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Ajay Kumar Jha
No abstract text is available yet for this article.
January 2019: Critical Care Medicine
Alice R Bird, David J Bird, Matthew W McMillan
OBJECTIVES: To determine the endotracheal tube cuff pressure produced with two inflation techniques, in two brands of endotracheal tube in cats. To determine the inspiratory pressure which produces an audible leak when the intracuff pressure is 30 cmH2 O. STUDY DESIGN: Prospective, clinical, randomized study. ANIMALS: A total of 40 client-owned healthy adult cats. METHODS: Following induction of anaesthesia, endotracheal intubation was performed with a Parker Flex-Tip PFLP (Parker; n = 20) or Flexicare VentiSeal (Flexicare; n = 20) endotracheal tube...
October 13, 2018: Veterinary Anaesthesia and Analgesia
Sarosh P Batlivala, Bryan H Goldstein
No abstract text is available yet for this article.
December 7, 2018: JACC. Cardiovascular Interventions
Takao Iemoto, Tsuyoshi Sanuki, Takayuki Ose, Tomoo Yoshie, Katsuhide Tanaka, Ayaka Sasaki, Shohei Abe, Tetsuyuki Abe, Mika Miki, Ryoko Futai, Yuta Inoue
BACKGROUND Adenomatous polyposis coli is an autosomal dominant hereditary disorder. Duodenal adenocarcinoma and adenoma, which are extracolonic lesions, not only affect the prognosis of patients but also cause acute pancreatitis. CASE REPORT We present the case of a 73-year-old male. He had undergone proctocolectomy for familial adenomatous polyposis and distal gastrectomy (Billroth II reconstruction with Braun anastomosis) for gastric ulcer; he presented with acute pancreatitis caused by ampullary duodenum adenoma...
December 15, 2018: American Journal of Case Reports
Alessandro Cianfoni, Daniela Distefano, Maurizio Isalberti, Michael Reinert, Pietro Scarone, Dominique Kuhlen, Joshua A Hirsch, Giuseppe Bonaldi
OBJECTIVES: To describe a new technique to obtain minimally invasive but efficient vertebral body (VB) reconstruction, augmentation, and stabilization in severe osteoporotic and neoplastic fractures, combining two pre-existing procedures. The implant of vertebral body stents (VBS) is followed by insertion of percutaneous, fenestrated, cement-augmented pedicular screws that act as anchors to the posterior elements for the cement/stent complex. The screws reduce the risk of stent mobilization in a non-intact VB cortical shell and bridge middle column and pedicular fractures...
December 14, 2018: Journal of Neurointerventional Surgery
Weifeng Sun, Junyuan Lv, Liren Duan, Ruoran Lin, Yugang Li, Shanqiong Li, Chen Fu, Lin Zhao, Shijie Xin
Vascular remodeling is mainly caused by excessive proliferation of vascular smooth muscle cells (VSMCs). Noncoding RNAs (ncRNAs) have emerged as important regulators in diverse pathological processes. Previous work has shown the functions and mechanisms of long noncoding RNA H19 (LncRNA H19) on VSMCs. As long noncoding RNAs (lncRNAs) are complex in their mechanisms of action, the aim of the study is to identify if there are any other molecular mechanisms of LncRNA H19 on VSMCs. In vivo studies demonstrated that cyclin D1 was overexpressed in neointima of balloon-injured artery...
December 11, 2018: Biochemical and Biophysical Research Communications
Songita A Choudhury, Feng Xie, Shelby Kutty, John Lof, Elizabeth Stolze, Thomas R Porter
BACKGROUND: Microbubbles (MB) can be compressed to nanometer-sized droplets and reactivated with diagnostic ultrasound; these reactivated MB possess unique imaging characteristics. OBJECTIVE: We hypothesized that droplets formed from compressing Definity MB may be used for infarct-enhancement imaging. METHODS: Fourteen rats underwent ligation of their left anterior descending (LAD) artery, and five pigs underwent 90 minute balloon occlusions of their mid LAD...
2018: PloS One
Ramzi El Hassan, Alex Galante, Michael Kavran, Stephen Ganocy, Ahmad O Khalifa, Adonis Hijaz
AIMS: Vaginal distention (VD) is a validated model of birth-related trauma in rats. Recently a mouse VD model was reported. Our study was originally conducted to evaluate the impact of age on VD in mice. This manuscript describes the study and reports on the lack of reproducibility of VD models in mice. METHODS: We utilized female C57BL/6 mice. A total of 190, 12-weeks old mice, were randomized into VD and sham groups. We inflated a modified Foley's balloon with 0...
