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Magnetic properties

Zhe Zhang, Na Niu, Xi Gao, Fuqin Han, Zhijun Chen, Shujun Li, Jian Li
Hypoxia is the main characteristic of tumor microenvironment, and the one of the key factors that cause the drug resistance of cancer cells for chemotherapy. Anticancer drug such as DOX cannot react with sufficient oxygen to produce reactive oxygen species (ROS) in hypoxic environment, which affects the therapeutic efficiency of the drug. In this work, we constructed a multi-functional nano-carrier (named as FeSiAuO) containing Fe3 O4 , mesoporous SiO2 and Au2 O3 with magnetic, large surface ratio and light induced oxygen production properties...
October 5, 2018: Colloids and Surfaces. B, Biointerfaces
Kandasamy Saravanakumar, Suresh Mandava, Ramachandran Chellia, Elango Jeevithan, Ravi Shankar Babu Yelamanchi, Deepthi Mandava, Wu Wen-Hui, Jong Kook Lee, Deog-Hwan Oh, Kandasamy Kathiresan, Myeong-Hyeon Wang
The present study aimed to purify and identify the metabolites from T. atroviride using high-performance liquid chromatography (HPLC) and 1 H and 13 C nuclear magnetic resonance spectrometer (NMR) followed by analyzing their toxicological, antibacterial and anticancer properties. This work identified two metabolites - TM1 and TM2. TM1 was in two forms: (i) 1, 3-dione-5, 5-dimethylcyclohexane; and, (ii) 2-enone-3hydroxy -5,5-dimethylcylohex, while TM2 was 4H-1,3-dioxin-4-one-2,3,6-trimethyl. These metabolites did not exhibit any irritant or allergic reaction as revealed by HET- CAM test...
October 10, 2018: Microbial Pathogenesis
Dingcheng Zhu, Sathi Roy, Ziyao Liu, Horst Weller, Wolfgang Parak, Neus Feliu
Tremendous efforts have been devoted to the development of future nanomedicines that can be specifically designed to incorporate responsive elements that undergo modification in structural properties upon external triggers. One potential use of such stimuli-responsive materials is to release encapsulated cargo upon excitation by an external trigger. Today, such stimuli-response materials allow for spatial and temporal tunability, which enables the controlled delivery of compounds in a specific and dose-dependent manner...
October 10, 2018: Advanced Drug Delivery Reviews
Xiaolin Cai, Zhili Zhu, Weiyang Yu, Chunyao Niu, Jianjun Wang, Baoji Wang, Xiaohua Li, Liwei Zhang, Ruiqi Zhao, Yu Jia
On the basis of density functional theory (DFT) calculations, we propose a stable two-dimensional (2D) monolayer phosphorus carbide (PC) with a GaSe-like structure, which has intriguing electronic and optical properties. Our calculated results show that this 2D monolayer structure is more stable than the other allotropes predicted by Tománek et al. [ Nano Lett., 2016, 16, 3247⁻3252 ]. More importantly, this structure exhibits superb optical absorption, which can be mainly attributed to its direct band gap of 2...
October 11, 2018: Materials
Jing Xu, Haiying Wang, Zhongpo Zhou, Zhaorui Zou
In this work, undoped, N-doped, WO₃-loaded undoped, and WO₃-loaded with N-doped TiO₂ rutile single-crystal wafers were fabricated by direct current (DC) magnetron sputtering. N-doping into TiO₂ and WO₃ loading onto TiO₂ surface were used to increase and decrease oxygen vacancies. Various measurements were conducted to analyze the structural and magnetic properties of the samples. X-ray diffraction results showed that the N-doping and WO₃ loading did not change the phase of all samples. X-ray photoelectron spectroscopy results revealed that W element loaded onto rutile single-crystal wafers existed in the form of WO₃...
