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Vail Natale Júnior, Francisley Ávila Souza, Eduardo Vedovatto, Renato Sussumu Nishioka, Pier Paolo Poli, Paulo Sérgio Perri de Carvalho
The purpose of this study was to evaluate the preservation of alveolar dimensions in human fresh extraction sockets filled with a composite bovine bone graft by means of design of single-blind randomized clinical trial. Forty participants had monoradicular teeth extracted (one teeth in each participant), and after were randomly divided into 2 groups: individuals whose fresh sockets were filled with the composite heterologous bone graft (Biomaterial Group), or with blood clot (Control Group). After extraction, the fresh sockets were measured at their greatest mesiodistal (MD) and bucco-lingual/palatal (BL/P) distance...
November 2018: Brazilian Dental Journal
Bruce A Young, Hilary S Bierman
The middle ear cavities of crocodilians have complex connections with the pharyngeal lumen, including lateral and median components which both open into a single chamber located on the dorsal midline of the pharynx. This chamber and the surrounding soft-tissue is herein termed the median pharyngeal valve. In the American alligator (Alligator mississippiensis) this valve opens, for a duration of 0.3 s, approximately every 120 s; the patency of the median pharyngeal valve was not influenced by either auditory stimuli or by submersing the alligator underwater...
December 5, 2018: Journal of Morphology
Hai-Lei Kou, Wen-Zhou Diao, Tao Liu, Dan-Liang Yang, Suksun Horpibulsuk
The behavior of open-ended pipe piles is different from that of closed-ended pipe piles due to the soil plugging effect. In this study, a series of field tests were conducted to investigate the behavior of open-ended prestressed high-strength concrete (PHC) pipe piles installed into clay. Two open-ended PHC pipe piles were instrumented with Fiber Bragg Grating (FBG) sensors and jacked into clay for subsequent static loading tests. Soil plug length of the test piles was continuously measured during installation, allowing for calculation of the incremental filling ratio...
December 1, 2018: Sensors
M Biondi, E Vanzi, G De Otto, S F Carbone, V Nardone, F Banci Buonamici
Texture analysis (TA) applied to CT imaging is an intensely studied topic and many studies suggested TA potential value in imaging characterisation for diagnostic purposes in different fields. However, often authors do not consider the reproducibility and the robustness versus variations in acquisition parameters; in this work, we wanted to explore the robustness of the TA features extracted from CT images. We scanned a commercial phantom (CIRS model 062M) containing plugs with nine different tissue equivalent electron densities using two different CT scanners of the same vendor and changing tube current (100 and 200 mA without modulation) and peak voltage (80 and 140 kVp)...
December 4, 2018: Physics in Medicine and Biology
Surjendu Maity, Joydip Chaudhuri, Shirsendu Mitra, Saptak Rarotra, Dipankar Bandyopadhyay
We explore the improvements in yield and conversion of a chemical reaction inside a two-phase microfluidic reactor when subjected to an externally applied alternating current (AC) electric field. A computational fluid dynamic (CFD) framework has been developed to incorporate the descriptions of the two-phase flow, multicomponent transport and reaction, and the Maxwell's stresses generated at oil-water interface owing to the presence of the externally applied electric field. The CFD model ensures that the reactants are flown into a microchannel together with the oil and water phases before the reaction takes place at the interface and products diffuse back to the bulk phases...
December 4, 2018: Electrophoresis
A K Sai Siva Ram, K Pratap Reddy, B P Girish, Ch Supriya, P Sreenivasula Reddy
The aim of this study was to assess the reproductive toxic effects of arsenic on adult Wistar rats exposed to lead during the perinatal period. The pregnant rats were allowed ad libitum access to tap water containing 819 mg of lead (Pb) per L or without Pb from conception until weaning. Litter size, survival rate and developmental milestones of the pups delivered by Pb exposed dams were comparable to those of the control rats. Conversely, the pups exposed to Pb during the perinatal period exhibited significant delay in cliff avoidance, negative geotaxis, surface righting reflex, ascending wire mesh and testis descent...
November 1, 2018: Toxicology Research
Takashi Yamashita, Yoshihide Asano, Ryosuke Saigusa, Takashi Taniguchi, Megumi Hirabayashi, Takuya Miyagawa, Kouki Nakamura, Shunsuke Miura, Ayumi Yoshizaki, Maria Trojanowska, Shinichi Sato
Intravenous cyclophosphamide pulse, a standard treatment for systemic sclerosis (SSc)-related interstitial lung disease (ILD), elicits a disease-modifying effect on SSc vasculopathy, such as fostering microvascular de-remodeling. To investigate the molecular mechanism by which cyclophosphamide mitigates SSc vasculopathy, we employed endothelial cell-specific Fli1 knockout (Fli1 ECKO) mice that mimic the functional and structural vascular abnormalities characteristic of SSc. Biweekly cyclophosphamide injection improved vascular permeability and structural abnormalities of Fli1 ECKO mice in 2 weeks and in 3 months, respectively...
