keyword
https://read.qxmd.com/read/37476118/exercise-induced-bronchoconstriction-among-adolescent-athletes-with-asthma-a-systematic-review
#21
REVIEW
Sawsan H Hashim, Miad I Alenezi, Rawan M Alenezi, Wafa T Alanazi, Mooj M Alruwaili, Almaha A Alali, Areej M Alanazi
Exercise-induced bronchoconstriction (EIB) is a concern that frequently affects athletes and regular exercisers. The main objective of this systematic review is to study recently published literature that evaluated the risk of EIB among adolescent athletes with asthma. PubMed, Web of Science, Science Direct, EBSCO, SCOPUS, Wiley, and Cochrane Library were searched. Study articles were screened by title and abstract using Rayyan QCRI then a full-text assessment was implemented. A total of ten studies with 3129 adolescent athletic subjects were included in this review...
June 2023: Curēus
https://read.qxmd.com/read/37432069/design-and-screening-of-fluorescent-probes-based-upon-hemicyanine-dyes-to-sensitively-respond-to-hso-3-in-living-cells
#22
JOURNAL ARTICLE
Bu-Yue Zhang, Xiu-Feng Zhang, Xiao-Ying Ma, Da-Wei Yang, Hong-Xia Sun, Ya-Lin Tang, Lei Shi
SO2 , a gas signaling molecule, can be produced endogenously in mitochondria. Its hydrolysate, HSO3 - , plays a key role in food preservation, cardiovascular relaxation, and other fields, suggesting that it is important to achieve its detection. Here, based on the Michael addition mechanism, four hemicyanine dye fluorescent probes ( ETN , ETB , STB , and EIB ) were designed and synthesized for responding to HSO3 - . We evaluated the reaction ability of different probes with HSO3 - and tried to explain the reasons for the significantly different response effects between probes and HSO3 - according to the structure-activity relationship...
July 11, 2023: Journal of Organic Chemistry
https://read.qxmd.com/read/37394043/microwave-assisted-autohydrolysis-of-avocado-seed-for-the-recovery-of-antioxidant-phenolics-and-glucose
#23
JOURNAL ARTICLE
Alexandra Del Castillo-Llamosas, Gemma Eibes, Pedro Ferreira-Santos, Alba Pérez-Pérez, Pablo G Del-Río, Beatriz Gullón
This study describes the valorization of avocado seed (AS) within a green biorefinery concept using microwave-assisted autohydrolysis. After the treatment at temperatures of 150-230 °C for 5 min, the resulting solid and liquor were characterized. The temperature of 220 °C led to the simultaneous optimal values of antioxidant phenolics/flavonoids (42.15 mg GAE/g AS, 31, 89 RE/g AS, respectively) and glucose + glucooligosaccharides (38.82 g/L) in the liquor...
June 30, 2023: Bioresource Technology
https://read.qxmd.com/read/37366805/effect-of-hydration-on-pulmonary-function-and-development-of-exercise-induced-bronchoconstriction-among-professional-male-cyclists
#24
JOURNAL ARTICLE
Konstantinos M Pigakis, Vasileios T Stavrou, Ioannis Pantazopoulos, Zoe Daniil, Aggeliki K Kontopodi-Pigaki, Konstantinos Gourgoulianis
BACKGROUND: Exercise-induced bronchoconstriction (EIB) is a common problem in elite athletes. Classical pathways in the development of EIB include the osmotic and thermal theory as well as the presence of epithelial injury in the airway, with local water loss being the main trigger of EIB. This study aimed to investigate the effects of systemic hydration on pulmonary function and to establish whether it can reverse dehydration-induced alterations in pulmonary function. MATERIALS AND METHODS: This follow-up study was performed among professional cyclists, without a history of asthma and/or atopy...
June 7, 2023: Advances in Respiratory Medicine
https://read.qxmd.com/read/37336434/defining-the-contractile-prostanoid-component-in-hyperosmolar-induced-bronchoconstriction-in-human-small-airways
#25
REVIEW
Maria Belikova, Mamdoh Al-Ameri, Ann-Charlotte Orre, Jesper Säfholm
Exercise-induced bronchoconstriction (EIB) is thought to be triggered by increased osmolarity at the airway epithelium. The aim of this study was to define the contractile prostanoid component of EIB, using an ex vivo model where intact segments of bronchi (inner diameter 0.5-2mm) isolated from human lung tissue and subjected to mannitol. Exposure of bronchial segments to hyperosmolar mannitol evoked a contraction (64.3±3.5%) which could be prevented either by elimination of mast cells (15.8±4.3%) or a combination of cysteinyl leukotriene (cysLT1 ), histamine (H1 ) and thromboxane (TP) receptor antagonists (11...
