Read by QxMD icon Read

Reactive Airway Dysfunction Syndrome

Mark A D'Andrea, G Kesava Reddy
Background: The purpose of this study was to assess the long-term adverse health effects of the 2010 Deepwater Horizon Gulf oil spill exposure in workers who participated in its cleanup work. Methods: Medical charts of both the oil spill exposed and unexposed subjects were reviewed. The changes in the white blood cells, platelets, hemoglobin, hematocrit, blood urea nitrogen, creatinine, alkaline phosphatase (ALP), aspartate amino transferase (AST), alanine amino transferase (ALT) levels, as well as their pulmonary and cardiac functions were evaluated...
2018: Frontiers in Public Health
Wojciech Trzepizur, Vanessa Bironneau, Sylvain Recoquillon, Pascaline Priou, Nicole Meslier, Jean-François Hamel, Samir Henni, Astrid Darsonval, Khaled Messaoudi, Maria Carmen Martínez, Ramaroson Andriantsitohaina, Frédéric Gagnadoux
Background: Endothelial dysfunction, a pathophysiologic determinant of atherogenesis, has been found to occur in obstructive sleep apnea syndrome (OSA) and is improved by continuous positive airway pressure (CPAP). However, the efficacy of CPAP therapy is limited by variable adherence. Alternative treatment strategies are needed. The impact of polyphenols on endothelial function has never been evaluated in OSA. Objective: We evaluated the impact of 1-mo supplementation with grape juice polyphenols (GJPs) on the reactive hyperemia index (RHI), a validated measure of endothelial function in patients with severe OSA...
April 1, 2018: Journal of Nutrition
Donald W Cockcroft
Environmental factors which cause asthma are those that induce airway inflammation with eosinophils (more common) or neutrophils along with airway hyperresponsiveness (AHR). The most common of these (indeed the most common cause of asthma) are IgE-mediated inhalant allergen exposures. Allergen-induced AHR and inflammation are both associated with the allergen-induced late asthmatic response (LAR). Although allergens were previously recognized only as causes of symptoms and bronchoconstriction in asthmatics, we now appreciate them as causes of the fundamental pathophysiologic features of asthma...
February 2018: Seminars in Respiratory and Critical Care Medicine
Muhammad Kashif, Tushi Singh, Ahsan Aslam, Misbahuddin Khaja
Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. Various clinical conditions can mimic asthma, such as foreign body aspiration, subglottic stenosis, congestive heart failure, diffuse panbronchiolitis, aortic arch anomalies, reactive airway dysfunction syndrome, chronic obstructive pulmonary disease, retrosternal goiter, vocal cord tumors, other airway tumors, and vocal cord dysfunction. Upper airway obstruction can be a life-threatening emergency. Here, we present the case of a 58-year-old female with recurrent hospital visits for wheezing and exacerbations of asthma, who was later found to have a vocal cord nodule confirmed to be squamous cell carcinoma, which was mimicking like asthma...
2017: SAGE Open Medical Case Reports
K Kilic, B Aktan, M Sedat-Sakat, A Kızıltunç, O Yoruk
Objective: Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive episodes of upper airway obstruction that occur during sleep which leads to cardiovascular, neurovascular and metabolic diseases. The mechanisms of complications in these patients are unclear. In this report, we aimed to determine the cause of oxidative imbalance in patients with OSAS and to evaluate the vascular endothelial dysfunction as a suspect for complications of the disease. Materials and Methods: Fifty patients diagnosed as moderate or severe OSAS (AHI > 15) by polysomnography and 50 healthy volunteers are included in the study...
