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JOURNAL ARTICLE
Suijun Xiao, Yufei Lao, Hongbo Liu, Dacheng Li, Qiaoyan Wei, Liangdong Ye, Shaorong Lu
Developing high-performance hydrogels with anti-freeze, and antimicrobial properties is crucial for the practical application of flexible sensors. In this study, we prepared silver nanoparticles (AgNPs) with aloe polysaccharide (AP) as a reducing agent. Then, the AP/AgNPs were added to a system of polyvinyl alcohol and borax crosslinked in water/glycerol to obtain a multifunctional conductive hydrogel. The incorporated AgNPs improved the conductivity (0.39 S/m) and mechanical properties (elongation at break: 732...
April 11, 2024: International Journal of Biological Macromolecules
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JOURNAL ARTICLE
Fabio Alves Teixeira, Vivian Pedrinelli, Mariana Yukari Hayasaki Porsani, Brana Sanctos Alo Bonder, Ana Beatriz Fasolai, Marcio Antonio Brunetto
Obesity is a highly prevalent disease in dogs and is characterized by the excessive accumulation of adipose tissue that results in metabolic changes. Its treatment is based on a negative energy balance focusing on energy restriction. However, there are few studies in dogs that assessed the energy intake needed for adequate weight loss and to weight maintenance afterward. The aim of this study was to evaluate data about the treatment of canine obesity, with emphasis on energy restriction to induce weight loss and to maintain body weight (BW) and ideal body condition after weight loss...
April 13, 2024: Journal of Animal Physiology and Animal Nutrition
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JOURNAL ARTICLE
Viktor Filatov, Anna Sokolova, Natalya Savitskaya, Mariya Olkhovskaya, Andrey Varava, Egor Ilin, Elizaveta Patronova
Aquaporin 3 (AQP3) channels are tetrameric membrane-bound channels that facilitate the transport of water and other small solutes across cell membranes in the skin. Decreased AQP3 expression is associated with skin dryness, skin aging, psoriasis, and delayed wound healing. Thus, our study focused on a novel combination based on Aloe barbadensis leaf extract and trimethylglycine for targeted AQP3 regulation in skin keratinocytes and deep skin moisturization. Firstly, a dose-finding cytotoxicity assay of the selected substances was performed with a 2,5-diphenyl-2H-tetrazolium bromide (MTT) indicator on HaCaT cells...
March 29, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
#24
JOURNAL ARTICLE
Bolesław Szadkowski, Magdalena Śliwka-Kaszyńska, Anna Marzec
Functional antibacterial textile materials are in great demand in the medical sector. In this paper, we propose a facile, eco-friendly approach to the design of antibacterial biodegradable cotton fabrics. Cotton fiber fabrics were enhanced with a chitosan coating loaded with plant extracts and essential oils. We employed Fourier-transform infrared (FTIR) and X-ray photoelectron spectroscopy (XPS), UV-Vis spectrophotometry, optical microscopy, scanning electron microscopy (SEM), and thermogravimetric analysis (TGA) to characterize the color, structure, and thermal properties of the modified fabrics...
April 12, 2024: Scientific Reports
#25
JOURNAL ARTICLE
Xiao-Na Dong, Meng-Ting Li
OBJECTIVE: Aloperine (ALO) is an effective quinolizidine alkaloid. Previous research has demonstrated its antiarrhythmic effect by inhibiting voltage-gated sodium currents in rat ventricular myocytes. This study explored its effect on transient outward potassium currents (Ito ) in rat atrial myocytes to identify potential targets in the context of ion channel currents. METHODS: The Ito characteristics in rat atrial myocytes were recorded using a whole-cell patch-clamp technique...
2024: Frontiers in Pharmacology
#26
JOURNAL ARTICLE
Yu-Ning Huang, Kun-Chuan Chen, Jen-Hung Wang, Yun-Kuan Lin
Burn injuries cause severe pain, infection risks, psychological distress, financial burdens, and mortality, necessitating effective care. Aloe vera, a traditional burn remedy, shows wound healing potential, but its analgesic effects and efficacy with varying burn severity are uncertain. This study aims to investigate aloe vera's impact on wound healing, pain management, and infection prevention in burn patients. A systematic search on PubMed, Embase, and CENTRAL was performed on 9th October 2023 for randomized controlled trials (RCTs)...
April 12, 2024: Journal of Burn Care & Research: Official Publication of the American Burn Association
#27
JOURNAL ARTICLE
Manpreet Kaur, Prerna Gulati, Sugandha Verma, Parul Khare, Ruchi Garg, Jahnobi Dutta, Kumuda Rao
OBJECTIVE: This research assessed the efficiencies of aloe vera, 0.1% triamcinolone acetonide, and 5% amlexanox in the management of OLP. MATERIALS AND METHODS: A total of 120 participants diagnosed with oral lichen planus (OLP) were equally divided into three groups and treated with: aloe vera, (Group A), 0.1% triamcinolone acetonide (Group B), and 5% amlexanox (Group C) topical medicaments. The patients were evaluated for pain, using the visual analogue scale (VAS)...