October 11, 2018: Materials
Kairuo Zhu, Changlun Chen, Haiyan Wang, Yi Xie, Muhammad Wakeel, Abdul Wahid, Xiaodong Zhang
Layered double oxides (LDO) and γ-Fe2 O3 have been demonstrated to be promising adsorbents to remove radioactive elements from aqueous media. Herein, magnetic γ-Fe2 O3 nanoparticles decoration onto porous layered double oxides belts (γ-Fe2 O3 /LDO) were fabricated by in situ solid-state thermolysis technique combined with Fe(III)-loaded layered double hydroxides as a precursor. The microstructure, chemical composition, and magnetic properties of γ-Fe2 O3 /LDO were characterized in detail. The as-obtained γ-Fe2 O3 /LDO was employed as an adsorbent for the elimination of U(VI) from water...
October 4, 2018: Journal of Colloid and Interface Science
John W Hickey, Ariel Y Isser, Fernando P Vicente, Samuel B Warner, Hai-Quan Mao, Jonathan P Schneck
Magnetic particles can enrich desired cell populations to aid in understanding cell-type functions and mechanisms, diagnosis, and therapy. As cells are heterogeneous in ligand type, location, expression, and density, careful consideration of magnetic particle design for positive isolation is necessary. Antigen-specific immune cells have low frequencies, which has made studying, identifying, and utilizing these cells for therapy a challenge. Here we demonstrate the importance of magnetic particle design based on the biology of T cells...
September 28, 2018: Biomaterials
Emma Sprooten, Rafael O'Halloran, Juliane Dinse, Won Hee Lee, Dominik Andeas Moser, Gaelle Eve Doucet, Morgan Goodman, Hannah Krinsky, Alejandro Paulino, Alexander Rasgon, Evan Leibu, Priti Balchandani, Matilde Inglese, Sophia Frangou
BACKGROUND: Intracortical myelin is a key determinant of neuronal synchrony and plasticity that underpin optimal brain function. Magnetic resonance imanging (MRI) facilitiates the examination of intracortical myelin but presents with methodological challenges. Here we describe a whole-brain approach for the in vivo investigation of intracortical myelin in the human brain using ultra-high field MRI. METHODS: Twenty-five healthy adults were imaged in a 7 Tesla MRI scanner using diffusion-weighted imaging and a T1 -weighted sequence optimized for intracortical myelin contrast...
October 9, 2018: NeuroImage
Qianhao Xu, Tianyuan Zhang, Qiyue Wang, Xinchi Jiang, Ai Li, Ying Li, Ting Huang, Fangyuan Li, Ying Hu, Daishun Ling, Jianqing Gao
Recent advances in nanomaterials have made iron oxide nanoparticles (IONPs) as an innovative approach for the delivery of genes. However, the effectiveness of IONPs-assisted gene delivery is currently suffering from their poor uniformity, which not only exhibits detrimental effect on the magnetic property, but also leads to the poor reproducibility to maintain the optimal gene delivery. To this end, the present study developed extremely uniform 15 nm-sized IONPs with a good monodispersity in water phase. These ultra-uniform IONPs exhibit notable potentials for an efficient gene delivery to human mesenchymal stem cells (hMSCs) with the assistance of magnetic force, which partly owes to their abilities to facilitate the cellular uptake, as well as to induce the rapid DNA release and the following nuclear transport...
October 9, 2018: International Journal of Pharmaceutics
Zhe Wang, Yaou Duan, Yanwen Duan
Inspired by the bionics of marine mussels, polydopamine (PDA), a new polymer with unique physicochemical properties was discovered. Due to its simple preparation, good biocompatibility, unique drug-loading methods, PDA has attracted tremendous attentions in field of drug delivery and imaging, and the combination of chemotherapy and other therapies or diagnostic methods, such as photothermotherapy (PTT), photoacoustic imaging (PAI), magnetic resonance imaging (MRI), etc. As an excellent drug carrier in tumor targeted drug delivery system, the drug release behavior of drug-loaded PDA-based nanoparticles is also an important factor to be considered in the establishment of drug delivery systems...