February 15, 2016: West Indian Medical Journal
Julien Guihaire, Ryo Itagaki, Mandy Stubbendorff, Xiaoqin Hua, Tobias Deuse, Sebastian Ullrich, Elie Fadel, Peter Dorfmüller, Robert C Robbins, Hermann Reichenspurner, Udo Schumacher, Sonja Schrepfer
Bronchiolitis obliterans syndrome (BOS) is a main cause of allograft dysfunction and mortality after lung transplantation (LTx). A better understanding of BOS pathogenesis is needed to overcome this treatment-refractory complication. Orthotopic tracheal transplantation using human bronchus was performed in Brown Norway (BN) and nude (RNU) rats. Allografts were recovered in both strains at Day 7 (BN7 , n = 6; RNU7 , n = 7) or Day 28 (BN28 , n = 6; RNU28 , n = 6). Immune response of the host against the bronchial graft was assessed...
December 2016: Transplant International: Official Journal of the European Society for Organ Transplantation
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
Stuart M Brooks
No abstract text is available yet for this article.
June 2016: Journal of Occupational and Environmental Medicine
Anastasios Kallianos, Athanasios Panoutsopoulos, Christoforos Mermigkis, Konstantinos Kostopoulos, Chrysanthi Papamichail, Ioannis Kokkonouzis, Christoforos Kostopoulos, Ioannis Nikolopoulos, Antonis Papaiwannou, Sofia Lampaki, John Organtzis, Georgia Pitsiou, Paul Zarogoulidis, Georgia Trakada
INTRODUCTION: There is growing research evidence suggesting the presence of endothelial dysfunction and systemic inflammation in patients with obstructive sleep apnea syndrome (OSAS). Continuous positive airway pressure (CPAP) is the most effective method for treating OSAS; nonetheless, the effects of CPAP on the aforementioned pathophysiologic pathways as well as on the systemic disease that result or coexist with the OSAS remain elusive. AIM: To assess the effect of 3-month CPAP therapy on endothelial-dependent dilation, plasma levels of inflammatory markers, blood pressure (BP), and glucose control on male and female patients with OSAS...
2015: Clinical Interventions in Aging
Li Sun, Rui Chen, Jing Wang, Yanlin Zhang, Jie Li, Wanda Peng, Chunfeng Liu
OBJECTIVE: To explore the association between serum inflammation levels and cognitive function in patients with obstructive sleep apnea-hypopnea syndromes (OSAHS) and evaluate the effects of continuous positive airway pressure treatment (CPAP) on serum inflammation levels and cognitive function. METHODS: A total of 139 eligible patients were monitored by overnight polysomnography (PSG) at Sleep Center, Second Affiliated Hospital, Soochow University from June 2011 to April 2013...
December 2, 2014: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Maria Clara de Magalhães Barbosa, Arnaldo Prata Barbosa, Patricia Rieken Macêdo Rocco
The use of corticosteroids in acute lung injury and acute respiratory distress syndrome is one of the most controversial issues in the literature. However, acute lung injury/acute respiratory distress syndrome studies are restricted to adults, despite the widespread use of corticosteroid for hyper-reactive respiratory airway diseases in children. This review aimed to describe experimental and clinical evidence for corticosteroid therapy in acute lung injury/acute respiratory distress syndrome and to point out the risks and benefits of its use in pediatrics...
December 2010: Revista Brasileira de Terapia Intensiva
Viral Doshi, Nang Kham, Shreedhar Kulkarni, Kent Kapitan, Joseph Henkle, Peter White
R-134a (1,1,1,2-tetrafluoroethane) is widely used as a refrigerant and as an aerosol propellant. Inhalation of R-134a can lead to asphyxia, transient confusion, and cardiac arrhythmias. We report a case of reactive airways dysfunction syndrome secondary to R-134a inhalation. A 60-year-old nonsmoking man without a history of lung disease was exposed to an air conditioner refrigerant spill while performing repairs beneath a school bus. Afterward, he experienced worsening shortness of breath with minimal exertion, a productive cough, and wheezing...
May 2016: American Journal of Therapeutics
Susan M Tarlo
Irritant-induced asthma in the workplace has been the focus of several articles in the past few years, and reviewed here. A clinical case definition is most readily associated with a single acute/accidental exposure to a presumed high concentration of an agent or agents expected to be irritant to the airways, as was initially reported with the subgroup Reactive Airways Dysfunction Syndrome (RADS). When most but not all criteria for RADS are met, then a diagnosis of irritant-induced asthma may also be considered to be "more probable than not"...