February 2024: Journal of Pharmacy & Bioallied Sciences
#28
JOURNAL ARTICLE
Mehak Tariq, Vishwanath V Jalli, J Dhurubatha, Reeturaj Medhi, Kanchan Malawat, Inderjit M Gowdar, Sugandha Arya
AIM: The aim of the study is to compare the clinical efficacy of both the topical agents-aloe vera gel and Kenacort oral paste (0.1% triamcinolone acetonide) in patients with minor aphthous stomatitis. MATERIALS AND METHODS: 60 patients were recruited for the study and were randomly divided into two groups-Group A (aloe vera gel group) and Group B (Kenacort oral paste group). The baseline parameters were taken and recorded on the day of the first visit which included ulcer size, pain, and burning sensation...
February 2024: Journal of Pharmacy & Bioallied Sciences
#29
JOURNAL ARTICLE
V P Aswathy, Aarti Bains, Kandi Sridhar, Prince Chawla, Minaxi Sharma, Nemat Ali, Abdul Malik, Gulden Goksen
In recent years, there increment demand for healthier food options that can replace high-fat ingredients in bakery products without compromising their taste and texture. This research was focused on a formulation study of the blend of nano polysaccharides derived from aloe vera and guar gum at various concentrations. This study selected the blend concentration of 1 % aloe vera mucilage (AM) and 1 % guar gum (GG) due to its optimal gelling properties. Different magnetic stirring time durations were employed to formulate AGB (aloe vera guar gum blend)...
April 7, 2024: International Journal of Biological Macromolecules
#30
JOURNAL ARTICLE
Diwanshi Sharma, Ashima Sharma, Ritu Bala, Baljit Singh
Recently, various innovative advancements have been made in carbohydrate research to design versatile materials for biomedical applications. The current research focuses on the development of copolymeric hydrogel wound dressings (HWD) using a combination of aloe vera (AV) - sterculia gum (SG) - poly (vinylsulfonic acid) (VSA)-based with the aim to enhancing their efficacy in drug delivery (DD) applications. These hydrogel dressings were encapsulated with levofloxacin and lidocaine to address both microbial infection and pain...
April 5, 2024: International Journal of Biological Macromolecules
#31
JOURNAL ARTICLE
Scott E McIntosh, Luanne Freer, Colin K Grissom, George W Rodway, Gordon G Giesbrecht, Marion McDevitt, Christopher H Imray, Eric L Johnson, Prativa Pandey, Jennifer Dow, Peter H Hackett
The Wilderness Medical Society convened an expert panel to develop a set of evidence-based guidelines for the prevention and treatment of frostbite. We present a review of pertinent pathophysiology. We then discuss primary and secondary prevention measures and therapeutic management. Recommendations are made regarding each treatment and its role in management. These recommendations are graded on the basis of the quality of supporting evidence and balance between the benefits and risks or burdens for each modality according to methodology stipulated by the American College of Chest Physicians...
April 5, 2024: Wilderness & Environmental Medicine
#32
JOURNAL ARTICLE
Blanca Carrasco, Gloria Zaragoza, David M Arana, Yolanda Hernández-Hermida, Juan-Ignacio Alós
INTRODUCTION: Early and adequate treatment of bloodstream infections decreases patient morbidity and mortality. The objective is to develop a preliminary method for rapid antibiotic susceptibility testing (RAST) in enterobacteria with inducible chromosomal AmpC. METHODS: RAST was performed directly on spiked blood cultures of 49 enterobacteria with inducible chromosomal AmpC. Results were read at 4, 6 and 8h of incubation. Commercial broth microdilution was considered the reference method...
April 2024: Enfermedades infecciosas y microbiologia clinica
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JOURNAL ARTICLE
Mayank Roshan, Ila Singh, Ashutosh Vats, Manisha Behera, Dravin Pratap Singh, Devika Gautam, Shiveeli Rajput, Jitesh Tarak, Gopinath Packirisamy, Sachinandan De
Antimicrobial resistance (AMR) poses a serious threat to human, animal, and plant health on a global scale. Search and elimination techniques should be used to effectively counter the spread of methicillin-resistant Staphylococcus aureus (MRSA) infections. With only a few novel drugs in clinical development, the quest for plant-based alternatives to prevent the spread of antibiotic resistance among bacteria has accelerated. Treatment of MRSA infections is challenging owing to rapidly emerging resistance mechanisms coupled with their protective biofilms...
