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Marco Sbroscia, Ilaria Gianani, Emanuele Roccia, Valeria Cimini, Luca Mancino, Paolo Aloe, Marco Barbieri
The simplicity of a question, such as wondering whether or not correlations characterize a certain system, collides with the experimental difficulty of accessing such information. Here we present a low-demanding experimental approach that refers to the use of a metrology scheme to obtain a conservative estimate of the strength of frequency correlations. Our test bed is the widespread case of a photon pair produced per downconversion. The theoretical architecture used to put the correlation degree on a quantitative ground is also described...
August 15, 2018: Optics Letters
Martín C Grados, Israel J Thuissard, Juan-Ignacio Alós
AIM: To determine the patterns of antibiotic susceptibility of Escherichia coli strains isolated from adult patients with urinary tract infection (UTI), and to stratify the results by age and type of UTI to verify if there are statistically significant differences that can help physicians to prescribe better empirical antibiotherapy. DESIGN: Cross-sectional prospective study. LOCATION: Community of Getafe (Madrid). Primary care level. PARTICIPANTS: 100 E...
August 10, 2018: Atencion Primaria
Siyong Gu, Chien-Te Hsieh, Tzu-Wei Lin, Chun-Yao Yuan, Yasser Ashraf Gandomi, Jeng-Kuei Chang, Jianlin Li
Graphene sheets that can exhibit electrical conducting and semiconducting properties are highly desirable and have potential applications in fiber communications, photodetectors, solar cells, semiconductors, and broadband modulators. However, there is currently no efficient method that is able to tune the band gap of graphene sheets. This work adopts an efficient atomic layer oxidation (ALO) technique to cyclically increase the oxidation level of graphene sheets, thus, tuning their electrical conductance, band-gap structure, and photoluminescence (PL) response...
August 13, 2018: Nanoscale
Yang Xu, Qing Wang, Zhihui Yin, Xiaoyan Gao
The traditional studies on metabolism in liver microsomes were carried out in off-line form. In this paper, a rapid and convenient method for the study of metabolism of substrates in liver microsomes was established by means of ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS): on-line incubation and real-time detection of substrates in liver microsomes. The liver microsomal incubation system was placed in a sample chamber at 37 °C. On-line solid phase extraction (SPE) column was used for on-line sample treatment, its function was to enrich the drug prototype and its metabolites with weak polarity, and elute the phosphate in the samples...
August 2, 2018: Journal of Chromatography. A
Arif Oguz Altunel
Watershed planning is a major issue in Turkey and other parts of the world. Surrounded by seawater on almost three-quarters of its international borders and by sheer mountains along the coastal regions and throughout the country, Turkey experiences a range of climatic changes, which constantly shape its topography. Recently, the occurrences of floods, landslides, and torrents have increased, forcing decision-makers to come up with solutions to manage and rehabilitate the upper watersheds in order to stop or limit the impact of disasters on downstream areas...
August 10, 2018: Environmental Monitoring and Assessment
Alessandra Vecchione, Francesco Celandroni, Antonella Lupetti, Eleonora Favuzza, Rita Mencucci, Emilia Ghelardi
PURPOSE: The aim of this study was to evaluate the antimicrobial activity of a novel preservative-free lid wipe formulation containing Aloe vera gel and hyaluronic acid that is commercialized for the hygiene of the periocular area. METHODS: In vitro susceptibility testing of the solution contained in wipes against bacteria and fungi commonly colonizing the periocular area, both reference strains and multidrug-resistant (MDR) clinical isolates, was assessed following the CLSI M07-A9 and M27-A3 broth methods, respectively...
August 10, 2018: Journal of Ocular Pharmacology and Therapeutics
Gabriel Humberto Gomez-Rodriguez, Marco Antonio Lopez-Mata, Edith Valbuena-Gregorio, Ramon Gertrudis Valdez Melchor, Julio Cesar Campos-Garcia, Norma Patricia Silva-Beltran, Luis Quihui-Cota, Saul Ruiz-Cruz, Josue Juarez
Recently, pectin (PEC) and Aloe-gel (AG) have received great attention for their use in the encapsulation of hydrophobic bioactive compounds such as carvacrol (CAR). The aim of this study is to assess the physical, chemical and biological properties of a novel PEC/AG film and evaluate its capability to entrap CAR into microencapsulates. For this purpose, the casting method was used to prepare the PEC/AG membranes (70:30 % w/w). The CAR-loaded PEC/AG film were prepared adding different proportions of CAR (0...