November 30, 2018: Journal of Investigative Dermatology
Huapeng Lin, Zheng Jin, Ying Zhu, Mengyuan Diao, Wei Hu
AIM: To compare the effectiveness of the anal fistula plug (AFP) with the rectal advancement flap (RAF) for complex cryptoglandular anal fistulas. METHODS: We conducted a literature search to identify relevant available articles published without language restriction from EMBASE and PubMed databases and the Cochrane Library. Studies comparing outcomes with the AFP versus RAF for complex cryptoglandular anal fistulas were eligible for inclusion. RESULTS: A total of 11 articles with 810 patients were included in this meta-analysis...
November 30, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
Tawseef Dar, Bharath Yarlagadda, Prasad Gunasekaran, Dhanunjaya Lakkireddy, Mark A Wiley
Ventricular free wall rupture (VFWR) is a rare entity and is mostly related to post myocardial infarction (MI) complications usually involving left ventricle. In traumatic chest injuries, the right ventricle (RV) is more commonly involved due to its anatomic and structural vulnerability, as in our case. Survival, although rare, has almost always been secondary to urgent surgical repair, which is the current standard of care for such cases. However, extremely tenuous hemodynamic parameters preclude urgent surgical interventions in most of these cases...
August 2018: Journal of Atrial Fibrillation
Alberto Romero-Palacios, Oliva Mera Gallardo, Patricia Jiménez Aguilar, José Javier Borrallo Torrejón, Carmen Maza Ortega, Manuel A Rodriguez-Iglesias
BACKGROUND: Aspergillus tracheobronchitis (ATB) is an uncommon type of invasive pulmonary aspergillosis in which fungal involvement is limited to the tracheobronchial tree. While the more severe forms, such as pseudomembranous and ulcerative ATB, occur almost exclusively in immunocompromised patients, the milder obstructive form may occur in patients without immune deficiency. CASE REPORT: The case of a 32 year-old man with no previous history of illness, who was evaluated for recurrent right lower lobe pneumonia, is presented...
November 29, 2018: Revista Iberoamericana de Micología
Luiza O Saad, Thomas Schwaha, Stephan Handschuh, Andreas Wanninger, José E A R Marian
Males from numerous animal taxa have evolved strategies for obstructing the female genitalia with copulatory plugs, reducing the risk of sperm competition and thus resulting in an advantage in sexual selection. Several lines of evidence suggest that sperm competition is a common feature in the complex squid mating systems, which include the evolution of alternative mating tactics (consort vs. sneaker). However, mating plugs have hitherto not been reported for the group. Investigating the female sperm-storage organ (i...
October 2018: Zoology: Analysis of Complex Systems, ZACS
Bingdi Cao, Ruilu Wang, Weijun Zhang, Hanjun Wu, Dongsheng Wang
Sludge treatment and disposal have become critical environmental issues in China. Electro-dewatering (ED) is an attractive technology for enhancing dewaterability and improving the sustainability of waste activated sludge (WAS) handling. However, electrically assisted mechanical dewatering processes consume more energy and the extracellular polymeric substance (EPS) dissolution caused by electrochemical reactions can lead to clogging of the filter cloth. Carbon-based materials (CBMs) such as activated carbon and graphite have electrical conductivity and well-developed pore structures which can adsorb the biopolymers...
October 31, 2018: Water Research
Shinya Ichimura, Masahito Fukuchi, Kento Takahara, Masato Nakaya, Keisuke Yoshida, Yoichi Mochizuki, Koji Fujii
OBJECTIVE: One burr hole surgery is a common treatment modality for initial chronic subdural hematoma and stereotactic hematoma surgery, but severe skin depression is often a postoperative complication. We report the autologous bone dust technique, which uses autogenous bone dust generated during burr hole creation to prevent cosmetic deformity. PATIENTS AND METHODS: The autologous bone dust technique was performed for 51 sides on which burr hole surgery was conducted mainly for chronic subdural hematoma and stereotactic hematoma removal...
