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Reactive Airway Dysfunction Syndrome

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https://www.readbyqxmd.com/read/27617449/vascular-endothelial-dysfunction-caused-by-oxidative-stress-is-a-predictor-factor-for-complications-of-obstructive-sleep-apnea-syndrome
#1
K Kilic, B Aktan, M Sedat-Sakat, A Kızıltunç, O Yoruk
Objective: Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive episodes of upper airway obstruction that occur during sleep which leads to cardiovascular, neurovascular and metabolic diseases. The mechanisms of complications in these patients are unclear. In this report, we aimed to determine the cause of oxidative imbalance in patients with OSAS and to evaluate the vascular endothelial dysfunction as a suspect for complications of the disease. Materials and Methods: Fifty patients diagnosed as moderate or severe OSAS (AHI > 15) by polysomnography and 50 healthy volunteers are included in the study...
February 15, 2016: West Indian Medical Journal
https://www.readbyqxmd.com/read/27614085/orthotopic-tracheal-transplantation-using-human-bronchus-an-original-xenotransplant-model-of-obliterative-airway-disorder
#2
Julien Guihaire, Ryo Itagaki, Mandy Stubbendorff, Xiaoqin Hua, Tobias Deuse, Sebastian Ullrich, Elie Fadel, Peter Dorfmüller, Robert C Robbins, Hermann Reichenspurner, Udo Schumacher, Sonja Schrepfer
Bronchiolitis obliterans syndrome (BOS) is a main cause of allograft dysfunction and mortality after lung transplantation (LTx). A better understanding of BOS pathogenesis is needed to overcome this treatment-refractory complication. Orthotopic tracheal transplantation using human bronchus was performed in Brown Norway (BN) and nude (RNU) rats. Allografts were recovered in both strains at Day 7 (BN7 , n = 6; RNU7 , n = 7) or Day 28 (BN28 , n = 6; RNU28 , n = 6). Immune response of the host against the bronchial graft was assessed...
September 10, 2016: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/27316915/french-intensive-care-society-international-congress-r%C3%A3-animation-2016
#3
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
https://www.readbyqxmd.com/read/27281642/then-and-now-reactive-airways-dysfunction-syndrome
#4
Stuart M Brooks
No abstract text is available yet for this article.
June 2016: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/26316731/sex-differences-of-continuous-positive-airway-pressure-treatment-on-flow-mediated-dilation-in-patients-with-obstructive-sleep-apnea-syndrome
#5
Anastasios Kallianos, Athanasios Panoutsopoulos, Christoforos Mermigkis, Konstantinos Kostopoulos, Chrysanthi Papamichail, Ioannis Kokkonouzis, Christoforos Kostopoulos, Ioannis Nikolopoulos, Antonis Papaiwannou, Sofia Lampaki, John Organtzis, Georgia Pitsiou, Paul Zarogoulidis, Georgia Trakada
INTRODUCTION: There is growing research evidence suggesting the presence of endothelial dysfunction and systemic inflammation in patients with obstructive sleep apnea syndrome (OSAS). Continuous positive airway pressure (CPAP) is the most effective method for treating OSAS; nonetheless, the effects of CPAP on the aforementioned pathophysiologic pathways as well as on the systemic disease that result or coexist with the OSAS remain elusive. AIM: To assess the effect of 3-month CPAP therapy on endothelial-dependent dilation, plasma levels of inflammatory markers, blood pressure (BP), and glucose control on male and female patients with OSAS...
2015: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/25622738/-association-between-inflammation-and-cognitive-function-and-effects-of-continuous-positive-airway-pressure-treatment-in-obstructive-sleep-apnea-hypopnea-syndrome
#6
Li Sun, Rui Chen, Jing Wang, Yanlin Zhang, Jie Li, Wanda Peng, Chunfeng Liu
OBJECTIVE: To explore the association between serum inflammation levels and cognitive function in patients with obstructive sleep apnea-hypopnea syndromes (OSAHS) and evaluate the effects of continuous positive airway pressure treatment (CPAP) on serum inflammation levels and cognitive function. METHODS: A total of 139 eligible patients were monitored by overnight polysomnography (PSG) at Sleep Center, Second Affiliated Hospital, Soochow University from June 2011 to April 2013...
December 2, 2014: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/25302516/corticosteroids-therapy-in-pediatric-acute-respiratory-distress-syndrome
#7
Maria Clara de Magalhães Barbosa, Arnaldo Prata Barbosa, Patricia Rieken Macêdo Rocco
The use of corticosteroids in acute lung injury and acute respiratory distress syndrome is one of the most controversial issues in the literature. However, acute lung injury/acute respiratory distress syndrome studies are restricted to adults, despite the widespread use of corticosteroid for hyper-reactive respiratory airway diseases in children. This review aimed to describe experimental and clinical evidence for corticosteroid therapy in acute lung injury/acute respiratory distress syndrome and to point out the risks and benefits of its use in pediatrics...
