Zoë Hoare, Rhiannon Tudor Edwards, Richard D Neal, Seow Tien Yeo, Clare Wilkinson
OBJECTIVE: The present parallel randomised control trial evaluated the feasibility of a nurse-led psycho-educational intervention aimed at improving the self-management of prostate cancer survivors. METHODS: We identified 305 eligible patients from a district general hospital, diagnosed 9-48 months previously, who completed radical treatment, or were monitored clinically (ineligible for treatment). Ninety-five patients were recruited by blinded selection and randomised to Intervention (N = 48) and Control (N = 47) groups...
November 26, 2018: European Journal of Cancer Care
Irja Haapala, Simon Biggs, Susan Kurrle
Social aspects of dementia are becoming increasingly important as part of a wider shift in emphasis from cure to care. This is partly because approaches based on finding a cure have proved far more difficult and complex than originally imagined (WHO, 2016). New evidence on the effectiveness of public health measures, that while incidence is growing as the proportion of older people in society increases its prevalence amongst older adults is actually falling, has also lead to increased interest in social dimensions of prevention, lifestyle change, and practical intervention in community settings (Prince et al...
November 2018: International Psychogeriatrics
Muhammad Farhan, Darakshan Jabeen Haleem
Psychostimulants substances, some of which are abused by humans, are generally believed to produce sensitization effects when they are repeatedly administered to animals. Apomorphine, a non-narcotic derivative of morphine, having agonistic property for dopamine in order to produce psycho stimulant-like effects. Meanwhile, chronic administration leads to behavioral sensitization. Therefore, present study destine to produce desensitization in animals by the repeated administration of tryptophan (100 mg/kg), thereafter treated with apomorphine (1...
November 2018: Pakistan Journal of Pharmaceutical Sciences
Britt Stuge
BACKGROUND: Pregnancy-related low back pain (LBP) and pelvic girdle pain (PGP) have been associated with an alteration in the strategy for lumbopelvic stabilization. Different core stabilization approaches exist, the evidence is however controversial. METHODS: This paper discusses how to improve the evidence of exercises for women suffering from LBP and PGP during and after pregnancy. Exercises should be understood in a context, where the bio-psycho-social perspective directs the prescription of exercises, targeting both psychological and physical factors...
November 17, 2018: Brazilian Journal of Physical Therapy
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