January 2014: Current Allergy and Asthma Reports
Maria Wilczynska, Samuel Rice, Gareth Davies, Keir E Lewis
PURPOSE: The purpose of this study was to evaluate whether serum amyloid A (SAA), C-reactive protein (CRP), vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) levels are elevated in obstructive sleep apnoea hypopnoea syndrome (OSAHS), and whether they change following acute- and medium-term CPAP treatment. METHODS: Consecutive subjects (n = 40) referred to the Sleep Disordered Breathing Unit were included in the research...
September 2014: Sleep & Breathing, Schlaf & Atmung
Stuart M Brooks
The Occupational Medicine Forum is prepared by the ACOEM Occupational and Environmental Medical Practice Committee and does not necessarily represent an official ACOEM position. The Forum is intended for health professionals and is not intended to provide medical or legal advice, including illness prevention, diagnosis or treatment, or regulatory compliance. Such advice should be obtained directly from a physician and/or attorney.
September 2013: Journal of Occupational and Environmental Medicine
Tasleem Arif, Javid Ahmad Malik, Sheikh Shoib
Reactive airway dysfunction syndrome (RADS) is a type of non-immunologically mediated asthma-like disease. It usually occurs after a massive exposure to an irritating substance in the atmosphere in the form of smoke, fumes, gases, and vapor. Unlike bronchial asthma, there is no latency to the symptoms seen in RADS. A number of agents are known to cause RADS, but tile dust, as an etiological agent, has not been previously reported. We report a 45-year-old male laborer, who presented with an acute onset of cough, chest tightness, breathlessness, and audible wheeze after his first time exposure to porcelain tile dust within 5 hours of exposure...
June 2013: Iranian Journal of Medical Sciences
Jeffrey Lutmer, Daniel Watkins, Chun-Liang Chen, Markus Velten, Gail Besner
BACKGROUND: Impaired gut barrier function and acute lung injury (ALI) are significant components of the multiorgan dysfunction syndrome that accompanies severe burns. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) has been shown to reduce inflammation, preserve gut barrier function, and protect the lungs from acute injury in several models of intestinal injury; however, comparable effects of HB-EGF after burn injury have never been investigated. The present studies were based on the hypothesis that HB-EGF would reduce the severity of ALI and multiorgan dysfunction after scald burns in mice...
November 2013: Journal of Surgical Research
Nitipatana Chierakul, Nuttapol Rittayamai, Prachya Passaranon, Charttiwut Chamchod, Bralee Suntiwuth
OBJECTIVE: To evaluate the short term and long term respiratory health effects of subjects who accidentally exposed to high concentration of chlorine gas. MATERIAL AND METHOD: There was an accidental leakage of sodium hypochlorite from an industrial factory in Rayong province in June 2010. Medical records of those who developed severe symptoms after exposed to high concentration of chlorine gas were reviewed. Prospective observational study was conducted after hospital discharge by interviewing with respiratory health questionnaires, physical examination, spirometry, methacholine challenge test, and home peak expiratory flow (PEF) monitoring at 2, 5 and 8 months after the event...
February 2013: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Anuntapon Chutatape, Wendy H L Teoh
Preeclampsia can cause myriad organ dysfunction, including cranial nerve palsies that pose diagnostic and management dilemmas. We present an unusual case of third nerve palsy, (presenting as diplopia, ptosis) with hypertension, hyperreflexia, proteinuria, easy bruising in a parturient at 34 + 6/52 weeks of twins gestation. She was treated as for severe preeclampsia and HELLP syndrome; intravenous magnesium sulphate and labetalol commenced and emergent cesarean delivery performed under general anesthesia due to concerns of low platelets and for airway protection should her glascow coma scale (GCS) deteriorate...
October 2013: Journal of Anesthesia
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"