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https://www.readbyqxmd.com/read/30093159/new-high-blood-pressure-guidelines-back-on-track-with-lower-treatment-goals-but-implementation-challenges-abound
#1
EDITORIAL
Randall S Stafford
The recently released 2017 High Blood Pressure Guidelines depart from past guidelines in both their approach and recommendations. Developed by multiple health organizations, including the American College of Preventive Medicine, the guidelines continue to define normal blood pressure as <120/80 mmHg, but now define hypertension as ≥130/80 mmHg (previously ≥140/90 mmHg). This change categorizes 101 million Americans (46% of adults) as hypertensive (compared to 32% previously). The guidelines rely heavily on findings from the Systolic Blood Pressure Intervention Trial (SPRINT)...
August 6, 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/30089130/implication-of-mir-612-and-mir-1976-in-the-regulation-of-tp53-and-cd40-and-their-relationship-in-the-response-to-specific-weight-loss-diets
#2
Marcos Garcia-Lacarte, J Alfredo Martinez, M Angeles Zulet, Fermin I Milagro
BACKGROUND: Non-coding RNAs (i.e., miRNAs) play a role in the development of obesity and related comorbidities and the regulation of body weight. OBJECTIVE: To identify candidate miRNA biomarkers throughout omics approaches in order to predict the response to specific weight-loss dietary treatments. DESIGN: Genomic DNA and cDNA isolated from white blood cells of a subset from the RESMENA nutritional intervention study (Low-responders (LR) vs High-responders (HR)) was hybridized in Infinium Human Methylation450 BeadChip and in Illumina Human HT-12 v4 gene expression BeadChips arrays respectively...
2018: PloS One
https://www.readbyqxmd.com/read/30088659/the-effect-of-shift-work-on-eating-habits-a-systematic-review
#3
Renata Vieira Souza, Roberta Aguiar Sarmento, Jussara Carnevale de Almeida, Raquel Canuto
Objective This systematic review aimed to evaluate the association between shift work and eating habits. Methods The protocol was registered in PROSPERO (number 42015024680). PubMed, EMBASE, Scopus, and Web of Science were searched for published reports. Of 2432 identified articles, 33 observational studies met the inclusion criteria. Their methodological approaches were assessed using the Newcastle-Ottawa Scale. Data were extracted using a standardized form. Studies were considered to have a low or a high risk of bias according to a percentage score of quality...
August 8, 2018: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/30082650/phenolic-compounds-isolated-from-olive-oil-as-nutraceutical-tools-for-the-prevention-and-management-of-cancer-and-cardiovascular-diseases
#4
REVIEW
Patricia Reboredo-Rodríguez, Alfonso Varela-López, Tamara Y Forbes-Hernández, Massimiliano Gasparrini, Sadia Afrin, Danila Cianciosi, Jiaojiao Zhang, Piera Pia Manna, Stefano Bompadre, José L Quiles, Maurizio Battino, Francesca Giampieri
Non-communicable diseases (NCDs) have become the largest contributor to worldwide morbidity and mortality. Among them, cancer and cardiovascular diseases (CVDs) are responsible for a 47% of worldwide mortality. In general, preventive approaches modifying lifestyle are more cost-effective than treatments after disease onset. In this sense, a healthy diet could help a range of NCDs, such as cancer and CVDs. Traditional Mediterranean Diet (MD) is associated by the low-prevalence of certain types of cancers and CVDs, where olive oil plays an important role...
August 6, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/30072112/diet-induced-weight-loss-alone-or-combined-with-exercise-in-overweight-or-obese-people-with-knee-osteoarthritis-a-systematic-review-and-meta-analysis
#5
Michelle Hall, Birgit Castelein, Ruth Wittoek, Patrick Calders, Ans Van Ginckel
OBJECTIVES: The purposes were to (i) determine the effect of diet-only treatments and combined diet and exercise treatments on pain and physical function and (ii) explore the effect of these treatments on inflammatory biomarkers in overweight and obese adults with knee osteoarthritis. METHODS: Five electronic databases were searched until March 2017. Randomised controlled trials investigating the effect of non-surgical non-pharmacological weight loss treatment, with or without exercise, on self-reported pain and/or physical function and/or inflammatory biomarkers were selected...