April 3, 2024: International Microbiology: the Official Journal of the Spanish Society for Microbiology
#34
JOURNAL ARTICLE
P W Crous, E R Osieck, R G Shivas, Y P Tan, S L Bishop-Hurley, F Esteve-Raventós, E Larsson, J J Luangsa-Ard, F Pancorbo, S Balashov, I G Baseia, T Boekhout, S Chandranayaka, D A Cowan, R H S F Cruz, P Czachura, S De la Peña-Lastra, F Dovana, B Drury, J Fell, A Flakus, R Fotedar, Ž Jurjević, A Kolecka, J Mack, G Maggs-Kölling, S Mahadevakumar, A Mateos, S Mongkolsamrit, W Noisripoom, M Plaza, D P Overy, M Piątek, M Sandoval-Denis, J Vauras, M J Wingfield, S E Abell, A Ahmadpour, A Akulov, F Alavi, Z Alavi, A Altés, P Alvarado, G Anand, N Ashtekar, B Assyov, G Banc-Prandi, K D Barbosa, G G Barreto, J-M Bellanger, J L Bezerra, D J Bhat, P Bilański, T Bose, F Bozok, J Chaves, D H Costa-Rezende, C Danteswari, V Darmostuk, G Delgado, S Denman, A Eichmeier, J Etayo, G Eyssartier, S Faulwetter, K G G Ganga, Y Ghosta, J Goh, J S Góis, D Gramaje, L Granit, M Groenewald, G Gulden, L F P Gusmão, A Hammerbacher, Z Heidarian, N Hywel-Jones, R Jankowiak, M Kaliyaperumal, O Kaygusuz, K Kezo, A Khonsanit, S Kumar, C H Kuo, T Læssøe, K P D Latha, M Loizides, S M Luo, J G Maciá-Vicente, P Manimohan, P A S Marbach, P Marinho, T S Marney, G Marques, M P Martín, A N Miller, F Mondello, G Moreno, K T Mufeeda, H Y Mun, T Nau, T Nkomo, A Okrasińska, J P A F Oliveira, R L Oliveira, D A Ortiz, J Pawłowska, M À Pérez-De-Gregorio, A R Podile, A Portugal, N Privitera, K C Rajeshkumar, I Rauf, B Rian, A Rigueiro-Rodríguez, G F Rivas-Torres, P Rodriguez-Flakus, M Romero-Gordillo, I Saar, M Saba, C D Santos, P V S R N Sarma, J L Siquier, S Sleiman, M Spetik, K R Sridhar, M Stryjak-Bogacka, K Szczepańska, H Taşkın, D S Tennakoon, D Thanakitpipattana, J Trovão, I Türkekul, A L van Iperen, P van 't Hof, G Vasquez, C M Visagie, B D Wingfield, P T W Wong, W X Yang, M Yarar, O Yarden, N Yilmaz, N Zhang, Y N Zhu, J Z Groenewald
Novel species of fungi described in this study include those from various countries as follows: Australia , Aschersonia mackerrasiae on whitefly, Cladosporium corticola on bark of Melaleuca quinquenervia , Penicillium nudgee from soil under Melaleuca quinquenervia , Pseudocercospora blackwoodiae on leaf spot of Persoonia falcata , and Pseudocercospora dalyelliae on leaf spot of Senna alata . Bolivia , Aspicilia lutzoniana on fully submersed siliceous schist in high-mountain streams, and Niesslia parviseta on the lower part and apothecial discs of Erioderma barbellatum on a twig...
June 2023: Persoonia
#35
JOURNAL ARTICLE
Aditya Jain, Shikha Yadav, Javed Khan
Wound healing is crucial for maintaining skin integrity and preventing complications from external threats. Various plants, such as Achillea millefolium, Aloe vera, Curcuma longa, Calendula officinalis, Camellia sinensis, Azadirachta indica, and Plantago, have demonstrated wound healing capabilities and have been used in herbal medicine for wound care. NLCs are second-generation lipid nanoparticles, blending solid and liquid lipids to improve medication loading and limit leakage. NLCs have been used in various applications, including cosmeceuticals, chemotherapy, gene therapy, and brain targeting...