June 17, 2023: Prostaglandins & Other Lipid Mediators
https://read.qxmd.com/read/37287280/prior-memory-encoding-of-negative-distractors-biases-emotion-induced-blindness
#26
JOURNAL ARTICLE
Lei Jia, Yuling Zhao, Billy Sung, Mengru Cheng, Xiaoqin Wang, Jun Wang
Previous research has shown that the proactive deprioritization of emotional distractors through the provision of information about the distractors or passive habituation of emotional distractors may attenuate emotion-induced blindness (EIB) in the rapid serial visual presentation stream. However, whether prior memory encoding of emotional distractors could bias the EIB effect remains unknown. To address this question, this study employed a three-phase paradigm integrating an item-method direct forgetting (DF) procedure with a classic EIB procedure...
June 7, 2023: Cognition & Emotion
https://read.qxmd.com/read/37216553/microtubule-detyrosination-drives-symmetry-breaking-to-polarize-cells-for-directed-cell-migration
#27
JOURNAL ARTICLE
Kirstine Lavrsen, Girish Rajendraprasad, Marcin Leda, Susana Eibes, Elisa Vitiello, Vasileios Katopodis, Andrew B Goryachev, Marin Barisic
To initiate directed movement, cells must become polarized, establishing a protrusive leading edge and a contractile trailing edge. This symmetry-breaking process involves reorganization of cytoskeleton and asymmetric distribution of regulatory molecules. However, what triggers and maintains this asymmetry during cell migration remains largely elusive. Here, we established a micropatterning-based 1D motility assay to investigate the molecular basis of symmetry breaking required for directed cell migration. We show that microtubule (MT) detyrosination drives cell polarization by directing kinesin-1-based transport of the adenomatous polyposis coli (APC) protein to cortical sites...
May 30, 2023: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/37215400/organizational-injustice-and-sickness-absence-the-moderating-role-of-locked-in-status
#28
JOURNAL ARTICLE
Paraskevi Peristera, Johanna Stengård, Constanze Eib, Claudia Bernhard-Oettel, Constanze Leineweber
Organizational injustice is known to negatively affect employees' health and to increase the risk for sickness absence. The negative health effects are also known to be more pronounced in uncontrollable, strain increasing, situations at the workplace. This study tests whether locked-in status, i.e., being stuck in a non-preferred workplace, modifies the associations between injustice perceptions and frequent (≥2 times/yr) and long (<mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mo>≥</mml:mo></mml:mrow></mml:math> 8 days/yr) sickness absence...
September 2023: SSM—Population Health
https://read.qxmd.com/read/37212596/distinct-epithelial-innate-immune-cell-transcriptional-circuits-underlie-airway-hyperresponsiveness-in-asthma
#29
JOURNAL ARTICLE
Ryan C Murphy, Ying Lai, Matthew Liu, Taha Al-Shaikhly, Matthew C Altman, William A Altemeier, Charles W Frevert, Jason S Debley, Adrian M Piliponsky, Steven F Ziegler, Sina A Gharib, Teal S Hallstrand
Rationale: Indirect airway hyperresponsiveness (AHR) is a highly specific feature of asthma, but the underlying mechanisms responsible for driving indirect AHR remain incompletely understood. Objectives: To identify differences in gene expression in epithelial brushings obtained from individuals with asthma who were characterized for indirect AHR in the form of exercise-induced bronchoconstriction (EIB). Methods: RNA-sequencing analysis was performed on epithelial brushings obtained from individuals with asthma with EIB ( n  = 11) and without EIB ( n  = 9)...
June 15, 2023: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/37181665/health-facility-delivery-and-early-initiation-of-breastfeeding-cross-sectional-survey-of-11-sub-saharan-african-countries
#30
JOURNAL ARTICLE
Edward K Ameyaw, Kenneth S Adde, Jones A Paintsil, Kwamena S Dickson, Olanrewaju Oladimeji, Sanni Yaya
BACKGROUND AND AIMS: Early initiation of breastfeeding (EIB) remains one of the promising interventions for preventing neonatal and child deaths. EIB is positively associated with healthcare delivery or childbirth. Meanwhile, no study in sub-Saharan Africa (SSA) appears to have investigated the relationship between health facility delivery and EIB; thus, we assessed the correlation between health facility delivery and EIB. METHODS: We used data from the Demographic and Health Survey (DHS) of 64,506 women from 11 SSA countries...