October 9, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
Qing Jiang, Tao Tao, Hoa Phan, Yi Han, Tullimilli Y Gopalakrishna, Tun Seng Herng, Guangwu Li, Liu Yuan, Jun Ding, Chunyan Chi
Non-alternant, non-benzenoid π-conjugated polycyclic hydrocarbons (PHs) are expected to exhibit very different electronic properties from all-benzenoid PHs. Herein, we report the synthesis and physical properties of four derivatives (1a-b, 2a-b) of two azulene-fused s-indacene isomers, the diazuleno[2,1-a:2',1'-g]-s-indacene (DAI-1) and diazuleno[2,1-a:1',2'-h]-s-indacene (DAI-2). The backbone of both isomers contains 28 πe and is a 7-5-5-6-5-5-7 fused ring system. X-ray crystallographic analysis, NMR spectra, and theoretical calculations (ACID, NICS) reveal a structure with two aromatic azulene units fused with a central anti-aromatic s-indacene moiety...
October 12, 2018: Angewandte Chemie
Hui Wang, Xiaoling Xu, Yimin Jiang, Pengfei Yao, Bo Li, Huahong Zou, Jinglin Zhou, Zilu Chen
The reactions of 3,3'-bis(5-mercapto-1,2,4-triazole) with Co(ii) and Ni(ii) ions, respectively, gave two nanospheric mixed-valence icosanuclear cage-like complexes [M20L12](SO4)2·6DMF·CH3OH·3H2O (M = Co, 1; Ni, 2) with the in situ generated oxalyldithiosemicarbazide (H4L) as ligand. The eight octahedral M(ii) ions and twelve square-planar M(iii) ions in the two complexes are linked by twelve three-connecting linkers of L4- to build an icosanuclear [MII8MIII12L12]4+ nanocage with an inner cubic MII8 cage core...
October 12, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
Annalisa Gison, Stefano Bonassi, Federica Rizza, Salvatore Giaquinto
BACKGROUND: Personality traits have gained interest in the field of disability and stress, because they may either prompt or deny compliance. They can also foster motivation and influence outcome. Parkinson disease (PD) is a disabling and stressful condition that requires coping strategies and rehabilitation plans. Three constructs and their relative scales have been a matter of investigation, namely Dispositional Optimism (DO), Locus-of-Control (LOC), and Sense-of- Coherence (SOC). AIM: The present study compared the psychometric properties of three constructs in Parkinson's Disease (PD)...
October 10, 2018: European Journal of Physical and Rehabilitation Medicine
Xue Xiao, Liping Dong, Yi-Zhou Wang, Peng-Ye Wang, Ming Li, Guohong Li, Ping Chen, Wei Li
The accessibility of genomic DNA, as a key determinant of gene-related processes, is dependent on the packing density and structural dynamics of chromatin fiber. However, due to the highly dynamic and heterogeneous properties of chromatin fiber, it is technically challenging to study these properties of chromatin. Here, we report a strategy for dissecting the dynamics of chromatin fibers based on single-molecule magnetic tweezers. Using magnetic tweezers, we can manipulate the chromatin fiber and trace its extension during the folding and unfolding process under tension to investigate the dynamic structural transitions at single-molecule level...
2018: Biophysics Reports
Di S Wei, Toeno van der Sar, Seung Hwan Lee, Kenji Watanabe, Takashi Taniguchi, Bertrand I Halperin, Amir Yacoby
Spin waves are collective excitations of magnetic systems. An attractive setting for studying long-lived spin-wave physics is the quantum Hall (QH) ferromagnet, which forms spontaneously in clean two-dimensional electron systems at low temperature and in a perpendicular magnetic field. We used out-of-equilibrium occupation of QH edge channels in graphene to excite and detect spin waves in magnetically ordered QH states. Our experiments provide direct evidence for long-distance spin-wave propagation through different ferromagnetic phases in the N = 0 Landau level, as well as across the insulating canted antiferromagnetic phase...