April 1, 2024: Current Pharmaceutical Biotechnology
#36
JOURNAL ARTICLE
Cyrus Mugo, Oluwasanmi Adedokun, Oluwafemi David Alo, Nnenna Ezeokafor, Sylvester Adeyemi, Zipporah Kpamor, Leila Madueke, Ezekiel James, Sylvia Bolanle Adebajo, Bazghina-Werq Semo
During the COVID-19 pandemic, HIV programs scaled up differentiated service delivery (DSD) models for people living with HIV (PLHIV). We evaluated the effects of COVID-19 on HIV service delivery and viral suppression in facilities in Northern Nigeria, and determined factors associated with viral suppression among adolescents and adults. We analysed a cross-sectional survey data from facility heads, and retrospective, routinely collected patient data from 63 facilities for PLHIV ≥10 years old in care between April 2019-March 2021, defining study periods as "pre-COVID-19" (before April 2020) and "during COVID-19" (after April 2020)...
2024: PloS One
#37
JOURNAL ARTICLE
Woojin Kang, Imane Frouni, Cynthia Kwan, Louis Desbiens, Adjia Hamadjida, Philippe Huot
LY-404,039 is an orthosteric agonist at metabotropic glutamate 2 and 3 (mGlu2/3) receptors, with a possible additional agonist effect at dopamine D2 receptors. LY-404,039 and its pro-drug, LY-2140023, have previously been tested in clinical trials for psychiatric indications and could therefore be repurposed if they were shown to be efficacious in other conditions. We have recently demonstrated that the mGlu2/3 orthosteric agonist LY-354,740 alleviated L-3,4-dihydroxyphenylalanine (L-DOPA)-induced abnormal involuntary movements (AIMs) in the 6-hydroxydopamine (6-OHDA)-lesioned rat without hampering the anti-parkinsonian action of L-DOPA...
March 29, 2024: Behavioural Pharmacology
#38
JOURNAL ARTICLE
Moltot Getahun, Adisu Befekadu, Esayas Alemayehu
The growing problem of industrial pollution in developing countries, especially Ethiopia, has sparked serious issues about the quality of the water, particularly when it comes to the effluent from wet coffee processing industries. In response, this study investigates the potential of utilizing natural coagulants, Acanthus sennii C., Moringa stenopetala B., and Aloe vera L., either individually or in combination, for the treatment of coffee effluent. Methodologically, the study systematically varies operational parameters, including coagulant dose, pH levels, stirring speed, and stirring time, to evaluate their impact on coagulation efficiency...
April 15, 2024: Heliyon
#39
Yunrui Lu, Ramsey Steiner, Serin Han, Aruesha Srivastava, Neha Shaik, Matthew Chan, Alos Diallo, Tracy Punshon, Brian Jackson, Fred Kolling, Linda Vahdat, Louis Vaickus, Jonathan Marotti, Sunita Ho, Joshua Levy
SUMMARY: Elemental imaging provides detailed profiling of metal bioaccumulation, offering more precision than bulk analysis by targeting specific tissue areas. However, accurately identifying comparable tissue regions from elemental maps is challenging, requiring the integration of hematoxylin and eosin (H&E) slides for effective comparison. Facilitating the streamlined co-registration of Whole Slide Images (WSI) and elemental maps, TRACE enhances the analysis of tissue regions and elemental abundance in various pathological conditions...
March 11, 2024: bioRxiv
#40
Francisco José Navarro-Triviño, Leopoldo Borrego, Juan Francisco Silvestre-Salvador, Pedro Mercader-García, Ana M Giménez-Arnau, Francisco Javier Ortiz de Frutos, Tatiana Sanz-Sánchez, Gemma Melé-Ninot, Araceli Sánchez-Gilo, Violeta Zaragoza-Ninet, Esther Serra-Baldrich, Javier Miquel-Miquel, Susana Córdoba-Guijarro, Mercedes Rodríguez-Serna, Inmaculada Ruíz-González, José Manuel Carrascosa-Carrillo, Enrique Gómez de la Fuente, María Antonia Pastor-Nieto, Felipe Heras-Mendaza, Ricardo González-Pérez, Paloma Sánchez-Pedreño Guillén, Javier Sánchez-Pérez, María Elena Gatica-Ortega, Virginia Fernández-Redondo, Marcos Hervella-Garcés, Pilar Manrique-Martínez, Dolores Guimaraens-Juanena, Juan García-Gavín, Elena Giménez-Arnau, Ignaci Figueras-Nart, Laia Curto-Barredo, José Carlos Armario-Hita
After the meeting held by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC) back in October 2021, changes were suggested to the Spanish standard series patch testing. Hydroxyethyl methacrylate (2% pet.), textile dye mixt (6.6% pet.), linalool hydroperoxide (1% pet.), and limonene hydroperoxide (0.3% pet.) were, then, added to the series that agreed upon in 2016. Ethyldiamine and phenoxyethanol were excluded. Methyldibromoglutaronitrile, the mixture of sesquiterpene lactones, and hydroxyisohexyl 3-cyclohexene (Lyral) were alo added to the extended Spanish series of 2022...
March 29, 2024: Actas Dermo-sifiliográficas
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