December 2010: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/25137406/r-134a-1-1-1-2-tetrafluoroethane-inhalation-induced-reactive-airways-dysfunction-syndrome
#8
Viral Doshi, Nang Kham, Shreedhar Kulkarni, Kent Kapitan, Joseph Henkle, Peter White
R-134a (1,1,1,2-tetrafluoroethane) is widely used as a refrigerant and as an aerosol propellant. Inhalation of R-134a can lead to asphyxia, transient confusion, and cardiac arrhythmias. We report a case of reactive airways dysfunction syndrome secondary to R-134a inhalation. A 60-year-old nonsmoking man without a history of lung disease was exposed to an air conditioner refrigerant spill while performing repairs beneath a school bus. Afterward, he experienced worsening shortness of breath with minimal exertion, a productive cough, and wheezing...
May 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/24343122/irritant-induced-asthma-in-the-workplace
#9
REVIEW
Susan M Tarlo
Irritant-induced asthma in the workplace has been the focus of several articles in the past few years, and reviewed here. A clinical case definition is most readily associated with a single acute/accidental exposure to a presumed high concentration of an agent or agents expected to be irritant to the airways, as was initially reported with the subgroup Reactive Airways Dysfunction Syndrome (RADS). When most but not all criteria for RADS are met, then a diagnosis of irritant-induced asthma may also be considered to be "more probable than not"...
January 2014: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/24327000/endothelial-injury-markers-before-and-after-nasal-continuous-positive-airway-pressure-treatment-for-obstructive-sleep-apnoea-hypopnoea-syndrome
#10
Maria Wilczynska, Samuel Rice, Gareth Davies, Keir E Lewis
PURPOSE: The purpose of this study was to evaluate whether serum amyloid A (SAA), C-reactive protein (CRP), vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) levels are elevated in obstructive sleep apnoea hypopnoea syndrome (OSAHS), and whether they change following acute- and medium-term CPAP treatment. METHODS: Consecutive subjects (n = 40) referred to the Sleep Disordered Breathing Unit were included in the research...
September 2014: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/23969509/reactive-airways-dysfunction-syndrome-and-considerations-of-irritant-induced-asthma
#11
Stuart M Brooks
The Occupational Medicine Forum is prepared by the ACOEM Occupational and Environmental Medical Practice Committee and does not necessarily represent an official ACOEM position. The Forum is intended for health professionals and is not intended to provide medical or legal advice, including illness prevention, diagnosis or treatment, or regulatory compliance. Such advice should be obtained directly from a physician and/or attorney.
September 2013: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/23825894/first-reported-case-of-reactive-airway-dysfunction-syndrome-in-a-laborer-due-to-porcelain-tile-dust
#12
Tasleem Arif, Javid Ahmad Malik, Sheikh Shoib
Reactive airway dysfunction syndrome (RADS) is a type of non-immunologically mediated asthma-like disease. It usually occurs after a massive exposure to an irritating substance in the atmosphere in the form of smoke, fumes, gases, and vapor. Unlike bronchial asthma, there is no latency to the symptoms seen in RADS. A number of agents are known to cause RADS, but tile dust, as an etiological agent, has not been previously reported. We report a 45-year-old male laborer, who presented with an acute onset of cough, chest tightness, breathlessness, and audible wheeze after his first time exposure to porcelain tile dust within 5 hours of exposure...
June 2013: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/23777985/heparin-binding-epidermal-growth-factor-like-growth-factor-attenuates-acute-lung-injury-and-multiorgan-dysfunction-after-scald-burn
#13
Jeffrey Lutmer, Daniel Watkins, Chun-Liang Chen, Markus Velten, Gail Besner
BACKGROUND: Impaired gut barrier function and acute lung injury (ALI) are significant components of the multiorgan dysfunction syndrome that accompanies severe burns. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) has been shown to reduce inflammation, preserve gut barrier function, and protect the lungs from acute injury in several models of intestinal injury; however, comparable effects of HB-EGF after burn injury have never been investigated. The present studies were based on the hypothesis that HB-EGF would reduce the severity of ALI and multiorgan dysfunction after scald burns in mice...