December 14, 2018: Neurourology and Urodynamics
Elizabeth M Brunt, David E Kleiner, Laura A Wilson, Arun J Sanyal, Brent A Neuschwander-Tetri
Hepatocellular injury and inflammation are believed to be the primary drivers of fibrogenesis that ultimately lead to cirrhosis in patients with NASH. AIM: This study sought associations between observed improvements in fibrosis with improvement in specific histologic features, NAFLD Activity Score (NAS) ≥ 2, diagnostic category, and primary histologically based outcomes of two adult NASH treatment trials. The primary outcome for the study was fibrosis improvement from baseline to end of treatment, defined as a 1 point or more improvement in fibrosis stage...
December 14, 2018: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
Iosif Xenogiannis, Peter Tajti, M Nicholas Burke, Emmanouil S Brilakis
The standard treatment for large vessel coronary perforations is implantation of a covered stent. Antegrade attempts for crossing a right coronary artery chronic total occlusion resulted in guidewire and microcatheter exit with pericardial bleeding. A balloon was inflated proximal to the perforation site to achieve temporary hemostasis. Retrograde crossing of the chronic total occlusion was achieved through an epicardial collateral using the reverse controlled antegrade and retrograde tracking technique. Stent implantation resulted in hemostasis, likely due to creation of a subintimal flap that sealed the perforation site...
December 13, 2018: Catheterization and Cardiovascular Interventions
Kazuhiro Horii, Takahiko Shiina, Kiyotada Naitou, Hiroyuki Nakamori, Yuuki Horii, Hiroki Shimaoka, Yasutake Shimizu
BACKGROUND: Esophageal peristalsis is controlled by the brainstem via vago-vagal reflex. However, the precise regulatory mechanisms in the striated muscle portion are largely unknown. The aim of this study was to characterize peristaltic motility in the portion of the esophagus using a novel in vivo method in rats. METHODS: A balloon-tipped catheter was placed in the esophagus of a rat anesthetized with urethane. To induce esophageal peristalsis, the balloon was inflated by water injection...
December 14, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
Rachel M Kaplan, Ajay Yadlapati, Eric P Cantey, Rod S Passman, Mark Gajjar, Bradley P Knight, Ranya Sweis, Mark J Ricciardi, Duc T Pham, Andrei Churyla, S Chris Malaisrie, Charles J Davidson, James D Flaherty
BACKGROUND: Transcatheter aortic valve replacement (TAVR) is increasingly used to treat severe aortic stenosis. A frequent complication of TAVR is high grade or complete atrioventricular (AV) block requiring a permanent pacemaker (PPM). There is little data on the long-term dependency on pacing after TAVR. The objective of this study was to determine the proportion of patients receiving a PPM for high grade or complete AV block after TAVR who remain dependent on the PPM in follow-up and to determine any risk factors for, particularly the effect of post-balloon dilation (PBD), on pacemaker dependency...
December 13, 2018: Pacing and Clinical Electrophysiology: PACE
Cláudia Schweiger, Catherine K Hart, Meredith E Tabangin, Aliza P Cohen, Nicholas J Roetting, Alessandro de Alarcón
OBJECTIVE: To determine the appropriate balloon size for dilation using a previously described reproducible survival animal model of subglottic stenosis. STUDY DESIGN: Prospective animal study. METHODS: We conducted a prospective study including 16 New Zealand White rabbits. The airway of each animal was sized with an endotracheal tube (ETT), and subglottic stenosis (SGS) was endoscopically induced using Bugbee electrocautery to 75% of the circumference of the subglottis, followed by 4-hour intubation...
December 13, 2018: Laryngoscope
Mark V Sherrid, Katherine Riedy, Barry Rosenzweig, Monica Ahluwalia, Milla Arabadjian, Muhamed Saric, Sandhya Balaram, Daniel G Swistel, Harmony R Reynolds, Bette Kim
BACKGROUND: Acute left ventricular (LV) apical ballooning with normal coronary angiography occurs rarely in obstructive hypertrophic cardiomyopathy (OHCM); it may be associated with severe hemodynamic instability. METHODS, RESULTS: We searched for acute LV ballooning with apical hypokinesia/akinesia in databases of two HCM treatment programs. Diagnosis of OHCM was made by conventional criteria of LV hypertrophy in the absence of a clinical cause for hypertrophy and mitral-septal contact...