August 10, 2018: Current Topics in Medicinal Chemistry
Rudolf Spunda, Jan Hruby, Pavel Mericka, Mikulas Mlcek, Ondrej Pecha, Kathrin Splith, Moritz Schmelzle, Felix Krenzien, Jaroslav Lindner, Ivan Matia, Miroslav Spacek
OBJECTIVES AND DESIGN: The aim of our study was to simulate in rats all aspects and techniques used in our new clinical program of cryopreserved alloarterial transplantation and investigate the influence of two immunosuppressive protocols with tacrolimus on acute rejection of these allografts. MATERIALS AND METHODS: Cryopreserved abdominal aortic grafts were transplanted between Brown-Norway and Lewis rats. Tacrolimus (0.2 mg/kg daily) was administered from day 1 to day 30 (TAC1) or from day 7 to day 30 (TAC7), respectively...
2018: PloS One
Hong Leng, Li Pu, Longjiang Xu, Xin Shi, Jiang Ji, Kun Chen
Aloe vera is a traditional wound‑healing medicine used for the treatment of skin disorders. Aloe polysaccharide (APS) is the main macromolecule of Aloe vera, which contributes to its function. Psoriasis is an immune‑mediated chronic inflammatory disease, which affects 2‑3% of the general population. The conventional remedies used to treat psoriasis demonstrate limited effects; therefore, natural products, including Aloe vera, are being taken into consideration. However, the effects of APS on the treatment of psoriasis and the underlying mechanisms remain to be elucidated...
July 25, 2018: Molecular Medicine Reports
Yunfei Ma, Tuo Tang, Lili Sheng, Ziqian Wang, Hong Tao, Qing Zhang, Yao Zhang, Zhilin Qi
The anti‑inflammatory effects of aloin, a bioactive ingredient extracted from Aloe vera, have been described previously. The present study aimed to assess these effects and explore the underlying molecular mechanisms. RAW264.7 cells were incubated with different doses of aloin (100, 150 and 200 µg/ml) and lipopolysaccharide (LPS; 100 ng/ml) for the indicated times. Then, inducible nitric oxide synthase (iNOS) and cyclooxygenase‑2 expression levels were detected by western blot analysis and reverse transcription polymerase chain reaction (RT‑PCR)...
July 31, 2018: International Journal of Molecular Medicine
Anzhen Chen, Lei Sun, Hang Yuan, Aiying Wu, Jingguang Lu, Shuangcheng Ma
Multi-component analysis is one of the key techniques for the overall quality control of traditional Chinese medicines. However, the shortage and high cost of reference substances are the greatest obstacles. The substitute method is an alternative solution. In the present study, 11 compounds of rhubarb were simultaneously determined by a method named "two reference substances for determination of multiple components", which includes a qualitative method with linear calibration using two reference substances and a quantitative method with a relative correction factor combined with ultra high performance liquid chromatography...
July 30, 2018: Journal of Separation Science
A O Adelopo, P I Haris, B Alo, K Huddersman, R O Jenkins
Heterogeneous composite wastes from landfills were evaluated as precursors for the generation of activated carbon (AC). A single-step chemical activation process was applied involving irradiation with microwave energy and impregnation with KOH. The average percentage yield of AC from active landfill precursor was higher than that from closed landfill for all depths sampled. Increase in impregnation ratio and irradiation power decreased the average percentage yield for both landfill precursors (active: 38.1 to 33...
July 30, 2018: Waste Management & Research
Sandhya Chandrakar, Ashwini Kumar Gupta
Endophytic actinomycetes are a rich source of novel antimicrobial compounds. The aim of this study was to evaluate the production of antimicrobial compound by endophytic Streptomyces sp. Av-R5 associated with root of Aloe vera against multidrug-resistant human pathogens. The 16S rRNA sequence of the isolate Av-R5 has been identified as Streptomyces parvulus NBRC 13193T (AB184326) and the sequence was submitted to the National Center for Biotechnology Information (NCBI) GenBank database (accession number KY771080)...
July 30, 2018: Probiotics and Antimicrobial Proteins
Leake Gebremeskel, Dayananda Bhoumik, Gereziher Geremedhin Sibhat, Kald Beshir Tuem
Background: Aloe megalacantha Baker (Xanthorrhoeaceae) is one of the Aloe species widely distributed in Ethiopia. The leaf latex of the plant is used for treatment of wounds, inflammation, and other multiple ailments in Ethiopian traditional medicine. Purpose: The aim of this study was to evaluate in vivo wound healing and anti-inflammatory activities of the leaf latex of Aloe megalacantha in mice. Methods: The wound healing activity of the leaf latex of the plant was studied topically by incorporating the latex in simple ointment base in a concentration of 5% (w/w) and 10% (w/w) using excision and incision models...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Jung M Seo, Suzie Cheng, Nadia Soliman, Zeenat Nabi, Long Pan
Regular usage of cosmetic products and drugs in dermatological vehicles may cause irritant contact dermatitis. For example, aluminum chloride (AlCl3 ), the most efficacious antiperspirant salt to treat hyperhidrosis, shows high irritancy potential. To mitigate the irritant contact dermatitis caused by topical application of products containing AlCl3 , we investigated the anti-irritating effects of aloe extract and taurine in vitro and in vivo . In an in vitro experiment, reconstructed human epidermis model, EpiDerm, was tested with AlCl3 in the presence or absence of taurine and aloe extract...