October 12, 2018: Science
Arold Jorel Tsetegho Sokeng, Anatoly P Sobolev, Arianna Di Lorenzo, Jianbo Xiao, Luisa Mannina, Donatella Capitani, Maria Daglia
The metabolite profiling of extracts from Adansonia digitata L. (baobab) fruit pulp and leaf, and the quantification of their major components, was conducted by means of reverse-phase, high-performance liquid chromatography with photodiode array detection, coupled to electrospray ion-trap mass spectrometry (RP-HPLC-PDA-ESI-MS/MS) and high field nuclear magnetic resonance (NMR) spectroscopy. Water-soluble metabolites from chemical classes including sugars, amino acids, organic acids, and phenolic compounds, were identified, in addition to metabolites soluble in organic solvents such as triacylglycerides, sterols, and fatty acids, and most of these were quantified...
January 30, 2019: Food Chemistry
Mingrong Cheng, Daxi Ma, Kangkang Zhi, Baochi Liu, Weiping Zhu
BACKGROUND/AIMS: Our previous study found that a nanoparticle drug delivery system that operates as a drug carrier and controlled release system not only improves the efficacy of the drugs but also reduces their side effects. However, this system could not efficiently target hepatoma cells. The aim of this study was to synthesize biotin-modified galactosylated chitosan nanoparticles (Bio-GC) and evaluate their characteristics in vitro and in vivo. METHODS: Bio-GC nanomaterials were synthesized, and confirmed by fourier transform infrared spectroscopy (FT-IR) and hydrogen-1 nuclear magnetic resonance (1H-NMR)...
October 11, 2018: Cellular Physiology and Biochemistry
Ze Wang, Jian Zhang, Di Cui, Jun Xie, Mengye Lyu, Edward Hui, Ed Wu
OBJECTIVE: Magnetic resonance fingerprinting (MRF) is a new technique for simultaneously quantifying multiple MR parameters using one temporally resolved MR scan. In MRF, MR signal is manipulated to have distinct temporal behavior with regard to different combinations of the underlying MR parameters and across spatial regions. The temporal behavior of acquired MR signal is then used as a key to find its unique counterpart in a MR signal dictionary. The dictionary generation and searching (DGS) process represents the most important part of MRF, which however can be intractable because of the disk space requirement and the computational demand exponentially increases with the number of MR parameters, spatial coverage, and spatial resolution...
October 9, 2018: IEEE Transactions on Bio-medical Engineering
Jee Soo Chang, Sunghyun Kim, Ha-Jun Sung, Jegyeong Yeon, Kee Joo Chang, Xiaoqin Li, Suenne Kim
The ability to create graphene nanoribbons with atomically sharp edges is important for various graphene applications because these edges significantly influence the overall electronic properties and support unique magnetic edge states. The discovery of graphene self-folding induced by traveling wave excitation through atomic force microscope scanning under a normal force of less than 15 nN is reported. Most remarkably, the crystallographic direction of self-folding may be either along a chosen direction defined by the scan line or along the zigzag or armchair direction in the presence of a pre-existing crack in the vicinity...
October 11, 2018: Small
Xiaozhang Zhang, Gang Zhao, Yuan Cao, Zeeshan Haider, Meng Wang, Jianping Fu
Constructs of magnetic nanocomposite hydrogels microencapsulated with stem cells are of great interest as smart materials for tissue engineering and regenerative medicine. Due to the short shelf life of such biocomposites at an ambient temperature, their long-term storage and banking at cryogenic temperatures are essential for the "off-the-shelf" availability of such biocomposites for widespread clinical applications. However, high-quality cryogenic recovery of stem cell-nanocomposite hydrogel constructs has not yet been achieved due to the damage to cells and/or microstructures of hydrogel constructs caused by ice formation, particularly during warming from cryogenic temperatures...
October 11, 2018: Biomaterials Science
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