December 12, 2018: Echocardiography
Claudia Stöllberger, Lenka Gerencerova, Josef Finsterer
Takotsubo syndrome (TTS) is a transient transient left ventricular dysfunction, predominantly affecting elderly women and often preceded by emotional or physical stress. TTS may be the cause as well as the consequence of stroke. We report a 82-years old female with a history of long-standing untreated arterial hypertension who was hospitalized because of a left-sided tongue paralysis and dysarthria. Cerebral magnetic resonance imaging showed ischemic lesions in the territory of the right middle cerebral artery affecting the capsula interna and gyrus praecentralis...
December 2018: ENeurologicalSci
Nick H Kim, Marion Delcroix, Xavier Jais, Michael M Madani, Hiromi Matsubara, Eckhard Mayer, Takeshi Ogo, Victor F Tapson, Hossein-Ardeschir Ghofrani, David P Jenkins
Chronic thromboembolic pulmonary hypertension (CTEPH) is a complication of pulmonary embolism and a major cause of chronic PH leading to right heart failure and death. Lung ventilation/perfusion scintigraphy is the screening test of choice; a normal scan rules out CTEPH. In the case of an abnormal perfusion scan, a high-quality pulmonary angiogram is necessary to confirm and define the pulmonary vascular involvement and prior to making a treatment decision. PH is confirmed with right heart catheterisation, which is also necessary for treatment determination...
December 13, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
Verena Veulemans, Kerstin Piayda, Shazia Afzal, Amin Polzin, Christine Quast, Christian Jung, Ralf Westenfeld, Tobias Zeus, Malte Kelm, Katharina Hellhammer
BACKGROUND: Transcatheter aortic valve implantation (TAVI) has a substantial impact on daily cardiovascular care delivery based on issues such as cost effectiveness and economic value within a restricted health care budget. Until now, potential financial benefits of third generation valve models have not been evaluated in a real-world setting. METHODS AND RESULTS: We identified 204 eligible patients (Jan 2014-Sep 2016) who either received the balloon-expandable Edwards Sapien 3 (ES3) or the self-expandable Medtronic Evolut R (MER)...
December 4, 2018: International Journal of Cardiology
Shelby Sullivan, James Swain, George Woodman, Steven Edmundowicz, Tarek Hassanein, Vafa Shayani, John C Fang, Mark Noar, George Eid, Wayne J English, Nabil Tariq, Michael Larsen, Sreenivasa S Jonnalagadda, Dennis S Riff, Jaime Ponce, Dayna Early, Eric Volckmann, Anna R Ibele, Matthew D Spann, Kumar Krishnan, Juan Carlos Bucobo, Aurora Pryor
BACKGROUND: Obesity is a significant health problem and additional therapies are needed to improve obesity treatment. OBJECTIVE: Determine the efficacy and safety of a 6-month swallowable gas-filled intragastric balloon system for weight loss. SETTING: Fifteen academic and private practice centers in the United States. METHODS: This was a double-blind, randomized sham-controlled trial of the swallowable gas-filled intragastric balloon system plus lifestyle therapy compared with lifestyle therapy alone for weight loss at 6 months in participants aged 22 to 60 years with body mass index 30 to 40 kg/m2 , across 15 sites in the United States...
December 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Trevor M Downing, Sarah N Khan, Rodrick C Zvavanjanja, Zagum Bhatti, Anil K Pillai, Stephen T Kee
Portal venous interventions comprise a large portion of many Interventional Radiology practices today, and remain some of the more technically challenging cases in one's repertoire of procedures. The patients upon whom these procedures are performed are often critically ill, have decompensated disease, or are burdened with comorbid conditions such that they are poor surgical candidates. This leaves them with few options outside the care of Interventional Radiology. Some portal venous interventions, such as transjugular intrahepatic portosystemic shunt, have an established history of excellent clinical success with numerous technical advancements over the years helping to improve outcomes...
December 2018: Techniques in Vascular and Interventional Radiology
Tomo Ando, Said Ashraf, Pedro A Villablanca, Tesfaye A Telila, Hisato Takagi, Cindy L Grines, Luis Afonso, Alexandros Briasoulis
Infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) is a rare but life-threatening complication. Paravalvular regurgitation, compression of native leaflets, and space between transcatheter valve prosthesis and native valves could dispose TAVI recipients at increased risk of IE compared with SAVR. To assess the comparative risk of IE between TAVI and SAVR, we performed a systematic review and meta-analysis. A literature search of PUBMED and EMBASE was performed to identify randomized controlled trials that reported the event rate of IE in both TAVI and SAVR...
December 3, 2018: American Journal of Cardiology
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