May 2018: Journal of Cosmetic Science
Vajihe Atashi, Ahmadreza Yazdannik, Hosein Mahjobipoor, Somayeh Ghafari, Reza Bekhradi, Hojatollah Yousefi
Objective: Mouth dryness is one of the most prevalent problems in Intensive Care Units (ICUs). It facilitates dental plaque formation. The aim of this study was to analyze the effects of Aloe vera -Peppermint (Veramin) moisturizing gel on mouth dryness and oral health among patients hospitalized in ICUs. Methods: This triple-blind two-group randomized placebo-controlled clinical trial was undertaken in 2016-2017 on a convenient sample of 80 patients. Patients were randomly allocated to an intervention and a placebo group...
April 2018: Journal of Research in Pharmacy Practice
Xue Jintao, Shi Yongli, Ye Liming, Yang Quanwei, Li Chunyan, Chen Xingyi, Jing Yun
Rhubarb (Rhei Radix et Rhizoma) is a classic herbal laxative medicine in Europe and a very famous natural medicine in Asia, especially in China. In this study, near-infrared spectroscopy (NIRS) was first used for rapid and simultaneous analysis of five main active components (chrysophanol, aloe-emodin, rhein, emodin and physcion) in rhubarb of 6 geographical origins, processing and spurious samples. A total of 124 samples (73 raw, 40 processed and 11 spurious samples) were collected. With the reference values determined by HPLC, two calibration strategies, partial least squares (PLS) as a linear regression method and artificial neural networks (ANN) as a non-linear regression method, were studied...
July 18, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Paula Montoya, Kelly Henao, Gianina Pérez, Carlos A Salazar, Jorge Calderón
BACKGROUND: Moisturizer is an important component of many cosmetic products. It helps to maintain the skin's integrity and its barrier functions. Recently, magnetic masks that seek to improve the properties of the skin have been developed and have become a new cosmetic trend. However, scientific proof of their stated properties is lacking. AIMS: To test whether iron oxide contained in a face mask with magnetic properties in an oily matrix with a freeze-dried aloe-vera base increases moisturization of the skin and improves skin barrier function...
July 24, 2018: Journal of Cosmetic Dermatology
Bahareh Mirzaalizadeh, Mehdi Sharif, Ahmad Daryani, Mohammad Ali Ebrahimzadeh, Mehryar Zargari, Shahabeddin Sarvi, Saeed Mehrzadi, Mohammad Taghi Rahimi, Zahra Mirabediny, Monireh Golpour, Mahbobeh Montazeri
Toxoplasmosis is a worldwide disease caused by the protozoan parasite Toxoplasma gondii (T. gondii), which is most commonly treated by pyrimethamine and sulfadiazine. However, this treatment presents several adverse side effects; Thus, new drugs with lower toxicities are urgently needed. In this study the anti-T. gondii activity of A. vera and Eucalyptus extracts were evaluated in vitro using a MTT (3-(4, 5-dimethylthiazol-2-yl) 2, 5-diphenyltetrazolium bromide) assay and in vivo by measuring the survival rates of mice infected with 2 × 103 tachyzoites of RH strain of T...
July 19, 2018: Experimental Parasitology
Marie Stéphanie Chekem Goka, Maurice Ducret Awouafack, Marc Lamshöft, Landry Lienou Lienou, Gildas Tetaping Mbemya, Fabrice Boyom Fekam, Pierre Tane, Phélix Bruno Telefo
Background Aloe buettneri, Dicliptera verticillata, Hibiscus macranthus and Justicia insularis are medicinal plants used in the western region of Cameroon to cure infertility among women. This experiment was designed to compare the effect of the aqueous extracts of A. buettneri (AAB), D. verticillata (ADV), H. macranthus (AHM), J. insularis (AJI), their mixture (AME) and the extract obtained from the mixture of their powders (AMP) on some parameters of reproduction. Materials and methods High-performance liquid chromatography coupled with the mass spectrometry (HPLC-MS) was used to detect the constituents of different extracts...
July 21, 2018: Journal of Basic and Clinical Physiology and Pharmacology
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