November 2013: Journal of Surgical Research
https://www.readbyqxmd.com/read/23590017/respiratory-health-effect-of-persons-accidentally-expose-to-high-concentration-of-chlorine-gas
#14
Nitipatana Chierakul, Nuttapol Rittayamai, Prachya Passaranon, Charttiwut Chamchod, Bralee Suntiwuth
OBJECTIVE: To evaluate the short term and long term respiratory health effects of subjects who accidentally exposed to high concentration of chlorine gas. MATERIAL AND METHOD: There was an accidental leakage of sodium hypochlorite from an industrial factory in Rayong province in June 2010. Medical records of those who developed severe symptoms after exposed to high concentration of chlorine gas were reviewed. Prospective observational study was conducted after hospital discharge by interviewing with respiratory health questionnaires, physical examination, spirometry, methacholine challenge test, and home peak expiratory flow (PEF) monitoring at 2, 5 and 8 months after the event...
February 2013: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/23478950/third-nerve-palsy-associated-with-preeclampsia-and-hellp-syndrome
#15
Anuntapon Chutatape, Wendy H L Teoh
Preeclampsia can cause myriad organ dysfunction, including cranial nerve palsies that pose diagnostic and management dilemmas. We present an unusual case of third nerve palsy, (presenting as diplopia, ptosis) with hypertension, hyperreflexia, proteinuria, easy bruising in a parturient at 34 + 6/52 weeks of twins gestation. She was treated as for severe preeclampsia and HELLP syndrome; intravenous magnesium sulphate and labetalol commenced and emergent cesarean delivery performed under general anesthesia due to concerns of low platelets and for airway protection should her glascow coma scale (GCS) deteriorate...
October 2013: Journal of Anesthesia
https://www.readbyqxmd.com/read/23466955/anti-inflammatory-treatment-of-meconium-aspiration-syndrome-benefits-and-risks
#16
REVIEW
Daniela Mokra, Juraj Mokry, Ingrid Tonhajzerova
Meconium aspiration syndrome (MAS) is a major cause of respiratory insufficiency in the term and post-term newborns. There are several pathomechanisms participating in this disorder, particularly the airway obstruction, surfactant dysfunction, inflammation, lung edema, pulmonary vasoconstriction and bronchoconstriction. Inflammatory changes resulting from meconium aspiration cause severe impairment of lung parenchyma and surfactant, and influence the reactivity of both vascular and airway smooth muscle. Therefore, anti-inflammatory drugs may be of benefit in the management of MAS...
June 1, 2013: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/23292295/accidental-exposure-to-polychlorinated-biphenyls-pcb-in-waste-cargo-after-heavy-seas-global-waste-transport-as-a-source-of-pcb-exposure
#17
Lygia Therese Budnik, Ralf Wegner, Ulrich Rogall, Xaver Baur
OBJECTIVES: After cargo with PCB-containing transformer oil waste was damaged in heavy seas, the vessel crew exposed to PCB developed itching and acne-form eruption of the skin. The objective of our study was to analyse this work-related incident and its effects on health. METHODS: Air and wipe test samples were taken in the ship for analysis of PCB (28/52/101/138/153/180); clinical investigations of all seafarers (n = 6) included lung function, chest X-ray, clinical chemistry and biomonitoring (plasma PCBs, chlorophenols in urine) measured after a latency of 7 weeks...
February 2014: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/23222372/chlorine-gas-release-associated-with-employee-language-barrier-arkansas-2011
#18
(no author information available yet)
On June 27, 2011, a worker at a poultry processing plant in Arkansas began to pour sodium hypochlorite into a 55-gallon drum that contained residual acidic antimicrobial solution. When the sodium hypochlorite reacted with the solution, greenish-yellow chlorine gas was released into the small room where the drum was located and then spread into the plant, where approximately 600 workers were present. These workers promptly were evacuated. Chlorine is a respiratory irritant and can produce symptoms ranging from mild eye, nose, and throat irritation to severe inflammation of the lung, which can lead to death...
December 7, 2012: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/23146759/inhalation-of-chlorine-causes-long-standing-lung-inflammation-and-airway-hyperresponsiveness-in-a-murine-model-of-chemical-induced-lung-injury
#19
Sofia Jonasson, Bo Koch, Anders Bucht
Chlorine is highly irritating when inhaled, and is a common toxic industrial gas causing tissue damage in the airways followed by an acute inflammatory response. In this study, we investigated mechanisms by which chlorine exposure may cause reactive airways dysfunction syndrome (RADS) and we examined the dose-dependency of the development of symptoms. Mice were exposed to 50 or 200 ppm Cl(2) during a single 15 min exposure in a nose-only container. The experiment terminated 2, 6, 12, 24, 48, 72 h and 7, 14, 28 and 90 days post exposure...
January 7, 2013: Toxicology
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