June 21, 2018: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/30063146/molar-incisor-hypomineralization-paediatricians-should-be-involved-as-well
#6
L Paglia
Tooth structure anomalies affect the deciduous or permanent dentition with varying degrees of severity, depending on the odontogenesis phase in which the disturbance factor occurs. Some forms are clearly increasing and becoming of common clinical observation, as is the case of MIH (Molar Incisor Hypomineralization) whose prevalence ranges from 3 to 25%. However, often stucture anomalies are still under-diagnosed. Early diagnosis should be within the reach of all clinicians (both dentist and non-dentist), and is essential for improving the treatment outcome and quality of life of affected patients...
September 2018: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/30057115/diet-induced-circadian-enhancer-remodeling-synchronizes-opposing-hepatic-lipid-metabolic-processes
#7
Dongyin Guan, Ying Xiong, Patricia C Borck, Cholsoon Jang, Paschalis-Thomas Doulias, Romeo Papazyan, Bin Fang, Chunjie Jiang, Yuxiang Zhang, Erika R Briggs, Wenxiang Hu, David Steger, Harry Ischiropoulos, Joshua D Rabinowitz, Mitchell A Lazar
Overnutrition disrupts circadian metabolic rhythms by mechanisms that are not well understood. Here, we show that diet-induced obesity (DIO) causes massive remodeling of circadian enhancer activity in mouse liver, triggering synchronous high-amplitude circadian rhythms of both fatty acid (FA) synthesis and oxidation. SREBP expression was rhythmically induced by DIO, leading to circadian FA synthesis and, surprisingly, FA oxidation (FAO). DIO similarly caused a high-amplitude circadian rhythm of PPARα, which was also required for FAO...
July 24, 2018: Cell
https://www.readbyqxmd.com/read/30055803/autophagy-is-involved-in-acetylshikonin-ameliorating-non-alcoholic-steatohepatitis-through-ampk-mtor-pathway
#8
Jiacheng Zeng, Banghao Zhu, Meiling Su
Acetylshikonin (AS), a naphthoquinone constituent derived from Lithospermum erythrorhizon, has been revealed various pharmacological activities including anti-oxidative, anti-inflammatory and antifertility effects. Our previous study has illuminated the effects of AS on preventing obesity and hepatic steatosis in db/db mice. However, the effects of AS and the molecular mechanisms for curing non-alcoholic steatohepatitis (NASH) have not yet been studied. Autophagy has been considered as a lysosomal degradative pathway responsible for the removal of cellular lipid droplets through a process called lipophagy, which is recognized as a potential therapeutic approach for NASH...
July 25, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/30045579/energy-use-and-carbon-footprint-of-the-tomato-production-in-heated-multi-tunnel-greenhouses-in-almeria-within-an-exporting-agri-food-system-context
#9
David Pérez Neira, Marta Soler Montiel, Manuel Delgado Cabeza, Alicia Reigada
Almeria (Spain) is one of the most important agricultural centers of vegetable cultivation in Europe. The search for technological innovation has led to the introduction of climate control systems in greenhouses in Almeria to improve productivity during the cold season. Up to now, no studies have analyzed the energy behavior of introducing this technology in this specific region. The objective of the present study is therefore to analyze the energy use and carbon footprint (CF) of the tomato production in heated multi-tunnel greenhouses in Almeria from a life cycle perspective (cradle to regional distribution center approach)...