May 2023: Health Science Reports
https://read.qxmd.com/read/37174890/exercise-induced-bronchoconstriction-in-children-a-comparison-between-athletes-and-non-athletes
#31
JOURNAL ARTICLE
Kamila Malewska-Kaczmarek, Daniela Podlecka, Tymoteusz Mańkowski, Joanna Jerzyńska, Iwona Stelmach
Exercise-induced bronchoconstriction (EIB) is a dysfunction of the respiratory tract consisting of transient airflow obstruction. This study is a retrospective analysis of two prospective studies concerning EIB symptoms in two adolescent populations. Our study group included 400 non-athletes and 101 athletes. Due to the similarity of indoor exercise conditions, an analysis was performed on the basis of where training took place. The study aims to assess the EIB prevalence in the following groups of adolescent children: non-athletes and athletes...
May 8, 2023: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/37169331/valorization-of-bioethanol-by-products-to-produce-unspecific-peroxygenase-with-agrocybe-aegerita-technological-and-proteomic-perspectives
#32
JOURNAL ARTICLE
Sandra González-Rodríguez, Alba Trueba-Santiso, Thelmo A Lu-Chau, María Teresa Moreira, Gemma Eibes
Unspecific peroxygenase (UPO) presents a wide range of biotechnological applications. This study targets the use of by-products from bioethanol synthesis to produce UPO by Agrocybe aegerita. Solid-state and submerged fermentations (SSF and SmF) were evaluated, achieving the highest titers of UPO and laccase in SmF using vinasse as nutrients source. Optimized UPO production of 331U/L was achieved in 50% (v:v) vinasse with an inoculum grown for 14 days. These conditions were scaled-up to a 4L reactor, achieving a UPO activity of 265U/L...
May 9, 2023: New Biotechnology
https://read.qxmd.com/read/37133129/equal-intensity-beam-splitter-realization-by-wire-grid-polarizers-for-passive-laser-speckle-reduction
#33
JOURNAL ARTICLE
Zhaoxia Fan, Jinjia Liu, Yifei Ma, Mei Wang, Suotang Jia, Xuyuan Chen, Zhaomin Tong
A method to realize an equal-intensity beam splitter (EIBS) using wire grid polarizers (WGPs) is proposed. The EIBS consists of WGPs with predetermined orientations and high-reflectivity mirrors. We demonstrated the generation of three laser sub-beams (LSBs) with equivalent intensities using EIBS. The three LSBs were incoherent by introducing optical path differences larger than the laser coherence length. The LSBs were used to reduce speckle passively, where the objective speckle contrast was reduced from 0...
April 10, 2023: Applied Optics
https://read.qxmd.com/read/37082779/a-longitudinal-study-of-exercise-induced-bronchoconstriction-and-laryngeal-obstruction-in-high-school-athletes
#34
JOURNAL ARTICLE
Karin Ersson, Elisabet Mallmin, Leif Nordang, Andrei Malinovschi, Henrik Johansson
BACKGROUND: Exercise-induced bronchoconstriction (EIB) and exercise-induced laryngeal obstruction (EILO) are common in elite athletes. Knowledge of which factors are related to incident EIB and EILO is limited. The aim of this study was to explore the course of EIB and EILO in adolescent athletes over a 2 years period and baseline characteristics related to incident EIB. METHODS: Questionnaire data on respiratory symptoms, asthma, and aeroallergy and results of objective EIB and EILO tests were collected from 58 participants (27 tested for EILO) at baseline and after 2 years (follow-up)...
April 20, 2023: Scandinavian Journal of Medicine & Science in Sports
https://read.qxmd.com/read/37051807/fractional-exhaled-nitric-oxide-in-the-assessment-of-exercise-induced-bronchoconstriction-a-multicenter-retrospective-analysis-of-uk-based-athletes
#35
JOURNAL ARTICLE
John Dickinson, William Gowers, Savannah Sturridge, Neil Williams, Pascale Kippelen, Andrew Simpson, Anna Jackson, James H Hull, Oliver J Price
INTRODUCTION: Exercise-induced bronchoconstriction (EIB) is not only highly prevalent in people with asthma, but can also occur independently, particularly in athletes. Fractional exhaled nitric oxide (FeNO) is an indirect biomarker of type 2 airway inflammation that has an established role in the assessment and management of asthma. The aim was to evaluate the value of FeNO in the assessment of EIB in athletes. METHOD: Multicenter retrospective analysis. In total, 488 athletes (male: 76%) performed baseline FeNO, and spirometry pre- and post-indirect bronchial provocation via eucapnic voluntary hyperpnea (EVH)...