November 26, 2018: Clinical Neurology and Neurosurgery
Mengru Mira Zhang, Don L Rempel, Michael L Gross
Fast Photochemical Oxidation of Protein (FPOP), based on a pulsed KrF laser (248nm) for free-radical generation, is a biophysical method that utilizes hydroxyl radicals to footprint proteins in solution. FPOP has been recognized for structural proteomics investigations, including epitope mapping, protein-aggregation characterization, protein-folding monitoring, and binding-affinity determination. The distinct merits of the platform are: i) the use of a scavenger to control radical lifetime and allow fast ("snapshot") footprinting of solvent-accessible residues in a protein; ii) the employment of a flow system to enable single-shot irradiation of small plugs of the targeted sample; iii) the use of methionine and catalase after radical oxidation chemistry to prevent post-oxidation with residual oxidizing species; and iv) the utilization of mature mass spectrometry-based proteomic methods to afford detailed analysis...
November 28, 2018: Free Radical Biology & Medicine
Junhui Zhang, Yuan Liu, Guixiu Shi
OBJECTIVE: The purpose of this study is to provide a further theoretical basis for the role of Suberoyllanilide hyroxamic acid (SAHA) affect on Dendritic cells (DCs). METHODS: We first downloaded the GSE74306 microarray data, which was about the effect of SAHA act on DCs, from the Gene Expression Omnibus database. Then we analyzed the differential expression genes (DEGs) between SAHA-treated DCs and SAHA-untreated DCs by limma package of R software; The Database for Annotation, Visualization and Integrated Discovery was used to analyze the Gene Ontology and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways for these DEGs...
November 27, 2018: Biochemical and Biophysical Research Communications
Chun-Yu Lin, I-Hao Su, Sung-Yu Chu, Po-Jen Ko
Despite recent advances in surgical techniques and endovascular devices, the management of ruptured type B aortic dissection remains challenging. Herein, we describe a patient with a history of chronic type B aortic dissection who presented to the emergency department with a massive left hemothorax and profound shock. Computed tomography demonstrated a thoracic dissecting aneurysm with false-lumen rupture. He underwent emergent thoracic endovascular aortic repair and carotid-carotid crossover bypass in a hybrid operating room...
November 27, 2018: Annals of Vascular Surgery
Sung-Whan Kim, Hyun Aae Ryu, Yong Seung Lee, In Sil Jeong, Soonhag Kim
Physical microenvironment plays an important role in determining cellular reprogramming. In this study, we first generated directly reprogrammed human dermal fibroblasts (HDFs) into endothelial cells (ECs) mediated by environmental transition-guided cellular reprogramming (e/Entr) using ultrasound and characterized e/Entr. Ultrasound stimulus was introduced to ECs culture media and HDFs and induced into ECs-like cells. We performed microarray, RT-PCR, protein analysis, matrigel plug assay and e/Entr were transplanted into ischemic hindlimb mice model...
November 27, 2018: Journal of Molecular and Cellular Cardiology
F Galeotti, M Pisco, A Cusano
Self-assembly offers a unique resource for the preparation of discrete structures at the nano- and microscale, which are either not accessible by other fabrication techniques or require highly expensive and technologically demanding processes. The possibility of obtaining spontaneous organization of separated components, whether they are molecules, polymers, nano- or micro-objects, into a larger functional unit, enables the development of ready-to-use plug and play devices and components at lower costs. Expanding the applicability of self-assembly approaches at the nanoscale to non-conventional substrates would open up new avenues towards multifunctional platforms customized for specific applications...
November 30, 2018: Nanoscale
Konstantinos Spanos, Tilo Kölbel, Fiona Rohlffs, Franziska Heidemann, Athanasios D Giannoukas, Sebastian E Debus, Nikolaos Tsilimparis
BACKGROUND: Residual patent false lumen (FL) after chronic type B (cTBAD) or type A aortic dissection (TAAD) treatment is independently associated with poor long-term outcome. The aim of our study was to present endovascular techniques and the existing experience of targeted false lumen (FL) thrombosis after cTBAD or type A TAAD treatment. MATERIAL AND METHODS: A systematic review was performed (PRISMA) searching in MEDLINE, CENTRAL, and Cochrane databases including studies reporting on targeted FL occlusion after cTBAD or TAAD...
November 26, 2018: Annals of Vascular Surgery
Majid Rezaei, Ahmad Reza Azimian, Ahmad Reza Pishevar
The electroosmosis effects at the interface of an aqueous NaCl solution and a charged silicon surface are studied using a molecular dynamics (MD) method. Considering a plug-like electroosmotic flow, we identified a thin interfacial layer in the immediate vicinity of the charged surface, where the flow velocity experiences almost linear spatial variations. The thickness of this interfacial layer is found to be linearly dependent on the surface charge density, with a negative slope which slightly depends on the surface hydrophobicity while being independent of the salt concentration, electric field strength, and orientation of the surface lattice...
November 29, 2018: Physical Chemistry Chemical Physics: PCCP
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