July 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/30039478/body-length-determines-the-diet-and-niche-specialization-of-non-biting-midge-predator-tanypodinae-larvae-in-shallow-reservoirs
#10
H H L Saulino, S Trivinho-Strixino
The functional traits of species respond to environmental gradient changes, which, in turn, are responsible for the niche specialization of species. We analyzed the niche specialization of several Tanypodinae taxa (predatory non-biting midge, 4th instar, n = 693) along the depth zones of the water in six shallow tropical reservoirs. We measured the body length and diet composition of seven Tanypodinae larvae genus. Community-weighted mean (CWM) traits index was utilized to calculate the niche distribution of body length and diet composition...
July 24, 2018: Neotropical Entomology
https://www.readbyqxmd.com/read/30032630/role-of-the-pnpla3-polymorphism-rs738409-on-silymarin-vitamin-e-response-in-subjects-with-non-alcoholic-fatty-liver-disease
#11
Rocío Aller, Cristina Laserna, Miguel Ángel Rojo, Natalia Mora, Concepción García Sánchez, María Pina, Rebeca Sigüenza, Miguel Durà, David Primo, Olatz Izaola, Daniel de Luis
BACKGROUND: non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in developed countries. Lifestyle changes are the pillar of the treatment, although a pharmacological approach is sometimes required in the case of a failure to respond/adhere to the diet. OBJECTIVE: the aim of this study was to evaluate the effect of silymarin and the influence of the patatin-like phospholipase domain-containing protein 3 (PNPLA3) variant on the response to treatment in patients with NAFLD in a pilot study...
July 23, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/30030922/discrimination-factors-of-carbon-and-nitrogen-stable-isotopes-from-diet-to-hair-in-captive-large-arctic-carnivores-of-conservation-concern
#12
Vincent L'Hérault, Nicolas Lecomte, Marie-Hélène Truchon, Dominique Berteaux
RATIONALE: Stable isotope analysis is widely used to reconstruct diet, delineate trophic interactions, and determine energy pathways. Such ecological inferences are based on the idea that animals are, isotopically, what they eat but with a predictable difference between the isotopic ratio of a consumer and that of its diet, coined as the discrimination factor. Providing correct estimates of diet-consumer isotopic discrimination in controlled conditions is key for a robust application of the stable isotopes technique in the wild...
July 21, 2018: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/30029632/use-of-modified-diets-to-prevent-aspiration-in-oropharyngeal-dysphagia-is-current-practice-justified
#13
Shaun T O'Keeffe
BACKGROUND: Although modifying diets, by thickening liquids and modifying the texture of foods, to reduce the risk of aspiration has become central to the current management of dysphagia, the effectiveness of this intervention has been questioned. This narrative review examines, and discusses possible reasons for, the apparent discrepancy between the widespread use of modified diets in current clinical practice and the limited evidence base regarding the benefits and risks of this approach...
July 20, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/30026794/barriers-to-cardiovascular-disease-secondary-prevention-care-in-the-west-bank-palestine-a-health-professional-perspective
#14
Jane Collier, Hanna Kienzler
Background: Non-communicable diseases (NCDs) - including cardiovascular disease (CVD), cancer and diabetes - have become a significant global burden on health. Particularly concerning are CVD rates, causing approximately 18 million deaths worldwide every year. The statistics show that the disease is no longer a predominantly high-income country phenomenon, but affects, increasingly, countries in both developing regions and conflict-affected areas. In the occupied Palestinian territory (oPt), the focus of this article, CVD ranks top of ten NCD killers, accounting for approximately 37...
2018: Conflict and Health
https://www.readbyqxmd.com/read/30025959/non-pharmacologic-measures-for-gout-management-in-the-prospective-gospel-cohort-physicians-practice-and-patients-compliance-profiles
#15
Anthony Chapron, Typhaine Chopin, Maxime Esvan, Ea Hang-Korng, Frédéric Lioté, Pascal Guggenbuhl
OBJECTIVES: Gout management includes non-pharmacological measures (NPM). The main objective of this study was to describe the NPM proposed by physicians and their implementation by patients after 3-6 months. The secondary objective was to identify NPM compliance profiles among these patients. METHODS: Ancillary observational study using the GOSPEL French cohort of 1003 patients with gout, based on questionnaires for physicians and patients at inclusion and then after 3-6 months...