April 13, 2023: Scandinavian Journal of Medicine & Science in Sports
https://read.qxmd.com/read/37030028/avoiding-acid-crash-from-apple-pomace-hydrolysate-to-butanol-through-acetone-butanol-ethanol-fermentation-in-a-zero-waste-approach
#36
JOURNAL ARTICLE
Javier Bravo-Venegas, Inés Prado-Acebo, Beatriz Gullón, Thelmo A Lú-Chau, Gemma Eibes
Apple pomace (AP) is a lignocellulosic residue from the juice and cider industries that can be valorized in a multi-product biorefinery to generate multiple value-added compounds, including biofuels such as butanol. Butanol is produced biologically by acetone-butanol-ethanol (ABE) fermentation using bacteria of the genus Clostridium from sugar-based feedstocks. In this study, AP hydrolysate was used as a substrate for producing butanol by ABE fermentation. Various environmental factors influence the amount of butanol produced, but only under certain conditions the so-called 'acid crash', an undesirable phenomenon characterized by a total arrest of cell growth and solvent production, can be avoided...
April 6, 2023: Waste Management
https://read.qxmd.com/read/37009907/exercise-induced-bronchospasm-and-associated-factors-in-primary-school-children-a-cross-sectional-study
#37
JOURNAL ARTICLE
Ogochukwu C Ofiaeli, Chizalu I Ndukwu, Nwanneka O Ugwu, Kenechi O Nnamani, Joy C Ebenebe, Ifeoma Egbuonu
BACKGROUND: Exercise Induced Bronchospasm(EIB) is not equivalent to asthma. As many as 20%of school aged children are estimated to have EIB. In Nigeria, there is still a dearth of information on EIB as a clinical entity. This study determined the presence of EIB(using pre and post-exercise percentage difference in peak expiratory flow rate(PEFR) and associated factors such as age, gender, social class and nutritional status in primary school children in Nnewi, Anambra state, South-East Nigeria...
April 3, 2023: BMC Pediatrics
https://read.qxmd.com/read/37008496/targeting-market-segment-needs-with-public-good-crop-breeding-investments-a-case-study-with-potato-and-sweetpotato-focused-on-poverty-alleviation-nutrition-and-gender
#38
JOURNAL ARTICLE
Sylvester Okoth Ojwang, Julius Juma Okello, David Jakinda Otieno, Janet Mwende Mutiso, Hannele Lindqvist-Kreuze, Peter Coaldrake, Thiago Mendes, Maria Andrade, Neeraj Sharma, Wolfgang Gruneberg, Godwill Makunde, Reuben Ssali, Benard Yada, Sarah Mayanja, Vivian Polar, Bonny Oloka, Doreen M Chelangat, Jacqueline Ashby, Guy Hareau, Hugo Campos
Crop breeding programs have often focused on the release of new varieties that target yield improvement to achieve food security and reduce poverty. While continued investments in this objective are justified, there is a need for breeding programs to be increasingly more demand-driven and responsive to the changing customer preferences and population dynamics. This paper analyses the responsiveness of global potato and sweetpotato breeding programs pursued by the International Potato Center (CIP) and its partners to three major development indicators: poverty, malnutrition and gender...
2023: Frontiers in Plant Science
https://read.qxmd.com/read/36965010/asthma-and-exercise-induced-bronchoconstriction-in-athletes-diagnosis-treatment-and-anti-doping-challenges
#39
JOURNAL ARTICLE
Morten Hostrup, Erik S H Hansen, Søren M Rasmussen, Søren Jessen, Vibeke Backer
Athletes often experience lower airway dysfunction, such as asthma and exercise-induced bronchoconstriction (EIB), which affects more than half the athletes in some sports, not least in endurance sports. Symptoms include coughing, wheezing, and breathlessness, alongside airway narrowing, hyperresponsiveness, and inflammation. Early diagnosis and management are essential. Not only because untreated or poorly managed asthma and EIB potentially affects competition performance and training, but also because untreated airway inflammation can result in airway epithelial damage, remodeling, and fibrosis...
March 25, 2023: Scandinavian Journal of Medicine & Science in Sports
https://read.qxmd.com/read/36931729/glutamatergic-and-gabaergic-receptor-modulation-present-unique-electrophysiological-fingerprints-in-a-concentration-dependent-and-region-specific-manner
#40
JOURNAL ARTICLE
Irene Gonzalez-Burgos, Marie Bainier, Simon Gross, Philipp Schoenenberger, José A Ochoa-Martinez, Miguel Valencia, Roger L Redondo
Brain function depends on complex circuit interactions between excitatory and inhibitory neurons embedded in local and long-range networks. Systemic GABAA-receptor or NMDA-receptor modulation alters the excitatory/inhibitory balance (EIB), measurable with electroencephalography (EEG). However, EEG signatures are complex in localization and spectral composition. We developed and applied analytical tools to investigate the effects of two EIB modulators, MK801 (NMDAR-antagonist) and diazepam (GABAAR-modulator), on periodic and aperiodic EEG features in freely-moving male Sprague-Dawley rats...
March 16, 2023: ENeuro
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