July 16, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/30022799/controlling-resistant-hypertension
#16
REVIEW
J David Spence
Resistant hypertension (failure to achieve target blood pressures with three or more antihypertensive drugs including a diuretic) is an important and preventable cause of stroke. Hypertension is highly prevalent in China (>60% of persons above age 65), and only ~6% of hypertensives in China are controlled to target levels. Most strokes occur among persons with resistant hypertension; approximately half of strokes could be prevented by blood pressure control. Reasons for uncontrolled hypertension include (1) non-compliance; (2) consumption of substances that aggravated hypertension, such as excess salt, alcohol, licorice, decongestants and oral contraceptives; (3) therapeutic inertia (failure to intensify therapy when target blood pressures are not achieved); and (4) diagnostic inertia (failure to investigate the cause of resistant hypertension)...
June 2018: Stroke and Vascular Neurology
https://www.readbyqxmd.com/read/30019784/extracellular-matrix-remodeling-in-the-liver-of-rats-subjected-to-dietary-choline-deprivation-and-or-thioacetamide-administration
#17
Hussam Al-Humadi, Ahmed Alhumadi, Rafal Al-Saigh, Athina Strilakou, Andreas Lazaris, Maria Gazouli, Charis Liapi
Choline deprivation is a recognized experimental approach to non-alcoholic steatohepatitis, while thioacetamide- (TAA) induced liver fibrosis resembles alcoholic liver fibrogenesis. In order to elucidate the effect of TAA on liver extracellular matrix composition under choline deprivation due to choline-deficient diet (CDD) administration, we evaluated the transcriptional and immunohistochemical (IHC) pattern of major hepatic matrix metalloproteinases (namely, MMP-2, -9) and their tissue inhibitors (TIMP-1, -2) in adult male albino Wistar rats at 30, 60 and 90 days...
July 18, 2018: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/30013742/non-celiac-gluten-sensitivity-and-diagnostic-challenges
#18
REVIEW
Giovanni Casella, Vincenzo Villanacci, Camillo Di Bella, Gabrio Bassotti, Justine Bold, Kamran Rostami
Non-celiac gluten sensitivity (NCGS), also referred to as non-celiac wheat sensitivity (NCWS), is a clinical syndrome characterized by both intestinal and extra-intestinal symptoms responsive to the withdrawal of gluten-containing food from the diet. The aim of this review is to summarize recent advances in research and provide a brief overview of the history of the condition for the benefit of professionals working in gastroenterology. Academic databases such as PubMed and Google Scholar were searched using key words such as "non-celiac gluten sensitivity", "gluten related disorders", and the studies outlined in reference page were selected and analysed...
2018: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/30013329/phosphate-control-adherence-in-hemodialysis-patients-current-perspectives
#19
REVIEW
Ebele M Umeukeje, Amanda S Mixon, Kerri L Cavanaugh
Objectives: This review summarizes factors relevant for adherence to phosphate-control strategies in dialysis patients, and discusses interventions to overcome related challenges. Methods: A literature search including the terms "phosphorus", "phosphorus control", "hemo-dialysis", "phosphate binder medications", "phosphorus diet", "adherence", and "nonadherence" was undertaken using PubMed, PsycInfo, CINAHL, and Embase...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/30011956/nutritional-interventions-as-beneficial-strategies-to-delay-cognitive-decline-in-healthy-older-individuals
#20
REVIEW
Blanka Klímová, Martin Vališ
Current demographic trends indicate that the population is aging. The aging process is inevitably connected with cognitive decline, which manifests itself in worsening working memory, processing speed, and attention. Therefore, apart from pharmacological therapies, non-pharmacological approaches which can influence cognitive performance (such as physical activities or healthy diet), are being investigated. The purpose of this study is to explore the types of nutritional interventions and their benefits in the prevention and delay of cognitive delay in healthy older individuals...
July 15, 2018: Nutrients
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